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Showing 1 to 12 of 114 entries
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The Absence of a Clinically Significant Effect of Food on the Single Dose Pharmacokinetics of Vorapaxar, a PAR-1 Antagonist, in Healthy Adult Subjects.

Clinical pharmacology in drug development

Behm MO, Kosoglou T, Miltenburg AM, Li J, Statkevich P, Johnson-Levonas AO, Martinho M, Fackler P.
PMID: 27121935
Clin Pharmacol Drug Dev. 2013 Oct;2(4):310-5. doi: 10.1002/cpdd.38.

In this open-label, randomized, 2-period crossover study, 16 healthy subjects received a single oral 2.5-mg dose of vorapaxar in the fed (i.e., standardized high-fat breakfast) and fasted (i.e., an overnight fast) state with a 6-week washout. Plasma samples for...

Electronic properties of gold(i) compounds relevance to chemical reactions.

Metal-based drugs

Fackler JP, Assefa Z, Forward JM, Grant TA.
PMID: 18475896
Met Based Drugs. 1999;6(4):223-31. doi: 10.1155/MBD.1999.223.

No abstract available.

Observation of muon neutrino disappearance with the MINOS detectors in the NuMI neutrino beam.

Physical review letters

Michael DG, Adamson P, Alexopoulos T, Allison WW, Alner GJ, Anderson K, Andreopoulos C, Andrews M, Andrews R, Arms KE, Armstrong R, Arroyo C, Auty DJ, Avvakumov S, Ayres DS, Baller B, Barish B, Barker MA, Barnes PD, Barr G, Barrett WL, Beall E, Becker BR, Belias A, Bergfeld T, Bernstein RH, Bhattacharya D, Bishai M, Blake A, Bocean V, Bock B, Bock GJ, Boehm J, Boehnlein DJ, Bogert D, Border PM, Bower C, Boyd S, Buckley-Geer E, Bungau C, Byon-Wagner A, Cabrera A, Chapman JD, Chase TR, Cherdack D, Chernichenko SK, Childress S, Choudhary BC, Cobb JH, Cossairt JD, Courant H, Crane DA, Culling AJ, Dawson JW, de Jong JK, DeMuth DM, De Santo A, Dierckxsens M, Diwan MV, Dorman M, Drake G, Drakoulakos D, Ducar R, Durkin T, Erwin AR, Escobar CO, Evans JJ, Fackler OD, Falk Harris E, Feldman GJ, Felt N, Fields TH, Ford R, Frohne MV, Gallagher HR, Gebhard M, Giurgiu GA, Godley A, Gogos J, Goodman MC, Gornushkin Y, Gouffon P, Gran R, Grashorn E, Grossman N, Grudzinski JJ, Grzelak K, Guarino V, Habig A, Halsall R, Hanson J, Harris D, Harris PG, Hartnell J, Hartouni EP, Hatcher R, Heller K, Hill N, Ho Y, Holin A, Howcroft C, Hylen J, Ignatenko M, Indurthy D, Irwin GM, Ishitsuka M, Jaffe DE, James C, Jenner L, Jensen D, Joffe-Minor T, Kafka T, Kang HJ, Kasahara SM, Kilmer J, Kim H, Kim MS, Koizumi G, Kopp S, Kordosky M, Koskinen DJ, Kostin M, Kotelnikov SK, Krakauer DA, Kreymer A, Kumaratunga S, Ladran AS, Lang K, Laughton C, Lebedev A, Lee R, Lee WY, Libkind MA, Ling J, Liu J, Litchfield PJ, Litchfield RP, Longley NP, Lucas P, Luebke W, Madani S, Maher E, Makeev V, Mann WA, Marchionni A, Marino AD, Marshak ML, Marshall JS, Mayer N, McDonald J, McGowan AM, Meier JR, Merzon GI, Messier MD, Milburn RH, Miller JL, Miller WH, Mishra SR, Mislivec A, Miyagawa PS, Moore CD, Morfín J, Morse R, Mualem L, Mufson S, Murgia S, Murtagh MJ, Musser J, Naples D, Nelson C, Nelson JK, Newman HB, Nezrick F, Nichol RJ, Nicholls TC, Ochoa-Ricoux JP, Oliver J, Oliver WP, Onuchin VA, Osiecki T, Ospanov R, Paley J, Paolone V, Para A, Patzak T, Pavlović Z, Pearce GF, Pearson N, Peck CW, Perry C, Peterson EA, Petyt DA, Ping H, Piteira R, Pittam R, Pla-Dalmau A, Plunkett RK, Price LE, Proga M, Pushka DR, Rahman D, Rameika RA, Raufer TM, Read AL, Rebel B, Reichenbacher J, Reyna DE, Rosenfeld C, Rubin HA, Ruddick K, Ryabov VA, Saakyan R, Sanchez MC, Saoulidou N, Schneps J, Schoessow PV, Schreiner P, Schwienhorst R, Semenov VK, Seun SM, Shanahan P, Shield PD, Smart W, Smirnitsky V, Smith C, Smith PN, Sousa A, Speakman B, Stamoulis P, Stefanik A, Sullivan P, Swan JM, Symes PA, Tagg N, Talaga RL, Terekhov A, Tetteh-Lartey E, Thomas J, Thompson J, Thomson MA, Thron JL, Tinti G, Trendler R, Trevor J, Trostin I, Tsarev VA, Tzanakos G, Urheim J, Vahle P, Vakili M, Vaziri K, Velissaris C, Verebryusov V, Viren B, Wai L, Ward CP, Ward DR, Watabe M, Weber A, Webb RC, Wehmann A, West N, White C, White RF, Wojcicki SG, Wright DM, Wu QK, Yan WG, Yang T, Yumiceva FX, Yun JC, Zheng H, Zois M, Zwaska R.
PMID: 17155614
Phys Rev Lett. 2006 Nov 10;97(19):191801. doi: 10.1103/PhysRevLett.97.191801. Epub 2006 Nov 08.

