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Showing 1 to 12 of 42 entries
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Preliminary evidence of endotoxic activity of Bilophila wadsworthia.

Anaerobe

Mosca A, D'Alagni M, Del Prete R, De Michele GP, Summanen PH, Finegold SM, Miragliotta G.
PMID: 16887503
Anaerobe. 1995 Feb;1(1):21-4. doi: 10.1016/s1075-9964(95)80379-3.

In this study we describe two properties of the Gram-negative bacterium Bilophila wadsworthia, namely the ability to clot Limulus lysate and the capacity to induce the production of tissue factor-like procoagulant activity by human mononuclear cells in vitro. Although...

Adherence of Bilophila wadsworthia to cultured human embryonic intestinal cells.

Anaerobe

Gerardo SH, Garcia MM, Wexler HM, Finegold SM.
PMID: 16887620
Anaerobe. 1998 Feb;4(1):19-27. doi: 10.1006/anae.1997.0134.

Adherence of Bilophila wadsworthia to the cultured human embryonic intestinal cell line, Intestine 407 (Int 407), varied among the strains tested from strongly adherent (76-100% cells positive for one or more adherent bacteria) to non- or weakly adherent (0-25%...

Comparison of recovery of anaerobic bacteria using the Anoxomat, anaerobic chamber, and GasPak jar systems.

Anaerobe

Summanen PH, McTeague M, Väisänen ML, Strong CA, Finegold SM.
PMID: 16887656
Anaerobe. 1999 Feb;5(1):5-9. doi: 10.1006/anae.1999.0184.

The Anoxomat system provides an automated evacuation-replacement technique to create an anaerobic or microaerophilic environment in a jar. We evaluated the Anoxomat system for the growth of obligate anaerobes and for the recovery of anaerobic organisms from clinical specimens,...

Taxonomy--General comments and update on taxonomy of Clostridia and Anaerobic cocci.

Anaerobe

Finegold SM, Song Y, Liu C.
PMID: 16887670
Anaerobe. 2002 Oct;8(5):283-5. doi: 10.1006/anae.2002.0436.

Since such things as sites of normal carriage, type and severity of infections produced, and antimicrobial susceptibility patterns may vary according to the particular species involved, accurate taxonomy for differentiation of species is important. For example, reclassification of the...

Fatal septicemia due to Clostridium hathewayi and Campylobacter hominis.

Anaerobe

Linscott AJ, Flamholtz RB, Shukla D, Song Y, Liu C, Finegold SM.
PMID: 16701538
Anaerobe. 2005 Feb-Apr;11(1):97-8. doi: 10.1016/j.anaerobe.2004.10.002. Epub 2004 Nov 30.

Clostridium hathewayi and Campylobacter hominis have not been previously reported in infection. We report a fatal case of septicemia, massive intravascular hemolysis, shock, and disseminated intravascular coagulation; both of these organisms were recovered on blood culture, although it seems...

Is the UK public ready for genetic medicine?.

Personalized medicine

Finegold P, Mathieson K, Holmes L, Boon M, Cottle M, Donnai D, Middleton-Price H.
PMID: 29783399
Per Med. 2008 Jan;5(1):65-76. doi: 10.2217/17410541.5.1.65.

While discussion about the potential for personalized medicine persists, in the UK embedding pharmacogenetics in mainstream clinical practice will also depend on high levels of confidence and trust of citizens in the motives of stakeholders. The role of Government,...

Nowgen, A Center for Genetics in Healthcare.

Personalized medicine

Middleton-Price H, Finegold P, Talks Z, Donnai D.
PMID: 29783442
Per Med. 2008 Sep;5(5):435-439. doi: 10.2217/17410541.5.5.435.

It is now widely agreed that genetics is set to play a major role in healthcare; 'personalized' medicine, new approaches for treating cancer, and stem cell therapies are typical of the exciting areas of development, whilst large-scale epidemiological studies...

