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Unveiling stem cell kinetics: prime time for integrating experimental and computational models.

Frontiers in oncology

Enderling H.
PMID: 24350056
Front Oncol. 2013 Nov 28;3:291. doi: 10.3389/fonc.2013.00291. eCollection 2013.

No abstract available.

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Enderling H. Unveiling stem cell kinetics: prime time for integrating experimental and computational models. Front Oncol. 2013;3:291doi: 10.3389/fonc.2013.00291.
Enderling, H. (2013). Unveiling stem cell kinetics: prime time for integrating experimental and computational models. Frontiers in oncology, 3291. https://doi.org/10.3389/fonc.2013.00291
Enderling, Heiko. "Unveiling stem cell kinetics: prime time for integrating experimental and computational models." Frontiers in oncology vol. 3 (2013): 291. doi: https://doi.org/10.3389/fonc.2013.00291
Enderling H. Unveiling stem cell kinetics: prime time for integrating experimental and computational models. Front Oncol. 2013 Nov 28;3:291. doi: 10.3389/fonc.2013.00291. eCollection 2013. PMID: 24350056; PMCID: PMC3842622.
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Visualisation of the numerical solution of partial differential equation systems in three space dimensions and its importance for mathematical models in biology.

Mathematical biosciences and engineering : MBE

Enderling H, Anderson AR, Chaplain MA, Rowe GW.
PMID: 20361833
Math Biosci Eng. 2006 Oct;3(4):571-82. doi: 10.3934/mbe.2006.3.571.

Numerical analysis and computational simulation of partial differential equation models in mathematical biology are now an integral part of the research in this field. Increasingly we are seeing the development of partial differential equation models in more than one...

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Enderling H, Anderson AR, Chaplain MA, et al. Visualisation of the numerical solution of partial differential equation systems in three space dimensions and its importance for mathematical models in biology. Math Biosci Eng. 2006;3(4):571-82doi: 10.3934/mbe.2006.3.571.
Enderling, H., Anderson, A. R., Chaplain, M. A., & Rowe, G. W. (2006). Visualisation of the numerical solution of partial differential equation systems in three space dimensions and its importance for mathematical models in biology. Mathematical biosciences and engineering : MBE, 3(4), 571-82. https://doi.org/10.3934/mbe.2006.3.571
Enderling, Heiko, et al. "Visualisation of the numerical solution of partial differential equation systems in three space dimensions and its importance for mathematical models in biology." Mathematical biosciences and engineering : MBE vol. 3,4 (2006): 571-82. doi: https://doi.org/10.3934/mbe.2006.3.571
Enderling H, Anderson AR, Chaplain MA, Rowe GW. Visualisation of the numerical solution of partial differential equation systems in three space dimensions and its importance for mathematical models in biology. Math Biosci Eng. 2006 Oct;3(4):571-82. doi: 10.3934/mbe.2006.3.571. PMID: 20361833.
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Association of Docosahexaenoic Acid and Arachidonic Acid Serum Levels With Retinopathy of Prematurity in Preterm Infants.

JAMA network open

Hellström A, Pivodic A, Gränse L, Lundgren P, Sjöbom U, Nilsson AK, Söderling H, Hård AL, Smith LEH, Löfqvist CA.
PMID: 34648010
JAMA Netw Open. 2021 Oct 01;4(10):e2128771. doi: 10.1001/jamanetworkopen.2021.28771.

IMPORTANCE: Supplementing preterm infants with long-chain polyunsaturated fatty acids (LC-PUFA) has been inconsistent in reducing the severity and incidence of retinopathy of prematurity (ROP). Furthermore, few studies have measured the long-term serum lipid levels after supplementation.OBJECTIVE: To assess whether...

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Hellström A, Pivodic A, Gränse L, et al. Association of Docosahexaenoic Acid and Arachidonic Acid Serum Levels With Retinopathy of Prematurity in Preterm Infants. JAMA Netw Open. 2021;4(10):e2128771doi: 10.1001/jamanetworkopen.2021.28771.
Hellström, A., Pivodic, A., Gränse, L., Lundgren, P., Sjöbom, U., Nilsson, A. K., Söderling, H., Hård, A. L., Smith, L. E. H., & Löfqvist, C. A. (2021). Association of Docosahexaenoic Acid and Arachidonic Acid Serum Levels With Retinopathy of Prematurity in Preterm Infants. JAMA network open, 4(10), e2128771. https://doi.org/10.1001/jamanetworkopen.2021.28771
Hellström, Ann, et al. "Association of Docosahexaenoic Acid and Arachidonic Acid Serum Levels With Retinopathy of Prematurity in Preterm Infants." JAMA network open vol. 4,10 (2021): e2128771. doi: https://doi.org/10.1001/jamanetworkopen.2021.28771
Hellström A, Pivodic A, Gränse L, Lundgren P, Sjöbom U, Nilsson AK, Söderling H, Hård AL, Smith LEH, Löfqvist CA. Association of Docosahexaenoic Acid and Arachidonic Acid Serum Levels With Retinopathy of Prematurity in Preterm Infants. JAMA Netw Open. 2021 Oct 01;4(10):e2128771. doi: 10.1001/jamanetworkopen.2021.28771. PMID: 34648010; PMCID: PMC8517742.
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Education and Outreach in Physical Sciences in Oncology.

