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Showing 1 to 12 of 39 entries
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Mini Open Foraminotomy for Cervical Radiculopathy: A Comparison of Large Tubular and TrimLine Retractors.

Asian spine journal

Uehara M, Takahashi J, Kuraishi S, Shimizu M, Ikegami S, Futatsugi T, Aoki K, Mukaiyama K, Ogihara N, Hashidate H, Hirabayashi H, Kato H.
PMID: 26240713
Asian Spine J. 2015 Aug;9(4):548-52. doi: 10.4184/asj.2015.9.4.548. Epub 2015 Jul 28.

STUDY DESIGN: Retrospective chart review.PURPOSE: A comparison of mini open foraminotomy (MOF) for cervical radiculopathy using either large tubular (LT) or TrimLine (TL) retractors.OVERVIEW OF LITERATURE: Posterior foraminotomy relieves compression of the cervical nerve root in radiculopathy patients. However,...

Comparison of Clinical and Radiological Results of Posterolateral Fusion and Posterior Lumbar Interbody Fusion in the Treatment of L4 Degenerative Lumbar Spondylolisthesis.

Asian spine journal

Kuraishi S, Takahashi J, Mukaiyama K, Shimizu M, Ikegami S, Futatsugi T, Hirabayashi H, Ogihara N, Hashidate H, Tateiwa Y, Kinoshita H, Kato H.
PMID: 26949470
Asian Spine J. 2016 Feb;10(1):143-52. doi: 10.4184/asj.2016.10.1.143. Epub 2016 Feb 16.

STUDY DESIGN: Multicenter analysis of two groups of patients surgically treated for degenerative L4 unstable spondylolisthesis.PURPOSE: To compare the clinical and radiographic outcomes of posterolateral fusion (PLF) and posterior lumbar interbody fusion (PLIF) for degenerative L4 unstable spondylolisthesis.OVERVIEW OF...

Complications Associated With Spine Surgery in Patients Aged 80 Years or Older: Japan Association of Spine Surgeons with Ambition (JASA) Multicenter Study.

Global spine journal

Kobayashi K, Imagama S, Ando K, Ishiguro N, Yamashita M, Eguchi Y, Matsumoto M, Ishii K, Hikata T, Seki S, Terai H, Suzuki A, Tamai K, Aramomi M, Ishikawa T, Kimura A, Inoue H, Inoue G, Miyagi M, Saito W, Yamada K, Hongo M, Nishimura H, Suzuki H, Nakano A, Watanabe K, Chikuda H, Ohya J, Aoki Y, Shimizu M, Futatsugi T, Mukaiyama K, Hasegawa M, Kiyasu K, Iizuka H, Iizuka Y, Kobayashi R, Nishida K, Kakutani K, Nakajima H, Murakami H, Demura S, Kato S, Yoshioka K, Namikawa T, Watanabe K, Nakanishi K, Nakagawa Y, Yoshimoto M, Fujiwara H, Nishida N, Imajo Y, Yamazaki M, Sakane M, Abe T, Fujii K, Kaito T, Furuya T, Orita S, Ohtori S.
PMID: 28989842
Global Spine J. 2017 Oct;7(7):636-641. doi: 10.1177/2192568217716144. Epub 2017 Jul 20.

STUDY DESIGN: Retrospective study of registry data.OBJECTIVES: Aging of society and recent advances in surgical techniques and general anesthesia have increased the demand for spinal surgery in elderly patients. Many complications have been described in elderly patients, but a...

Stimulation-dependent intraspinal microtubules and synaptic failure in Alzheimer's disease: a review.

International journal of Alzheimer's disease

Mitsuyama F, Futatsugi Y, Okuya M, Kawase T, Karagiozov K, Kato Y, Kanno T, Sano H, Nagao S, Koide T.
PMID: 22482073
Int J Alzheimers Dis. 2012;2012:519682. doi: 10.1155/2012/519682. Epub 2012 Mar 08.

There are many microtubules in axons and dendritic shafts, but it has been thought that there were fewer microtubules in spines. Recently, there have been four reports that observed the intraspinal microtubules. Because microtubules originate from the centrosome, these...

Enantioselectivity in the biotransformation of bicyclic monoterpene alcohols with the cultured suspension cells of Nicotiana tabacum.

Plant cell reports

Suga T, Hirata T, Hamada H, Futatsugi M.
PMID: 24258047
Plant Cell Rep. 1983 Aug;2(4):186-8. doi: 10.1007/BF00270099.

The enantiomeric pairs of borneol, isoborneol, and isopinocampheol were incubated with the cultured suspension cells of Nicotiana tabacum. One of each enantiomeric pair was preferentially transformed to the corresponding carbonyl compound. It was thus demonstrated that the cultured cells...

