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Showing 1 to 12 of 660 entries
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Membrane-disrupting iridium(iii) oligocationic organometallopeptides.

Chemical communications (Cambridge, England)

Salvadó I, Gamba I, Montenegro J, Martínez-Costas J, Brea JM, Loza MI, Vázquez López M, Vázquez ME.
PMID: 27538788
Chem Commun (Camb). 2016 Sep 21;52(73):11008-11. doi: 10.1039/c6cc05537k. Epub 2016 Aug 19.

A series of oligoarginine peptide derivatives containing cyclometallated iridium(iii) units display remarkable cytotoxicity, comparable to that of cisplatin. In vitro studies with unilamellar vesicles support a membrane-disrupting mechanism of action.

A User-Centered Approach: Understanding Client and Caregiver Needs and Preferences in the Development of mHealth Apps for Self-Management.

JMIR mHealth and uHealth

Bendixen RM, Fairman AD, Karavolis M, Sullivan C, Parmanto B.
PMID: 28951378
JMIR Mhealth Uhealth. 2017 Sep 26;5(9):e141. doi: 10.2196/mhealth.7136.

BACKGROUND: Many adolescents and young adults with chronic illness or disability often fail to develop the self-management skills necessary to independently handle medical and self-management routines. In light of these needs, we are developing iMHere 2.0 (Interactive Mobile Health...

Epidemiological, Clinical, and Paraclinic Aspect of Cutaneous Sarcoidosis in Black Africans.

Dermatology research and practice

Kaloga M, Gbéry IP, Bamba V, Kouassi YI, Ecra EJ, Diabate A, Kourouma S, Ahogo KC, Kouamé KA, Kassi K, Kouame K, Sangaré A.
PMID: 26633968
Dermatol Res Pract. 2015;2015:802824. doi: 10.1155/2015/802824. Epub 2015 Nov 08.

The specific objectives were to identify the epidemiology of cutaneous sarcoidosis and describe the clinical and laboratory aspects of the disease. Materials and Methods. We performed a descriptive cross-sectional study involving 24 referred cases of cutaneous sarcoidosis in 25...

Oxidized cholesterol as the driving force behind the development of Alzheimer's disease.

Frontiers in aging neuroscience

Gamba P, Testa G, Gargiulo S, Staurenghi E, Poli G, Leonarduzzi G.
PMID: 26150787
Front Aging Neurosci. 2015 Jun 19;7:119. doi: 10.3389/fnagi.2015.00119. eCollection 2015.

Alzheimer's disease (AD), the most common neurodegenerative disorder associated with dementia, is typified by the pathological accumulation of amyloid Aβ peptides and neurofibrillary tangles (NFT) within the brain. Considerable evidence indicates that many events contribute to AD progression, including...

PO-19 - Platelet (PLT) adhesion under flow condition in essential thrombocythemia (ET) and polycythemia vera (PV) is variably influenced according to patient mutational status.

Thrombosis research

Vignoli A, Tessarolo S, Marchetti M, Gamba S, Piras F, Finazzi G, van der Meijden PE, Swieringa F, Ten Cate H, Heemskerk JW, Rambaldi A, Falanga A.
PMID: 27161708
Thromb Res. 2016 Apr;140:S183. doi: 10.1016/S0049-3848(16)30152-9. Epub 2016 Apr 08.

INTRODUCTION: The myeloproliferative neoplasms ET and PV are characterized by a high incidence of both arterial and venous thrombosis, and/or microcirculatory disturbances. Three somatic mutations, i.e. JAK2-V617F, Calreticulin (CalR) and MPL, commonly found in these diseases, correlate with different...

Challenges in the delivery of therapies to melanoma brain metastases.

Current pharmacology reports

Gampa G, Vaidhyanathan S, Resman BW, Parrish KE, Markovic SN, Sarkaria JN, Elmquist WF.
PMID: 28546917
Curr Pharmacol Rep. 2016 Dec;2(6):309-325. doi: 10.1007/s40495-016-0072-z. Epub 2016 Nov 09.

Brain metastases are a major cause of morbidity and mortality in patients with advanced melanoma. Recent approval of several molecularly-targeted agents and biologics has brought hope to patients with this previously untreatable disease. However, patients with symptomatic melanoma brain...

Generation, Spectroscopic, and Chemical Characterization of an Octahedral Iron(V)-Nitrido Species with a Neutral Ligand Platform.

Journal of the American Chemical Society

Sabenya G, Lázaro L, Gamba I, Martin-Diaconescu V, Andris E, Weyhermüller T, Neese F, Roithova J, Bill E, Lloret-Fillol J, Costas M.
PMID: 28598599
J Am Chem Soc. 2017 Jul 12;139(27):9168-9177. doi: 10.1021/jacs.7b00429. Epub 2017 Jun 30.

