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A novel, clinically relevant use of a piglet model to study the effects of anesthetics on the developing brain.

Clinical and translational medicine

Whitaker EE, Bissonnette B, Miller AD, Koppert TL, Tobias JD, Pierson CR, Christofi FL.
PMID: 26757938
Clin Transl Med. 2016 Mar;5(1):2. doi: 10.1186/s40169-015-0079-9. Epub 2016 Jan 12.

BACKGROUND: Anesthesia-induced neurotoxicity research in the developing brain must rely upon an unimpeachable animal model and a standardized treatment approach. In this manner, identification of mechanisms of action may be undertaken. The goal of this study was to develop...

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Whitaker EE, Bissonnette B, Miller AD, et al. A novel, clinically relevant use of a piglet model to study the effects of anesthetics on the developing brain. Clin Transl Med. 2016;5(1):2doi: 10.1186/s40169-015-0079-9.
Whitaker, E. E., Bissonnette, B., Miller, A. D., Koppert, T. L., Tobias, J. D., Pierson, C. R., & Christofi, F. L. (2016). A novel, clinically relevant use of a piglet model to study the effects of anesthetics on the developing brain. Clinical and translational medicine, 5(1), 2. https://doi.org/10.1186/s40169-015-0079-9
Whitaker, Emmett E, et al. "A novel, clinically relevant use of a piglet model to study the effects of anesthetics on the developing brain." Clinical and translational medicine vol. 5,1 (2016): 2. doi: https://doi.org/10.1186/s40169-015-0079-9
Whitaker EE, Bissonnette B, Miller AD, Koppert TL, Tobias JD, Pierson CR, Christofi FL. A novel, clinically relevant use of a piglet model to study the effects of anesthetics on the developing brain. Clin Transl Med. 2016 Mar;5(1):2. doi: 10.1186/s40169-015-0079-9. Epub 2016 Jan 12. PMID: 26757938; PMCID: PMC4710621.
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Emergency Department-Initiated Palliative Care in Advanced Cancer: A Randomized Clinical Trial.

JAMA oncology

Grudzen CR, Richardson LD, Johnson PN, Hu M, Wang B, Ortiz JM, Kistler EA, Chen A, Morrison RS.
PMID: 26768772
JAMA Oncol. 2016 May 01;2(5):591-598. doi: 10.1001/jamaoncol.2015.5252.

IMPORTANCE: The delivery of palliative care is not standard of care within most emergency departments (EDs).OBJECTIVE: To compare quality of life, depression, health care utilization, and survival in ED patients with advanced cancer randomized to ED-initiated palliative care consultation...

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Grudzen CR, Richardson LD, Johnson PN, et al. Emergency Department-Initiated Palliative Care in Advanced Cancer: A Randomized Clinical Trial. JAMA Oncol. 2016;2(5):591-598doi: 10.1001/jamaoncol.2015.5252.
Grudzen, C. R., Richardson, L. D., Johnson, P. N., Hu, M., Wang, B., Ortiz, J. M., Kistler, E. A., Chen, A., & Morrison, R. S. (2016). Emergency Department-Initiated Palliative Care in Advanced Cancer: A Randomized Clinical Trial. JAMA oncology, 2(5), 591-598. https://doi.org/10.1001/jamaoncol.2015.5252
Grudzen, Corita R, et al. "Emergency Department-Initiated Palliative Care in Advanced Cancer: A Randomized Clinical Trial." JAMA oncology vol. 2,5 (2016): 591-598. doi: https://doi.org/10.1001/jamaoncol.2015.5252
Grudzen CR, Richardson LD, Johnson PN, Hu M, Wang B, Ortiz JM, Kistler EA, Chen A, Morrison RS. Emergency Department-Initiated Palliative Care in Advanced Cancer: A Randomized Clinical Trial. JAMA Oncol. 2016 May 01;2(5):591-598. doi: 10.1001/jamaoncol.2015.5252. PMID: 26768772.
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Surgical epicardial left atrial appendage closure:A true alternative.

