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Showing 1 to 12 of 99 entries
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The prognostic reliability of the Glasgow coma score in traumatic brain injuries: evaluation of MRI data.

European journal of trauma and emergency surgery : official publication of the European Trauma Society

Woischneck D, Firsching R, Schmitz B, Kapapa T.
PMID: 26814926
Eur J Trauma Emerg Surg. 2013 Feb;39(1):79-86. doi: 10.1007/s00068-012-0240-8. Epub 2012 Dec 28.

PURPOSE: To clarify the predictive power of the Glasgow coma score (GCS) after traumatic brain injury (TBI) and in the context of brain stem lesions.METHODS: In 143 patients who had suffered severe TBI, the GCS was correlated to brain...

Disordered eating behaviors in university students in Hanoi, Vietnam.

Journal of eating disorders

Ko N, Tam DM, Viet NK, Scheib P, Wirsching M, Zeeck A.
PMID: 25908976
J Eat Disord. 2015 Apr 01;3:18. doi: 10.1186/s40337-015-0054-2. eCollection 2015.

BACKGROUND: The aim of the study was to examine disordered eating behaviors in university students in Vietnam.METHODS: A total of 244 female university students participated, and 203 data could be analyzed. The Body Mass Index, the SCOFF screening questionnaire...

100th anniversary of the Fourth International Congress of Thalassotherapy in Opatija.

Acta medico-historica adriatica : AMHA

Fischinger A, Fischinger D, Fischinger J, Skrobonja A.
PMID: 20102247
Acta Med Hist Adriat. 2008;6(2):261-76.

The authors of the text have been particularly interested into the organization, the procedure,the accompanying activities as well as the themes covered at 4th International Congress of Thalassotherapy in Opatija in 1908. The Congress was organised by the then...

13C/15N distance determination by CPMAS NMR in uniformly 13C labeled molecules.

Magnetic resonance in chemistry : MRC

Hologne M, Raya J, Hirschinger J.
PMID: 16358305
Magn Reson Chem. 2006 Feb;44(2):174-7. doi: 10.1002/mrc.1744.

The REDOR and CPMAS techniques are applied for measuring 13C-15N dipolar coupling constants in glycine. It is shown that the selective CP or SPECIFIC CP technique removes the coherent evolution of the spin system under homonuclear 13C-13C J couplings....

Results of a psychosomatic training program in China, Vietnam and Laos: successful cross-cultural transfer of a postgraduate training program for medical doctors.

BioPsychoSocial medicine

Fritzsche K, Scheib P, Ko N, Wirsching M, Kuhnert A, Hick J, Schüßler G, Wu W, Yuan S, Cat NH, Vongphrachanh S, Linh NT, Viet NK.
PMID: 22929520
Biopsychosoc Med. 2012 Aug 29;6(1):17. doi: 10.1186/1751-0759-6-17.

BACKGROUND: With the "ASIA-LINK" program, the European Community has supported the development and implementation of a curriculum of postgraduate psychosomatic training for medical doctors in China, Vietnam and Laos. Currently, these three countries are undergoing great social, economic and...

Treatment with low-dose tacrolimus inhibits bleeding complications in a patient with hereditary hemorrhagic telangiectasia and pulmonary arterial hypertension.

Pulmonary circulation

Sommer N, Droege F, Gamen KE, Geisthoff U, Gall H, Tello K, Richter MJ, Deubner LM, Schmiedel R, Hecker M, Spiekerkoetter E, Wirsching K, Seeger W, Ghofrani HA, Pullamsetti S.
PMID: 30260738
Pulm Circ. 2019 Apr-Jun;9(2):2045894018805406. doi: 10.1177/2045894018805406. Epub 2018 Sep 27.

Pulmonary arterial hypertension (PAH) can be found in patients suffering from a loss-of-function mutation of the gene encoding for the activin receptor-like kinase 1 (ALK-1), a bone morphogenetic protein (BMP) type 1 receptor. Interestingly, ALK-1 mutations also lead to...

Influence of Surface Processing on the Biocompatibility of Titanium.

Materials (Basel, Switzerland)

Wirsching K, Lehle K, Jacob P, Gleich O, Strutz J, Kwok P.
PMID: 28824139
Materials (Basel). 2011 Jul 06;4(7):1238-1248. doi: 10.3390/ma4071238.

Surface conditioning of titanium middle ear implants results in an improved biocompatibility, which can be characterized by the properties of fibroblasts cultured on conditioned surfaces. Titanium has been established as a favorable biomaterial in ossicular chain reconstruction. The epithelization...

