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Psychotropic drugs as inhibitors of glycerolipid biosynthesis and secretion in primary rat hepatocyte cultures.

Toxicology in vitro : an international journal published in association with BIBRA

Boelsterli UA, Bouis P, Donatsch P.
PMID: 20647077
Toxicol In Vitro. 1987;1(3):127-32. doi: 10.1016/0887-2333(87)90012-9.

Glycerolipid synthesis and secretion in rat hepatocyte monolayer cultures have been studied as possible endpoints in cytotoxicity assays. Ten psychotropic drugs of different structural classes were incubated with the hepatocytes at concentrations ranging from 10(-6)m to 5 x 10(-5)m...

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Boelsterli UA, Bouis P, Donatsch P. Psychotropic drugs as inhibitors of glycerolipid biosynthesis and secretion in primary rat hepatocyte cultures. Toxicol In Vitro. 1987;1(3):127-32doi: 10.1016/0887-2333(87)90012-9.
Boelsterli, U. A., Bouis, P., & Donatsch, P. (1987). Psychotropic drugs as inhibitors of glycerolipid biosynthesis and secretion in primary rat hepatocyte cultures. Toxicology in vitro : an international journal published in association with BIBRA, 1(3), 127-32. https://doi.org/10.1016/0887-2333(87)90012-9
Boelsterli, U A, et al. "Psychotropic drugs as inhibitors of glycerolipid biosynthesis and secretion in primary rat hepatocyte cultures." Toxicology in vitro : an international journal published in association with BIBRA vol. 1,3 (1987): 127-32. doi: https://doi.org/10.1016/0887-2333(87)90012-9
Boelsterli UA, Bouis P, Donatsch P. Psychotropic drugs as inhibitors of glycerolipid biosynthesis and secretion in primary rat hepatocyte cultures. Toxicol In Vitro. 1987;1(3):127-32. doi: 10.1016/0887-2333(87)90012-9. PMID: 20647077.
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Optimization of a Potent, Orally Active S1P1 Agonist Containing a Quinolinone Core.

ACS medicinal chemistry letters

Harrington PE, Croghan MD, Fotsch C, Frohn M, Lanman BA, Pennington LD, Pickrell AJ, Reed AB, Sham KK, Tasker A, Arnett HA, Fiorino M, Lee MR, McElvain M, Morrison HG, Xu H, Xu Y, Zhang X, Wong M, Cee VJ.
PMID: 24900374
ACS Med Chem Lett. 2011 Nov 23;3(1):74-8. doi: 10.1021/ml200252b. eCollection 2012 Jan 12.

The optimization of a series of S1P1 agonists with limited activity against S1P3 is reported. A polar headgroup was used to improve the physicochemical and pharmacokinetic parameters of lead quinolinone 6. When dosed orally at 1 and 3 mg/kg,...

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Harrington PE, Croghan MD, Fotsch C, et al. Optimization of a Potent, Orally Active S1P1 Agonist Containing a Quinolinone Core. ACS Med Chem Lett. 2011;3(1):74-8doi: 10.1021/ml200252b.
Harrington, P. E., Croghan, M. D., Fotsch, C., Frohn, M., Lanman, B. A., Pennington, L. D., Pickrell, A. J., Reed, A. B., Sham, K. K., Tasker, A., Arnett, H. A., Fiorino, M., Lee, M. R., McElvain, M., Morrison, H. G., Xu, H., Xu, Y., Zhang, X., Wong, M., & Cee, V. J. (2012). Optimization of a Potent, Orally Active S1P1 Agonist Containing a Quinolinone Core. ACS medicinal chemistry letters, 3(1), 74-8. https://doi.org/10.1021/ml200252b
Harrington, Paul E, et al. "Optimization of a Potent, Orally Active S1P1 Agonist Containing a Quinolinone Core." ACS medicinal chemistry letters vol. 3,1 (2012): 74-8. doi: https://doi.org/10.1021/ml200252b
Harrington PE, Croghan MD, Fotsch C, Frohn M, Lanman BA, Pennington LD, Pickrell AJ, Reed AB, Sham KK, Tasker A, Arnett HA, Fiorino M, Lee MR, McElvain M, Morrison HG, Xu H, Xu Y, Zhang X, Wong M, Cee VJ. Optimization of a Potent, Orally Active S1P1 Agonist Containing a Quinolinone Core. ACS Med Chem Lett. 2011 Nov 23;3(1):74-8. doi: 10.1021/ml200252b. eCollection 2012 Jan 12. PMID: 24900374; PMCID: PMC4025730.
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[Definition of standards and their execution-two inseparable aspects of quality improvement in nursing].