Journal of atrial fibrillation

Salzberg S, Emmert M.
PMID: 29487681
J Atr Fibrillation. 2017 Dec 31;10(4):1655. doi: 10.4022/jafib.1655. eCollection 2017 Dec.

Left atrial appendage closure was originally described by Madden in 1949 who was the first to perform appendix amputation. This was a very invasive procedure with poor outcome, but preformed for stroke prevention. Much later, it was James Cox...

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Salzberg S, Emmert M. Surgical epicardial left atrial appendage closure:A true alternative. J Atr Fibrillation. 2017;10(4):1655doi: 10.4022/jafib.1655.
Salzberg, S., & Emmert, M. (2017). Surgical epicardial left atrial appendage closure:A true alternative. Journal of atrial fibrillation, 10(4), 1655. https://doi.org/10.4022/jafib.1655
Salzberg, Sacha, and Emmert, Maximillian. "Surgical epicardial left atrial appendage closure:A true alternative." Journal of atrial fibrillation vol. 10,4 (2017): 1655. doi: https://doi.org/10.4022/jafib.1655
Salzberg S, Emmert M. Surgical epicardial left atrial appendage closure:A true alternative. J Atr Fibrillation. 2017 Dec 31;10(4):1655. doi: 10.4022/jafib.1655. eCollection 2017 Dec. PMID: 29487681; PMCID: PMC5821632.
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Redirecting Innovation in U.S. Health Care: Options to Decrease Spending and Increase Value.

Rand health quarterly

Garber S, Gates SM, Keeler EB, Vaiana ME, Mulcahy AW, Lau C, Kellermann AL.
PMID: 28083317
Rand Health Q. 2014 Mar 01;4(1):3. eCollection 2014.

New medical technologies are a leading driver of U.S. health care spending. This article identifies promising policy options to change which medical technologies are created, with two related policy goals: (1) Reduce total health care spending with the smallest...

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Garber S, Gates SM, Keeler EB, et al. Redirecting Innovation in U.S. Health Care: Options to Decrease Spending and Increase Value. Rand Health Q. 2014;4(1):3
Garber, S., Gates, S. M., Keeler, E. B., Vaiana, M. E., Mulcahy, A. W., Lau, C., & Kellermann, A. L. (2014). Redirecting Innovation in U.S. Health Care: Options to Decrease Spending and Increase Value. Rand health quarterly, 4(1), 3.
Garber, Steven, et al. "Redirecting Innovation in U.S. Health Care: Options to Decrease Spending and Increase Value." Rand health quarterly vol. 4,1 (2014): 3.
Garber S, Gates SM, Keeler EB, Vaiana ME, Mulcahy AW, Lau C, Kellermann AL. Redirecting Innovation in U.S. Health Care: Options to Decrease Spending and Increase Value. Rand Health Q. 2014 Mar 01;4(1):3. eCollection 2014. PMID: 28083317; PMCID: PMC5051971.
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Dysflective cones: Visual function and cone reflectivity in long-term follow-up of acute bilateral foveolitis.

American journal of ophthalmology case reports

Tu JH, Foote KG, Lujan BJ, Ratnam K, Qin J, Gorin MB, Cunningham ET, Tuten WS, Duncan JL, Roorda A.
PMID: 29057371
Am J Ophthalmol Case Rep. 2017 Sep;7:14-19. doi: 10.1016/j.ajoc.2017.04.001. Epub 2017 Apr 12.

PURPOSE: Confocal adaptive optics scanning laser ophthalmoscope (AOSLO) images provide a sensitive measure of cone structure. However, the relationship between structural findings of diminished cone reflectivity and visual function is unclear. We used fundus-referenced testing to evaluate visual function...