Trends in cancer

Walker SA, Pham A, Nizzero S, Kim M, Riter B, Bletz J, Judge S, Phillips B, Noble D, Murray D, Wetzel E, Samson S, McMahon M, Flink C, Couch J, Tomlin C, Swanson K, Anderson ARA, Odde D, Shen H, Hughes S, Zahir N, Enderling H, Wolfram J.
PMID: 33168416
Trends Cancer. 2021 Jan;7(1):3-9. doi: 10.1016/j.trecan.2020.10.007. Epub 2020 Nov 07.

Physical sciences are often overlooked in the field of cancer research. The Physical Sciences in Oncology Initiative was launched to integrate physics, mathematics, chemistry, and engineering with cancer research and clinical oncology through education, outreach, and collaboration. Here, we...

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Walker SA, Pham A, Nizzero S, et al. Education and Outreach in Physical Sciences in Oncology. Trends Cancer. 2020;7(1):3-9doi: 10.1016/j.trecan.2020.10.007.
Walker, S. A., Pham, A., Nizzero, S., Kim, M., Riter, B., Bletz, J., Judge, S., Phillips, B., Noble, D., Murray, D., Wetzel, E., Samson, S., McMahon, M., Flink, C., Couch, J., Tomlin, C., Swanson, K., Anderson, A. R. A., Odde, D., Shen, H., Hughes, S., Zahir, N., Enderling, H., & Wolfram, J. (2021). Education and Outreach in Physical Sciences in Oncology. Trends in cancer, 7(1), 3-9. https://doi.org/10.1016/j.trecan.2020.10.007
Walker, Sierra A, et al. "Education and Outreach in Physical Sciences in Oncology." Trends in cancer vol. 7,1 (2021): 3-9. doi: https://doi.org/10.1016/j.trecan.2020.10.007
Walker SA, Pham A, Nizzero S, Kim M, Riter B, Bletz J, Judge S, Phillips B, Noble D, Murray D, Wetzel E, Samson S, McMahon M, Flink C, Couch J, Tomlin C, Swanson K, Anderson ARA, Odde D, Shen H, Hughes S, Zahir N, Enderling H, Wolfram J. Education and Outreach in Physical Sciences in Oncology. Trends Cancer. 2021 Jan;7(1):3-9. doi: 10.1016/j.trecan.2020.10.007. Epub 2020 Nov 07. PMID: 33168416; PMCID: PMC7895467.
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Mathematical Models of Cancer: When to Predict Novel Therapies, and When Not to.

Bulletin of mathematical biology

Brady R, Enderling H.
PMID: 31338741
Bull Math Biol. 2019 Oct;81(10):3722-3731. doi: 10.1007/s11538-019-00640-x. Epub 2019 Jul 23.

The number of publications on mathematical modeling of cancer is growing at an exponential rate, according to PubMed records, provided by the US National Library of Medicine and the National Institutes of Health. Seminal papers have initiated and promoted...

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Brady R, Enderling H. Mathematical Models of Cancer: When to Predict Novel Therapies, and When Not to. Bull Math Biol. 2019;81(10):3722-3731doi: 10.1007/s11538-019-00640-x.
Brady, R., & Enderling, H. (2019). Mathematical Models of Cancer: When to Predict Novel Therapies, and When Not to. Bulletin of mathematical biology, 81(10), 3722-3731. https://doi.org/10.1007/s11538-019-00640-x
Brady, Renee, and Enderling, Heiko. "Mathematical Models of Cancer: When to Predict Novel Therapies, and When Not to." Bulletin of mathematical biology vol. 81,10 (2019): 3722-3731. doi: https://doi.org/10.1007/s11538-019-00640-x
Brady R, Enderling H. Mathematical Models of Cancer: When to Predict Novel Therapies, and When Not to. Bull Math Biol. 2019 Oct;81(10):3722-3731. doi: 10.1007/s11538-019-00640-x. Epub 2019 Jul 23. PMID: 31338741; PMCID: PMC6764933.
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Association of Docosahexaenoic Acid and Arachidonic Acid Serum Levels With Retinopathy of Prematurity in Preterm Infants.