Osterreichische Krankenpflegezeitschrift

Fonatsch R.
PMID: 7892000
Osterr Krankenpflegez. 1995 Jan;48(1):35-7.

No abstract available.

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Fonatsch R. Festlegen von Standards und deren Auswertung-zwei untrennbare Aspekte bei der Qualitätsverbesserung in der Pflege. [Definition of standards and their execution-two inseparable aspects of quality improvement in nursing]. Osterr Krankenpflegez. 1995;48(1):35-7
Fonatsch, R. (1995). Festlegen von Standards und deren Auswertung-zwei untrennbare Aspekte bei der Qualitätsverbesserung in der Pflege. [Definition of standards and their execution-two inseparable aspects of quality improvement in nursing]. Osterreichische Krankenpflegezeitschrift, 48(1), 35-7.
Fonatsch, R. "Festlegen von Standards und deren Auswertung-zwei untrennbare Aspekte bei der Qualitätsverbesserung in der Pflege." [Definition of standards and their execution-two inseparable aspects of quality improvement in nursing]. Osterreichische Krankenpflegezeitschrift vol. 48,1 (1995): 35-7.
Fonatsch R. Festlegen von Standards und deren Auswertung-zwei untrennbare Aspekte bei der Qualitätsverbesserung in der Pflege. [Definition of standards and their execution-two inseparable aspects of quality improvement in nursing]. Osterr Krankenpflegez. 1995 Jan;48(1):35-7. German. PMID: 7892000.
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A synthetic energy dataset for non-intrusive load monitoring in households.

Scientific data

Klemenjak C, Kovatsch C, Herold M, Elmenreich W.
PMID: 32242026
Sci Data. 2020 Apr 02;7(1):108. doi: 10.1038/s41597-020-0434-6.

Research on smart grid technologies is expected to result in effective climate change mitigation. Non-Intrusive Load Monitoring (NILM) is seen as a key technique for enabling innovative smart-grid services. By breaking down the energy consumption of households and industrial...

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Klemenjak C, Kovatsch C, Herold M, et al. A synthetic energy dataset for non-intrusive load monitoring in households. Sci Data. 2020;7(1):108doi: 10.1038/s41597-020-0434-6.
Klemenjak, C., Kovatsch, C., Herold, M., & Elmenreich, W. (2020). A synthetic energy dataset for non-intrusive load monitoring in households. Scientific data, 7(1), 108. https://doi.org/10.1038/s41597-020-0434-6
Klemenjak, Christoph, et al. "A synthetic energy dataset for non-intrusive load monitoring in households." Scientific data vol. 7,1 (2020): 108. doi: https://doi.org/10.1038/s41597-020-0434-6
Klemenjak C, Kovatsch C, Herold M, Elmenreich W. A synthetic energy dataset for non-intrusive load monitoring in households. Sci Data. 2020 Apr 02;7(1):108. doi: 10.1038/s41597-020-0434-6. PMID: 32242026; PMCID: PMC7118146.
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Characterization and comparison of the microbiomes and resistomes of colostrum from selectively treated dry cows.

Journal of dairy science

Vasquez A, Nydam D, Foditsch C, Warnick L, Wolfe C, Doster E, Morley PS.
PMID: 34763917
J Dairy Sci. 2022 Jan;105(1):637-653. doi: 10.3168/jds.2021-20675. Epub 2021 Nov 09.

Professionals in animal agriculture promote prudent use of antimicrobials to address public and animal health concerns, such as reduction of antimicrobial residues and antimicrobial resistance (AMR) in products. Few studies evaluate the effect of selective dry-cow therapy on preservation...

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Vasquez A, Nydam D, Foditsch C, et al. Characterization and comparison of the microbiomes and resistomes of colostrum from selectively treated dry cows. J Dairy Sci. 2021;105(1):637-653doi: 10.3168/jds.2021-20675.
Vasquez, A., Nydam, D., Foditsch, C., Warnick, L., Wolfe, C., Doster, E., & Morley, P. S. (2022). Characterization and comparison of the microbiomes and resistomes of colostrum from selectively treated dry cows. Journal of dairy science, 105(1), 637-653. https://doi.org/10.3168/jds.2021-20675
Vasquez, Amy, et al. "Characterization and comparison of the microbiomes and resistomes of colostrum from selectively treated dry cows." Journal of dairy science vol. 105,1 (2022): 637-653. doi: https://doi.org/10.3168/jds.2021-20675
Vasquez A, Nydam D, Foditsch C, Warnick L, Wolfe C, Doster E, Morley PS. Characterization and comparison of the microbiomes and resistomes of colostrum from selectively treated dry cows. J Dairy Sci. 2022 Jan;105(1):637-653. doi: 10.3168/jds.2021-20675. Epub 2021 Nov 09. PMID: 34763917.
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4-Methoxy-N-[2-(trifluoromethyl)biphenyl-4-ylcarbamoyl]nicotinamide: A Potent and Selective Agonist of S1P1.

