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Showing 1 to 6 of 6 entries
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Role of Human Organic Cation Transporter 1 (hOCT1) Polymorphisms in Lamivudine (3TC) Uptake and Drug-Drug Interactions.

Frontiers in pharmacology

Arimany-Nardi C, Minuesa G, Keller T, Erkizia I, Koepsell H, Martinez-Picado J, Pastor-Anglada M.
PMID: 27445813
Front Pharmacol. 2016 Jun 24;7:175. doi: 10.3389/fphar.2016.00175. eCollection 2016.

Lamivudine (3TC), a drug used in the treatment of HIV infection, needs to cross the plasma membrane to exert its therapeutic action. Human Organic cation transporter 1 (hOCT1), encoded by the SLC22A1 gene, is the transporter responsible for its...

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Arimany-Nardi C, Minuesa G, Keller T, et al. Role of Human Organic Cation Transporter 1 (hOCT1) Polymorphisms in Lamivudine (3TC) Uptake and Drug-Drug Interactions. Front Pharmacol. 2016;7:175doi: 10.3389/fphar.2016.00175.
Arimany-Nardi, C., Minuesa, G., Keller, T., Erkizia, I., Koepsell, H., Martinez-Picado, J., & Pastor-Anglada, M. (2016). Role of Human Organic Cation Transporter 1 (hOCT1) Polymorphisms in Lamivudine (3TC) Uptake and Drug-Drug Interactions. Frontiers in pharmacology, 7175. https://doi.org/10.3389/fphar.2016.00175
Arimany-Nardi, Cristina, et al. "Role of Human Organic Cation Transporter 1 (hOCT1) Polymorphisms in Lamivudine (3TC) Uptake and Drug-Drug Interactions." Frontiers in pharmacology vol. 7 (2016): 175. doi: https://doi.org/10.3389/fphar.2016.00175
Arimany-Nardi C, Minuesa G, Keller T, Erkizia I, Koepsell H, Martinez-Picado J, Pastor-Anglada M. Role of Human Organic Cation Transporter 1 (hOCT1) Polymorphisms in Lamivudine (3TC) Uptake and Drug-Drug Interactions. Front Pharmacol. 2016 Jun 24;7:175. doi: 10.3389/fphar.2016.00175. eCollection 2016. PMID: 27445813; PMCID: PMC4919327.
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Dissemination of .

Journal of extracellular vesicles

Benet S, Gálvez C, Drobniewski F, Kontsevaya I, Arias L, Monguió-Tortajada M, Erkizia I, Urrea V, Ong RY, Luquin M, Dupont M, Chojnacki J, Dalmau J, Cardona P, Neyrolles O, Lugo-Villarino G, Vérollet C, Julián E, Furrer H, Günthard HF, Crocker PR, Tapia G, Borràs FE, Fellay J, McLaren PJ, Telenti A, Cardona PJ, Clotet B, Vilaplana C, Martinez-Picado J, Izquierdo-Useros N.
PMID: 33489013
J Extracell Vesicles. 2021 Jan;10(3):e12046. doi: 10.1002/jev2.12046. Epub 2021 Jan 14.

The identification of individuals with null alleles enables studying how the loss of gene function affects infection. We previously described a non-functional variant in

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Benet S, Gálvez C, Drobniewski F, et al. Dissemination of . J Extracell Vesicles. 2021;10(3):e12046doi: 10.1002/jev2.12046.
Benet, S., Gálvez, C., Drobniewski, F., Kontsevaya, I., Arias, L., Monguió-Tortajada, M., Erkizia, I., Urrea, V., Ong, R. Y., Luquin, M., Dupont, M., Chojnacki, J., Dalmau, J., Cardona, P., Neyrolles, O., Lugo-Villarino, G., Vérollet, C., Julián, E., Furrer, H., Günthard, H. F., Crocker, P. R., Tapia, G., Borràs, F. E., Fellay, J., McLaren, P. J., Telenti, A., Cardona, P. J., Clotet, B., Vilaplana, C., Martinez-Picado, J., & Izquierdo-Useros, N. (2021). Dissemination of . Journal of extracellular vesicles, 10(3), e12046. https://doi.org/10.1002/jev2.12046
Benet, Susana, et al. "Dissemination of ." Journal of extracellular vesicles vol. 10,3 (2021): e12046. doi: https://doi.org/10.1002/jev2.12046
Benet S, Gálvez C, Drobniewski F, Kontsevaya I, Arias L, Monguió-Tortajada M, Erkizia I, Urrea V, Ong RY, Luquin M, Dupont M, Chojnacki J, Dalmau J, Cardona P, Neyrolles O, Lugo-Villarino G, Vérollet C, Julián E, Furrer H, Günthard HF, Crocker PR, Tapia G, Borràs FE, Fellay J, McLaren PJ, Telenti A, Cardona PJ, Clotet B, Vilaplana C, Martinez-Picado J, Izquierdo-Useros N. Dissemination of . J Extracell Vesicles. 2021 Jan;10(3):e12046. doi: 10.1002/jev2.12046. Epub 2021 Jan 14. PMID: 33489013; PMCID: PMC7807485.
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Silicate chain formation in the nanostructure of cement-based materials.