Iron complex [Fe

Is lumbar facet joint tropism developmental or secondary to degeneration? An international, large-scale multicenter study by the AOSpine Asia Pacific Research Collaboration Consortium.

Scoliosis and spinal disorders

Samartzis D, Cheung JP, Rajasekaran S, Kawaguchi Y, Acharya S, Kawakami M, Satoh S, Chen WJ, Park CK, Lee CS, Foocharoen T, Nagashima H, Kuh S, Zheng Z, Condor R, Ito M, Iwasaki M, Jeong JH, Luk KD, Prijambodo B, Rege A, Jahng TA, Luo Z, Tassanawipas WA, Acharya N, Pokharel R, Shen Y, Ito T, Zhang Z, Aithala P J, Kumar GV, Jabir RA, Basu S, Li B, Moudgil V, Goss B, Sham P, Williams R.
PMID: 27252985
Scoliosis Spinal Disord. 2016 Feb 09;11:9. doi: 10.1186/s13013-016-0062-2. eCollection 2016.

BACKGROUND: Facet joint tropism is asymmetry in orientation of the bilateral facets. Some studies have shown that tropism may increase the risk of disc degeneration and herniations, as well as degenerative spondylolisthesis (DS). It remains controversial whether tropism is...

Rectal adenocarcinoma in patients with anorectal malformations: report of two cases and a review of the literature.

SpringerPlus

Midrio P, Battaglia S, Urso E, Castagnetti M, Gamba P.
PMID: 27722042
Springerplus. 2016 Sep 20;5(1):1623. doi: 10.1186/s40064-016-3263-5. eCollection 2016.

AIM: Anorectal malformation (ARM) is a rare congenital disorder of the anus and rectum. In the last 30 years virtually all patients born with ARM have survived and surgeons from adult care may be called to deal with new...

Land-use choices follow profitability at the expense of ecological functions in Indonesian smallholder landscapes.

Nature communications

Clough Y, Krishna VV, Corre MD, Darras K, Denmead LH, Meijide A, Moser S, Musshoff O, Steinebach S, Veldkamp E, Allen K, Barnes AD, Breidenbach N, Brose U, Buchori D, Daniel R, Finkeldey R, Harahap I, Hertel D, Holtkamp AM, Hörandl E, Irawan B, Jaya INS, Jochum M, Klarner B, Knohl A, Kotowska MM, Krashevska V, Kreft H, Kurniawan S, Leuschner C, Maraun M, Melati DN, Opfermann N, Pérez-Cruzado C, Prabowo WE, Rembold K, Rizali A, Rubiana R, Schneider D, Tjitrosoedirdjo SS, Tjoa A, Tscharntke T, Scheu S.
PMID: 27725673
Nat Commun. 2016 Oct 11;7:13137. doi: 10.1038/ncomms13137.

Smallholder-dominated agricultural mosaic landscapes are highlighted as model production systems that deliver both economic and ecological goods in tropical agricultural landscapes, but trade-offs underlying current land-use dynamics are poorly known. Here, using the most comprehensive quantification of land-use change...

Xylanase and feruloyl esterase from actinomycetes cultures could enhance sugarcane bagasse hydrolysis in the production of fermentable sugars.

Bioscience, biotechnology, and biochemistry

Rahmani N, Kahar P, Lisdiyanti P, Hermiati E, Lee J, Yopi, Prasetya B, Ogino C, Kondo A.
PMID: 29475403
Biosci Biotechnol Biochem. 2018 Feb 23;1-12. doi: 10.1080/09168451.2018.1438169. Epub 2018 Feb 23.

The addition of enzymes that are capable of degrading hemicellulose has a potential to reduce the need for commercial enzymes during biomass hydrolysis in the production of fermentable sugars. In this study, a high xylanase producing actinomycete strain (Kitasatospora...

First record of Eggplant Mealybug, Coccidohystrixinsolita (Hemiptera: Pseudococcidae), on Guam: Potentially a major pest.

Biodiversity data journal

Moore A, Watson GW, Bamba J.
PMID: 24855439
Biodivers Data J. 2014 Jan 23;(2):e1042. doi: 10.3897/BDJ.2.e1042. eCollection 2014.

The eggplant mealybug, Coccidohystrixinsolita (Green) (Hemiptera: Pseudococcidae), is recorded from the island of Guam in the Mariana Islands for the first time. Factors indicating that this introduced mealybug has the potential to become a pest of economic importance for...

Showing 1 to 12 of 660 entries