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Tu JH, Foote KG, Lujan BJ, et al. Dysflective cones: Visual function and cone reflectivity in long-term follow-up of acute bilateral foveolitis. Am J Ophthalmol Case Rep. 2017;7:14-19doi: 10.1016/j.ajoc.2017.04.001.
Tu, J. H., Foote, K. G., Lujan, B. J., Ratnam, K., Qin, J., Gorin, M. B., Cunningham, E. T., Tuten, W. S., Duncan, J. L., & Roorda, A. (2017). Dysflective cones: Visual function and cone reflectivity in long-term follow-up of acute bilateral foveolitis. American journal of ophthalmology case reports, 714-19. https://doi.org/10.1016/j.ajoc.2017.04.001
Tu, Joanna H, et al. "Dysflective cones: Visual function and cone reflectivity in long-term follow-up of acute bilateral foveolitis." American journal of ophthalmology case reports vol. 7 (2017): 14-19. doi: https://doi.org/10.1016/j.ajoc.2017.04.001
Tu JH, Foote KG, Lujan BJ, Ratnam K, Qin J, Gorin MB, Cunningham ET, Tuten WS, Duncan JL, Roorda A. Dysflective cones: Visual function and cone reflectivity in long-term follow-up of acute bilateral foveolitis. Am J Ophthalmol Case Rep. 2017 Sep;7:14-19. doi: 10.1016/j.ajoc.2017.04.001. Epub 2017 Apr 12. PMID: 29057371; PMCID: PMC5644392.
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Noninfectious uveitis: strategies to optimize treatment compliance and adherence.

Clinical ophthalmology (Auckland, N.Z.)

Dolz-Marco R, Gallego-Pinazo R, Díaz-Llopis M, Cunningham ET, Arévalo JF.
PMID: 26316689
Clin Ophthalmol. 2015 Aug 18;9:1477-81. doi: 10.2147/OPTH.S36650. eCollection 2015.

Noninfectious uveitis includes a heterogenous group of sight-threatening ocular and systemic disorders. Significant progress has been made in the treatment of noninfectious uveitis in recent years, particularly with regard to the effective use of corticosteroids and non-corticosteroid immunosuppressive drugs,...

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Dolz-Marco R, Gallego-Pinazo R, Díaz-Llopis M, et al. Noninfectious uveitis: strategies to optimize treatment compliance and adherence. Clin Ophthalmol. 2015;9:1477-81doi: 10.2147/OPTH.S36650.
Dolz-Marco, R., Gallego-Pinazo, R., Díaz-Llopis, M., Cunningham, E. T., & Arévalo, J. F. (2015). Noninfectious uveitis: strategies to optimize treatment compliance and adherence. Clinical ophthalmology (Auckland, N.Z.), 91477-81. https://doi.org/10.2147/OPTH.S36650
Dolz-Marco, Rosa, et al. "Noninfectious uveitis: strategies to optimize treatment compliance and adherence." Clinical ophthalmology (Auckland, N.Z.) vol. 9 (2015): 1477-81. doi: https://doi.org/10.2147/OPTH.S36650
Dolz-Marco R, Gallego-Pinazo R, Díaz-Llopis M, Cunningham ET, Arévalo JF. Noninfectious uveitis: strategies to optimize treatment compliance and adherence. Clin Ophthalmol. 2015 Aug 18;9:1477-81. doi: 10.2147/OPTH.S36650. eCollection 2015. PMID: 26316689; PMCID: PMC4547652.
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Spinal anesthesia after intraoperative cardiac arrest during general anesthesia in an infant.

Local and regional anesthesia

Whitaker EE, Miler V, Bryant J, Proicou S, Jayanthi R, Tobias JD.
PMID: 28435322
Local Reg Anesth. 2017 Mar 31;10:25-29. doi: 10.2147/LRA.S123157. eCollection 2017.

Although generally safe and effective, severe perioperative complications, including cardiac arrest, may occur during general anesthesia in infants. With the emergence of evidence that specific anesthetic agents may affect future neurocognitive outcomes, there has been an increased focus on...