ACS medicinal chemistry letters

Pennington LD, Sham KK, Pickrell AJ, Harrington PE, Frohn MJ, Lanman BA, Reed AB, Croghan MD, Lee MR, Xu H, McElvain M, Xu Y, Zhang X, Fiorino M, Horner M, Morrison HG, Arnett HA, Fotsch C, Wong M, Cee VJ.
PMID: 24900263
ACS Med Chem Lett. 2011 Jul 29;2(10):752-7. doi: 10.1021/ml2001399. eCollection 2011 Oct 13.

The sphingosine-1-phosphate-1 receptor (S1P1) and its endogenous ligand sphingosine-1-phosphate (S1P) cooperatively regulate lymphocyte trafficking from the lymphatic system. Herein, we disclose 4-methoxy-N-[2-(trifluoromethyl)biphenyl-4-ylcarbamoyl]nicotinamide (8), an uncommon example of a synthetic S1P1 agonist lacking a polar headgroup, which is shown to...

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Pennington LD, Sham KK, Pickrell AJ, et al. 4-Methoxy-N-[2-(trifluoromethyl)biphenyl-4-ylcarbamoyl]nicotinamide: A Potent and Selective Agonist of S1P1. ACS Med Chem Lett. 2011;2(10):752-7doi: 10.1021/ml2001399.
Pennington, L. D., Sham, K. K., Pickrell, A. J., Harrington, P. E., Frohn, M. J., Lanman, B. A., Reed, A. B., Croghan, M. D., Lee, M. R., Xu, H., McElvain, M., Xu, Y., Zhang, X., Fiorino, M., Horner, M., Morrison, H. G., Arnett, H. A., Fotsch, C., Wong, M., & Cee, V. J. (2011). 4-Methoxy-N-[2-(trifluoromethyl)biphenyl-4-ylcarbamoyl]nicotinamide: A Potent and Selective Agonist of S1P1. ACS medicinal chemistry letters, 2(10), 752-7. https://doi.org/10.1021/ml2001399
Pennington, Lewis D, et al. "4-Methoxy-N-[2-(trifluoromethyl)biphenyl-4-ylcarbamoyl]nicotinamide: A Potent and Selective Agonist of S1P1." ACS medicinal chemistry letters vol. 2,10 (2011): 752-7. doi: https://doi.org/10.1021/ml2001399
Pennington LD, Sham KK, Pickrell AJ, Harrington PE, Frohn MJ, Lanman BA, Reed AB, Croghan MD, Lee MR, Xu H, McElvain M, Xu Y, Zhang X, Fiorino M, Horner M, Morrison HG, Arnett HA, Fotsch C, Wong M, Cee VJ. 4-Methoxy-N-[2-(trifluoromethyl)biphenyl-4-ylcarbamoyl]nicotinamide: A Potent and Selective Agonist of S1P1. ACS Med Chem Lett. 2011 Jul 29;2(10):752-7. doi: 10.1021/ml2001399. eCollection 2011 Oct 13. PMID: 24900263; PMCID: PMC4018088.
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Donor-substituted diphenylacetylene derivatives act as electron donors and acceptors.

The Journal of organic chemistry

Onitsch C, Rosspeintner A, Angulo G, Griesser M, Kivala M, Frank B, Diederich F, Gescheidt G.
PMID: 21604695
J Org Chem. 2011 Jul 15;76(14):5628-35. doi: 10.1021/jo2005022. Epub 2011 Jun 13.

Despite the predominant electron donor character of p-phenylenediamine, our studies on extended p-phenylenediamine derivatives show that they can not only be chemically oxidized, giving well-known Wurster-type radical cations, but also be chemically reduced, giving radical anions. Making use of...