JAMA network open

Hellström A, Pivodic A, Gränse L, Lundgren P, Sjöbom U, Nilsson AK, Söderling H, Hård AL, Smith LEH, Löfqvist CA.
PMID: 34648010
JAMA Netw Open. 2021 Oct 01;4(10):e2128771. doi: 10.1001/jamanetworkopen.2021.28771.

IMPORTANCE: Supplementing preterm infants with long-chain polyunsaturated fatty acids (LC-PUFA) has been inconsistent in reducing the severity and incidence of retinopathy of prematurity (ROP). Furthermore, few studies have measured the long-term serum lipid levels after supplementation.OBJECTIVE: To assess whether...

Cite
Hellström A, Pivodic A, Gränse L, et al. Association of Docosahexaenoic Acid and Arachidonic Acid Serum Levels With Retinopathy of Prematurity in Preterm Infants. JAMA Netw Open. 2021;4(10):e2128771doi: 10.1001/jamanetworkopen.2021.28771.
Hellström, A., Pivodic, A., Gränse, L., Lundgren, P., Sjöbom, U., Nilsson, A. K., Söderling, H., Hård, A. L., Smith, L. E. H., & Löfqvist, C. A. (2021). Association of Docosahexaenoic Acid and Arachidonic Acid Serum Levels With Retinopathy of Prematurity in Preterm Infants. JAMA network open, 4(10), e2128771. https://doi.org/10.1001/jamanetworkopen.2021.28771
Hellström, Ann, et al. "Association of Docosahexaenoic Acid and Arachidonic Acid Serum Levels With Retinopathy of Prematurity in Preterm Infants." JAMA network open vol. 4,10 (2021): e2128771. doi: https://doi.org/10.1001/jamanetworkopen.2021.28771
Hellström A, Pivodic A, Gränse L, Lundgren P, Sjöbom U, Nilsson AK, Söderling H, Hård AL, Smith LEH, Löfqvist CA. Association of Docosahexaenoic Acid and Arachidonic Acid Serum Levels With Retinopathy of Prematurity in Preterm Infants. JAMA Netw Open. 2021 Oct 01;4(10):e2128771. doi: 10.1001/jamanetworkopen.2021.28771. PMID: 34648010; PMCID: PMC8517742.
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Tumor-immune ecosystem dynamics define an individual Radiation Immune Score to predict pan-cancer radiocurability.

Neoplasia (New York, N.Y.)

Alfonso JCL, Grass GD, Welsh E, Ahmed KA, Teer JK, Pilon-Thomas S, Harrison LB, Cleveland JL, Mulé JJ, Eschrich SA, Torres-Roca JF, Enderling H.
PMID: 34619428
Neoplasia. 2021 Nov;23(11):1110-1122. doi: 10.1016/j.neo.2021.09.003. Epub 2021 Oct 05.

Radiotherapy efficacy is the result of radiation-mediated cytotoxicity coupled with stimulation of antitumor immune responses. We develop an in silico 3-dimensional agent-based model of diverse tumor-immune ecosystems (TIES) represented as anti- or pro-tumor immune phenotypes. We validate the model...

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Alfonso JCL, Grass GD, Welsh E, et al. Tumor-immune ecosystem dynamics define an individual Radiation Immune Score to predict pan-cancer radiocurability. Neoplasia. 2021;23(11):1110-1122doi: 10.1016/j.neo.2021.09.003.
Alfonso, J. C. L., Grass, G. D., Welsh, E., Ahmed, K. A., Teer, J. K., Pilon-Thomas, S., Harrison, L. B., Cleveland, J. L., Mulé, J. J., Eschrich, S. A., Torres-Roca, J. F., & Enderling, H. (2021). Tumor-immune ecosystem dynamics define an individual Radiation Immune Score to predict pan-cancer radiocurability. Neoplasia (New York, N.Y.), 23(11), 1110-1122. https://doi.org/10.1016/j.neo.2021.09.003
Alfonso, Juan C L, et al. "Tumor-immune ecosystem dynamics define an individual Radiation Immune Score to predict pan-cancer radiocurability." Neoplasia (New York, N.Y.) vol. 23,11 (2021): 1110-1122. doi: https://doi.org/10.1016/j.neo.2021.09.003
Alfonso JCL, Grass GD, Welsh E, Ahmed KA, Teer JK, Pilon-Thomas S, Harrison LB, Cleveland JL, Mulé JJ, Eschrich SA, Torres-Roca JF, Enderling H. Tumor-immune ecosystem dynamics define an individual Radiation Immune Score to predict pan-cancer radiocurability. Neoplasia. 2021 Nov;23(11):1110-1122. doi: 10.1016/j.neo.2021.09.003. Epub 2021 Oct 05. PMID: 34619428; PMCID: PMC8502777.
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Intermittent radiotherapy as alternative treatment for recurrent high grade glioma: a modeling study based on longitudinal tumor measurements.