Cerebral Contusion: An Investigation of Etiology, Risk Factors, Related Diagnoses, and the Surgical Management at a Major Government Hospital in Cambodia.

Asian journal of neurosurgery

Hilmer LV, Park KB, Vycheth I, Wirsching M.
PMID: 29492116
Asian J Neurosurg. 2018 Jan-Mar;13(1):23-30. doi: 10.4103/ajns.AJNS_342_16.

INTRODUCTION: Cerebral contusions are a common type of injury among the Cambodian population, mostly due to road traffic accidents. This article aims to assess various aspects around brain contusion focusing on the condition at admission, residing province, mechanism and...

Sensitivity enhancement by multiple-contact cross-polarization under magic-angle spinning.

Journal of magnetic resonance (San Diego, Calif. : 1997)

Raya J, Hirschinger J.
PMID: 28662486
J Magn Reson. 2017 Aug;281:253-271. doi: 10.1016/j.jmr.2017.06.011. Epub 2017 Jun 16.

Multiple-contact cross-polarization (MC-CP) is applied to powder samples of ferrocene and l-alanine under magic-angle spinning (MAS) conditions. The method is described analytically through the density matrix formalism. The combination of a two-step memory function approach and the Anderson-Weiss approximation...

Vaccination with SARS-CoV-2 Spike Protein and AS03 Adjuvant Induces Rapid Anamnestic Antibodies in the Lung and Protects Against Virus Challenge in Nonhuman Primates.

bioRxiv : the preprint server for biology

Francica JR, Flynn BJ, Foulds KE, Noe AT, Werner AP, Moore IN, Gagne M, Johnston TS, Tucker C, Davis RL, Flach B, O'Connell S, Andrew SF, Lamb E, Flebbe DR, Nurmukhambetova ST, Donaldson MM, Todd JM, Zhu AL, Atyeo C, Fischinger S, Gorman MJ, Shin S, Edara VV, Floyd K, Lai L, Tylor A, McCarthy E, Lecouturier V, Ruiz S, Berry C, Tibbitts T, Andersen H, Cook A, Dodson A, Pessaint L, Ry AV, Koutsoukos M, Gutzeit C, Teng IT, Zhou T, Li D, Haynes BF, Kwong PD, McDermott A, Lewis MG, Fu TM, Chicz R, van der Most R, Corbett KS, Suthar MS, Alter G, Roederer M, Sullivan NJ, Douek DC, Graham BS, Casimiro D, Seder RA.
PMID: 33688652
bioRxiv. 2021 Mar 02; doi: 10.1101/2021.03.02.433390.

Adjuvanted soluble protein vaccines have been used extensively in humans for protection against various viral infections based on their robust induction of antibody responses. Here, soluble prefusion-stabilized spike trimers (preS dTM) from the severe acute respiratory syndrome coronavirus (SARS-CoV-2)...

Pharmacological targeting of host chaperones protects from pertussis toxin in vitro and in vivo.

Scientific reports

Ernst K, Mittler AK, Winkelmann V, Kling C, Eberhardt N, Anastasia A, Sonnabend M, Lochbaum R, Wirsching J, Sakari M, Pulliainen AT, Skerry C, Carbonetti NH, Frick M, Barth H.
PMID: 33686161
Sci Rep. 2021 Mar 08;11(1):5429. doi: 10.1038/s41598-021-84817-2.

Whooping cough is caused by Bordetella pertussis that releases pertussis toxin (PT) which comprises enzyme A-subunit PTS1 and binding/transport B-subunit. After receptor-mediated endocytosis, PT reaches the endoplasmic reticulum from where unfolded PTS1 is transported to the cytosol. PTS1 ADP-ribosylates...

Deciphering the Role of Humoral and Cellular Immune Responses in Different COVID-19 Vaccines-A Comparison of Vaccine Candidate Genes in Roborovski Dwarf Hamsters.

Viruses

Trimpert J, Herwig S, Stein J, Vladimirova D, Adler JM, Abdelgawad A, Firsching TC, Thoma T, Sehouli J, Osterrieder K, Gruber AD, Sawitzki B, Sander LE, Cichon G.
PMID: 34835096
Viruses. 2021 Nov 16;13(11). doi: 10.3390/v13112290.

With the exception of inactivated vaccines, all SARS-CoV-2 vaccines currently used for clinical application focus on the spike envelope glycoprotein as a virus-specific antigen. Compared to other SARS-CoV-2 genes, mutations in the spike protein gene are more rapidly selected...

Showing 1 to 12 of 99 entries