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Onitsch C, Rosspeintner A, Angulo G, et al. Donor-substituted diphenylacetylene derivatives act as electron donors and acceptors. J Org Chem. 2011;76(14):5628-35doi: 10.1021/jo2005022.
Onitsch, C., Rosspeintner, A., Angulo, G., Griesser, M., Kivala, M., Frank, B., Diederich, F., & Gescheidt, G. (2011). Donor-substituted diphenylacetylene derivatives act as electron donors and acceptors. The Journal of organic chemistry, 76(14), 5628-35. https://doi.org/10.1021/jo2005022
Onitsch, Christine, et al. "Donor-substituted diphenylacetylene derivatives act as electron donors and acceptors." The Journal of organic chemistry vol. 76,14 (2011): 5628-35. doi: https://doi.org/10.1021/jo2005022
Onitsch C, Rosspeintner A, Angulo G, Griesser M, Kivala M, Frank B, Diederich F, Gescheidt G. Donor-substituted diphenylacetylene derivatives act as electron donors and acceptors. J Org Chem. 2011 Jul 15;76(14):5628-35. doi: 10.1021/jo2005022. Epub 2011 Jun 13. PMID: 21604695.
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Photophysics of two prototypical molecular-wire building blocks: solvent-induced conformational dynamics?.

Chemphyschem : a European journal of chemical physics and physical chemistry

Rosspeintner A, Angulo G, Onitsch C, Kivala M, Diederich F, Grampp G, Gescheidt G.
PMID: 20408158
Chemphyschem. 2010 Jun 07;11(8):1700-10. doi: 10.1002/cphc.200901005.

The photophysics of two molecular wire building blocks of different lengths based on p-phenyleneethylene, namely, 1,4-bis[p-(N,N-dimethylamino)phenyl]-1,2-ethyne and 1,4-bis[p-(N,N-dihexylamino)phenylethynyl]benzene, are studied experimentally in a wide range of organic solvents. The band shape and position of the electronic absorption and fluorescence...

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Rosspeintner A, Angulo G, Onitsch C, et al. Photophysics of two prototypical molecular-wire building blocks: solvent-induced conformational dynamics?. Chemphyschem. 2010;11(8):1700-10doi: 10.1002/cphc.200901005.
Rosspeintner, A., Angulo, G., Onitsch, C., Kivala, M., Diederich, F., Grampp, G., & Gescheidt, G. (2010). Photophysics of two prototypical molecular-wire building blocks: solvent-induced conformational dynamics?. Chemphyschem : a European journal of chemical physics and physical chemistry, 11(8), 1700-10. https://doi.org/10.1002/cphc.200901005
Rosspeintner, Arnulf, et al. "Photophysics of two prototypical molecular-wire building blocks: solvent-induced conformational dynamics?." Chemphyschem : a European journal of chemical physics and physical chemistry vol. 11,8 (2010): 1700-10. doi: https://doi.org/10.1002/cphc.200901005
Rosspeintner A, Angulo G, Onitsch C, Kivala M, Diederich F, Grampp G, Gescheidt G. Photophysics of two prototypical molecular-wire building blocks: solvent-induced conformational dynamics?. Chemphyschem. 2010 Jun 07;11(8):1700-10. doi: 10.1002/cphc.200901005. PMID: 20408158.
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Temporal reward discounting in children, adolescents, and emerging adults during an experiential task.

Frontiers in psychology

Scheres A, Tontsch C, Thoeny AL, Sumiya M.
PMID: 25071675
Front Psychol. 2014 Jul 08;5:711. doi: 10.3389/fpsyg.2014.00711. eCollection 2014.

The goal of this study was to examine age effects on the ability/willingness to wait for large rewards in a real temporal reward discounting task from childhood to adulthood. Therefore, a real temporal discounting (TD) task was administered to...

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Scheres A, Tontsch C, Thoeny AL, et al. Temporal reward discounting in children, adolescents, and emerging adults during an experiential task. Front Psychol. 2014;5:711doi: 10.3389/fpsyg.2014.00711.
Scheres, A., Tontsch, C., Thoeny, A. L., & Sumiya, M. (2014). Temporal reward discounting in children, adolescents, and emerging adults during an experiential task. Frontiers in psychology, 5711. https://doi.org/10.3389/fpsyg.2014.00711
Scheres, Anouk, et al. "Temporal reward discounting in children, adolescents, and emerging adults during an experiential task." Frontiers in psychology vol. 5 (2014): 711. doi: https://doi.org/10.3389/fpsyg.2014.00711
Scheres A, Tontsch C, Thoeny AL, Sumiya M. Temporal reward discounting in children, adolescents, and emerging adults during an experiential task. Front Psychol. 2014 Jul 08;5:711. doi: 10.3389/fpsyg.2014.00711. eCollection 2014. PMID: 25071675; PMCID: PMC4085649.
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Synthesis and Evaluation of the Metabolites of AMG 221, a Clinical Candidate for the Treatment of Type 2 Diabetes.

