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Showing 1 to 12 of 19 entries
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Meta-analysis of Genome-Wide Association Studies for Extraversion: Findings from the Genetics of Personality Consortium.

Behavior genetics

van den Berg SM, de Moor MH, Verweij KJ, Krueger RF, Luciano M, Arias Vasquez A, Matteson LK, Derringer J, Esko T, Amin N, Gordon SD, Hansell NK, Hart AB, Seppälä I, Huffman JE, Konte B, Lahti J, Lee M, Miller M, Nutile T, Tanaka T, Teumer A, Viktorin A, Wedenoja J, Abdellaoui A, Abecasis GR, Adkins DE, Agrawal A, Allik J, Appel K, Bigdeli TB, Busonero F, Campbell H, Costa PT, Smith GD, Davies G, de Wit H, Ding J, Engelhardt BE, Eriksson JG, Fedko IO, Ferrucci L, Franke B, Giegling I, Grucza R, Hartmann AM, Heath AC, Heinonen K, Henders AK, Homuth G, Hottenga JJ, Iacono WG, Janzing J, Jokela M, Karlsson R, Kemp JP, Kirkpatrick MG, Latvala A, Lehtimäki T, Liewald DC, Madden PA, Magri C, Magnusson PK, Marten J, Maschio A, Mbarek H, Medland SE, Mihailov E, Milaneschi Y, Montgomery GW, Nauck M, Nivard MG, Ouwens KG, Palotie A, Pettersson E, Polasek O, Qian Y, Pulkki-Råback L, Raitakari OT, Realo A, Rose RJ, Ruggiero D, Schmidt CO, Slutske WS, Sorice R, Starr JM, St Pourcain B, Sutin AR, Timpson NJ, Trochet H, Vermeulen S, Vuoksimaa E, Widen E, Wouda J, Wright MJ, Zgaga L, Porteous D, Minelli A, Palmer AA, Rujescu D, Ciullo M, Hayward C, Rudan I, Metspalu A, Kaprio J, Deary IJ, Räikkönen K, Wilson JF, Keltikangas-Järvinen L, Bierut LJ, Hettema JM, Grabe HJ, Penninx BW, van Duijn CM, Evans DM, Schlessinger D, Pedersen NL, Terracciano A, McGue M, Martin NG, Boomsma DI.
PMID: 26362575
Behav Genet. 2016 Mar;46(2):170-82. doi: 10.1007/s10519-015-9735-5. Epub 2015 Sep 11.

Extraversion is a relatively stable and heritable personality trait associated with numerous psychosocial, lifestyle and health outcomes. Despite its substantial heritability, no genetic variants have been detected in previous genome-wide association (GWA) studies, which may be due to relatively...

Author Correction: Heritability estimates for 361 blood metabolites across 40 genome-wide association studies.

Nature communications

Hagenbeek FA, Pool R, van Dongen J, Draisma HM, Jan Hottenga J, Willemsen G, Abdellaoui A, Fedko IO, den Braber A, Visser PJ, de Geus EJCN, Willems van Dijk K, Verhoeven A, Suchiman HE, Beekman M, Slagboom PE, van Duijn CM, Harms AC, Hankemeier T, Bartels M, Nivard MG, Boomsma DI.
PMID: 32235831
Nat Commun. 2020 Mar 31;11(1):1702. doi: 10.1038/s41467-020-15276-y.

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

Thermo-Oxidation of Phytosterol Molecules in Rapeseed Oil during Heating: The Impact of Unsaturation Level of the Oil.

Foods (Basel, Switzerland)

Kmiecik D, Fedko M, Rudzińska M, Siger A, Gramza-Michałowska A, Kobus-Cisowska J.
PMID: 33375349
Foods. 2020 Dec 26;10(1). doi: 10.3390/foods10010050.

Phytosterols are naturally occurring substances in foods of plant origin that have positive effects on the human body. Their consumption can reduce the level of low density lipoprotein (LDL) cholesterol. The presence of unsaturated bonds in their structure leads...

Child health care system in Ukraine.

Turk pediatri arsivi

Loboda A, Smiyan O, Popov S, Petrashenko V, Zaitsev I, Redko O, Zahorodnii M, Kasyan S.
PMID: 32963485
Turk Pediatri Ars. 2020 Sep 01;55:98-104. doi: 10.14744/TurkPediatriArs.2020.82997. eCollection 2020.

The child healthcare system in Ukraine is coordinated and managed at a central level by the Ministry of Health and at a local level by the regional health authorities. The Ministry of Health has executive the power for the...

Exploring the Pursuit of Doctoral Education by Nurses Seeking or Intending to Stay in Faculty Roles.

Journal of professional nursing : official journal of the American Association of Colleges of Nursing

Dreifuerst KT, McNelis AM, Weaver MT, Broome ME, Draucker CB, Fedko AS.
PMID: 27216128
J Prof Nurs. 2016 May-Jun;32(3):202-12. doi: 10.1016/j.profnurs.2016.01.014. Epub 2016 Feb 04.

The purpose of this study was to describe the factors influencing the pursuit and completion of doctoral education by nurses intending to seek or retain faculty roles. Traditionally, doctoral education evolved to focus on the preparation of nurses to...

Neurocognitive outcomes in Malawian children exposed to malaria during pregnancy: An observational birth cohort study.

