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Showing 1 to 12 of 121 entries
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An ensemble-based Cox proportional hazards regression framework for predicting survival in metastatic castration-resistant prostate cancer (mCRPC) patients.

F1000Research

Meier R, Graw S, Usset J, Raghavan R, Dai J, Chalise P, Ellis S, Fridley B, Koestler D.
PMID: 28413609
F1000Res. 2016 Nov 16;5:2677. doi: 10.12688/f1000research.8226.1. eCollection 2016.

From March through August 2015, nearly 60 teams from around the world participated in the Prostate Cancer Dream Challenge (PCDC). Participating teams were faced with the task of developing prediction models for patient survival and treatment discontinuation using baseline...

Germline whole exome sequencing and large-scale replication identifies .

Oncotarget

Dicks E, Song H, Ramus SJ, Oudenhove EV, Tyrer JP, Intermaggio MP, Kar S, Harrington P, Bowtell DD, Group AS, Cicek MS, Cunningham JM, Fridley BL, Alsop J, Jimenez-Linan M, Piskorz A, Goranova T, Kent E, Siddiqui N, Paul J, Crawford R, Poblete S, Lele S, Sucheston-Campbell L, Moysich KB, Sieh W, McGuire V, Lester J, Odunsi K, Whittemore AS, Bogdanova N, Dürst M, Hillemanns P, Karlan BY, Gentry-Maharaj A, Menon U, Tischkowitz M, Levine D, Brenton JD, Dörk T, Goode EL, Gayther SA, Pharoah DPP.
PMID: 28881617
Oncotarget. 2017 Mar 03;8(31):50930-50940. doi: 10.18632/oncotarget.15871. eCollection 2017 Aug 01.

We analyzed whole exome sequencing data in germline DNA from 412 high grade serous ovarian cancer (HGSOC) cases from The Cancer Genome Atlas Project and identified 5,517 genes harboring a predicted deleterious germline coding mutation in at least one...

Resource availability dominates and alters the relationship between species diversity and ecosystem productivity in experimental plant communities.

Oecologia

Fridley JD.
PMID: 28547362
Oecologia. 2002 Jul;132(2):271-277. doi: 10.1007/s00442-002-0965-x. Epub 2002 Jul 01.

Experimental evidence that plant species diversity has positive effects on biomass production appears to conflict with correlations of species diversity and standing biomass in natural communities. This may be due to the confounding effects of a third variable, resource...

Clinical validation of genetic variants associated with .

Oncotarget

Fasching PA, Häberle L, Rack B, Li L, Hein A, Ekici AB, Reis A, Lux MP, Cunningham JM, Ruebner M, Jenkins G, Fridley B, Schneeweiss A, Tesch H, Lichtenegger W, Fehm T, Heinrich G, Rezai M, Beckmann MW, Janni W, Weinshilboum RM, Wang L.
PMID: 29100455
Oncotarget. 2017 May 09;8(44):78133-78143. doi: 10.18632/oncotarget.17726. eCollection 2017 Sep 29.

Hematotoxicity is one of the major side effects of chemotherapy. The aim of this study was to examine the association between single nucleotide polymorphisms (SNPs) and hematotoxicity in breast cancer patients in a subset of patients of the SUCCESS...

Knowledge to action for solving complex problems: insights from a review of nine international cases.

Health promotion and chronic disease prevention in Canada : research, policy and practice

Riley BL, Robinson KL, Gamble J, Finegood DT, Sheppard D, Penney TL, Best A.
PMID: 25970804
Health Promot Chronic Dis Prev Can. 2015 May;35(3):47-53. doi: 10.24095/hpcdp.35.3.01.

INTRODUCTION: Solving complex problems such as preventing chronic diseases introduces unique challenges for the creation and application of knowledge, or knowledge to action (KTA). KTA approaches that apply principles of systems thinking are thought to hold promise, but practical...

