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Showing 1 to 12 of 42 entries
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The catalytic activity of the inactive conformation of delta-chymotrypsin.

FEBS letters

Fersht AR.
PMID: 11946933
FEBS Lett. 1973 Feb 01;29(3):283-285. doi: 10.1016/0014-5793(73)80039-0.

No abstract available.

Therapeutic hypothermia in severe hypoxic-ischemic encephalopathy: a cost-effectiveness analysis.

The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians

Packer CH, Hersh AR, Sargent JA, Caughey AB.
PMID: 32156180
J Matern Fetal Neonatal Med. 2020 Mar 10;1-8. doi: 10.1080/14767058.2020.1733519. Epub 2020 Mar 10.

No abstract available.

Straightforward Access to the Nitric Oxide Donor Azasydnone Scaffold by Cascade Reactions of Amines.

Chemistry (Weinheim an der Bergstrasse, Germany)

Zhilin ES, Bystrov DM, Ananyev IV, Fershtat LL, Makhova NN.
PMID: 31508851
Chemistry. 2019 Nov 13;25(63):14284-14289. doi: 10.1002/chem.201903526. Epub 2019 Oct 17.

A novel one-pot cascade method for the assembly of valuable NO-donor azasydnone scaffold has been developed. The construction strategy involves a diazotization/azo coupling/elimination/double rearrangement cascade sequence of readily available amines. The current protocol enables the generation of a diverse...

Folding and binding.

Current opinion in structural biology

Dill KA, Fersht AR.
PMID: 8794135
Curr Opin Struct Biol. 1996 Feb 01;6(1):1-2. doi: 10.1016/s0959-440x(96)80087-x.

No abstract available.

A Budget Impact Analysis of Gene Therapy for Sickle Cell Disease: The Medicaid Perspective.

JAMA pediatrics

DeMartino P, Haag MB, Hersh AR, Caughey AB, Roth JA.
PMID: 33749717
JAMA Pediatr. 2021 Jun 01;175(6):617-623. doi: 10.1001/jamapediatrics.2020.7140.

IMPORTANCE: Hundreds of gene therapies are undergoing clinical testing and are likely to be priced more than $1 million per course of treatment. The association that high prices will have with insurance coverage of gene therapy remains unclear. Gene...

Maternal and infant hospitalization costs associated with maternal pre-pregnancy body mass index in California, 2007-2011.

The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians

Mischkot BF, Hersh AR, Greiner KS, Garg B, Caughey AB.
PMID: 33261530
J Matern Fetal Neonatal Med. 2020 Dec 01;1-10. doi: 10.1080/14767058.2020.1852207. Epub 2020 Dec 01.

BACKGROUND: In the United States, the number of pregnant women who are overweight or obese is increasing. While such individuals are at increased risk of pregnancy complications, data regarding costs associated with pre-pregnancy body mass index (BMI) and maternal...

Recent Advances in the Synthesis and Biomedical Applications of Heterocyclic NO-Donors.

Molecules (Basel, Switzerland)

Fershtat LL, Zhilin ES.
PMID: 34577175
Molecules. 2021 Sep 21;26(18). doi: 10.3390/molecules26185705.

Nitric oxide (NO) is a key signaling molecule that acts in various physiological processes such as cellular metabolism, vasodilation and transmission of nerve impulses. A wide number of vascular diseases as well as various immune and neurodegenerative disorders were...

Cost-effectiveness of influenza vaccination during pregnancy.

The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians

Chaiken SR, Hersh AR, Zimmermann MS, Ameel BM, Layoun VR, Caughey AB.
PMID: 33478281
J Matern Fetal Neonatal Med. 2021 Jan 21;1-17. doi: 10.1080/14767058.2021.1876654. Epub 2021 Jan 21.

OBJECTIVE: To assess the cost-effectiveness of influenza vaccination for all pregnant patients in the United States.METHODS: We designed a cost-effectiveness model to compare outcomes and costs in pregnant patients who received the inactivated, trivalent influenza vaccine to those who...

Retraction. Directed evolution of new catalytic activity using the alpha/beta-barrel scaffold.

Nature

Altamirano MM, Blackburn JM, Aguayo C, Fersht AR.
PMID: 12024219
Nature. 2002 May 23;417(6887):468. doi: 10.1038/417468a.

No abstract available.

Nimodipine in the treatment of dementia.

Drugs of today (Barcelona, Spain : 1998)

Ferszt R, Kanowski S.
PMID: 14988753
Drugs Today (Barc). 1998 Sep;34(9):767-76. doi: 10.1358/dot.1998.34.9.485275.

No abstract available.

Assembly of Tetrazolylfuroxan Organic Salts: Multipurpose Green Energetic Materials with High Enthalpies of Formation and Excellent Detonation Performance.

Chemistry (Weinheim an der Bergstrasse, Germany)

Larin AA, Muravyev NV, Pivkina AN, Suponitsky KY, Ananyev IV, Khakimov DV, Fershtat LL, Makhova NN.
PMID: 30644611
Chemistry. 2019 Mar 15;25(16):4225-4233. doi: 10.1002/chem.201806378. Epub 2019 Feb 19.

A series of highly energetic organic salts comprising a tetrazolylfuroxan anion, explosophoric azido or azo functionalities, and nitrogen-rich cations were synthesized by simple, efficient, and scalable chemical routes. These energetic materials were fully characterized by IR and multinuclear NMR...

How and why to publish in PNAS.

Proceedings of the National Academy of Sciences of the United States of America

Fersht A.
PMID: 16576766
Proc Natl Acad Sci U S A. 2005 May 03;102(18):6241-2. doi: 10.1073/pnas.0502713102.

No abstract available.

Showing 1 to 12 of 42 entries