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Showing 1 to 12 of 90 entries
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Draft Genome Sequence of Neisseria gonorrhoeae Sequence Type 1407, a Multidrug-Resistant Clinical Isolate.

Genome announcements

Anselmo A, Ciammaruconi A, Carannante A, Neri A, Fazio C, Fortunato A, Palozzi AM, Vacca P, Fillo S, Lista F, Stefanelli P.
PMID: 26272575
Genome Announc. 2015 Aug 13;3(4). doi: 10.1128/genomeA.00903-15.

Gonorrhea may become untreatable due to the spread of resistant or multidrug-resistant strains. Cefixime-resistant gonococci belonging to sequence type 1407 have been described worldwide. We report the genome sequence of Neisseria gonorrhoeae strain G2891, a multidrug-resistant isolate of sequence...

A fluorimetric study of pindolol and its complexes with cyclodextrins.

Talanta

Gazpio C, Sánchez M, Zornoza A, Martín C, Martínez-Ohárriz C, Vélaz I.
PMID: 18969069
Talanta. 2003 Jun 13;60(2):477-82. doi: 10.1016/S0039-9140(03)00077-8.

Spectrofluorimetric characteristics of pindolol have been investigated with the aim of using this technique for analytical determinations. Other monosubstituted indole derivatives, 4-methoxy and 5-methoxyindole, have been also studied for comparative purposes. Corrected excitation and emission wavelengths in different solvents...

Early metabolic response to acute myocardial ischaemia in patients undergoing elective coronary angioplasty.

Open heart

Di Marino S, Viceconte N, Lembo A, Summa V, Tanzilli G, Raparelli V, Truscelli G, Mangieri E, Gaudio C, Cicero DO.
PMID: 29632675
Open Heart. 2018 Mar 10;5(1):e000709. doi: 10.1136/openhrt-2017-000709. eCollection 2018.

OBJECTIVE: Balloon-induced transient coronary ischaemia represents a model of myocardial ischaemia and reperfusion. We are interested in the very early systemic metabolic response to this event.METHODS: Blood samples of patients with stable angina (SA) were collected before and after...

Takotsubo syndrome (stress cardiomyopathy): an intriguing clinical condition in search of its identity.

The American journal of medicine

Pelliccia F, Greco C, Vitale C, Rosano G, Gaudio C, Kaski JC.
PMID: 24754972
Am J Med. 2014 Aug;127(8):699-704. doi: 10.1016/j.amjmed.2014.04.004. Epub 2014 Apr 19.

Takotsubo syndrome is a relatively frequent clinical entity presenting typically as an acute coronary syndrome in the absence of obstructive coronary artery disease and characterized angiographically by transient left ventricular systolic dysfunction, sparing the basal segments of the left...

Results from a First-in-Human Phase I Study of Siremadlin (HDM201) in Patients with Advanced Wild-Type .

Clinical cancer research : an official journal of the American Association for Cancer Research

Stein EM, DeAngelo DJ, Chromik J, Chatterjee M, Bauer S, Lin CC, Suarez C, De Vos F, Steeghs N, Cassier PA, Tai D, Kiladjian JJ, Yamamoto N, Mous R, Esteve J, Minami H, Ferretti S, Guerreiro N, Meille C, Radhakrishnan R, Pereira B, Mariconti L, Halilovic E, Fabre C, Carpio C.
PMID: 34862243
Clin Cancer Res. 2021 Dec 03; doi: 10.1158/1078-0432.CCR-21-1295. Epub 2021 Dec 03.

PURPOSE: This phase I, dose-escalation study investigated the recommended dose for expansion (RDE) of siremadlin, a p53-MDM2 inhibitor, in patients with wild-type EXPERIMENTAL DESIGN: Initial dosing regimens were: 1A (Day 1; 21-day cycle; dose 12.5-350 mg); 2A (Days 1-14;...

Impact of sacubitril/valsartan on implantable defibrillator eligibility in heart failure: a real-world experience.

European review for medical and pharmacological sciences

Monzo L, Gaudio C, Cicogna F, Tota C, Petronilli V, Mennuni S, De Ruvo E, Calò L.
PMID: 34604961
Eur Rev Med Pharmacol Sci. 2021 Sep;25(18):5690-5700. doi: 10.26355/eurrev_202109_26788.

OBJECTIVE: Current guidelines recommend an implantable cardiac defibrillator (ICD) in patients with symptomatic heart failure and reduced ejection fraction (HFrEF; left ventricular ejection fraction [LVEF] ≤35%) despite ≥3 months of optimal medical therapy. Recent observations demonstrated that sacubitril/valsartan induces...

Glutathione Infusion Before and 3 Days After Primary Angioplasty Blunts Ongoing NOX2-Mediated Inflammatory Response.

