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Effects of high dose propranolol treatment on dopamine and norepinephrine metabolism in regions of rat brain.

Neuroscience letters

Wiesel FA.
PMID: 19604810
Neurosci Lett. 1976 Mar;2(1):35-8. doi: 10.1016/0304-3940(76)90042-2.

The acute effects of a high dose of d,l-propranolol on the levels of homovanillic acid (HVA), 5-hydroxyindoleacetic acid (5-HIAA) and 4-hydroxy-3-methoxyphenylethylene glycol (HMPG) in rat brain regions were determined by mass fragmentography. A significant elevation of HVA was obtained...

TDP-43 knockdown impairs neurite outgrowth dependent on its target histone deacetylase 6.

Molecular neurodegeneration

Fiesel FC, Schurr C, Weber SS, Kahle PJ.
PMID: 21878116
Mol Neurodegener. 2011 Aug 30;6:64. doi: 10.1186/1750-1326-6-64.

BACKGROUND: Trans-activation response element (TAR) DNA binding protein of 43kDa (TDP-43) is causally related to the neurodegenerative diseases frontotemporal dementia and amyotrophic lateral sclerosis being the hallmark protein in the disease-characteristic neuropathological lesions and via genetic linkage. Histone deacetylase...

Honoring our helpers.

Journal of radiology case reports

Talanow R, Giesel F.
PMID: 22470688
J Radiol Case Rep. 2010;4(1):1-2. doi: 10.3941/jrcr.v4i1.404. Epub 2010 Jan 01.

This special issue of the Journal of Radiology Case Reports honors the reviewers who donated their time and expertise throughout the year 2009 to the high quality and success of this journal.

Honoring our helpers.

Journal of radiology case reports

Talanow R, Giesel F.
PMID: 22470609
J Radiol Case Rep. 2008;2(6):1-2. doi: 10.3941/jrcr.v2i6.125. Epub 2008 Dec 01.

This special issue of the Journal of Radiology Case Reports honors the reviewers who donated their time and expertise to the high quality and success of this journal.

High fibroblast-activation-protein expression in castration-resistant prostate cancer supports the use of FAPI-molecular theranostics.

European journal of nuclear medicine and molecular imaging

Kesch C, Yirga L, Dendl K, Handke A, Darr C, Krafft U, Radtke JP, Tschirdewahn S, Szarvas T, Fazli L, Gleave M, Giesel FL, Haberkorn U, Hadaschik B.
PMID: 34226953
Eur J Nucl Med Mol Imaging. 2021 Dec;49(1):385-389. doi: 10.1007/s00259-021-05423-y. Epub 2021 Jul 05.

PURPOSE: To evaluate fibroblast-activation-protein (FAP) expression in different clinical stages of prostate cancer (PC) with regards to utility of [METHODS: Tissue microarrays (TMAs) were constructed from prostatic tissue from 94 patients at different stages of PC (primary PC, patients...

One-pot and one-step automated radio-synthesis of [.

EJNMMI radiopharmacy and chemistry

Naka S, Watabe T, Lindner T, Cardinale J, Kurimoto K, Moore M, Tatsumi M, Mori Y, Shimosegawa E, Valla F, Kato H, Giesel FL.
PMID: 34420105
EJNMMI Radiopharm Chem. 2021 Aug 21;6(1):28. doi: 10.1186/s41181-021-00142-z.

BACKGROUND: Fibroblast activation protein (FAP) is overexpressed in the stroma of many types of cancer. [RESULTS: Radiosynthesis of [CONCLUSIONS: We established a one-pot one-step automated synthesis method using a CFN-MPS200 synthesizer that provided high radioactivity and stable radiochemical purity...

Strengths and Weaknesses of Non-enhanced and Contrast-enhanced Cadaver Computed Tomography Scans in the Teaching of Gross Anatomy in an Integrated Curriculum.