This Letter reports results from the MINOS experiment based on its initial exposure to neutrinos from the Fermilab NuMI beam. The rates and energy spectra of charged current nu(mu) interactions are compared in two detectors located along the beam...

The schizophrenias of childhood.

Journal of clinical and experimental psychopathology

SACKLER AM, SACKLER MD, SACKLER RR, TUI C.
PMID: 14897899
J Clin Exp Psychopathol. 1951 Jul-Sep;12(3):224-39.

No abstract available.

Syntheses of mixed-ligand tetranuclear gold(I)-nitrogen clusters by ligand exchange reactions with the dinuclear gold(I) formamidinate complex Au(2)(2,6-Me2Ph-form)2.

Inorganic chemistry

Abdou HE, Mohamed AA, Fackler JP.
PMID: 17198422
Inorg Chem. 2007 Jan 08;46(1):141-6. doi: 10.1021/ic0612449.

The reaction of the sterically crowded dinuclear gold(I) amidinate complex Au2(2,6-Me2Ph-form)2, 1, with the less bulky bidentate nitrogen ligands results in the formation of tetranuclear gold(I) complexes. When the less bulky amidinate, K(4-MePh-form), A, was reacted with 1 in...

Synthesis, characterization, and luminescent properties of dinuclear gold(I) xanthate complexes: X-ray structure of [Au2(nBu-xanthate)2].

Inorganic chemistry

Mohamed AA, Kani I, Ramirez AO, Fackler JP.
PMID: 15206863
Inorg Chem. 2004 Jun 28;43(13):3833-9. doi: 10.1021/ic0349858.

The synthesis and characterization of gold(I) complexes of butyl xanthate [Au(2)((n)()Bu-xanthate)(2)], 1, and ethyl xanthate [Au(2)(Et-xanthate)(2)], 2, are described. These complexes are readily prepared from the reaction between Au(THT)Cl (THT = tetrahydrothiophene) and the corresponding xanthate ligands as the...

Mixed-metal triangular trinuclear complexes: dimers of gold-silver mixed-metal complexes from gold(I) carbeniates and silver(I) 3,5-diphenylpyrazolates.

Journal of the American Chemical Society

Mohamed AA, Burini A, Fackler JP.
PMID: 15810823
J Am Chem Soc. 2005 Apr 13;127(14):5012-3. doi: 10.1021/ja0429869.

Dimers of trinuclear mixed gold-silver compounds are obtained by the reaction of a gold(I) carbeniate, [Au(mu-C(OEt)=NC6H4-p-CH3)]3, with a silver(I) pyrazolate, [Ag(mu-3,5-Ph2pz)]3. The crystalline products are the mixed-metal species Au(carb)Ag2(mu-3,5-Ph2pz)2 and Au2(carb)2Ag(mu-3,5-Ph2pz)CCH2Cl2.

C-F activation of fluorobenzene by silylium carboranes: evidence for incipient phenyl cation reactivity.

Angewandte Chemie (International ed. in English)

Duttwyler S, Douvris C, Fackler NL, Tham FS, Reed CA, Baldridge KK, Siegel JS.
PMID: 20818636
Angew Chem Int Ed Engl. 2010 Oct 04;49(41):7519-22. doi: 10.1002/anie.201003762.

No abstract available.

HIV-1 Nef: a multifaceted modulator of T cell receptor signaling.

Cell communication and signaling : CCS

Abraham L, Fackler OT.
PMID: 23227982
Cell Commun Signal. 2012 Dec 10;10(1):39. doi: 10.1186/1478-811X-10-39.

Nef, an accessory protein of the Human Immunodeficiency Virus type 1 (HIV-1), is dispensable for viral replication in cell culture, but promotes virus replication and pathogenesis in the infected host. Acting as protein-interaction adaptor, HIV-1 Nef modulates numerous target...

Base Adducts of â-Ketoenolates. VII. Electron Paramagnetic Resonance Studies of Some Fluxional 1,1,1,5,5,5-Hexafluoro-2,4-pentadionatocopper(II) Complexes.

Inorganic chemistry

Pradilla-Sorzano J, Fackler JP.
PMID: 22463074
Inorg Chem. 1974 Dec 01;13(12):3046. doi: 10.1021/ic50142a602.

No abstract available.

Accurate theoretical beta -decay energy spectrum of the tritium molecule and its neutrino mass dependence.

Physical review letters

Fackler O, Jeziorski B, Kolos W, Monkhorst HJ, Szalewicz K.
PMID: 10031806
Phys Rev Lett. 1985 Sep 23;55(13):1388-1391. doi: 10.1103/PhysRevLett.55.1388.

No abstract available.

Molecular effects in tritium beta decay. IV. Effect of crystal excitations on neutrino mass determination.

Physical review. A, General physics

Fackler O, Jeziorski B, Kolos W, Monkhorst HJ, Rychlewski J, Szalewicz K.
PMID: 9899932
Phys Rev A Gen Phys. 1988 Apr 01;37(7):2297-2303. doi: 10.1103/physreva.37.2297.

No abstract available.

Showing 1 to 12 of 114 entries