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Immunocytochemical Characterization of Alzheimer's Disease Hallmarks in APP/PS1 Transgenic Mice Treated with a New Anti-Amyloid-.

Central Asian journal of global health

Carrera I, Etcheverria I, Li Y, Fernandez-Novoa L, Lombardi V, Vigo C, Palacios HH, Benberin VV, Cacabelos R, Aliev G.
PMID: 29805876
Cent Asian J Glob Health. 2014 Mar 27;2:119. doi: 10.5195/cajgh.2013.119. eCollection 2013.

INTRODUCTION: APP/PS1 double-transgenic mouse models of Alzheimer's disease (AD), which overexpress mutated forms of the gene for the human amyloid precursor protein (APP) and presenilin 1 (PS1), have provided robust neuropathological hallmarks of an AD-like pattern at early ages....

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