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Showing 1 to 12 of 16 entries
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Emergence and Utility of Nonspherical Particles in Biomedicine.

Industrial & engineering chemistry research

Fish MB, Thompson AJ, Fromen CA, Eniola-Adefeso O.
PMID: 27182109
Ind Eng Chem Res. 2015 Apr 29;54(16):4043-4059. doi: 10.1021/ie504452j. Epub 2015 Jan 26.

The importance of the size of targeted, spherical drug carriers has been previously explored and reviewed. Particle shape has emerged as an equally important parameter in determining the

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Fish MB, Thompson AJ, Fromen CA, et al. Emergence and Utility of Nonspherical Particles in Biomedicine. Ind Eng Chem Res. 2015;54(16):4043-4059doi: 10.1021/ie504452j.
Fish, M. B., Thompson, A. J., Fromen, C. A., & Eniola-Adefeso, O. (2015). Emergence and Utility of Nonspherical Particles in Biomedicine. Industrial & engineering chemistry research, 54(16), 4043-4059. https://doi.org/10.1021/ie504452j
Fish, Margaret B, et al. "Emergence and Utility of Nonspherical Particles in Biomedicine." Industrial & engineering chemistry research vol. 54,16 (2015): 4043-4059. doi: https://doi.org/10.1021/ie504452j
Fish MB, Thompson AJ, Fromen CA, Eniola-Adefeso O. Emergence and Utility of Nonspherical Particles in Biomedicine. Ind Eng Chem Res. 2015 Apr 29;54(16):4043-4059. doi: 10.1021/ie504452j. Epub 2015 Jan 26. PMID: 27182109; PMCID: PMC4864008.
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Polysalicylic Acid Polymer Microparticle Decoys Therapeutically Treat Acute Respiratory Distress Syndrome.

Advanced healthcare materials

Brannon ER, Kelley WJ, Newstead MW, Banka AL, Uhrich KE, O'Connor CE, Standiford TJ, Eniola-Adefeso O.
PMID: 34881524
Adv Healthc Mater. 2021 Dec 08;e2101534. doi: 10.1002/adhm.202101534. Epub 2021 Dec 08.

Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) remain problematic due to high mortality rates and lack of effective treatments. Neutrophilic injury contributes to mortality in ALI/ARDS. Here, technology for rapid ARDS intervention is developed and evaluated,...

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Brannon ER, Kelley WJ, Newstead MW, et al. Polysalicylic Acid Polymer Microparticle Decoys Therapeutically Treat Acute Respiratory Distress Syndrome. Adv Healthc Mater. 2021;e2101534doi: 10.1002/adhm.202101534.
Brannon, E. R., Kelley, W. J., Newstead, M. W., Banka, A. L., Uhrich, K. E., O'Connor, C. E., Standiford, T. J., & Eniola-Adefeso, O. (2021). Polysalicylic Acid Polymer Microparticle Decoys Therapeutically Treat Acute Respiratory Distress Syndrome. Advanced healthcare materials, e2101534. https://doi.org/10.1002/adhm.202101534
Brannon, Emma R, et al. "Polysalicylic Acid Polymer Microparticle Decoys Therapeutically Treat Acute Respiratory Distress Syndrome." Advanced healthcare materials vol. (2021): e2101534. doi: https://doi.org/10.1002/adhm.202101534
Brannon ER, Kelley WJ, Newstead MW, Banka AL, Uhrich KE, O'Connor CE, Standiford TJ, Eniola-Adefeso O. Polysalicylic Acid Polymer Microparticle Decoys Therapeutically Treat Acute Respiratory Distress Syndrome. Adv Healthc Mater. 2021 Dec 08;e2101534. doi: 10.1002/adhm.202101534. Epub 2021 Dec 08. PMID: 34881524.
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Vascular-targeted particle binding efficacy in the presence of rigid red blood cells: Implications for performance in diseased blood.

Biomicrofluidics

Gutierrez M, Ojeda LS, Eniola-Adefeso O.
PMID: 30018696
Biomicrofluidics. 2018 Jun 25;12(4):042217. doi: 10.1063/1.5027760. eCollection 2018 Jul.

