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Showing 1 to 12 of 65 entries
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Performance of automated scoring of ER, PR, HER2, CK5/6 and EGFR in breast cancer tissue microarrays in the Breast Cancer Association Consortium.

The journal of pathology. Clinical research

Howat WJ, Blows FM, Provenzano E, Brook MN, Morris L, Gazinska P, Johnson N, McDuffus LA, Miller J, Sawyer EJ, Pinder S, van Deurzen CH, Jones L, Sironen R, Visscher D, Caldas C, Daley F, Coulson P, Broeks A, Sanders J, Wesseling J, Nevanlinna H, Fagerholm R, Blomqvist C, Heikkilä P, Ali HR, Dawson SJ, Figueroa J, Lissowska J, Brinton L, Mannermaa A, Kataja V, Kosma VM, Cox A, Brock IW, Cross SS, Reed MW, Couch FJ, Olson JE, Devillee P, Mesker WE, Seyaneve CM, Hollestelle A, Benitez J, Perez JI, Menéndez P, Bolla MK, Easton DF, Schmidt MK, Pharoah PD, Sherman ME, García-Closas M.
PMID: 27499890
J Pathol Clin Res. 2014 Dec 04;1(1):18-32. doi: 10.1002/cjp2.3. eCollection 2015 Jan.

Breast cancer risk factors and clinical outcomes vary by tumour marker expression. However, individual studies often lack the power required to assess these relationships, and large-scale analyses are limited by the need for high throughput, standardized scoring methods. To...

Bacteremia with Aerococcus sanguinicola: Case Series with Characterization of Virulence Properties.

Open forum infectious diseases

Senneby E, Eriksson B, Fagerholm E, Rasmussen M.
PMID: 25734098
Open Forum Infect Dis. 2014 May 23;1(1):ofu025. doi: 10.1093/ofid/ofu025. eCollection 2014 Mar.

BACKGROUND: Since Aerococcus sanguinicola was designated as a species in 2001, only a few cases of bacteremia have been reported. The aim with this study was to describe the clinical presentation of A sanguinicola bacteremia and to determine the...

Calcium binding and concomitant changes in the structure and heat stability of calprotectin (L1 protein).

Clinical molecular pathology

Naess-Andresen CF, Egelandsdal B, Fagerhol MK.
PMID: 16696022
Clin Mol Pathol. 1995 Oct;48(5):M278-84. doi: 10.1136/mp.48.5.m278.

Aim-To obtain further data on the structure and conformation of calprotectin, a prominent leucocyte protein found in many species.Methods-The binding of Ca(2+) to calprotectin was studied by means of equilibrium dialysis using (45)Ca as tracer. The thermal stability and...

Focused Assessment with Sonography in Trauma and Abdominal Computed Tomography Utilization in Adult Trauma Patients: Trends over the Last Decade.

Emergency medicine international

Sheng AY, Dalziel P, Liteplo AS, Fagenholz P, Noble VE.
PMID: 24073336
Emerg Med Int. 2013;2013:678380. doi: 10.1155/2013/678380. Epub 2013 Aug 29.

Objective. We sought to describe the trend in abdominal CT use in adult trauma patients after a point-of-care emergency ultrasound program was introduced. We hypothesized that abdominal CT use would decrease as FAST use increased. Methods. We performed a...

Corrigendum to "Short peptide analogs as alternatives to collagen in pro-regenerative corneal implants" [Acta Biomater. 69 (2018) 120-130].

Acta biomaterialia

Jangamreddy JR, Haagdorens MKC, Islam MM, Lewis P, Samanta A, Fagerholm P, Liszka A, Ljunggren MK, Buznyk O, Alarcon EI, Zakaria N, Meek KM, Griffith M.
PMID: 30709699
Acta Biomater. 2019 Apr 01;88:556-557. doi: 10.1016/j.actbio.2019.01.046. Epub 2019 Jan 29.

No abstract available.

Biomaterials-enabled cornea regeneration in patients at high risk for rejection of donor tissue transplantation.

NPJ Regenerative medicine

Islam MM, Buznyk O, Reddy JC, Pasyechnikova N, Alarcon EI, Hayes S, Lewis P, Fagerholm P, He C, Iakymenko S, Liu W, Meek KM, Sangwan VS, Griffith M.
PMID: 29423280
NPJ Regen Med. 2018 Jan 31;3:2. doi: 10.1038/s41536-017-0038-8. eCollection 2018.

