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Gastroenterology

Lens S, Forns X, García-Pagán JC.
PMID: 29526729
Gastroenterology. 2018 Apr;154(5):1551-1552. doi: 10.1053/j.gastro.2018.03.017. Epub 2018 Mar 08.

No abstract available.

Aphasia in a patient with acute hepatic encephalopathy associated with multifocal cortical brain lesions.

Neurologia (Barcelona, Spain)

Falgàs N, Alfaro I, Crespo G, Berenguer J, García-Pagán JC, Muñoz E.
PMID: 27157523
Neurologia (Engl Ed). 2016 May 05; doi: 10.1016/j.nrl.2016.03.005. Epub 2016 May 05.

No abstract available.

Aging Influences Hepatic Microvascular Biology and Liver Fibrosis in Advanced Chronic Liver Disease.

Aging and disease

Maeso-Díaz R, Ortega-Ribera M, Lafoz E, Lozano JJ, Baiges A, Francés R, Albillos A, Peralta C, García-Pagán JC, Bosch J, Cogger VC, Gracia-Sancho J.
PMID: 31440376
Aging Dis. 2019 Aug 01;10(4):684-698. doi: 10.14336/AD.2019.0127. eCollection 2019 Aug.

Advanced chronic liver disease (aCLD) represents a major public health concern. aCLD is more prevalent and severe in the elderly, carrying a higher risk of decompensation. We aimed at understanding how aging may impact on the pathophysiology of aCLD...

Next-generation sequencing in the diagnosis of non-cirrhotic splanchnic vein thrombosis.

Journal of hepatology

Magaz M, Alvarez-Larrán A, Colomer D, López-Guerra M, García-Criado MÁ, Mezzano G, Belmonte E, Olivas P, Soy G, Cervantes F, Darnell A, Ferrusquía-Acosta J, Baiges A, Turon F, Hernández-Gea V, García-Pagán JC.
PMID: 32679300
J Hepatol. 2021 Jan;74(1):89-95. doi: 10.1016/j.jhep.2020.06.045. Epub 2020 Jul 15.

BACKGROUND & AIMS: Myeloproliferative neoplasms (MPNs) are the most frequent cause of non-tumoural non-cirrhotic splanchnic vein thrombosis (NC-SVT). Diagnosis of MPN is based on blood cell count alterations, bone marrow histology, and detection of specific gene mutations. Next-generation sequencing...

Management of an acute variceal bleeding episode.

Clinical liver disease

Reverter E, García-Pagán JC.
PMID: 31186876
Clin Liver Dis (Hoboken). 2012 Nov 09;1(5):151-154. doi: 10.1002/cld.82. eCollection 2012 Nov.

No abstract available.

Endoscopic Cyanoacrylate Injection Versus Balloon-Occluded Retrograde Transvenous Obliteration for Prevention of Gastric Variceal Bleeding: A Randomized Controlled Trial.

Hepatology (Baltimore, Md.)

Luo X, Xiang T, Wu J, Wang X, Zhu Y, Xi X, Yan Y, Yang J, García-Pagán JC, Yang L.
PMID: 33445218
Hepatology. 2021 Oct;74(4):2074-2084. doi: 10.1002/hep.31718. Epub 2021 Sep 14.

BACKGROUND AND AIMS: The optimal treatment for gastric varices (GVs) is a topic that remains open for study. This study compared the efficacy and safety of endoscopic cyanoacrylate injection and balloon-occluded retrograde transvenous obliteration (BRTO) to prevent rebleeding in...

Divergences in Macrophage Activation Markers Soluble CD163 and Mannose Receptor in Patients With Non-cirrhotic and Cirrhotic Portal Hypertension.

Frontiers in physiology

Ørntoft NW, Blé M, Baiges A, Ferrusquia J, Hernández-Gea V, Turon F, Magaz M, Møller S, Møller HJ, Garcia-Pagan JC, Gronbaek H.
PMID: 34177608
Front Physiol. 2021 Jun 11;12:649668. doi: 10.3389/fphys.2021.649668. eCollection 2021.