ACS medicinal chemistry letters

Li A, Yuan CC, Chow D, Chen M, Emery MG, Hale C, Zhang X, Subramanian R, St Jean DJ, Komorowski R, Véniant M, Wang M, Fotsch C.
PMID: 24900270
ACS Med Chem Lett. 2011 Sep 13;2(11):824-7. doi: 10.1021/ml2001467. eCollection 2011 Nov 10.

All eight of the major active metabolites of (S)-2-((1S,2S,4R)-bicyclo[2.2.1]heptan-2-ylamino)-5-isopropyl-5-methylthiazol-4(5H)-one (AMG 221, compound 1), an inhibitor of 11β-hydroxysteroid dehydrogenase type 1 that has entered the clinic for the treatment of type 2 diabetes, were synthetically prepared and confirmed by comparison...

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Li A, Yuan CC, Chow D, et al. Synthesis and Evaluation of the Metabolites of AMG 221, a Clinical Candidate for the Treatment of Type 2 Diabetes. ACS Med Chem Lett. 2011;2(11):824-7doi: 10.1021/ml2001467.
Li, A., Yuan, C. C., Chow, D., Chen, M., Emery, M. G., Hale, C., Zhang, X., Subramanian, R., St Jean, D. J., Komorowski, R., Véniant, M., Wang, M., & Fotsch, C. (2011). Synthesis and Evaluation of the Metabolites of AMG 221, a Clinical Candidate for the Treatment of Type 2 Diabetes. ACS medicinal chemistry letters, 2(11), 824-7. https://doi.org/10.1021/ml2001467
Li, Aiwen, et al. "Synthesis and Evaluation of the Metabolites of AMG 221, a Clinical Candidate for the Treatment of Type 2 Diabetes." ACS medicinal chemistry letters vol. 2,11 (2011): 824-7. doi: https://doi.org/10.1021/ml2001467
Li A, Yuan CC, Chow D, Chen M, Emery MG, Hale C, Zhang X, Subramanian R, St Jean DJ, Komorowski R, Véniant M, Wang M, Fotsch C. Synthesis and Evaluation of the Metabolites of AMG 221, a Clinical Candidate for the Treatment of Type 2 Diabetes. ACS Med Chem Lett. 2011 Sep 13;2(11):824-7. doi: 10.1021/ml2001467. eCollection 2011 Nov 10. PMID: 24900270; PMCID: PMC4018091.
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Characterization and comparison of the microbiomes and resistomes of colostrum from selectively treated dry cows.

Journal of dairy science

Vasquez A, Nydam D, Foditsch C, Warnick L, Wolfe C, Doster E, Morley PS.
PMID: 34763917
J Dairy Sci. 2021 Nov 08; doi: 10.3168/jds.2021-20675. Epub 2021 Nov 08.

Professionals in animal agriculture promote prudent use of antimicrobials to address public and animal health concerns, such as reduction of antimicrobial residues and antimicrobial resistance (AMR) in products. Few studies evaluate the effect of selective dry-cow therapy on preservation...

Cite
Vasquez A, Nydam D, Foditsch C, et al. Characterization and comparison of the microbiomes and resistomes of colostrum from selectively treated dry cows. J Dairy Sci. 2021;doi: 10.3168/jds.2021-20675.
Vasquez, A., Nydam, D., Foditsch, C., Warnick, L., Wolfe, C., Doster, E., & Morley, P. S. (2021). Characterization and comparison of the microbiomes and resistomes of colostrum from selectively treated dry cows. Journal of dairy science, . https://doi.org/10.3168/jds.2021-20675
Vasquez, Amy, et al. "Characterization and comparison of the microbiomes and resistomes of colostrum from selectively treated dry cows." Journal of dairy science vol. (2021). doi: https://doi.org/10.3168/jds.2021-20675
Vasquez A, Nydam D, Foditsch C, Warnick L, Wolfe C, Doster E, Morley PS. Characterization and comparison of the microbiomes and resistomes of colostrum from selectively treated dry cows. J Dairy Sci. 2021 Nov 08; doi: 10.3168/jds.2021-20675. Epub 2021 Nov 08. PMID: 34763917.
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Showing 1 to 11 of 11 entries