Anatomical sciences education

Paech D, Klopries K, Nawrotzki R, Schlemmer HP, Giesel FL, Kirsch J, Schultz JH, Kuner T, Doll S.
PMID: 33170986
Anat Sci Educ. 2020 Nov 10; doi: 10.1002/ase.2034. Epub 2020 Nov 10.

Cadaver-specific postmortem computed tomography (PMCT) has become an integral part in anatomy teaching at several universities. Recently, the feasibility of contrast-enhanced (CE)-PMCT has been demonstrated. The purpose of this study was to identify particular strengths and weaknesses of both...

Prostate-specific Membrane Antigen Imaging and Theranostics Impact Patient Outcomes.

European urology focus

Hadaschik BA, Giesel FL, Chi K.
PMID: 32972898
Eur Urol Focus. 2021 Mar;7(2):229-230. doi: 10.1016/j.euf.2020.09.005. Epub 2020 Sep 21.

Improved imaging has consistently led to refinements in clinical care and outcomes. Prostate-specific membrane antigen (PSMA) positron emission tomography/computed tomography is no exception and has emerged as a critical tool for more accurate staging of prostate cancer. PSMA radioligand...

Mitophagy alterations in Alzheimer's disease are associated with granulovacuolar degeneration and early tau pathology.

Alzheimer's & dementia : the journal of the Alzheimer's Association

Hou X, Watzlawik JO, Cook C, Liu CC, Kang SS, Lin WL, DeTure M, Heckman MG, Diehl NN, Al-Shaikh FSH, Walton RL, Ross OA, Melrose HL, Ertekin-Taner N, Bu G, Petrucelli L, Fryer JD, Murray ME, Dickson DW, Fiesel FC, Springer W.
PMID: 33090691
Alzheimers Dement. 2020 Oct 08; doi: 10.1002/alz.12198. Epub 2020 Oct 08.

INTRODUCTION: The cytoprotective PTEN-induced kinase 1 (PINK1)-parkin RBR E3 ubiquitin protein ligase (PRKN) pathway selectively labels damaged mitochondria with phosphorylated ubiquitin (pS65-Ub) for their autophagic removal (mitophagy). Because dysfunctions of mitochondria and degradation pathways are early features of Alzheimer's...

Positive Multifocal PSMA PET/CT in a Patient With Prostate Cancer and Follicular Lymphoma.

Clinical nuclear medicine

Dendl K, Merkel A, Kratochwil C, Choyke PL, Kleist C, Cardinale J, Haberkorn U, Giesel FL.
PMID: 34319949
Clin Nucl Med. 2022 Jan 01;47(1):e47-e48. doi: 10.1097/RLU.0000000000003828.

ABSTRACT: Prostate-specific membrane antigen (PSMA) PET/CT is a highly reliable nuclear tracer for diagnostic imaging of prostate cancer. However, PSMA is also expressed by some nonprostatic tissues such as benign tumors, inflammatory processes, and malignant neoplasms. This case presents...

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European journal of nuclear medicine and molecular imaging

Conen P, Pennetta F, Dendl K, Hertel F, Vogg A, Haberkorn U, Giesel FL, Mottaghy FM.
PMID: 34988624
Eur J Nucl Med Mol Imaging. 2022 Jan 06; doi: 10.1007/s00259-021-05660-1. Epub 2022 Jan 06.

PURPOSE: Kidney fibrosis leads to a progressive reduction in kidney function ultimately resulting in kidney failure. Diagnostic tools to detect kidney fibrosis are all invasive in nature requiring kidney biopsies with subsequent histological validation. In this retrospective study, the...

Correction to: Perfusion MRI in CNS disease: current concepts.

Neuroradiology

Essig M, Giesel F, Le-Huu M, Stieltjes B, von Tengg-Kobligk H, Weber MA.
PMID: 32215681
Neuroradiology. 2020 Jun;62(6):763. doi: 10.1007/s00234-020-02399-8.

The above article was published with one author name being incorrect. The published paper states "H. von Tengg", whereas it should be "H. von Tengg-Kobligk". The author name has been corrected above.

Showing 1 to 12 of 75 entries