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Glucose transporter gene expression in rat brain: Pretranslational changes associated with chronic insulin-induced hypoglycemia, fasting, and diabetes.

Molecular and cellular neurosciences

Koranyi L, Bourey RE, James D, Mueckler M, Fiedorek FT, Permutt MA.
PMID: 19912805
Mol Cell Neurosci. 1991 Jun;2(3):244-52. doi: 10.1016/1044-7431(91)90051-o.

Steady-state levels of the major glucose transporter gene (GLUT-1) of the brain were evaluated under three conditions that induced chronic changes in plasma glucose and insulin in adult rats: (i) repeated injection of insulin for 5 days, resulting in...

Development and psychometric evaluation of the Diabetic Gastroparesis Symptom Severity Diary.

Clinical and experimental gastroenterology

Fehnel S, Fiedorek FT, Nelson L, DiBenedetti D, Spence S, Carson RT.
PMID: 30863134
Clin Exp Gastroenterol. 2019 Feb 22;12:93-103. doi: 10.2147/CEG.S184016. eCollection 2019.

BACKGROUND: Diabetic gastroparesis (DG) is defined as delayed gastric emptying with associated gastrointestinal symptoms, without mechanical obstruction. Patient-reported symptoms are critical for diagnosis and evaluation of treatment benefit in DG. The Diabetic Gastroparesis Symptom Severity Diary (DGSSD), a new...

Subcutaneous infusion of exenatide and cardiovascular outcomes in type 2 diabetes: a non-inferiority randomized controlled trial.

Nature medicine

Ruff CT, Baron M, Im K, O'Donoghue ML, Fiedorek FT, Sabatine MS.
PMID: 34873344
Nat Med. 2021 Dec 06; doi: 10.1038/s41591-021-01584-3. Epub 2021 Dec 06.

Glucagon-like peptide 1 receptor agonists (GLP-1RAs) injected periodically have been shown to not increase and, for some members of this class, decrease the risk of cardiovascular events. The cardiovascular safety of delivering a continuous subcutaneous infusion of the GLP-1RA...

Showing 1 to 3 of 3 entries