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Showing 1 to 7 of 7 entries
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The immunodeficiency-cancer registry is renewed.

Immunology today

Filopovich AH, Stoker V.
PMID: 25290748
Immunol Today. 1984 Nov;5(11):309. doi: 10.1016/0167-5699(84)90117-8.

No abstract available.

High lymphoid enhancer-binding factor-1 expression is associated with disease progression and poor prognosis in chronic lymphocytic leukemia.

Hematology reports

Erdfelder F, Hertweck M, Filipovich A, Uhrmacher S, Kreuzer KA.
PMID: 22184516
Hematol Rep. 2010 Jan 26;2(1):e3. doi: 10.4081/hr.2010.e3. Epub 2010 May 06.

We determined lymphoid enhancer-binding factor-1 (LEF1) mRNA expression in 112 chronic lymphocytic leukemia (CLL) samples and assessed correlations with the prognostic markers ZAP70 and CD38, Binet stages, the percentage of lymphocytes in the peripheral blood, and fibromodulin (FMOD) transcripts....

Erratum to "Bortezomib for Refractory Autoimmunity in Pediatrics" [Biol Blood Marrow Transplant 2014;20(10):1654-1659].

Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation

Khandelwal P, Davies SM, Grimley MS, Jordan MB, Curtis BR, Jodele S, Marsh R, Filipovich AH.
PMID: 27179942
Biol Blood Marrow Transplant. 2016 Jun;22(6):1147. doi: 10.1016/j.bbmt.2015.11.014. Epub 2015 Nov 28.

No abstract available.

Elevated Granzyme B in Cytotoxic Lymphocytes is a Signature of Immune Activation in Hemophagocytic Lymphohistiocytosis.

Frontiers in immunology

Mellor-Heineke S, Villanueva J, Jordan MB, Marsh R, Zhang K, Bleesing JJ, Filipovich AH, Risma KA.
PMID: 23524976
Front Immunol. 2013 Mar 22;4:72. doi: 10.3389/fimmu.2013.00072. eCollection 2013.

Patients with hemophagocytic lymphohistiocytosis (HLH) exhibit immune hyper-activation as a consequence of genetic defects in secretory granule proteins of cytotoxic T lymphocytes (CTL) and natural killer (NK) cells. Murine models of HLH demonstrate significant activation of CTL as central...

Clinical Flow Cytometric Screening of SAP and XIAP Expression Accurately Identifies Patients with SH2D1A and XIAP/BIRC4 Mutations.

Cytometry. Part B, Clinical cytometry

Gifford CE, Weingartner E, Villanueva J, Johnson J, Zhang K, Filipovich AH, Bleesing JJ, Marsh RA.
PMID: 26305518
Cytometry B Clin Cytom. 2014 Feb 07; doi: 10.1002/cytob.21166. Epub 2014 Feb 07.

INTRODUCTION: X-linked lymphoproliferative disease is caused by mutations in 2 genes, SH2D1A and XIAP/BIRC4. Flow cytometric methods have been developed to detect the gene products, SAP and XIAP. However, there is no literature describing the accuracy of flow cytometric...

B-lymphocyte function in immunodeficiency disease.

Immunology today

Filipovich AH, Kersey JH.
PMID: 25291070
Immunol Today. 1983 Feb;4(2):50-5. doi: 10.1016/0167-5699(83)90111-1.

While B lymphocytes were originally named after their developmental site in the bursa of, Fabricius of chickens, it is currently accepted that bone marrow is the primary site of early events in the differentiation of postnatal B lymphocytes in...

Wiskott-Aldrich syndrome: diagnosis, current management, and emerging treatments.

The application of clinical genetics

Buchbinder D, Nugent DJ, Fillipovich AH.
PMID: 24817816
Appl Clin Genet. 2014 Apr 03;7:55-66. doi: 10.2147/TACG.S58444. eCollection 2014.

Wiskott-Aldrich syndrome (WAS) is a rare X-linked primary immunodeficiency disorder characterized by the triad of eczema, thrombocytopenia, and severe and often recurrent infections. Despite the rarity of this disorder, our understanding of the molecular and cellular pathogenesis of WAS...

Showing 1 to 7 of 7 entries