The field of drug delivery has taken an interest in combating numerous blood and heart diseases via the use of injectable vascular-targeted carriers (VTCs). However, VTC technology has encountered limited efficacy due to a variety of challenges associated with...

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Gutierrez M, Ojeda LS, Eniola-Adefeso O. Vascular-targeted particle binding efficacy in the presence of rigid red blood cells: Implications for performance in diseased blood. Biomicrofluidics. 2018;12(4):042217doi: 10.1063/1.5027760.
Gutierrez, M., Ojeda, L. S., & Eniola-Adefeso, O. (2018). Vascular-targeted particle binding efficacy in the presence of rigid red blood cells: Implications for performance in diseased blood. Biomicrofluidics, 12(4), 042217. https://doi.org/10.1063/1.5027760
Gutierrez, Mario, et al. "Vascular-targeted particle binding efficacy in the presence of rigid red blood cells: Implications for performance in diseased blood." Biomicrofluidics vol. 12,4 (2018): 042217. doi: https://doi.org/10.1063/1.5027760
Gutierrez M, Ojeda LS, Eniola-Adefeso O. Vascular-targeted particle binding efficacy in the presence of rigid red blood cells: Implications for performance in diseased blood. Biomicrofluidics. 2018 Jun 25;12(4):042217. doi: 10.1063/1.5027760. eCollection 2018 Jul. PMID: 30018696; PMCID: PMC6027197.
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Non-invasively visualizing cell-matrix interactions in two-photon excited supramolecular hydrogels.

Journal of materials chemistry. B

Ji W, Li L, Eniola-Adefeso O, Wang Y, Liu C, Feng C.
PMID: 32264379
J Mater Chem B. 2017 Oct 14;5(38):7790-7795. doi: 10.1039/c7tb02274c. Epub 2017 Sep 15.

Visualizing the role of extracellular matrix (ECM) in cell bioactivities in three-dimensional (3D) view is highly important for in-depth understanding of fundamental physiological issues in various in vitro experiments. Using current designs it is difficult to produce 3D biomimetic...

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Ji W, Li L, Eniola-Adefeso O, et al. Non-invasively visualizing cell-matrix interactions in two-photon excited supramolecular hydrogels. J Mater Chem B. 2017;5(38):7790-7795doi: 10.1039/c7tb02274c.
Ji, W., Li, L., Eniola-Adefeso, O., Wang, Y., Liu, C., & Feng, C. (2017). Non-invasively visualizing cell-matrix interactions in two-photon excited supramolecular hydrogels. Journal of materials chemistry. B, 5(38), 7790-7795. https://doi.org/10.1039/c7tb02274c
Ji, Wei, et al. "Non-invasively visualizing cell-matrix interactions in two-photon excited supramolecular hydrogels." Journal of materials chemistry. B vol. 5,38 (2017): 7790-7795. doi: https://doi.org/10.1039/c7tb02274c
Ji W, Li L, Eniola-Adefeso O, Wang Y, Liu C, Feng C. Non-invasively visualizing cell-matrix interactions in two-photon excited supramolecular hydrogels. J Mater Chem B. 2017 Oct 14;5(38):7790-7795. doi: 10.1039/c7tb02274c. Epub 2017 Sep 15. PMID: 32264379.
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Model Particulate Drug Carriers Modulate Leukocyte Adhesion in Human Blood Flows.

ACS biomaterials science & engineering

Kelley WJ, Onyskiw PJ, Fromen CA, Eniola-Adefeso O.
PMID: 33417805
ACS Biomater Sci Eng. 2019 Dec 09;5(12):6530-6540. doi: 10.1021/acsbiomaterials.9b01289. Epub 2019 Nov 06.

Drug carriers have been widely explored as a method of improving the efficacy of therapeutic drugs for a variety of diseases, including those involving inflammation. However, few of these formulations have advanced past clinical trials. There are still major...

