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Showing 1 to 12 of 41 entries
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Potent and Selective Amidopyrazole Inhibitors of IRAK4 That Are Efficacious in a Rodent Model of Inflammation.

ACS medicinal chemistry letters

McElroy WT, Tan Z, Ho G, Paliwal S, Li G, Seganish WM, Tulshian D, Tata J, Fischmann TO, Sondey C, Bian H, Bober L, Jackson J, Garlisi CG, Devito K, Fossetta J, Lundell D, Niu X.
PMID: 26101573
ACS Med Chem Lett. 2015 May 12;6(6):677-82. doi: 10.1021/acsmedchemlett.5b00106. eCollection 2015 Jun 11.

IRAK4 is a critical upstream kinase in the IL-1R/TLR signaling pathway. Inhibition of IRAK4 is hypothesized to be beneficial in the treatment of autoimmune related disorders. A screening campaign identified a pyrazole class of IRAK4 inhibitors that were determined...

Regulation of DDAH1 as a Potential Therapeutic Target for Treating Cardiovascular Diseases.

Evidence-based complementary and alternative medicine : eCAM

Liu X, Fassett J, Wei Y, Chen Y.
PMID: 23878601
Evid Based Complement Alternat Med. 2013;2013:619207. doi: 10.1155/2013/619207. Epub 2013 Jun 26.

Asymmetric dimethylarginine (ADMA) is an endogenous nitric oxide synthase inhibitor that blocks nitric oxide production, while congestive heart failure is associated with increased plasma and tissue ADMA content. Increased plasma ADMA is a strong and independent predictor of all-cause...

Erratum to: Decreasing the Stigma of Mental Illness Through a Student-Nurse Mentoring Program: A Qualitative Study.

Community mental health journal

Fokuo JK, Goldrick V, Rossetti J, Wahlstrom C, Kundert C, Larson J, Corrigan P.
PMID: 28744753
Community Ment Health J. 2017 Nov;53(8):1007. doi: 10.1007/s10597-017-0151-6.

No abstract available.

Erratum to: Disruption of mindin exacerbates cardiac hypertrophy and fibrosis.

Journal of molecular medicine (Berlin, Germany)

Bian ZY, Wei X, Deng S, Tang QZ, Feng J, Zhang Y, Liu C, Jiang DS, Yan L, Zhang LF, Chen M, Fassett J, Chen Y, He YW, Yang Q, Liu PP, Li H.
PMID: 28856378
J Mol Med (Berl). 2017 Nov;95(11):1251-1253. doi: 10.1007/s00109-017-1588-3.

No abstract available.

DNA Immunoprecipitation (DIP) for the Determination of DNA-Binding Specificity.

CSH protocols

Gossett AJ, Lieb JD.
PMID: 21356788
CSH Protoc. 2008 Mar 01;2008:pdb.prot4972. doi: 10.1101/pdb.prot4972.

INTRODUCTIONKnowledge of the DNA-binding specificity of a transcription factor aids in understanding the function of that factor in the regulation of gene transcription. One popular method of identifying the genomic DNA sites bound by a given protein in vivo...

Bladder Cancer Sample Handling and Reporting: Pathologist's Point of View.

Frontiers in surgery

Mazzucchelli R, Marzioni D, Tossetta G, Pepi L, Montironi R.
PMID: 34926567
Front Surg. 2021 Dec 02;8:754741. doi: 10.3389/fsurg.2021.754741. eCollection 2021.

The aim of this narrative review is to provide adequate information on handling and reporting of the bladder cancer samples to improve the closely collaboration between pathologists and urologists. The main (but not exclusive) research tool used was PubMed...

Academic Performance of Children With Sickle Cell Disease in the United States: A Meta-Analysis.

Frontiers in neurology

Heitzer AM, Hamilton L, Stafford C, Gossett J, Ouellette L, Trpchevska A, King AA, Kang G, Hankins JS.
PMID: 34966350
Front Neurol. 2021 Dec 13;12:786065. doi: 10.3389/fneur.2021.786065. eCollection 2021.

No abstract available.

The Multifaced Actions of Curcumin in Pregnancy Outcome.

Antioxidants (Basel, Switzerland)

Tossetta G, Fantone S, Giannubilo SR, Marzioni D.
PMID: 33477354
Antioxidants (Basel). 2021 Jan 17;10(1). doi: 10.3390/antiox10010126.

Curcumin, also known as diferuloylmethane, is the main polyphenolic substance present in the rhizomes of

Regional movements of satellite-tagged whale sharks .

Ecology and evolution

Andrzejaczek S, Vély M, Jouannet D, Rowat D, Fossette S.
PMID: 33976859
Ecol Evol. 2021 Mar 23;11(9):4920-4934. doi: 10.1002/ece3.7400. eCollection 2021 May.

To gain insight into whale shark (

HTRA family proteins in pregnancy outcome.

Tissue & cell

Fantone S, Giannubilo SR, Marzioni D, Tossetta G.
PMID: 33915357
Tissue Cell. 2021 Oct;72:101549. doi: 10.1016/j.tice.2021.101549. Epub 2021 Apr 20.

HTRA (High temperature requirement protease A) family proteins includes HTRA1 (L56 or PRSS11), HTRA2/Omi, HTRA3 (PRSP) and HTRA4. These are oligomeric serine proteases highly conserved from bacteria to humans and are involved in a variety of biological functions including...

Erratum to: Intradermal injection of a Tat Oyi-based therapeutic HIV vaccine reduces of 1.5 log copies/mL the HIV RNA rebound median and no HIV DNA rebound following cART interruption in a phase I/II randomized controlled clinical trial.

Retrovirology

Loret EP, Darque A, Jouve E, Loret EA, Nicolino-Brunet C, Morange S, Castanier E, Casanova J, Caloustian C, Bornet C, Coussirou J, Boussetta J, Couallier V, Blin O, Dussol B, Ravaux I.
PMID: 27160192
Retrovirology. 2016 May 09;13(1):35. doi: 10.1186/s12977-016-0264-y.

No abstract available.

CD93 a potential player in cytotrophoblast and endothelial cell migration.

Cell and tissue research

Fantone S, Tossetta G, Di Simone N, Tersigni C, Scambia G, Marcheggiani F, Giannubilo SR, Marzioni D.
PMID: 34674045
Cell Tissue Res. 2021 Oct 21; doi: 10.1007/s00441-021-03543-3. Epub 2021 Oct 21.

CD93, also known as complement component C1q receptor, is expressed on the surface of different cellular types such as monocytes, neutrophils, platelets, microglia, and endothelial cells, and it plays a pivotal role in cell proliferation, cell migration, and formation...

Showing 1 to 12 of 41 entries