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Antidiabetic effect of enterolactone in cultured muscle cells and in type 2 diabetic model db/db mice.

Cytotechnology

Zhou F, Furuhashi K, Son MJ, Toyozaki M, Yoshizawa F, Miura Y, Yagasaki K.
PMID: 27000262
Cytotechnology. 2017 Jun;69(3):493-502. doi: 10.1007/s10616-016-9965-2. Epub 2016 Mar 21.

Enterolactone (ENL) is formed by the conversion of dietary precursors like strawberry lignans via the gut microbiota. Urinary concentrations of lignan metabolites are reported to be significantly associated with a lower risk of Type 2 diabetes (T2D). In the...

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Zhou F, Furuhashi K, Son MJ, et al. Antidiabetic effect of enterolactone in cultured muscle cells and in type 2 diabetic model db/db mice. Cytotechnology. 2016;69(3):493-502doi: 10.1007/s10616-016-9965-2.
Zhou, F., Furuhashi, K., Son, M. J., Toyozaki, M., Yoshizawa, F., Miura, Y., & Yagasaki, K. (2017). Antidiabetic effect of enterolactone in cultured muscle cells and in type 2 diabetic model db/db mice. Cytotechnology, 69(3), 493-502. https://doi.org/10.1007/s10616-016-9965-2
Zhou, Fang, et al. "Antidiabetic effect of enterolactone in cultured muscle cells and in type 2 diabetic model db/db mice." Cytotechnology vol. 69,3 (2017): 493-502. doi: https://doi.org/10.1007/s10616-016-9965-2
Zhou F, Furuhashi K, Son MJ, Toyozaki M, Yoshizawa F, Miura Y, Yagasaki K. Antidiabetic effect of enterolactone in cultured muscle cells and in type 2 diabetic model db/db mice. Cytotechnology. 2017 Jun;69(3):493-502. doi: 10.1007/s10616-016-9965-2. Epub 2016 Mar 21. PMID: 27000262; PMCID: PMC5461240.
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Anti-prion activity found in beetle grub hemolymph of .

Biochemistry and biophysics reports

Hamanaka T, Nishizawa K, Sakasegawa Y, Kurahashi H, Oguma A, Teruya K, Doh-Ura K.
PMID: 29124167
Biochem Biophys Rep. 2015 Jul 17;3:32-37. doi: 10.1016/j.bbrep.2015.07.009. eCollection 2015 Sep.

No remedies for prion disease have been established, and the conversion of normal to abnormal prion protein, a key event in prion disease, is still unclear. Here we found that substances in beetle grub hemolymph, after they were browned...

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Hamanaka T, Nishizawa K, Sakasegawa Y, et al. Anti-prion activity found in beetle grub hemolymph of . Biochem Biophys Rep. 2015;3:32-37doi: 10.1016/j.bbrep.2015.07.009.
Hamanaka, T., Nishizawa, K., Sakasegawa, Y., Kurahashi, H., Oguma, A., Teruya, K., & Doh-Ura, K. (2015). Anti-prion activity found in beetle grub hemolymph of . Biochemistry and biophysics reports, 332-37. https://doi.org/10.1016/j.bbrep.2015.07.009
Hamanaka, Taichi, et al. "Anti-prion activity found in beetle grub hemolymph of ." Biochemistry and biophysics reports vol. 3 (2015): 32-37. doi: https://doi.org/10.1016/j.bbrep.2015.07.009
Hamanaka T, Nishizawa K, Sakasegawa Y, Kurahashi H, Oguma A, Teruya K, Doh-Ura K. Anti-prion activity found in beetle grub hemolymph of . Biochem Biophys Rep. 2015 Jul 17;3:32-37. doi: 10.1016/j.bbrep.2015.07.009. eCollection 2015 Sep. PMID: 29124167; PMCID: PMC5668675.
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A case of treatment with voriconazole for chronic progressive pulmonary aspergillosis in a patient receiving tacrolimus for dermatomyositis-associated interstitial lung disease.

Respiratory medicine case reports

Mochizuki E, Furuhashi K, Fujisawa T, Enomoto N, Inui N, Nakamura Y, Kono M, Hamada E, Maekawa M, Suda T.
PMID: 26744690
Respir Med Case Rep. 2015 Nov 03;16:163-5. doi: 10.1016/j.rmcr.2015.10.008. eCollection 2015.