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Kelley WJ, Onyskiw PJ, Fromen CA, et al. Model Particulate Drug Carriers Modulate Leukocyte Adhesion in Human Blood Flows. ACS Biomater Sci Eng. 2019;5(12):6530-6540doi: 10.1021/acsbiomaterials.9b01289.
Kelley, W. J., Onyskiw, P. J., Fromen, C. A., & Eniola-Adefeso, O. (2019). Model Particulate Drug Carriers Modulate Leukocyte Adhesion in Human Blood Flows. ACS biomaterials science & engineering, 5(12), 6530-6540. https://doi.org/10.1021/acsbiomaterials.9b01289
Kelley, William J, et al. "Model Particulate Drug Carriers Modulate Leukocyte Adhesion in Human Blood Flows." ACS biomaterials science & engineering vol. 5,12 (2019): 6530-6540. doi: https://doi.org/10.1021/acsbiomaterials.9b01289
Kelley WJ, Onyskiw PJ, Fromen CA, Eniola-Adefeso O. Model Particulate Drug Carriers Modulate Leukocyte Adhesion in Human Blood Flows. ACS Biomater Sci Eng. 2019 Dec 09;5(12):6530-6540. doi: 10.1021/acsbiomaterials.9b01289. Epub 2019 Nov 06. PMID: 33417805.
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Deformable microparticles for shuttling nanoparticles to the vascular wall.

Science advances

Fish MB, Banka AL, Braunreuther M, Fromen CA, Kelley WJ, Lee J, Adili R, Holinstat M, Eniola-Adefeso O.
PMID: 33883129
Sci Adv. 2021 Apr 21;7(17). doi: 10.1126/sciadv.abe0143. Print 2021 Apr.

Vascular-targeted drug carriers must localize to the wall (i.e., marginate) and adhere to a diseased endothelium to achieve clinical utility. The particle size has been reported as a critical physical property prescribing particle margination in vitro and in vivo...

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Fish MB, Banka AL, Braunreuther M, et al. Deformable microparticles for shuttling nanoparticles to the vascular wall. Sci Adv. 2021;7(17)doi: 10.1126/sciadv.abe0143.
Fish, M. B., Banka, A. L., Braunreuther, M., Fromen, C. A., Kelley, W. J., Lee, J., Adili, R., Holinstat, M., & Eniola-Adefeso, O. (2021). Deformable microparticles for shuttling nanoparticles to the vascular wall. Science advances, 7(17), . https://doi.org/10.1126/sciadv.abe0143
Fish, Margaret B, et al. "Deformable microparticles for shuttling nanoparticles to the vascular wall." Science advances vol. 7,17 (2021). doi: https://doi.org/10.1126/sciadv.abe0143
Fish MB, Banka AL, Braunreuther M, Fromen CA, Kelley WJ, Lee J, Adili R, Holinstat M, Eniola-Adefeso O. Deformable microparticles for shuttling nanoparticles to the vascular wall. Sci Adv. 2021 Apr 21;7(17). doi: 10.1126/sciadv.abe0143. Print 2021 Apr. PMID: 33883129; PMCID: PMC8059934.
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Method article: an .

Platelets

Banka AL, Eniola-Adefeso O.
PMID: 34927530
Platelets. 2021 Dec 20;1-8. doi: 10.1080/09537104.2021.1988550. Epub 2021 Dec 20.

No abstract available.

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Banka AL, Eniola-Adefeso O. Method article: an . Platelets. 2021;1-8doi: 10.1080/09537104.2021.1988550.
Banka, A. L., & Eniola-Adefeso, O. (2021). Method article: an . Platelets, 1-8. https://doi.org/10.1080/09537104.2021.1988550
Banka, Alison Leigh, and Eniola-Adefeso, Omolola. "Method article: an ." Platelets vol. (2021): 1-8. doi: https://doi.org/10.1080/09537104.2021.1988550
Banka AL, Eniola-Adefeso O. Method article: an . Platelets. 2021 Dec 20;1-8. doi: 10.1080/09537104.2021.1988550. Epub 2021 Dec 20. PMID: 34927530.
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Director Lander, the time is now.

Science (New York, N.Y.)

Eniola-Adefeso O, El-Samad H.
PMID: 34210855
Science. 2021 Jul 02;373(6550):7. doi: 10.1126/science.abk1976.

No abstract available.