The Journal of chemical physics

Ayuela A, Dolado JS, Campillo I, de Miguel YR, Erkizia E, Sánchez-Portal D, Rubio A, Porro A, Echenique PM.
PMID: 17979374
J Chem Phys. 2007 Oct 28;127(16):164710. doi: 10.1063/1.2796171.

Cement-based materials are ubiquitous in almost all built environment. In spite of this, little is known about the formation and the role played by the silicate chains always present in the cement nanostructure. By means of first principles simulations...

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Ayuela A, Dolado JS, Campillo I, et al. Silicate chain formation in the nanostructure of cement-based materials. J Chem Phys. 2007;127(16):164710doi: 10.1063/1.2796171.
Ayuela, A., Dolado, J. S., Campillo, I., de Miguel, Y. R., Erkizia, E., Sánchez-Portal, D., Rubio, A., Porro, A., & Echenique, P. M. (2007). Silicate chain formation in the nanostructure of cement-based materials. The Journal of chemical physics, 127(16), 164710. https://doi.org/10.1063/1.2796171
Ayuela, A, et al. "Silicate chain formation in the nanostructure of cement-based materials." The Journal of chemical physics vol. 127,16 (2007): 164710. doi: https://doi.org/10.1063/1.2796171
Ayuela A, Dolado JS, Campillo I, de Miguel YR, Erkizia E, Sánchez-Portal D, Rubio A, Porro A, Echenique PM. Silicate chain formation in the nanostructure of cement-based materials. J Chem Phys. 2007 Oct 28;127(16):164710. doi: 10.1063/1.2796171. PMID: 17979374.
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Effect of addition of silica- and amine functionalized silica-nanoparticles on the microstructure of calcium silicate hydrate (C-S-H) gel.

Journal of colloid and interface science

Monasterio M, Gaitero JJ, Erkizia E, Guerrero Bustos AM, Miccio LA, Dolado JS, Cerveny S.
PMID: 25801139
J Colloid Interface Sci. 2015 Jul 15;450:109-118. doi: 10.1016/j.jcis.2015.02.066. Epub 2015 Mar 07.

In this work we study the influence of adding nano-silica (SiO2, Nyasil™) and aminopropyl (-(CH2)3-NH2,) functionalized silica nanoparticles (Stoga) during the synthesis of calcium-silicate-hydrate (C-S-H gel). Characterization by solid state (29)Si NMR and ATR-FTIR spectroscopy showed that the addition...

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Monasterio M, Gaitero JJ, Erkizia E, et al. Effect of addition of silica- and amine functionalized silica-nanoparticles on the microstructure of calcium silicate hydrate (C-S-H) gel. J Colloid Interface Sci. 2015;450:109-118doi: 10.1016/j.jcis.2015.02.066.
Monasterio, M., Gaitero, J. J., Erkizia, E., Guerrero Bustos, A. M., Miccio, L. A., Dolado, J. S., & Cerveny, S. (2015). Effect of addition of silica- and amine functionalized silica-nanoparticles on the microstructure of calcium silicate hydrate (C-S-H) gel. Journal of colloid and interface science, 450109-118. https://doi.org/10.1016/j.jcis.2015.02.066
Monasterio, Manuel, et al. "Effect of addition of silica- and amine functionalized silica-nanoparticles on the microstructure of calcium silicate hydrate (C-S-H) gel." Journal of colloid and interface science vol. 450 (2015): 109-118. doi: https://doi.org/10.1016/j.jcis.2015.02.066
Monasterio M, Gaitero JJ, Erkizia E, Guerrero Bustos AM, Miccio LA, Dolado JS, Cerveny S. Effect of addition of silica- and amine functionalized silica-nanoparticles on the microstructure of calcium silicate hydrate (C-S-H) gel. J Colloid Interface Sci. 2015 Jul 15;450:109-118. doi: 10.1016/j.jcis.2015.02.066. Epub 2015 Mar 07. PMID: 25801139.
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SARS-CoV-2 interaction with Siglec-1 mediates trans-infection by dendritic cells.

Cellular & molecular immunology

Perez-Zsolt D, Muñoz-Basagoiti J, Rodon J, Elosua-Bayes M, Raïch-Regué D, Risco C, Sachse M, Pino M, Gumber S, Paiardini M, Chojnacki J, Erkizia I, Muñiz-Trabudua X, Ballana E, Riveira-Muñoz E, Noguera-Julian M, Paredes R, Trinité B, Tarrés-Freixas F, Blanco I, Guallar V, Carrillo J, Blanco J, Telenti A, Heyn H, Segalés J, Clotet B, Martinez-Picado J, Vergara-Alert J, Izquierdo-Useros N.
PMID: 34782760
Cell Mol Immunol. 2021 Dec;18(12):2676-2678. doi: 10.1038/s41423-021-00794-6. Epub 2021 Nov 15.

No abstract available.