We report a successful treatment with voriconazole (VRCZ) for chronic progressive pulmonary aspergillosis (CPPA) in a patient with dermatomyositis-associated interstitial lung disease (DM-ILD) treated with tacrolimus. A 73-year-old man with DM-ILD, treated with tacrolimus and prednisolone, complained of productive...

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Mochizuki E, Furuhashi K, Fujisawa T, et al. A case of treatment with voriconazole for chronic progressive pulmonary aspergillosis in a patient receiving tacrolimus for dermatomyositis-associated interstitial lung disease. Respir Med Case Rep. 2015;16:163-5doi: 10.1016/j.rmcr.2015.10.008.
Mochizuki, E., Furuhashi, K., Fujisawa, T., Enomoto, N., Inui, N., Nakamura, Y., Kono, M., Hamada, E., Maekawa, M., & Suda, T. (2015). A case of treatment with voriconazole for chronic progressive pulmonary aspergillosis in a patient receiving tacrolimus for dermatomyositis-associated interstitial lung disease. Respiratory medicine case reports, 16163-5. https://doi.org/10.1016/j.rmcr.2015.10.008
Mochizuki, Eisuke, et al. "A case of treatment with voriconazole for chronic progressive pulmonary aspergillosis in a patient receiving tacrolimus for dermatomyositis-associated interstitial lung disease." Respiratory medicine case reports vol. 16 (2015): 163-5. doi: https://doi.org/10.1016/j.rmcr.2015.10.008
Mochizuki E, Furuhashi K, Fujisawa T, Enomoto N, Inui N, Nakamura Y, Kono M, Hamada E, Maekawa M, Suda T. A case of treatment with voriconazole for chronic progressive pulmonary aspergillosis in a patient receiving tacrolimus for dermatomyositis-associated interstitial lung disease. Respir Med Case Rep. 2015 Nov 03;16:163-5. doi: 10.1016/j.rmcr.2015.10.008. eCollection 2015. PMID: 26744690; PMCID: PMC4681998.
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New mechanistic insight into intramolecular arene hydroxylation initiated by (μ-1,2-peroxo)diiron(III) complexes with dinucleating ligands.

Dalton transactions (Cambridge, England : 2003)

Sekino M, Furutachi H, Tasaki K, Ishikawa T, Mori S, Fujinami S, Akine S, Sakata Y, Nomura T, Ogura T, Kitagawa T, Suzuki M.
PMID: 26646073
Dalton Trans. 2016 Jan 14;45(2):469-73. doi: 10.1039/c5dt04088d.

(μ-1,2-Peroxo)diiron(iii) complexes (-R) with dinucleating ligands (R-L) generated from the reaction of bis(μ-hydroxo)diiron(ii) complexes [Fe2(R-L)(OH)2](2+) (-R) with dioxygen in acetone at -20 °C provide a diiron-centred electrophilic oxidant, presumably diiron(iv)-oxo species, which is involved in aromatic ligand hydroxylation.

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Sekino M, Furutachi H, Tasaki K, et al. New mechanistic insight into intramolecular arene hydroxylation initiated by (μ-1,2-peroxo)diiron(III) complexes with dinucleating ligands. Dalton Trans. 2016;45(2):469-73doi: 10.1039/c5dt04088d.
Sekino, M., Furutachi, H., Tasaki, K., Ishikawa, T., Mori, S., Fujinami, S., Akine, S., Sakata, Y., Nomura, T., Ogura, T., Kitagawa, T., & Suzuki, M. (2016). New mechanistic insight into intramolecular arene hydroxylation initiated by (μ-1,2-peroxo)diiron(III) complexes with dinucleating ligands. Dalton transactions (Cambridge, England : 2003), 45(2), 469-73. https://doi.org/10.1039/c5dt04088d
Sekino, Mio, et al. "New mechanistic insight into intramolecular arene hydroxylation initiated by (μ-1,2-peroxo)diiron(III) complexes with dinucleating ligands." Dalton transactions (Cambridge, England : 2003) vol. 45,2 (2016): 469-73. doi: https://doi.org/10.1039/c5dt04088d
Sekino M, Furutachi H, Tasaki K, Ishikawa T, Mori S, Fujinami S, Akine S, Sakata Y, Nomura T, Ogura T, Kitagawa T, Suzuki M. New mechanistic insight into intramolecular arene hydroxylation initiated by (μ-1,2-peroxo)diiron(III) complexes with dinucleating ligands. Dalton Trans. 2016 Jan 14;45(2):469-73. doi: 10.1039/c5dt04088d. PMID: 26646073.
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Microwave Spectrum and Molecular Conformation of delta-Valerolactam.