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Eniola-Adefeso O, El-Samad H. Director Lander, the time is now. Science. 2021;373(6550):7doi: 10.1126/science.abk1976.
Eniola-Adefeso, O., & El-Samad, H. (2021). Director Lander, the time is now. Science (New York, N.Y.), 373(6550), 7. https://doi.org/10.1126/science.abk1976
Eniola-Adefeso, Omolola, and El-Samad, Hana. "Director Lander, the time is now." Science (New York, N.Y.) vol. 373,6550 (2021): 7. doi: https://doi.org/10.1126/science.abk1976
Eniola-Adefeso O, El-Samad H. Director Lander, the time is now. Science. 2021 Jul 02;373(6550):7. doi: 10.1126/science.abk1976. PMID: 34210855.
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Evaluation of Receptor-Ligand Mechanisms of Dual-Targeted Particles to an Inflamed Endothelium.

Bioengineering & translational medicine

Fromen CA, Fish MB, Zimmerman A, Adili R, Holinstat M, Eniola-Adefeso O.
PMID: 28066821
Bioeng Transl Med. 2016 Mar;1(1):103-115. doi: 10.1002/btm2.10008. Epub 2016 Apr 27.

Vascular-targeted carriers (VTCs) are designed as leukocyte mimics, decorated with ligands that target leukocyte adhesion molecules (LAMs) and facilitate adhesion to diseased endothelium. VTCs require different design considerations than other targeted particle therapies; adhesion of VTCs in regions with...

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Fromen CA, Fish MB, Zimmerman A, et al. Evaluation of Receptor-Ligand Mechanisms of Dual-Targeted Particles to an Inflamed Endothelium. Bioeng Transl Med. 2016;1(1):103-115doi: 10.1002/btm2.10008.
Fromen, C. A., Fish, M. B., Zimmerman, A., Adili, R., Holinstat, M., & Eniola-Adefeso, O. (2016). Evaluation of Receptor-Ligand Mechanisms of Dual-Targeted Particles to an Inflamed Endothelium. Bioengineering & translational medicine, 1(1), 103-115. https://doi.org/10.1002/btm2.10008
Fromen, Catherine A, et al. "Evaluation of Receptor-Ligand Mechanisms of Dual-Targeted Particles to an Inflamed Endothelium." Bioengineering & translational medicine vol. 1,1 (2016): 103-115. doi: https://doi.org/10.1002/btm2.10008
Fromen CA, Fish MB, Zimmerman A, Adili R, Holinstat M, Eniola-Adefeso O. Evaluation of Receptor-Ligand Mechanisms of Dual-Targeted Particles to an Inflamed Endothelium. Bioeng Transl Med. 2016 Mar;1(1):103-115. doi: 10.1002/btm2.10008. Epub 2016 Apr 27. PMID: 28066821; PMCID: PMC5217161.
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Modified two-step emulsion solvent evaporation technique for fabricating biodegradable rod-shaped particles in the submicron size range.

Journal of colloid and interface science

Safari H, Adili R, Holinstat M, Eniola-Adefeso O.
PMID: 29454188
J Colloid Interface Sci. 2018 May 15;518:174-183. doi: 10.1016/j.jcis.2018.02.030. Epub 2018 Feb 09.

HYPOTHESIS: Though the emulsion solvent evaporation (ESE) technique has been previously modified to produce rod-shaped particles, it cannot generate small-sized rods for drug delivery applications due to the inherent coupling and contradicting requirements for the formation versus stretching of...

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Safari H, Adili R, Holinstat M, et al. Modified two-step emulsion solvent evaporation technique for fabricating biodegradable rod-shaped particles in the submicron size range. J Colloid Interface Sci. 2018;518:174-183doi: 10.1016/j.jcis.2018.02.030.
Safari, H., Adili, R., Holinstat, M., & Eniola-Adefeso, O. (2018). Modified two-step emulsion solvent evaporation technique for fabricating biodegradable rod-shaped particles in the submicron size range. Journal of colloid and interface science, 518174-183. https://doi.org/10.1016/j.jcis.2018.02.030
Safari, Hanieh, et al. "Modified two-step emulsion solvent evaporation technique for fabricating biodegradable rod-shaped particles in the submicron size range." Journal of colloid and interface science vol. 518 (2018): 174-183. doi: https://doi.org/10.1016/j.jcis.2018.02.030
Safari H, Adili R, Holinstat M, Eniola-Adefeso O. Modified two-step emulsion solvent evaporation technique for fabricating biodegradable rod-shaped particles in the submicron size range. J Colloid Interface Sci. 2018 May 15;518:174-183. doi: 10.1016/j.jcis.2018.02.030. Epub 2018 Feb 09. PMID: 29454188; PMCID: PMC5862786.
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Biodegradable, bile salt microparticles for localized fat dissolution.