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Perez-Zsolt D, Muñoz-Basagoiti J, Rodon J, et al. SARS-CoV-2 interaction with Siglec-1 mediates trans-infection by dendritic cells. Cell Mol Immunol. 2021;18(12):2676-2678doi: 10.1038/s41423-021-00794-6.
Perez-Zsolt, D., Muñoz-Basagoiti, J., Rodon, J., Elosua-Bayes, M., Raïch-Regué, D., Risco, C., Sachse, M., Pino, M., Gumber, S., Paiardini, M., Chojnacki, J., Erkizia, I., Muñiz-Trabudua, X., Ballana, E., Riveira-Muñoz, E., Noguera-Julian, M., Paredes, R., Trinité, B., Tarrés-Freixas, F., Blanco, I., Guallar, V., Carrillo, J., Blanco, J., Telenti, A., Heyn, H., Segalés, J., Clotet, B., Martinez-Picado, J., Vergara-Alert, J., & Izquierdo-Useros, N. (2021). SARS-CoV-2 interaction with Siglec-1 mediates trans-infection by dendritic cells. Cellular & molecular immunology, 18(12), 2676-2678. https://doi.org/10.1038/s41423-021-00794-6
Perez-Zsolt, Daniel, et al. "SARS-CoV-2 interaction with Siglec-1 mediates trans-infection by dendritic cells." Cellular & molecular immunology vol. 18,12 (2021): 2676-2678. doi: https://doi.org/10.1038/s41423-021-00794-6
Perez-Zsolt D, Muñoz-Basagoiti J, Rodon J, Elosua-Bayes M, Raïch-Regué D, Risco C, Sachse M, Pino M, Gumber S, Paiardini M, Chojnacki J, Erkizia I, Muñiz-Trabudua X, Ballana E, Riveira-Muñoz E, Noguera-Julian M, Paredes R, Trinité B, Tarrés-Freixas F, Blanco I, Guallar V, Carrillo J, Blanco J, Telenti A, Heyn H, Segalés J, Clotet B, Martinez-Picado J, Vergara-Alert J, Izquierdo-Useros N. SARS-CoV-2 interaction with Siglec-1 mediates trans-infection by dendritic cells. Cell Mol Immunol. 2021 Dec;18(12):2676-2678. doi: 10.1038/s41423-021-00794-6. Epub 2021 Nov 15. PMID: 34782760; PMCID: PMC8591443.
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Identification of Plitidepsin as Potent Inhibitor of SARS-CoV-2-Induced Cytopathic Effect After a Drug Repurposing Screen.

Frontiers in pharmacology

Rodon J, Muñoz-Basagoiti J, Perez-Zsolt D, Noguera-Julian M, Paredes R, Mateu L, Quiñones C, Perez C, Erkizia I, Blanco I, Valencia A, Guallar V, Carrillo J, Blanco J, Segalés J, Clotet B, Vergara-Alert J, Izquierdo-Useros N.
PMID: 33841165
Front Pharmacol. 2021 Mar 25;12:646676. doi: 10.3389/fphar.2021.646676. eCollection 2021.

There is an urgent need to identify therapeutics for the treatment of Coronavirus disease 2019 (COVID-19). Although different antivirals are given for the clinical management of SARS-CoV-2 infection, their efficacy is still under evaluation. Here, we have screened existing...

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Rodon J, Muñoz-Basagoiti J, Perez-Zsolt D, et al. Identification of Plitidepsin as Potent Inhibitor of SARS-CoV-2-Induced Cytopathic Effect After a Drug Repurposing Screen. Front Pharmacol. 2021;12:646676doi: 10.3389/fphar.2021.646676.
Rodon, J., Muñoz-Basagoiti, J., Perez-Zsolt, D., Noguera-Julian, M., Paredes, R., Mateu, L., Quiñones, C., Perez, C., Erkizia, I., Blanco, I., Valencia, A., Guallar, V., Carrillo, J., Blanco, J., Segalés, J., Clotet, B., Vergara-Alert, J., & Izquierdo-Useros, N. (2021). Identification of Plitidepsin as Potent Inhibitor of SARS-CoV-2-Induced Cytopathic Effect After a Drug Repurposing Screen. Frontiers in pharmacology, 12646676. https://doi.org/10.3389/fphar.2021.646676
Rodon, Jordi, et al. "Identification of Plitidepsin as Potent Inhibitor of SARS-CoV-2-Induced Cytopathic Effect After a Drug Repurposing Screen." Frontiers in pharmacology vol. 12 (2021): 646676. doi: https://doi.org/10.3389/fphar.2021.646676
Rodon J, Muñoz-Basagoiti J, Perez-Zsolt D, Noguera-Julian M, Paredes R, Mateu L, Quiñones C, Perez C, Erkizia I, Blanco I, Valencia A, Guallar V, Carrillo J, Blanco J, Segalés J, Clotet B, Vergara-Alert J, Izquierdo-Useros N. Identification of Plitidepsin as Potent Inhibitor of SARS-CoV-2-Induced Cytopathic Effect After a Drug Repurposing Screen. Front Pharmacol. 2021 Mar 25;12:646676. doi: 10.3389/fphar.2021.646676. eCollection 2021. PMID: 33841165; PMCID: PMC8033486.
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Showing 1 to 6 of 6 entries