Molecular Roles of Cdk5 in Pain Signaling.

Drug discovery today. Therapeutic strategies

Utreras E, Futatsugi A, Pareek TK, Kulkarni AB.
PMID: 21253436
Drug Discov Today Ther Strateg. 2009 Sep;6(3):105-111. doi: 10.1016/j.ddstr.2009.04.004.

Injury and inflammation trigger activation of several critical cellular pathways in nociceptive signaling in the peripheral nervous system, but their precise molecular mechanisms have not been clearly defined. Cyclin-dependent kinase 5 (Cdk5), a serine/threonine kinase, is mainly expressed in...

Acoustic behavior of a rigidly backed poroelastic layer with periodic resonant inclusions by a multiple scattering approach.

The Journal of the Acoustical Society of America

Weisser T, Groby JP, Dazel O, Gaultier F, Deckers E, Futatsugi S, Monteiro L.
PMID: 26936546
J Acoust Soc Am. 2016 Feb;139(2):617-29. doi: 10.1121/1.4940669.

The acoustic response of a rigidly backed poroelastic layer with a periodic set of elastic cylindrical inclusions embedded is studied. A semi-analytical approach is presented, based on Biot's 1956 theory to account for the deformation of the skeleton, coupling...

Small structural changes of the imidazopyridine diacylglycerol acyltransferase 2 (DGAT2) inhibitors produce an improved safety profile.

MedChemComm

Futatsugi K, Huard K, Kung DW, Pettersen JC, Flynn DA, Gosset JR, Aspnes GE, Barnes RJ, Cabral S, Dowling MS, Fernando DP, Goosen TC, Gorczyca WP, Hepworth D, Herr M, Lavergne S, Li Q, Niosi M, Orr STM, Pardo ID, Perez SM, Purkal J, Schmahai TJ, Shirai N, Shoieb AM, Zhou J, Goodwin B.
PMID: 30108796
Medchemcomm. 2016 Nov 22;8(4):771-779. doi: 10.1039/c6md00564k. eCollection 2017 Apr 01.

Small molecule DGAT2 inhibitors have shown promise for the treatment of metabolic diseases in preclinical models. Herein, we report the first toxicological evaluation of imidazopyridine-based DGAT2 inhibitors and show that the arteriopathy associated with imidazopyridine

Plasmapheresis as a promising treatment option in apalutamide-associated toxic epidermal necrolysis.

The Journal of dermatology

Miyagawa A, Adachi T, Kobayashi Y, Takamiyagi S, Arakawa H, Futatsugi K, Inazumi T.
PMID: 34837271
J Dermatol. 2021 Nov 26; doi: 10.1111/1346-8138.16248. Epub 2021 Nov 26.

No abstract available.

Blood Glucose Control Strategy for Type 2 Diabetes Patients With COVID-19.

Frontiers in cardiovascular medicine

Futatsugi H, Iwabu M, Okada-Iwabu M, Okamoto K, Amano Y, Morizaki Y, Kadowaki T, Yamauchi T.
PMID: 33195481
Front Cardiovasc Med. 2020 Oct 28;7:593061. doi: 10.3389/fcvm.2020.593061. eCollection 2020.

Since December 2019, coronavirus disease 2019 (COVID-19) caused by a novel coronavirus has spread all over the world affecting tens of millions of people. Another pandemic affecting the modern world, type 2 diabetes mellitus is among the major risk...

Comparison of cisplatin-induced nephrotoxicity between single-dose and split-dose administration to rats.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Fukushima K, Futatsugi A, Maekawa M, Naito S, Okada A, Sugioka N.
PMID: 34999374
Biomed Pharmacother. 2022 Jan 06;147:112619. doi: 10.1016/j.biopha.2022.112619. Epub 2022 Jan 06.

To prevent cisplatin (CDDP)-induced nephrotoxicity, co-treatment with massive hydration is essential for its clinical use. However, some patients are ineligible for this treatment. For such patients, a split dose of CDDP has been suggested as an alternative strategy. This...

Detection of Mycoplasma Contamination in Transplanted Retinal Cells by Rapid and Sensitive Polymerase Chain Reaction Test.

International journal of molecular sciences

Sugita S, Hono A, Fujino S, Futatsugi Y, Yunomae Y, Shimizu N, Takahashi M.
PMID: 34830437
Int J Mol Sci. 2021 Nov 21;22(22). doi: 10.3390/ijms222212555.

Contamination of cells/tissues by infectious pathogens (e.g., fungi, viruses, or bacteria, including mycoplasma) is a major problem in cell-based transplantation. In this study, we tested a polymerase chain reaction (PCR) method to provide rapid, simple, and sensitive detection of...

Showing 1 to 12 of 39 entries