Journal of molecular spectroscopy

Kuze N, Funahashi H, Ogawa M, Tajiri H, Ohta Y, Usami T, Sakaizumi T, Ohashi O.
PMID: 10547320
J Mol Spectrosc. 1999 Dec;198(2):381-386. doi: 10.1006/jmsp.1999.7959.

Microwave rotational spectra for normal and N-deuterated species of delta-valerolactam (2-piperidinone) were observed in the frequency range from 8 to 40 GHz. The spectra of the ground vibrational states for two isotopic species and the excited vibrational states for...

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Kuze N, Funahashi H, Ogawa M, et al. Microwave Spectrum and Molecular Conformation of delta-Valerolactam. J Mol Spectrosc. 1999;198(2):381-386doi: 10.1006/jmsp.1999.7959.
Kuze, N., Funahashi, H., Ogawa, M., Tajiri, H., Ohta, Y., Usami, T., Sakaizumi, T., & Ohashi, O. (1999). Microwave Spectrum and Molecular Conformation of delta-Valerolactam. Journal of molecular spectroscopy, 198(2), 381-386. https://doi.org/10.1006/jmsp.1999.7959
Kuze, et al. "Microwave Spectrum and Molecular Conformation of delta-Valerolactam." Journal of molecular spectroscopy vol. 198,2 (1999): 381-386. doi: https://doi.org/10.1006/jmsp.1999.7959
Kuze N, Funahashi H, Ogawa M, Tajiri H, Ohta Y, Usami T, Sakaizumi T, Ohashi O. Microwave Spectrum and Molecular Conformation of delta-Valerolactam. J Mol Spectrosc. 1999 Dec;198(2):381-386. doi: 10.1006/jmsp.1999.7959. PMID: 10547320.
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Phylogenetic identification of n-alkane assimilating Candida yeasts based on nucleotide divergence in the 59 end of LSU rDNA gene.

The Journal of general and applied microbiology

Arie M, Matsuda H, Furuhashi K, Takagi M.
PMID: 12483577
J Gen Appl Microbiol. 2000 Oct;46(5):257-262. doi: 10.2323/jgam.46.257.

Phylogenetic relationships of several species within the n-alkane assimilating Candida yeasts were investigated by using characters from the nucleotide sequence of the variable D1/D2 region at the 5' end of a large-subunit (26S) ribosomal DNA (rDNA) gene. First the...

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Arie M, Matsuda H, Furuhashi K, et al. Phylogenetic identification of n-alkane assimilating Candida yeasts based on nucleotide divergence in the 59 end of LSU rDNA gene. J Gen Appl Microbiol. 2000;46(5):257-262doi: 10.2323/jgam.46.257.
Arie, M., Matsuda, H., Furuhashi, K., & Takagi, M. (2000). Phylogenetic identification of n-alkane assimilating Candida yeasts based on nucleotide divergence in the 59 end of LSU rDNA gene. The Journal of general and applied microbiology, 46(5), 257-262. https://doi.org/10.2323/jgam.46.257
Arie, Mami, et al. "Phylogenetic identification of n-alkane assimilating Candida yeasts based on nucleotide divergence in the 59 end of LSU rDNA gene." The Journal of general and applied microbiology vol. 46,5 (2000): 257-262. doi: https://doi.org/10.2323/jgam.46.257
Arie M, Matsuda H, Furuhashi K, Takagi M. Phylogenetic identification of n-alkane assimilating Candida yeasts based on nucleotide divergence in the 59 end of LSU rDNA gene. J Gen Appl Microbiol. 2000 Oct;46(5):257-262. doi: 10.2323/jgam.46.257. PMID: 12483577.
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Observation of rho/omega meson modification in nuclear matter.

