Advanced Search
Display options
Filter resources
Text Availability
Article type
Publication date
Species
Language
Sex
Age
Showing 1 to 12 of 101 entries
Sorted by: Best Match Show Resources per page
Trial watch: Naked and vectored DNA-based anticancer vaccines.

Oncoimmunology

Bloy N, Buqué A, Aranda F, Castoldi F, Eggermont A, Cremer I, Sautès-Fridman C, Fucikova J, Galon J, Spisek R, Tartour E, Zitvogel L, Kroemer G, Galluzzi L.
PMID: 26155408
Oncoimmunology. 2015 Apr 02;4(5):e1026531. doi: 10.1080/2162402X.2015.1026531. eCollection 2015 May.

One type of anticancer vaccine relies on the administration of DNA constructs encoding one or multiple tumor-associated antigens (TAAs). The ultimate objective of these preparations, which can be naked or vectored by non-pathogenic viruses, bacteria or yeast cells, is...

Trial watch: Tumor-targeting monoclonal antibodies for oncological indications.

Oncoimmunology

Vacchelli E, Pol J, Bloy N, Eggermont A, Cremer I, Fridman WH, Galon J, Marabelle A, Kohrt H, Zitvogel L, Kroemer G, Galluzzi L.
PMID: 25949870
Oncoimmunology. 2015 Feb 03;4(1):e985940. doi: 10.4161/2162402X.2014.985940. eCollection 2015 Jan.

An expanding panel of monoclonal antibodies (mAbs) that specifically target malignant cells or intercept trophic factors delivered by the tumor stroma is now available for cancer therapy. These mAbs can exert direct antiproliferative/cytotoxic effects as they inhibit pro-survival signal...

Trial watch: Dendritic cell-based anticancer therapy.

Oncoimmunology

Bloy N, Pol J, Aranda F, Eggermont A, Cremer I, Fridman WH, Fučíková J, Galon J, Tartour E, Spisek R, Dhodapkar MV, Zitvogel L, Kroemer G, Galluzzi L.
PMID: 25941593
Oncoimmunology. 2014 Dec 21;3(11):e963424. doi: 10.4161/21624011.2014.963424. eCollection 2014 Nov.

The use of patient-derived dendritic cells (DCs) as a means to elicit therapeutically relevant immune responses in cancer patients has been extensively investigated throughout the past decade. In this context, DCs are generally expanded, exposed to autologous tumor cell...

The immune landscape of human tumors: Implications for cancer immunotherapy.

Oncoimmunology

Bindea G, Mlecnik B, Angell HK, Galon J.
PMID: 24800163
Oncoimmunology. 2014 Jan 01;3(1):e27456. doi: 10.4161/onci.27456. Epub 2014 Jan 03.

Understanding the spontaneous immune response of cancer patients is critical for the design of efficient anticancer immunotherapies. The power of integrative tumor immunology approaches allowed for a comprehensive view of the immune system evolution in the course of tumor...

Intrinsic selectivity in capillary electrophoresis for chiral separations with dual cyclodextrin systems.

Analytical chemistry

Lelièvre F, Gareil P, Bahaddi Y, Galons H.
PMID: 21639191
Anal Chem. 1997 Feb 01;69(3):393-401. doi: 10.1021/ac960607r.

Defined as the ratio of the affinity factors of the analytes for a complexing agent, the intrinsic selectivity is representative of the very nature of the complexing agent. When more than one complexing agent are present in the background...

Trial watch: FDA-approved Toll-like receptor agonists for cancer therapy.

Oncoimmunology

Vacchelli E, Galluzzi L, Eggermont A, Fridman WH, Galon J, Sautès-Fridman C, Tartour E, Zitvogel L, Kroemer G.
PMID: 23162757
Oncoimmunology. 2012 Sep 01;1(6):894-907. doi: 10.4161/onci.20931.