Reliability of treating asymptomatic traumatic type II dens fractures in patients over age 80: A retrospective series.

Journal of craniovertebral junction & spine

Momin E, Harsh V, Fridley J, Winnegan L, Omeis I.
PMID: 26692693
J Craniovertebr Junction Spine. 2015 Oct-Dec;6(4):166-72. doi: 10.4103/0974-8237.167859.

BACKGROUND: Management of type II odontoid fractures in elderly remains controversial to whether surgical treatment is favored over conservative one. This is a study of geriatric patients with asymptomatic type II dens fractures who after sustaining a fall were...

Evidence that nitric acid increases relative humidity in low-temperature cirrus clouds.

Science (New York, N.Y.)

Gao RS, Popp PJ, Fahey DW, Marcy TP, Herman RL, Weinstock EM, Baumgardner DG, Garrett TJ, Rosenlof KH, Thompson TL, Bui PT, Ridley BA, Wofsy SC, Toon OB, Tolbert MA, Kärcher B, Peter T, Hudson PK, Weinheimer AJ, Heymsfield AJ.
PMID: 14739457
Science. 2004 Jan 23;303(5657):516-20. doi: 10.1126/science.1091255.

In situ measurements of the relative humidity with respect to ice (RHi) and of nitric acid (HNO3) were made in both natural and contrail cirrus clouds in the upper troposphere. At temperatures lower than 202 kelvin, RHi values show...

Comparison of Penalty Functions for Sparse Canonical Correlation Analysis.

Computational statistics & data analysis

Chalise P, Fridley BL.
PMID: 21984855
Comput Stat Data Anal. 2012 Feb 01;56(2):245-254. doi: 10.1016/j.csda.2011.07.012.

Canonical correlation analysis (CCA) is a widely used multivariate method for assessing the association between two sets of variables. However, when the number of variables far exceeds the number of subjects, such in the case of large-scale genomic studies,...

Low-coordinate cobalt(II) terphenyl complexes: precursors to sterically encumbered ketones.

Chemical communications (Cambridge, England)

Gridley BM, Blake AJ, Davis AL, Lewis W, Moxey GJ, Kays DL.
PMID: 22847536
Chem Commun (Camb). 2012 Sep 14;48(71):8910-2. doi: 10.1039/c2cc34525k. Epub 2012 Jul 31.

Cobalt(II) diaryl complexes react with CO to afford Co(2)(CO)(8) and sterically encumbered ketones whose structure varies depending on the nature of the aryl ligands.

Optical-phonon tunneling.

Physical review. B, Condensed matter

Ridley BK.
PMID: 10010904
Phys Rev B Condens Matter. 1994 Jun 15;49(24):17253-17258. doi: 10.1103/physrevb.49.17253.

No abstract available.

Free optical vibrations of an infinite plate of homogeneous isotropic elastic matter.

Physical review. B, Condensed matter

Ridley BK.
PMID: 9998862
Phys Rev B Condens Matter. 1991 Oct 15;44(16):9002-9011. doi: 10.1103/physrevb.44.9002.

No abstract available.

Outcomes of endoscopic discectomy compared with open microdiscectomy and tubular microdiscectomy for lumbar disc herniations: a meta-analysis.

Journal of neurosurgery. Spine

Barber SM, Nakhla J, Konakondla S, Fridley JS, Oyelese AA, Gokaslan ZL, Telfeian AE.
PMID: 31491760
J Neurosurg Spine. 2019 Sep 06;1-14. doi: 10.3171/2019.6.SPINE19532. Epub 2019 Sep 06.

OBJECTIVE: Endoscopic discectomy (ED) has been advocated as a less-invasive alternative to open microdiscectomy (OM) and tubular microdiscectomy (TM) for lumbar disc herniations, with the potential to decrease postoperative pain and shorten recovery times. Large-scale, objective comparisons of outcomes...

Showing 1 to 12 of 121 entries