Physical review letters

Ozawa K, En'yo H, Funahashi H, Kitaguchi M, Ishino M, Kanda H, Mihara S, Miyashita T, Murakami T, Muto R, Naruki M, Sakuma F, Sato HD, Tabaru T, Yamada S, Yokkaichi S, Yoshimura Y, Chiba J, Ieiri M, Nomachi M, Sasaki O, Sekimoto M, Tanaka KH, Hamagaki H.
PMID: 11384410
Phys Rev Lett. 2001 May 28;86(22):5019-22. doi: 10.1103/PhysRevLett.86.5019.

We measured the invariant mass spectra of electron-positron pairs in the target rapidity region of 12-GeV p+A reactions. We have observed a significant difference in the mass spectra below the omega meson between p+C and p+Cu interactions. This difference...

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Ozawa K, En'yo H, Funahashi H, et al. Observation of rho/omega meson modification in nuclear matter. Phys Rev Lett. 2001;86(22):5019-22doi: 10.1103/PhysRevLett.86.5019.
Ozawa, K., En'yo, H., Funahashi, H., Kitaguchi, M., Ishino, M., Kanda, H., Mihara, S., Miyashita, T., Murakami, T., Muto, R., Naruki, M., Sakuma, F., Sato, H. D., Tabaru, T., Yamada, S., Yokkaichi, S., Yoshimura, Y., Chiba, J., Ieiri, M., Nomachi, M., Sasaki, O., Sekimoto, M., Tanaka, K. H., & Hamagaki, H. (2001). Observation of rho/omega meson modification in nuclear matter. Physical review letters, 86(22), 5019-22. https://doi.org/10.1103/PhysRevLett.86.5019
Ozawa, K, et al. "Observation of rho/omega meson modification in nuclear matter." Physical review letters vol. 86,22 (2001): 5019-22. doi: https://doi.org/10.1103/PhysRevLett.86.5019
Ozawa K, En'yo H, Funahashi H, Kitaguchi M, Ishino M, Kanda H, Mihara S, Miyashita T, Murakami T, Muto R, Naruki M, Sakuma F, Sato HD, Tabaru T, Yamada S, Yokkaichi S, Yoshimura Y, Chiba J, Ieiri M, Nomachi M, Sasaki O, Sekimoto M, Tanaka KH, Hamagaki H. Observation of rho/omega meson modification in nuclear matter. Phys Rev Lett. 2001 May 28;86(22):5019-22. doi: 10.1103/PhysRevLett.86.5019. PMID: 11384410.
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Experimental signature of medium modifications for rho and omega mesons in the 12 GeV p+A reactions.

Physical review letters

Naruki M, Fukao Y, Funahashi H, Ishino M, Kanda H, Kitaguchi M, Mihara S, Miwa K, Miyashita T, Murakami T, Nakura T, Sakuma F, Togawa M, Yamada S, Yoshimura Y, En'yo H, Muto R, Tabaru T, Yokkaichi S, Chiba J, Ieiri M, Sasaki O, Sekimoto M, Tanaka KH, Hamagaki H, Ozawa K.
PMID: 16606257
Phys Rev Lett. 2006 Mar 10;96(9):092301. doi: 10.1103/PhysRevLett.96.092301. Epub 2006 Mar 10.

The invariant mass spectra of e+e- pairs produced in 12 GeV proton-induced nuclear reactions are measured at the KEK Proton Synchrotron. On the low-mass side of the meson peak, a significant enhancement over the known hadronic sources has been...

