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Showing 1 to 4 of 4 entries
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AF-6 Protects Against Dopaminergic Dysfunction and Mitochondrial Abnormalities in .

Frontiers in cellular neuroscience

Basil AH, Sim JPL, Lim GGY, Lin S, Chan HY, Engelender S, Lim KL.
PMID: 28848400
Front Cell Neurosci. 2017 Aug 10;11:241. doi: 10.3389/fncel.2017.00241. eCollection 2017.

Afadin 6 (AF-6) is an F-actin binding multidomain-containing scaffolding protein that is known for its function in cell-cell adhesion. Interestingly, besides this well documented role, we recently found that AF-6 is a Parkin-interacting protein that augments Parkin/PINK1-mediated mitophagy. Notably,...

Laser myringotomy (L-myringotomy) and ventilating tubes: a preliminary comparative study.

Lasers in medical science

Englender M, Somech E, Harell M.
PMID: 24584813
Lasers Med Sci. 1999 Mar;14(1):62-6. doi: 10.1007/s101030050022.

A prospective comparative study was done to assess the validity of laser myringotomy (L-myringotomy) when compared to the insertion of ventilating tubes (VT). In 23 children with chronic otitis media with effusion, a VT was inserted in the left...

SUMOylation in α-Synuclein Homeostasis and Pathology.

Frontiers in aging neuroscience

Savyon M, Engelender S.
PMID: 32670048
Front Aging Neurosci. 2020 Jun 25;12:167. doi: 10.3389/fnagi.2020.00167. eCollection 2020.

The accumulation and aggregation of α-synuclein are central to Parkinson's disease (PD), yet the molecular mechanisms responsible for these events are not fully understood. Post-translational modifications of α-synuclein regulate several of its properties, including degradation, interaction with proteins and...

Erratum to: Glycation potentiates α-synuclein-associated neurodegeneration in synucleinopathies.

Brain : a journal of neurology

Miranda HV, Szegő ÉM, Oliveira LMA, Breda C, Darendelioglu E, de Oliveira RM, Ferreira DG, Gomes MA, Rott R, Oliveira M, Munari F, Enguita FJ, Simões T, Rodrigues EF, Heinrich M, Martins IC, Zamolo I, Riess O, Cordeiro C, Ponces-Freire A, Lashuel HA, Santos NC, Lopes LV, Xiang W, Jovin TM, Penque D, Engelender S, Zweckstetter M, Klucken J, Giorgini F, Quintas A, Outeiro TF.
PMID: 34100910
Brain. 2021 Jul 28;144(6):e58. doi: 10.1093/brain/awab175.

No abstract available.

Showing 1 to 4 of 4 entries