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Showing 1 to 12 of 498 entries
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Antidepressant Potential of 5-HT3 Receptor Antagonist, N-n- propyl-3-ethoxyquinoxaline-2-carboxamide (6n).

Journal of young pharmacists : JYP

Mahesh R, Bhatt S, Devadoss T, Jindal A, Gautam B, Pandey D.
PMID: 23493308
J Young Pharm. 2012 Oct;4(4):235-44. doi: 10.4103/0975-1483.104367.

The present study was designed to evaluate the antidepressant potential of 5-HT3 receptor antagonist N-n-propyl-3-ethoxyquinoxaline-2-carboxamide (6n). The compound '6n' with optimum log P and pA 2 value identified from a series of compounds synthesized in our laboratory was subjected...

Dexamethasone exerts profound immunologic interference on treatment efficacy for recurrent glioblastoma.

British journal of cancer

Wong ET, Lok E, Gautam S, Swanson KD.
PMID: 26625224
Br J Cancer. 2015 Dec 01;113(11):1642. doi: 10.1038/bjc.2015.404.

No abstract available.

New Breast Pain Chart for Objective Record of Mastalgia.

The Indian journal of surgery

Gautam S, Srivastava A, Kataria K, Dhar A, Ranjan P, Kumar J.
PMID: 27358525
Indian J Surg. 2016 Jun;78(3):245-8. doi: 10.1007/s12262-016-1492-z. Epub 2016 May 23.

Mastalgia is the commonest affliction of mammary gland among ladies of the reproductive age group. Since etiopathogenesis and therapy are different for cyclical and noncyclical pain, it is imperative to ascertain the exact type correctly. This is usually done...

To Keep or Not to Keep? The Question of Crystallographic Waters for Enzyme Simulations in Organic Solvent.

Molecular simulation

Dahanayake JN, Gautam DN, Verma R, Mitchell-Koch KR.
PMID: 27403032
Mol Simul. 2016;42(12):1001-1013. doi: 10.1080/08927022.2016.1139108. Epub 2016 Mar 22.

The use of enzymes in non-aqueous solvents expands the use of biocatalysts to hydrophobic substrates, with the ability to tune selectivity of reactions through solvent selection. Non-aqueous enzymology also allows for fundamental studies on the role of water and...

Low dose chest CT protocol (50 mAs) as a routine protocol for comprehensive assessment of intrathoracic abnormality.

European journal of radiology open

Kubo T, Ohno Y, Nishino M, Lin PJ, Gautam S, Kauczor HU, Hatabu H.
PMID: 27957519
Eur J Radiol Open. 2016 Apr 27;3:86-94. doi: 10.1016/j.ejro.2016.04.001. eCollection 2016.

PURPOSE: To determine the diagnostic capability of low-dose CT (50 mAs) in comparison to standard-dose CT (150 mAs).MATERIALS AND METHODS: Fifty-nine consecutive patients underwent two non-contrast chest CT scans with different current-time products (50 and 150 mAs at 120...

In vitro evaluation of excess copper affecting seedlings and their biochemical characteristics in Carthamus tinctorius L. (variety PBNS-12).

Physiology and molecular biology of plants : an international journal of functional plant biology

Gautam S, Anjani K, Srivastava N.
PMID: 27186026
Physiol Mol Biol Plants. 2016 Jan;22(1):121-9. doi: 10.1007/s12298-016-0339-1. Epub 2016 Jan 22.

The present study was focused to recognize the changes in the Safflower (Carthamus tinctorius L. variety PBNS-12), when exposed to different concentration of copper (25, 50 and 100 μM) along with control (0.5 μM) for 10 and 20 days....

Pristimerin Induces Apoptosis in Prostate Cancer Cells by Down-regulating Bcl-2 through ROS-dependent Ubiquitin-proteasomal Degradation Pathway.