Problem-solving, Adherence to Lifestyle Goals, and Weight Loss Among Individuals Participating in a Weight Loss Study.

International journal of behavioral medicine

Yu Y, Sereika SM, Finegold DN, Burke LE.
PMID: 32681361
Int J Behav Med. 2021 Jun;28(3):328-336. doi: 10.1007/s12529-020-09922-4.

BACKGROUND: The role of problem-solving is not well understood in behavioral weight loss interventions. In a 12-month behavioral weight loss study, we examined whether problem-solving changed over time and the relationships between problem-solving and changes in adherence to calorie,...

Intrahepatic Cholestasis, Refractory Epilepsy, Skeletal Dysplasia, Endocrine Failure, and Dysmorphic Features in a Child With a Monoallelic 2q24-32.2 Deletion Encompassing ABCB11.

Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society

Starosta RT, Granadillo JL, Patel KR, Finegold MJ, Stoll J, Kulkarni S.
PMID: 34428094
Pediatr Dev Pathol. 2021 Aug 24;10935266211036084. doi: 10.1177/10935266211036084. Epub 2021 Aug 24.

We report a newborn who presented with multiple limb and facial anomalies, endocrine disorders, and progressively worsening low-GGT cholestasis. A liver biopsy revealed hepatocellular cholestasis with giant cell transformation. Immunohistochemical staining revealed complete absence of BSEP protein compared to...

Small Cell Undifferentiated Histology Does Not Adversely Affect Outcome in Hepatoblastoma: A Report From the Children's Oncology Group (COG) AHEP0731 Study Committee.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Trobaugh-Lotrario A, Katzenstein HM, Ranganathan S, Lopez-Terrada D, Krailo MD, Piao J, Chung N, Randazzo J, Malogolowkin MH, Furman WL, McCarville EB, Towbin AJ, Tiao GM, Dunn SP, Langham MR, McGahren ED, Feusner J, Rodriguez-Galindo C, Meyers RL, O'Neill AF, Finegold MJ.
PMID: 34874751
J Clin Oncol. 2021 Dec 07;JCO2100803. doi: 10.1200/JCO.21.00803. Epub 2021 Dec 07.

PURPOSE: Small cell undifferentiated (SCU) histology in hepatoblastoma (HB) tumors has historically been associated with a poor prognosis. Tumors from patients enrolled on Children's Oncology Group (COG) study AHEP0731 underwent institutional and central pathologic review for identification of SCU...

Progressive familial intrahepatic cholestasis - farnesoid X receptor deficiency due to .

World journal of clinical cases

Czubkowski P, Thompson RJ, Jankowska I, Knisely AS, Finegold M, Parsons P, Cielecka-Kuszyk J, Strautnieks S, Pawłowska J, Bull LN.
PMID: 34046462
World J Clin Cases. 2021 May 26;9(15):3631-3636. doi: 10.12998/wjcc.v9.i15.3631.

BACKGROUND: Functioning farnesoid X receptor (FXR; encoded by CASE SUMMARY: A boy had severe neonatal cholestasis with moderate hypercholanemia and persistently elevated alpha-fetoprotein. Despite medical treatment, coagulopathy was uncontrollable, prompting liver transplantation at age 8 mo with incidental splenectomy....

Composition and thermal properties of membrane lipids in cryptoendolithic lichen microbiota from antarctica.

Applied and environmental microbiology

Finegold L, Singer MA, Federle TW, Vestal JR.
PMID: 16348165
Appl Environ Microbiol. 1990 Apr;56(4):1191-4. doi: 10.1128/aem.56.4.1191-1194.1990.

In Antarctica there exists a cryptoendolithic microbiota which survives extremely low temperatures. Fatty acid analysis of the membrane phospholipids of this microbial community showed a predominance of polyunsaturated fatty acids. Artificial membranes made from the purified community phospholipids remained...

Showing 1 to 12 of 42 entries