Scientific reports

Brüningk SC, Peacock J, Whelan CJ, Brady-Nicholls R, Yu HM, Sahebjam S, Enderling H.
PMID: 34642366
Sci Rep. 2021 Oct 12;11(1):20219. doi: 10.1038/s41598-021-99507-2.

Recurrent high grade glioma patients face a poor prognosis for which no curative treatment option currently exists. In contrast to prescribing high dose hypofractionated stereotactic radiotherapy (HFSRT, [Formula: see text] Gy [Formula: see text] 5 in daily fractions) with...

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Brüningk SC, Peacock J, Whelan CJ, et al. Intermittent radiotherapy as alternative treatment for recurrent high grade glioma: a modeling study based on longitudinal tumor measurements. Sci Rep. 2021;11(1):20219doi: 10.1038/s41598-021-99507-2.
Brüningk, S. C., Peacock, J., Whelan, C. J., Brady-Nicholls, R., Yu, H. M., Sahebjam, S., & Enderling, H. (2021). Intermittent radiotherapy as alternative treatment for recurrent high grade glioma: a modeling study based on longitudinal tumor measurements. Scientific reports, 11(1), 20219. https://doi.org/10.1038/s41598-021-99507-2
Brüningk, Sarah C, et al. "Intermittent radiotherapy as alternative treatment for recurrent high grade glioma: a modeling study based on longitudinal tumor measurements." Scientific reports vol. 11,1 (2021): 20219. doi: https://doi.org/10.1038/s41598-021-99507-2
Brüningk SC, Peacock J, Whelan CJ, Brady-Nicholls R, Yu HM, Sahebjam S, Enderling H. Intermittent radiotherapy as alternative treatment for recurrent high grade glioma: a modeling study based on longitudinal tumor measurements. Sci Rep. 2021 Oct 12;11(1):20219. doi: 10.1038/s41598-021-99507-2. PMID: 34642366; PMCID: PMC8511136.
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Intermittent Hormone Therapy Models Analysis and Bayesian Model Comparison for Prostate Cancer.

Bulletin of mathematical biology

Pasetto S, Enderling H, Gatenby RA, Brady-Nicholls R.
PMID: 34797430
Bull Math Biol. 2021 Nov 19;84(1):2. doi: 10.1007/s11538-021-00953-w.

The prostate is an exocrine gland of the male reproductive system dependent on androgens (testosterone and dihydrotestosterone) for development and maintenance. First-line therapy for prostate cancer includes androgen deprivation therapy (ADT), depriving both the normal and malignant prostate cells...

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Pasetto S, Enderling H, Gatenby RA, et al. Intermittent Hormone Therapy Models Analysis and Bayesian Model Comparison for Prostate Cancer. Bull Math Biol. 2021;84(1):2doi: 10.1007/s11538-021-00953-w.
Pasetto, S., Enderling, H., Gatenby, R. A., & Brady-Nicholls, R. (2021). Intermittent Hormone Therapy Models Analysis and Bayesian Model Comparison for Prostate Cancer. Bulletin of mathematical biology, 84(1), 2. https://doi.org/10.1007/s11538-021-00953-w
Pasetto, S, et al. "Intermittent Hormone Therapy Models Analysis and Bayesian Model Comparison for Prostate Cancer." Bulletin of mathematical biology vol. 84,1 (2021): 2. doi: https://doi.org/10.1007/s11538-021-00953-w
Pasetto S, Enderling H, Gatenby RA, Brady-Nicholls R. Intermittent Hormone Therapy Models Analysis and Bayesian Model Comparison for Prostate Cancer. Bull Math Biol. 2021 Nov 19;84(1):2. doi: 10.1007/s11538-021-00953-w. PMID: 34797430; PMCID: PMC8604892.
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Dynamics-Adapted Radiotherapy Dose (DARD) for Head and Neck Cancer Radiotherapy Dose Personalization.