Journal of carcinogenesis & mutagenesis

Liu YB, Gao X, Deeb D, Arbab AS, Gautam SC.
PMID: 24877026
J Carcinog Mutagen. 2013 Nov 05;005. doi: 10.4172/2157-2518.S6-005.

Pristimerin is a quinonemethide triterpenoid with the potential of a promising anticancer agent. Pristimerin (PM) has shown anticancer activity against a range of cancer cell lines, but its activity for prostate cancer has not been adequately investigated. In the...

A Prospective Study to Evaluate the Reliability of Thyroid Imaging Reporting and Data System in Differentiation between Benign and Malignant Thyroid Lesions.

Journal of clinical imaging science

Srinivas MN, Amogh VN, Gautam MS, Prathyusha IS, Vikram NR, Retnam MK, Balakrishna BV, Kudva N.
PMID: 27014501
J Clin Imaging Sci. 2016 Feb 26;6:5. doi: 10.4103/2156-7514.177551. eCollection 2016.

OBJECTIVES: To evaluate diagnostic reliability of the daily use of thyroid imaging reporting and data system (TIRADS) classification proposed by Kwak et al., in differentiating between a benign and a malignant thyroid lesion, to calculate inter-observer variability in the...

A PCBM Electron Transport Layer Containing Small Amounts of Dual Polymer Additives that Enables Enhanced Perovskite Solar Cell Performance.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Zhu Z, Xue Q, He H, Jiang K, Hu Z, Bai Y, Zhang T, Xiao S, Gundogdu K, Gautam BR, Ade H, Huang F, Wong KS, Yip HL, Yang S, Yan H.
PMID: 27711265
Adv Sci (Weinh). 2015 Dec 10;3(9):1500353. doi: 10.1002/advs.201500353. eCollection 2016 Sep.

No abstract available.

IL1α and TNFα Induction of Monocyte Chemoattractant Protein-1 (MCP-1/JE) in Bone Marrow Stromal Cells: The Role of Protein Kinase C (PKC) and Protein Tyrosine Kinase (PTK) Activity.

Hematology (Amsterdam, Netherlands)

Xian-Xu Y, Pindolia KR, Janakiraman N, Chapman RA, Gautam SC.
PMID: 27416533
Hematology. 1998;3(3):235-50. doi: 10.1080/10245332.1998.11746396.

Chemotactic cytokines (chemokines) have been shown to influence myelopoiesis. Bone marrow stromal cell line +/+-1. LDA11 expresses MCP-1/JE chemokine upon stimulation with ILlα and TNFα. We have examined the role of PKC and PTK dependent protein phosphorylation in induction...

Three-dimensional brain magnetic resonance imaging segmentation via knowledge-driven decision theory.

Journal of medical imaging (Bellingham, Wash.)

Verma N, Muralidhar GS, Bovik AC, Cowperthwaite MC, Burnett MG, Markey MK.
PMID: 26158060
J Med Imaging (Bellingham). 2014 Oct;1(3):034001. doi: 10.1117/1.JMI.1.3.034001. Epub 2014 Oct 01.

Brain tissue segmentation on magnetic resonance (MR) imaging is a difficult task because of significant intensity overlap between the tissue classes. We present a new knowledge-driven decision theory (KDT) approach that incorporates prior information of the relative extents of...

Probing polymer/polymer interfaces.

Journal of the American Chemical Society

Harp GP, Gautam KS, Dhinojwala A.
PMID: 12095328
J Am Chem Soc. 2002 Jul 10;124(27):7908-9. doi: 10.1021/ja026528g.

Infrared-visible sum frequency generation spectroscopy (SFG) has been used to study the interface between poly(vinyl-N-octadecylcarbamate-co-vinyl acetate) (Comb) and deuterated or hydrogenated polystyrene (dPS or hPS) films. Strong methyl symmetric and Fermi resonance bands associated with the alkyl side chains...

Showing 1 to 12 of 498 entries