INTRODUCTION: Macrophages are involved in development and progression of chronic liver disease and portal hypertension. The macrophage activation markers soluble (s)CD163 and soluble mannose receptor (sMR), are associated with portal hypertension in patient with liver cirrhosis but never investigated...

Management of the major complications of cirrhosis: Beyond guidelines.

Journal of hepatology

Garcia-Pagan JC, Francoz C, Montagnese S, Senzolo M, Mookerjee RP.
PMID: 34039484
J Hepatol. 2021 Jul;75:S135-S146. doi: 10.1016/j.jhep.2021.01.027.

Along with a growing understanding of the pathophysiology of cirrhosis and its complications, new therapies and management strategies have emerged in recent years. Many of these advances have helped inform the current EASL clinical practice guidelines

Transcriptomic Profiling of the Liver Sinusoidal Endothelium during Cirrhosis Reveals Stage-Specific Secretory Signature.

Cancers

Manicardi N, Fernández-Iglesias A, Abad-Jordà L, Royo F, Azkargorta M, Ortega-Ribera M, Sanfeliu-Redondo D, Martínez-Alcocer A, Elortza F, Hessheimer AJ, Fondevila C, Lozano JJ, García-Pagán JC, Bosch J, Cubero FJ, Albillos A, Vaquero J, Falcón-Pérez JM, Gracia-Sancho J.
PMID: 34072510
Cancers (Basel). 2021 May 29;13(11). doi: 10.3390/cancers13112688.

The poor prognosis of chronic liver disease (CLD) generates the need to investigate the evolving mechanisms of disease progression, thus disclosing therapeutic targets before development of clinical complications. Considering the central role of liver sinusoidal endothelial cells (LSECs) in...

Bacterial infections adversely influence the risk of decompensation and survival in compensated cirrhosis.

Journal of hepatology

Villanueva C, Albillos A, Genescà J, Garcia-Pagan JC, Brujats A, Calleja JL, Aracil C, Bañares R, Morillas RM, Poca M, Peñas B, Augustin S, Abraldes JG, Alvarado E, Torres F, Bosch J.
PMID: 33905794
J Hepatol. 2021 Sep;75(3):589-599. doi: 10.1016/j.jhep.2021.04.022. Epub 2021 Apr 24.

BACKGROUND & AIMS: The prognosis of compensated cirrhosis is good until decompensation. In decompensated cirrhosis, bacterial infections (BIs) are common and increase the risk of death. The incidence and prognostic implications of BIs in compensated cirrhosis are less-well characterized....

Combination of Model for End-Stage Liver Disease and Lactate Predicts Death in Patients Treated With Salvage Transjugular Intrahepatic Portosystemic Shunt for Refractory Variceal Bleeding.

Hepatology (Baltimore, Md.)

Walter A, Rudler M, Olivas P, Moga L, Trépo E, Robic MA, Ollivier-Hourmand I, Baiges A, Sutter O, Bouzbib C, Peron JM, Le Pennec V, Ganne-Carrié N, Garcia-Pagán JC, Mallet M, Larrue H, Dao T, Thabut D, Hernández-Gea V, Nault JC, Bureau C, Allaire M.
PMID: 34018627
Hepatology. 2021 Oct;74(4):2085-2101. doi: 10.1002/hep.31913. Epub 2021 Jul 19.

BACKGROUND AND AIMS: Data about the prognosis of salvage transjugular intrahepatic portosystemic shunt (TIPS) using covered stents for refractory variceal bleeding caused by portal hypertension are scarce. We aimed to assess survival and to identify predictors of mortality in...

Is it necessary to endoscopically screen all patients with hepatitis C and advanced fibrosis for esophageal varices?.

Nature clinical practice. Gastroenterology & hepatology

Garcia-Pagan JC.
PMID: 17502882
Nat Clin Pract Gastroenterol Hepatol. 2007 Jul;4(7):370-1. doi: 10.1038/ncpgasthep0841. Epub 2007 May 15.

No abstract available.

Showing 1 to 12 of 46 entries