Journal of the American Heart Association

Tanzilli G, Arrivi A, Placanica A, Viceconte N, Cammisotto V, Nocella C, Barillà F, Torromeo C, Pucci G, Acconcia MC, Granatelli A, Basili S, Dominici M, Gaudio C, Carnevale R, Mangieri E.
PMID: 34533039
J Am Heart Assoc. 2021 Sep 21;10(18):e020560. doi: 10.1161/JAHA.120.020560. Epub 2021 Sep 17.

Background Glutathione is a water-soluble tripeptide with a potent oxidant scavenging activity. We hypothesized that glutathione administration immediately before and after primary angioplasty (primary percutaneous coronary intervention) could be effective in modulating immune cell activation, thereby preventing infarct expansion....

Assessment of Magnetic Resonance Imaging Changes and Functional Outcomes Among Adults With Severe Herpes Simplex Encephalitis.

JAMA network open

Sarton B, Jaquet P, Belkacemi D, de Montmollin E, Bonneville F, Sazio C, Frérou A, Conrad M, Daubin D, Chabanne R, Argaud L, Dailler F, Brulé N, Lerolle N, Maestraggi Q, Marechal J, Bailly P, Razazi K, Mateos F, Guidet B, Levrat A, Susset V, Lautrette A, Mira JP, El Kalioubie A, Robert A, Massri A, Albucher JF, Olivot JM, Conil JM, Boudma L, Timsit JF, Sonneville R, Silva S.
PMID: 34313743
JAMA Netw Open. 2021 Jul 01;4(7):e2114328. doi: 10.1001/jamanetworkopen.2021.14328.

IMPORTANCE: Current guidelines recommend brain magnetic resonance imaging (MRI) for clinical management of patients with severe herpes simplex encephalitis (HSE). However, the prognostic value of brain imaging has not been demonstrated in this setting.OBJECTIVE: To investigate the association between...

[Effect of traffic-light labeling on nutritional content and on consumption of carbonated beverages in EcuadorEfeito da rotulagem nutricional com modelo de semáforo no consumo de refrigerantes no Equador].

Revista panamericana de salud publica = Pan American journal of public health

Peñaherrera V, Carpio C, Sandoval L, Sánchez M, Cabrera T, Guerrero P, Borja I.
PMID: 31093205
Rev Panam Salud Publica. 2018 Dec 27;42:e177. doi: 10.26633/RPSP.2018.177. eCollection 2018.

OBJECTIVE: To evaluate the effect of "traffic-light" nutritional labeling on the purchase of soft drinks and on their nutritional content in Ecuador.METHODS: Two databases were used: the first was provided by Ecuador's National Agency for Health Regulation, Control, and...

Multiple Origins and Specific Evolution of CRISPR/Cas9 Systems in Minimal Bacteria (.

Frontiers in microbiology

Ipoutcha T, Tsarmpopoulos I, Talenton V, Gaspin C, Moisan A, Walker CA, Brownlie J, Blanchard A, Thebault P, Sirand-Pugnet P.
PMID: 31824468
Front Microbiol. 2019 Nov 21;10:2701. doi: 10.3389/fmicb.2019.02701. eCollection 2019.

CRISPR/Cas systems provide adaptive defense mechanisms against invading nucleic acids in prokaryotes. Because of its interest as a genetic tool, the Type II CRISPR/Cas9 system from

Biomarkers of response to ibrutinib plus nivolumab in relapsed diffuse large B-cell lymphoma, follicular lymphoma, or Richter's transformation.

Translational oncology

Hodkinson BP, Schaffer M, Brody JD, Jurczak W, Carpio C, Ben-Yehuda D, Avivi I, Forslund A, Özcan M, Alvarez J, Ceulemans R, Fourneau N, Younes A, Balasubramanian S.
PMID: 33395752
Transl Oncol. 2021 Jan;14(1):100977. doi: 10.1016/j.tranon.2020.100977. Epub 2020 Dec 06.

We analyzed potential biomarkers of response to ibrutinib plus nivolumab in biopsies from patients with diffuse large B-cell lymphoma (DLBCL), follicular lymphoma (FL), and Richter's transformation (RT) from the LYM1002 phase I/IIa study, using programmed death ligand 1 (PD-L1)...

Endothelial progenitor cells predict long-term outcome in patients with coronary artery disease: Ten-year follow-up of the PROCREATION extended study.

International journal of cardiology

Pelliccia F, Pasceri V, Moretti A, Tanzilli G, Speciale G, Gaudio C.
PMID: 32522679
Int J Cardiol. 2020 Nov 01;318:123-125. doi: 10.1016/j.ijcard.2020.06.002. Epub 2020 Jun 06.

BACKGROUND: Levels of circulating endothelial progenitor cells (EPCs) are associated with the short-term prognosis of patients with coronary artery disease (CAD). No previous study, however, has ascertained if EPCs are related also to long-term outcome. We performed a pre-specified...

Showing 1 to 12 of 90 entries