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Whitaker EE, Miler V, Bryant J, et al. Spinal anesthesia after intraoperative cardiac arrest during general anesthesia in an infant. Local Reg Anesth. 2017;10:25-29doi: 10.2147/LRA.S123157.
Whitaker, E. E., Miler, V., Bryant, J., Proicou, S., Jayanthi, R., & Tobias, J. D. (2017). Spinal anesthesia after intraoperative cardiac arrest during general anesthesia in an infant. Local and regional anesthesia, 1025-29. https://doi.org/10.2147/LRA.S123157
Whitaker, Emmett E, et al. "Spinal anesthesia after intraoperative cardiac arrest during general anesthesia in an infant." Local and regional anesthesia vol. 10 (2017): 25-29. doi: https://doi.org/10.2147/LRA.S123157
Whitaker EE, Miler V, Bryant J, Proicou S, Jayanthi R, Tobias JD. Spinal anesthesia after intraoperative cardiac arrest during general anesthesia in an infant. Local Reg Anesth. 2017 Mar 31;10:25-29. doi: 10.2147/LRA.S123157. eCollection 2017. PMID: 28435322; PMCID: PMC5386604.
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[Developmental capacities of abdominal imaginal discs in the blow-flycalliphora erythrocephala. Experimental investigations on the morphology of the abdomen].

Wilhelm Roux' Archiv fur Entwicklungsmechanik der Organismen

Emmert W.
PMID: 28304776
Wilhelm Roux Arch Entwickl Mech Org. 1972 Jun;169(2):87-133. doi: 10.1007/BF00649888.

The differentiation of abdominal imaginal discs of matureCalliphora erythrocephala larvae has been studied by thermocautery and extirpation of the discs, and by implanting them into larval hosts of the same age. The experiments give information on (a) the morphology...

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Emmert W. Entwicklungsleistungen abdominaler Imaginalscheiben vonCalliphora erythrocephala (Insecta, Diptera). Experimentelle Untersuchungen zur Morphologie des Abdomens. [Developmental capacities of abdominal imaginal discs in the blow-flycalliphora erythrocephala. Experimental investigations on the morphology of the abdomen]. Wilhelm Roux Arch Entwickl Mech Org. 1972;169(2):87-133doi: 10.1007/BF00649888.
Emmert, W. (1972). Entwicklungsleistungen abdominaler Imaginalscheiben vonCalliphora erythrocephala (Insecta, Diptera). Experimentelle Untersuchungen zur Morphologie des Abdomens. [Developmental capacities of abdominal imaginal discs in the blow-flycalliphora erythrocephala. Experimental investigations on the morphology of the abdomen]. Wilhelm Roux' Archiv fur Entwicklungsmechanik der Organismen, 169(2), 87-133. https://doi.org/10.1007/BF00649888
Emmert, Werner. "Entwicklungsleistungen abdominaler Imaginalscheiben vonCalliphora erythrocephala (Insecta, Diptera). Experimentelle Untersuchungen zur Morphologie des Abdomens." [Developmental capacities of abdominal imaginal discs in the blow-flycalliphora erythrocephala. Experimental investigations on the morphology of the abdomen]. Wilhelm Roux' Archiv fur Entwicklungsmechanik der Organismen vol. 169,2 (1972): 87-133. doi: https://doi.org/10.1007/BF00649888
Emmert W. Entwicklungsleistungen abdominaler Imaginalscheiben vonCalliphora erythrocephala (Insecta, Diptera). Experimentelle Untersuchungen zur Morphologie des Abdomens. [Developmental capacities of abdominal imaginal discs in the blow-flycalliphora erythrocephala. Experimental investigations on the morphology of the abdomen]. Wilhelm Roux Arch Entwickl Mech Org. 1972 Jun;169(2):87-133. doi: 10.1007/BF00649888. German. PMID: 28304776.
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Good syndrome and other causes of cytomegalovirus retinitis in HIV-negative patients-case report and comprehensive review of the literature.