PLoS medicine

Weckman AM, Conroy AL, Madanitsa M, Gnaneswaran B, McDonald CR, Kalilani-Phiri L, Chandna J, Ali D, Mwapasa V, Khairallah C, Thwai KL, Meshnick SR, Taylor SM, Ter Kuile FO, Kain KC, Gladstone M.
PMID: 34582452
PLoS Med. 2021 Sep 28;18(9):e1003701. doi: 10.1371/journal.pmed.1003701. eCollection 2021 Sep.

BACKGROUND: Annually 125 million pregnancies are at risk of malaria infection. However, the impact of exposure to malaria in pregnancy on neurodevelopment in children is not well understood. We hypothesized that malaria in pregnancy and associated maternal immune activation...

The Angiopoietin-Tie2 axis contributes to placental vascular disruption and adverse birth outcomes in malaria in pregnancy.

EBioMedicine

Tran V, Weckman AM, Crowley VM, Cahill LS, Zhong K, Cabrera A, Elphinstone RE, Pearce V, Madanitsa M, Kalilani-Phiri L, Mwapasa V, Khairallah C, Conroy AL, Ter Kuile FO, Sled JG, Kain KC.
PMID: 34758414
EBioMedicine. 2021 Nov;73:103683. doi: 10.1016/j.ebiom.2021.103683. Epub 2021 Nov 07.

BACKGROUND: Malaria during pregnancy is a major contributor to the global burden of adverse birth outcomes including fetal growth restriction, preterm birth, and fetal loss. Recent evidence supports a role for angiogenic dysregulation and perturbations to placental vascular development...

Artemisinin-Based Combination Therapy Versus Quinine or Other Combinations for Treatment of Uncomplicated Plasmodium falciparum Malaria in the Second and Third Trimester of Pregnancy: A Systematic Review and Meta-Analysis.

Open forum infectious diseases

Burger RJ, van Eijk AM, Bussink M, Hill J, Ter Kuile FO.
PMID: 26788543
Open Forum Infect Dis. 2015 Nov 12;3(1):ofv170. doi: 10.1093/ofid/ofv170. eCollection 2016 Jan.

The World Health Organization recommends artemisinin-based combination therapies (ACTs) for the treatment of uncomplicated falciparum malaria in the second and third trimesters of pregnancy. We conducted a meta-analysis to compare efficacy, safety and tolerability of ACTs versus quinine and...

Heritability and Genome-Wide Association Studies for Hair Color in a Dutch Twin Family Based Sample.

Genes

Lin BD, Mbarek H, Willemsen G, Dolan CV, Fedko IO, Abdellaoui A, de Geus EJ, Boomsma DI, Hottenga JJ.
PMID: 26184321
Genes (Basel). 2015 Jul 13;6(3):559-76. doi: 10.3390/genes6030559.

Hair color is one of the most visible and heritable traits in humans. Here, we estimated heritability by structural equation modeling (N = 20,142), and performed a genome wide association (GWA) analysis (N = 7091) and a GCTA study...

Impact of Maternal HIV Infection and Placental Malaria on the Transplacental Transfer of Influenza Antibodies in Mother-Infant Pairs in Malawi, 2013-2014.

Open forum infectious diseases

Ho A, Mapurisa G, Madanitsa M, Kalilani-Phiri L, Kamiza S, Makanani B, Ter Kuile FO, Buys A, Treurnicht F, Everett D, Mwapasa V, Widdowson MA, Mcmorrow M, Heyderman RS.
PMID: 31660347
Open Forum Infect Dis. 2019 Aug 28;6(10):ofz383. doi: 10.1093/ofid/ofz383. eCollection 2019 Oct.

BACKGROUND: Maternal influenza vaccination protects infants against influenza virus infection. Impaired transplacental transfer of influenza antibodies may reduce this protection.METHODS: We conducted a cross-sectional study of influenza vaccine-naïve pregnant women recruited at delivery from Blantyre (urban, low malaria transmission)...

Solid-state mechanochemical ω-functionalization of poly(ethylene glycol).

Beilstein journal of organic chemistry

Malca MY, Ferko PO, Friščić T, Moores A.
PMID: 29062415
Beilstein J Org Chem. 2017 Sep 18;13:1963-1968. doi: 10.3762/bjoc.13.191. eCollection 2017.

Poly(ethylene glycol) (PEG) is a linear polymer with a wide range of applications in chemical manufacturing, drug development and nanotechnology. PEG derivatives are being increasingly used to covalently modify small molecule and peptide drugs, as well as bioactive nanomaterials...

A randomized controlled trial of folate supplementation when treating malaria in pregnancy with sulfadoxine-pyrimethamine.

PLoS clinical trials

Ouma P, Parise ME, Hamel MJ, Ter Kuile FO, Otieno K, Ayisi JG, Kager PA, Steketee RW, Slutsker L, van Eijk AM.
PMID: 17053829
PLoS Clin Trials. 2006 Oct 20;1(6):e28. doi: 10.1371/journal.pctr.0010028.

OBJECTIVES: Sulfadoxine-pyrimethamine (SP) is an antimalarial drug that acts on the folate metabolism of the malaria parasite. We investigated whether folate (FA) supplementation in a high or a low dose affects the efficacy of SP for the treatment of...

Showing 1 to 12 of 19 entries