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Naruki M, Fukao Y, Funahashi H, et al. Experimental signature of medium modifications for rho and omega mesons in the 12 GeV p+A reactions. Phys Rev Lett. 2006;96(9):092301doi: 10.1103/PhysRevLett.96.092301.
Naruki, M., Fukao, Y., Funahashi, H., Ishino, M., Kanda, H., Kitaguchi, M., Mihara, S., Miwa, K., Miyashita, T., Murakami, T., Nakura, T., Sakuma, F., Togawa, M., Yamada, S., Yoshimura, Y., En'yo, H., Muto, R., Tabaru, T., Yokkaichi, S., Chiba, J., Ieiri, M., Sasaki, O., Sekimoto, M., Tanaka, K. H., Hamagaki, H., & Ozawa, K. (2006). Experimental signature of medium modifications for rho and omega mesons in the 12 GeV p+A reactions. Physical review letters, 96(9), 092301. https://doi.org/10.1103/PhysRevLett.96.092301
Naruki, M, et al. "Experimental signature of medium modifications for rho and omega mesons in the 12 GeV p+A reactions." Physical review letters vol. 96,9 (2006): 092301. doi: https://doi.org/10.1103/PhysRevLett.96.092301
Naruki M, Fukao Y, Funahashi H, Ishino M, Kanda H, Kitaguchi M, Mihara S, Miwa K, Miyashita T, Murakami T, Nakura T, Sakuma F, Togawa M, Yamada S, Yoshimura Y, En'yo H, Muto R, Tabaru T, Yokkaichi S, Chiba J, Ieiri M, Sasaki O, Sekimoto M, Tanaka KH, Hamagaki H, Ozawa K. Experimental signature of medium modifications for rho and omega mesons in the 12 GeV p+A reactions. Phys Rev Lett. 2006 Mar 10;96(9):092301. doi: 10.1103/PhysRevLett.96.092301. Epub 2006 Mar 10. PMID: 16606257.
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Effects of levulinic acid on 5-aminolevulinic acid production in heterotrophic cultures of Chlorella regularis YA-603.

Journal of bioscience and bioengineering

Ano A, Funahashi H, Nakao K, Nishizawa Y.
PMID: 16232722
J Biosci Bioeng. 2000;89(2):176-80. doi: 10.1016/s1389-1723(00)88733-2.

To investigate the effects of levulinic acid (LA) on extracellular 5-aminolevulinic acid (ALA) accumulation, a heterotrophic culture of Chlorella regularis YA-603 in basal medium containing 0 to 60 mM of LA was carried out. It was found that the...

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Ano A, Funahashi H, Nakao K, et al. Effects of levulinic acid on 5-aminolevulinic acid production in heterotrophic cultures of Chlorella regularis YA-603. J Biosci Bioeng. 2000;89(2):176-80doi: 10.1016/s1389-1723(00)88733-2.
Ano, A., Funahashi, H., Nakao, K., & Nishizawa, Y. (2000). Effects of levulinic acid on 5-aminolevulinic acid production in heterotrophic cultures of Chlorella regularis YA-603. Journal of bioscience and bioengineering, 89(2), 176-80. https://doi.org/10.1016/s1389-1723(00)88733-2
Ano, A, et al. "Effects of levulinic acid on 5-aminolevulinic acid production in heterotrophic cultures of Chlorella regularis YA-603." Journal of bioscience and bioengineering vol. 89,2 (2000): 176-80. doi: https://doi.org/10.1016/s1389-1723(00)88733-2
Ano A, Funahashi H, Nakao K, Nishizawa Y. Effects of levulinic acid on 5-aminolevulinic acid production in heterotrophic cultures of Chlorella regularis YA-603. J Biosci Bioeng. 2000;89(2):176-80. doi: 10.1016/s1389-1723(00)88733-2. PMID: 16232722.
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DNA secondary structure is influenced by genetic variation and alters susceptibility to de novo translocation.

Molecular cytogenetics

Kato T, Inagaki H, Tong M, Kogo H, Ohye T, Yamada K, Tsutsumi M, Emanuel BS, Kurahashi H.
PMID: 21899780
Mol Cytogenet. 2011 Sep 08;4:18. doi: 10.1186/1755-8166-4-18.

BACKGROUND: Cumulative evidence suggests that DNA secondary structures impact DNA replication, transcription and genomic rearrangements. One of the best studied examples is the recurrent constitutional t(11;22) in humans that is mediated by potentially cruciform-forming sequences at the breakpoints, palindromic...

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Kato T, Inagaki H, Tong M, et al. DNA secondary structure is influenced by genetic variation and alters susceptibility to de novo translocation. Mol Cytogenet. 2011;4:18doi: 10.1186/1755-8166-4-18.
Kato, T., Inagaki, H., Tong, M., Kogo, H., Ohye, T., Yamada, K., Tsutsumi, M., Emanuel, B. S., & Kurahashi, H. (2011). DNA secondary structure is influenced by genetic variation and alters susceptibility to de novo translocation. Molecular cytogenetics, 418. https://doi.org/10.1186/1755-8166-4-18
Kato, Takema, et al. "DNA secondary structure is influenced by genetic variation and alters susceptibility to de novo translocation." Molecular cytogenetics vol. 4 (2011): 18. doi: https://doi.org/10.1186/1755-8166-4-18
Kato T, Inagaki H, Tong M, Kogo H, Ohye T, Yamada K, Tsutsumi M, Emanuel BS, Kurahashi H. DNA secondary structure is influenced by genetic variation and alters susceptibility to de novo translocation. Mol Cytogenet. 2011 Sep 08;4:18. doi: 10.1186/1755-8166-4-18. PMID: 21899780; PMCID: PMC3197554.
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Keys to the blow flies of Taiwan, with a checklist of recorded species and the description of a new species of Paradichosia Senior-White (Diptera, Calliphoridae).