Journal of ophthalmic inflammation and infection

Downes KM, Tarasewicz D, Weisberg LJ, Cunningham ET.
PMID: 26809342
J Ophthalmic Inflamm Infect. 2016 Dec;6(1):3. doi: 10.1186/s12348-016-0070-7. Epub 2016 Jan 25.

We describe a 65-year-old Thai woman who developed cytomegalovirus retinitis (CMVR) in the setting of Good syndrome-a rare, acquired partial immune deficiency caused by thymoma. The patient subsequently developed vitritis with cystoid macular edema (CME) similar to immune recovery...

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Downes KM, Tarasewicz D, Weisberg LJ, et al. Good syndrome and other causes of cytomegalovirus retinitis in HIV-negative patients-case report and comprehensive review of the literature. J Ophthalmic Inflamm Infect. 2016;6(1):3doi: 10.1186/s12348-016-0070-7.
Downes, K. M., Tarasewicz, D., Weisberg, L. J., & Cunningham, E. T. (2016). Good syndrome and other causes of cytomegalovirus retinitis in HIV-negative patients-case report and comprehensive review of the literature. Journal of ophthalmic inflammation and infection, 6(1), 3. https://doi.org/10.1186/s12348-016-0070-7
Downes, Kenneth M, et al. "Good syndrome and other causes of cytomegalovirus retinitis in HIV-negative patients-case report and comprehensive review of the literature." Journal of ophthalmic inflammation and infection vol. 6,1 (2016): 3. doi: https://doi.org/10.1186/s12348-016-0070-7
Downes KM, Tarasewicz D, Weisberg LJ, Cunningham ET. Good syndrome and other causes of cytomegalovirus retinitis in HIV-negative patients-case report and comprehensive review of the literature. J Ophthalmic Inflamm Infect. 2016 Dec;6(1):3. doi: 10.1186/s12348-016-0070-7. Epub 2016 Jan 25. PMID: 26809342; PMCID: PMC4726639.
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Dermatologische Tageskliniken vor dem Hintergrund der aktuellen Gesetzgebung zur Krankenhausfinanzierung.

Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG

Blaschke V, Brauns B, Schmidt C, Emmert S.
PMID: 28252862
J Dtsch Dermatol Ges. 2017 Mar;15(3):356-358. doi: 10.1111/ddg.13185.

No abstract available.

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Blaschke V, Brauns B, Schmidt C, et al. Dermatologische Tageskliniken vor dem Hintergrund der aktuellen Gesetzgebung zur Krankenhausfinanzierung. J Dtsch Dermatol Ges. 2017;15(3):356-358doi: 10.1111/ddg.13185.
Blaschke, V., Brauns, B., Schmidt, C., & Emmert, S. (2017). Dermatologische Tageskliniken vor dem Hintergrund der aktuellen Gesetzgebung zur Krankenhausfinanzierung. Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG, 15(3), 356-358. https://doi.org/10.1111/ddg.13185
Blaschke, Volker, et al. "Dermatologische Tageskliniken vor dem Hintergrund der aktuellen Gesetzgebung zur Krankenhausfinanzierung." Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG vol. 15,3 (2017): 356-358. doi: https://doi.org/10.1111/ddg.13185
Blaschke V, Brauns B, Schmidt C, Emmert S. Dermatologische Tageskliniken vor dem Hintergrund der aktuellen Gesetzgebung zur Krankenhausfinanzierung. J Dtsch Dermatol Ges. 2017 Mar;15(3):356-358. doi: 10.1111/ddg.13185. PMID: 28252862.
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Stereoselective Synthesis of HIV-1 Protease Inhibitor, DMP 323.

The Journal of organic chemistry

Pierce ME, Harris GD, Islam Q, Radesca LA, Storace L, Waltermire RE, Wat E, Jadhav PK, Emmett GC.
PMID: 11666958
J Org Chem. 1996 Jan 26;61(2):444-450. doi: 10.1021/jo951847u.