Science advances

Safari H, Kaczorowski N, Felder ML, Brannon ER, Varghese M, Singer K, Eniola-Adefeso O.
PMID: 33277261
Sci Adv. 2020 Dec 04;6(49). doi: 10.1126/sciadv.abd8019. Print 2020 Dec.

Bile acids are proposed as therapeutic agents for various diseases, including liver diseases and obesity. However, oral or subcutaneous administration of a solubilized version of these drugs has limited efficacy and imposes unwanted side effects. Here, we describe a...

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Safari H, Kaczorowski N, Felder ML, et al. Biodegradable, bile salt microparticles for localized fat dissolution. Sci Adv. 2020;6(49)doi: 10.1126/sciadv.abd8019.
Safari, H., Kaczorowski, N., Felder, M. L., Brannon, E. R., Varghese, M., Singer, K., & Eniola-Adefeso, O. (2020). Biodegradable, bile salt microparticles for localized fat dissolution. Science advances, 6(49), . https://doi.org/10.1126/sciadv.abd8019
Safari, Hanieh, et al. "Biodegradable, bile salt microparticles for localized fat dissolution." Science advances vol. 6,49 (2020). doi: https://doi.org/10.1126/sciadv.abd8019
Safari H, Kaczorowski N, Felder ML, Brannon ER, Varghese M, Singer K, Eniola-Adefeso O. Biodegradable, bile salt microparticles for localized fat dissolution. Sci Adv. 2020 Dec 04;6(49). doi: 10.1126/sciadv.abd8019. Print 2020 Dec. PMID: 33277261; PMCID: PMC7821899.
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IgA and IgM protein primarily drive plasma corona-induced adhesion reduction of PLGA nanoparticles in human blood flow.

Bioengineering & translational medicine

Sobczynski DJ, Eniola-Adefeso O.
PMID: 28932819
Bioeng Transl Med. 2017 May 22;2(2):180-190. doi: 10.1002/btm2.10064. eCollection 2017 Jun.

The high abundance of immunoglobulins (Igs) in the plasma protein corona on poly(lactic-co-glycolic) acid (PLGA)-based vascular-targeted carriers (VTCs) has previously been shown to reduce their adhesion to activated endothelial cells (aECs) in human blood flow. However, the relative role...

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Sobczynski DJ, Eniola-Adefeso O. IgA and IgM protein primarily drive plasma corona-induced adhesion reduction of PLGA nanoparticles in human blood flow. Bioeng Transl Med. 2017;2(2):180-190doi: 10.1002/btm2.10064.
Sobczynski, D. J., & Eniola-Adefeso, O. (2017). IgA and IgM protein primarily drive plasma corona-induced adhesion reduction of PLGA nanoparticles in human blood flow. Bioengineering & translational medicine, 2(2), 180-190. https://doi.org/10.1002/btm2.10064
Sobczynski, Daniel J, and Eniola-Adefeso, Omolola. "IgA and IgM protein primarily drive plasma corona-induced adhesion reduction of PLGA nanoparticles in human blood flow." Bioengineering & translational medicine vol. 2,2 (2017): 180-190. doi: https://doi.org/10.1002/btm2.10064
Sobczynski DJ, Eniola-Adefeso O. IgA and IgM protein primarily drive plasma corona-induced adhesion reduction of PLGA nanoparticles in human blood flow. Bioeng Transl Med. 2017 May 22;2(2):180-190. doi: 10.1002/btm2.10064. eCollection 2017 Jun. PMID: 28932819; PMCID: PMC5579729.
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