Toll-like receptors (TLRs) have first been characterized for their capacity to detect conserved microbial components like lipopolysaccharide (LPS) and double-stranded RNA, resulting in the elicitation of potent (innate) immune responses against invading pathogens. More recently, TLRs have also been...

[Not Available].

Journal de chirurgie

Pagès F, Berger A, Zinzindohoué F, Kirilovsky A, Galon J, Fridman WH.
PMID: 22794075
J Chir (Paris). 2008 Dec;145(6):12S6-12S12. doi: 10.1016/S0021-7697(08)45002-0.

F. Pagès, A. Berger, F. Zinzindohoué, A. Kirilovsky, J. Galon, W.-H. Fridman Lymph node dissection is an integral part of the surgical resection of colon cancers; it completes the wide regional resection of tumor and it allows prognostic evaluation...

A finite difference method with periodic boundary conditions for simulations of diffusion-weighted magnetic resonance experiments in tissue.

Physics in medicine and biology

Russell G, Harkins KD, Secomb TW, Galons JP, Trouard TP.
PMID: 22297418
Phys Med Biol. 2012 Feb 21;57(4):N35-46. doi: 10.1088/0031-9155/57/4/N35. Epub 2012 Feb 01.

A new finite difference (FD) method for calculating the time evolution of complex transverse magnetization in diffusion-weighted magnetic resonance imaging and spectroscopy experiments is described that incorporates periodic boundary conditions. The new FD method relaxes restrictions on the allowable...

Trial Watch: Experimental Toll-like receptor agonists for cancer therapy.

Oncoimmunology

Galluzzi L, Vacchelli E, Eggermont A, Fridman WH, Galon J, Sautès-Fridman C, Tartour E, Zitvogel L, Kroemer G.
PMID: 22934262
Oncoimmunology. 2012 Aug 01;1(5):699-716. doi: 10.4161/onci.20696.

Toll-like receptors (TLRs) are prototypic pattern recognition receptors (PRRs) best known for their ability to activate the innate immune system in response to conserved microbial components such as lipopolysaccharide and double-stranded RNA. Accumulating evidence indicates that the function of...

Estimation of visceral fat in 9- to 13-year-old girls using dual-energy X-ray absorptiometry (DXA) and anthropometry.

Obesity science & practice

Lee V, Blew R, Hetherington-Rauth M, Blew D, Galons JP, Hagio T, Bea J, Lohman T, Going S.
PMID: 30338114
Obes Sci Pract. 2018 Sep 13;4(5):437-447. doi: 10.1002/osp4.297. eCollection 2018 Oct.

OBJECTIVES: Accumulation of visceral fat (VF) in children increases the risk of cardiovascular disease and type 2 diabetes, and measurement of VF in children using computed tomography and magnetic resonance imaging (MRI) is expensive. Dual-energy X-ray absorptiometry (DXA) may...

Immunoscore and its introduction in clinical practice.

The quarterly journal of nuclear medicine and molecular imaging : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of...

Galon J, Lanzi A.
PMID: 32107902
Q J Nucl Med Mol Imaging. 2020 Jun;64(2):152-161. doi: 10.23736/S1824-4785.20.03249-5. Epub 2020 Feb 27.

Current cancer classification is based on intrinsic tumor parameters such as characteristic of tumor cells, tumor progression, tumor invasion and the presence of distant metastases, as summarized by the AJCC/UICC-TNM stratification system. There is currently no immune-based classification of...

How do social and economic vulnerabilities shape the work of participating in care? Everyday experiences of people living with kidney failure in Argentina.

Social science & medicine (1982)

Roberti J, Alonso JP, Blas L, May C.
PMID: 34952327
Soc Sci Med. 2021 Dec 18;293:114666. doi: 10.1016/j.socscimed.2021.114666. Epub 2021 Dec 18.

BACKGROUND: A new chronic patient has emerged, with a burden of symptoms and treatment. Patients with kidney failure (KF) require complex and expensive treatments, and in underresourced contexts, they struggle to obtain quality and timely care, even in countries...

Showing 1 to 12 of 101 entries