ZooKeys

Yang ST, Kurahashi H, Shiao SF.
PMID: 25152681
Zookeys. 2014 Aug 14;(434):57-109. doi: 10.3897/zookeys.434.7540. eCollection 2014.

BLOW FLIES (DIPTERA: Calliphoridae) show a great diversity in behavior and ecology, play important roles in ecosystems, and have medical and forensic importance to humans. Despite this, the taxonomy and classification of Taiwan's Calliphoridae have rarely been studied. In...

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Yang ST, Kurahashi H, Shiao SF. Keys to the blow flies of Taiwan, with a checklist of recorded species and the description of a new species of Paradichosia Senior-White (Diptera, Calliphoridae). Zookeys. 2014;(434):57-109doi: 10.3897/zookeys.434.7540.
Yang, S. T., Kurahashi, H., & Shiao, S. F. (2014). Keys to the blow flies of Taiwan, with a checklist of recorded species and the description of a new species of Paradichosia Senior-White (Diptera, Calliphoridae). ZooKeys, (434), 57-109. https://doi.org/10.3897/zookeys.434.7540
Yang, Shih-Tsai, et al. "Keys to the blow flies of Taiwan, with a checklist of recorded species and the description of a new species of Paradichosia Senior-White (Diptera, Calliphoridae)." ZooKeys vol. ,434 (2014): 57-109. doi: https://doi.org/10.3897/zookeys.434.7540
Yang ST, Kurahashi H, Shiao SF. Keys to the blow flies of Taiwan, with a checklist of recorded species and the description of a new species of Paradichosia Senior-White (Diptera, Calliphoridae). Zookeys. 2014 Aug 14;(434):57-109. doi: 10.3897/zookeys.434.7540. eCollection 2014. PMID: 25152681; PMCID: PMC4141167.
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Association of HCV core antigen seropositivity with long-term mortality in patients on regular hemodialysis.

Nephron extra

Kato A, Takita T, Furuhashi M, Fujimoto T, Suzuki H, Maruyama Y, Sakao Y, Miyajima H.
PMID: 22619670
Nephron Extra. 2012 Jan;2(1):76-86. doi: 10.1159/000337333. Epub 2012 Mar 28.

Anti-hepatitis C virus (HCV) antibody seropositivity is independently associated with poor prognosis in hemodialysis (HD) patients. However, anti-HCV antibody cannot distinguish between patients with active infection and those who have recovered from infection. We therefore aimed in this study...

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Kato A, Takita T, Furuhashi M, et al. Association of HCV core antigen seropositivity with long-term mortality in patients on regular hemodialysis. Nephron Extra. 2012;2(1):76-86doi: 10.1159/000337333.
Kato, A., Takita, T., Furuhashi, M., Fujimoto, T., Suzuki, H., Maruyama, Y., Sakao, Y., & Miyajima, H. (2012). Association of HCV core antigen seropositivity with long-term mortality in patients on regular hemodialysis. Nephron extra, 2(1), 76-86. https://doi.org/10.1159/000337333
Kato, Akihiko, et al. "Association of HCV core antigen seropositivity with long-term mortality in patients on regular hemodialysis." Nephron extra vol. 2,1 (2012): 76-86. doi: https://doi.org/10.1159/000337333
Kato A, Takita T, Furuhashi M, Fujimoto T, Suzuki H, Maruyama Y, Sakao Y, Miyajima H. Association of HCV core antigen seropositivity with long-term mortality in patients on regular hemodialysis. Nephron Extra. 2012 Jan;2(1):76-86. doi: 10.1159/000337333. Epub 2012 Mar 28. PMID: 22619670; PMCID: PMC3350349.
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