DMP 323, a potent HIV-1 protease inhibitor, has been synthesized by an efficient stereoselective process, amenable to large scale preparations. The core C(2) symmetric diol was synthesized by a stereoselective pinacol coupling of CBZ protected D-phenylalanine. Judicious selection of...

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Pierce ME, Harris GD, Islam Q, et al. Stereoselective Synthesis of HIV-1 Protease Inhibitor, DMP 323. J Org Chem. 1996;61(2):444-450doi: 10.1021/jo951847u.
Pierce, M. E., Harris, G. D., Islam, Q., Radesca, L. A., Storace, L., Waltermire, R. E., Wat, E., Jadhav, P. K., & Emmett, G. C. (1996). Stereoselective Synthesis of HIV-1 Protease Inhibitor, DMP 323. The Journal of organic chemistry, 61(2), 444-450. https://doi.org/10.1021/jo951847u
Pierce, Michael E., et al. "Stereoselective Synthesis of HIV-1 Protease Inhibitor, DMP 323." The Journal of organic chemistry vol. 61,2 (1996): 444-450. doi: https://doi.org/10.1021/jo951847u
Pierce ME, Harris GD, Islam Q, Radesca LA, Storace L, Waltermire RE, Wat E, Jadhav PK, Emmett GC. Stereoselective Synthesis of HIV-1 Protease Inhibitor, DMP 323. J Org Chem. 1996 Jan 26;61(2):444-450. doi: 10.1021/jo951847u. PMID: 11666958.
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The EPR-Spectral D Parameter of Photochemically Generated Cyclopentane-1,3-diyl Triplet Diradicals as a Quantitative Measure of Spin Delocalization in Vinyl-, Phenyl-, and Carbonyl-Substituted Radicals.

The Journal of organic chemistry

Adam W, Emmert O, Heidenfelder T.
PMID: 11674461
J Org Chem. 1999 May 14;64(10):3417-3421. doi: 10.1021/jo9817422.

The zero-field splitting parameter D of the localized cyclopentane-1,3-diyl triplet diradicals T, generated in a 2-methyltetrahydrofuran (MTHF) glass matrix at 77 K through photochemical deazetation of the corresponding azoalkanes 1-13, has been determined by EPR spectroscopy. It is demonstrated...

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Adam W, Emmert O, Heidenfelder T. The EPR-Spectral D Parameter of Photochemically Generated Cyclopentane-1,3-diyl Triplet Diradicals as a Quantitative Measure of Spin Delocalization in Vinyl-, Phenyl-, and Carbonyl-Substituted Radicals. J Org Chem. 1999;64(10):3417-3421doi: 10.1021/jo9817422.
Adam, W., Emmert, O., & Heidenfelder, T. (1999). The EPR-Spectral D Parameter of Photochemically Generated Cyclopentane-1,3-diyl Triplet Diradicals as a Quantitative Measure of Spin Delocalization in Vinyl-, Phenyl-, and Carbonyl-Substituted Radicals. The Journal of organic chemistry, 64(10), 3417-3421. https://doi.org/10.1021/jo9817422
Adam, Waldemar, et al. "The EPR-Spectral D Parameter of Photochemically Generated Cyclopentane-1,3-diyl Triplet Diradicals as a Quantitative Measure of Spin Delocalization in Vinyl-, Phenyl-, and Carbonyl-Substituted Radicals." The Journal of organic chemistry vol. 64,10 (1999): 3417-3421. doi: https://doi.org/10.1021/jo9817422
Adam W, Emmert O, Heidenfelder T. The EPR-Spectral D Parameter of Photochemically Generated Cyclopentane-1,3-diyl Triplet Diradicals as a Quantitative Measure of Spin Delocalization in Vinyl-, Phenyl-, and Carbonyl-Substituted Radicals. J Org Chem. 1999 May 14;64(10):3417-3421. doi: 10.1021/jo9817422. PMID: 11674461.
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Showing 1 to 12 of 286 entries