Journal of personalized medicine

Zahid MU, Mohamed ASR, Caudell JJ, Harrison LB, Fuller CD, Moros EG, Enderling H.
PMID: 34834476
J Pers Med. 2021 Nov 01;11(11). doi: 10.3390/jpm11111124.

Standard of care radiotherapy (RT) doses have been developed as a one-size-fits all approach designed to maximize tumor control rates across a population. Although this has led to high control rates for head and neck cancer with 66-70 Gy,...

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Zahid MU, Mohamed ASR, Caudell JJ, et al. Dynamics-Adapted Radiotherapy Dose (DARD) for Head and Neck Cancer Radiotherapy Dose Personalization. J Pers Med. 2021;11(11)doi: 10.3390/jpm11111124.
Zahid, M. U., Mohamed, A. S. R., Caudell, J. J., Harrison, L. B., Fuller, C. D., Moros, E. G., & Enderling, H. (2021). Dynamics-Adapted Radiotherapy Dose (DARD) for Head and Neck Cancer Radiotherapy Dose Personalization. Journal of personalized medicine, 11(11), . https://doi.org/10.3390/jpm11111124
Zahid, Mohammad U, et al. "Dynamics-Adapted Radiotherapy Dose (DARD) for Head and Neck Cancer Radiotherapy Dose Personalization." Journal of personalized medicine vol. 11,11 (2021). doi: https://doi.org/10.3390/jpm11111124
Zahid MU, Mohamed ASR, Caudell JJ, Harrison LB, Fuller CD, Moros EG, Enderling H. Dynamics-Adapted Radiotherapy Dose (DARD) for Head and Neck Cancer Radiotherapy Dose Personalization. J Pers Med. 2021 Nov 01;11(11). doi: 10.3390/jpm11111124. PMID: 34834476; PMCID: PMC8622616.
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Simulating cancer: computational models in oncology.

Frontiers in oncology

Enderling H, Rejniak KA.
PMID: 24062986
Front Oncol. 2013 Sep 13;3:233. doi: 10.3389/fonc.2013.00233. eCollection 2013.

No abstract available.

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Enderling H, Rejniak KA. Simulating cancer: computational models in oncology. Front Oncol. 2013;3:233doi: 10.3389/fonc.2013.00233.
Enderling, H., & Rejniak, K. A. (2013). Simulating cancer: computational models in oncology. Frontiers in oncology, 3233. https://doi.org/10.3389/fonc.2013.00233
Enderling, Heiko, and Rejniak, Katarzyna Anna. "Simulating cancer: computational models in oncology." Frontiers in oncology vol. 3 (2013): 233. doi: https://doi.org/10.3389/fonc.2013.00233
Enderling H, Rejniak KA. Simulating cancer: computational models in oncology. Front Oncol. 2013 Sep 13;3:233. doi: 10.3389/fonc.2013.00233. eCollection 2013. PMID: 24062986; PMCID: PMC3772565.
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Cancer Stem Cells: A Minor Cancer Subpopulation that Redefines Global Cancer Features.

Frontiers in oncology

Enderling H, Hlatky L, Hahnfeldt P.
PMID: 23596563
Front Oncol. 2013 Apr 15;3:76. doi: 10.3389/fonc.2013.00076. eCollection 2013.

In recent years cancer stem cells (CSCs) have been hypothesized to comprise only a minor subpopulation in solid tumors that drives tumor initiation, progression, and metastasis; the so-called "cancer stem cell hypothesis." While a seemingly trivial statement about numbers,...

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Enderling H, Hlatky L, Hahnfeldt P. Cancer Stem Cells: A Minor Cancer Subpopulation that Redefines Global Cancer Features. Front Oncol. 2013;3:76doi: 10.3389/fonc.2013.00076.
Enderling, H., Hlatky, L., & Hahnfeldt, P. (2013). Cancer Stem Cells: A Minor Cancer Subpopulation that Redefines Global Cancer Features. Frontiers in oncology, 376. https://doi.org/10.3389/fonc.2013.00076
Enderling, Heiko, et al. "Cancer Stem Cells: A Minor Cancer Subpopulation that Redefines Global Cancer Features." Frontiers in oncology vol. 3 (2013): 76. doi: https://doi.org/10.3389/fonc.2013.00076
Enderling H, Hlatky L, Hahnfeldt P. Cancer Stem Cells: A Minor Cancer Subpopulation that Redefines Global Cancer Features. Front Oncol. 2013 Apr 15;3:76. doi: 10.3389/fonc.2013.00076. eCollection 2013. PMID: 23596563; PMCID: PMC3625721.
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Showing 1 to 12 of 43 entries