The severe worldwide shortage of donor organs, and severe pathologies placing patients at high risk for rejecting conventional cornea transplantation, have left many corneal blind patients untreated. Following successful pre-clinical evaluation in mini-pigs, we tested a biomaterials-enabled pro-regeneration strategy...

Corrigendum to "Short peptide analogs as alternatives to collagen in pro-regenerative corneal implants" [Acta Biomaterialia 69 (2018) 120-130].

Acta biomaterialia

Jangamreddy JR, Haagdorens MKC, Islam MM, Lewis P, Samanta A, Fagerholm P, Liszka A, Ljunggren MK, Buznyk O, Alarcon EI, Zakaria N, Meek KM, Griffith M.
PMID: 30385236
Acta Biomater. 2018 Nov;81:330-331. doi: 10.1016/j.actbio.2018.10.009. Epub 2018 Oct 29.

No abstract available.

Nampt controls skeletal muscle development by maintaining Ca.

Molecular metabolism

Basse AL, Agerholm M, Farup J, Dalbram E, Nielsen J, Ørtenblad N, Altıntaş A, Ehrlich AM, Krag T, Bruzzone S, Dall M, de Guia RM, Jensen JB, Møller AB, Karlsen A, Kjær M, Barrès R, Vissing J, Larsen S, Jessen N, Treebak JT.
PMID: 34119711
Mol Metab. 2021 Nov;53:101271. doi: 10.1016/j.molmet.2021.101271. Epub 2021 Jun 11.

OBJECTIVE: NADMETHODS: To determine the role of Nampt in muscle development and function, we generated skeletal muscle-specific Nampt KO (SMNKO) mice. We performed a comprehensive phenotypic characterization of the SMNKO mice, including metabolic measurements, histological examinations, and RNA sequencing...

Parcels and particles: Markov blankets in the brain.

Network neuroscience (Cambridge, Mass.)

Friston KJ, Fagerholm ED, Zarghami TS, Parr T, Hipólito I, Magrou L, Razi A.
PMID: 33688613
Netw Neurosci. 2021 Mar 01;5(1):211-251. doi: 10.1162/netn_a_00175. eCollection 2021.

At the inception of human brain mapping, two principles of functional anatomy underwrote most conceptions-and analyses-of distributed brain responses: namely, functional

Type I interferon supports γδ T-cell homeostasis and immunity through direct and indirect receptor signaling in mice.

European journal of immunology

Agerholm R, Kadekar D, Rizk J, Bekiaris V.
PMID: 34624928
Eur J Immunol. 2021 Dec;51(12):3186-3193. doi: 10.1002/eji.202149186. Epub 2021 Nov 01.

Interleukin (IL)-17-producing gamma delta (γδ) T (γδT17) cells are an essential part of innate type 3 immunity against numerous pathogens. At the same time, a large body of evidence from mouse models and human clinical studies suggests that γδT17...

Abdominal Wall Thickness Predicts Surgical Site Infection in Emergency Colon Operations.

The Journal of surgical research

Narueponjirakul N, Breen KA, El Hechi MW, Kongkaewpaisan N, Velmahos G, King D, Fagenholz P, Saillant N, Tabrizi M, Mendoza AE, Kaafarani HMA, Rosenthal MG.
PMID: 34130237
J Surg Res. 2021 Nov;267:37-47. doi: 10.1016/j.jss.2021.04.038. Epub 2021 Jun 12.

BACKGROUND: Body mass index (BMI) does not reliably predict Surgical site infections (SSI). We hypothesize that abdominal wall thickness (AWT) would serve as a better predictor of SSI for patients undergoing emergency colon operations.METHODS: We retrospectively evaluated our Emergency...

Type I interferon supports γδ T-cell homeostasis and immunity through direct and indirect receptor signaling in mice.

European journal of immunology

Agerholm R, Kadekar D, Rizk J, Bekiaris V.
PMID: 34624928
Eur J Immunol. 2021 Dec;51(12):3186-3193. doi: 10.1002/eji.202149186. Epub 2021 Nov 01.

Interleukin (IL)-17-producing gamma delta (γδ) T (γδT17) cells are an essential part of innate type 3 immunity against numerous pathogens. At the same time, a large body of evidence from mouse models and human clinical studies suggests that γδT17...

Showing 1 to 12 of 65 entries