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Showing 1 to 12 of 27 entries
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Effect of Crude Venom of .

Iranian journal of pharmaceutical research : IJPR

Ghasemi S, Salarian AA, Zare Mirakabadi A, Jafarinejad S, Ghazi-Khansari M.
PMID: 28979318
Iran J Pharm Res. 2017;16(2):648-652.

Scorpion venom toxicity is one of the major medical concerns from old years, due to its influence on human activities and health. From many years ago a lot of researches established to examine different aspects of venom toxicity and...

Cytotoxic Effect of Iranian Vipera lebetina Snake Venom on HUVEC Cells.

Iranian journal of pharmaceutical research : IJPR

Kakanj M, Ghazi-Khansari M, Zare Mirakabadi A, Daraei B, Vatanpour H.
PMID: 26185512
Iran J Pharm Res. 2015;14:109-14.

OBJECTIVE: Envenomation by heamotoxic snakes constituted a critical health occurrence in the world. Bleeding is the most sever consequence following snake bite with viperid and crothalid snakes. It is believed that the degradation of vascular membrane caused hemorrhage; in...

Comparative Measurement of In Vitro T-2 Toxin Cytotoxicity using Three Different Cytotoxicity Assays.

Toxicology mechanisms and methods

Heidari M, Ghazi-Khansari M, Khoshnoodi J, Shokri F.
PMID: 20021194
Toxicol Mech Methods. 2003;13(2):153-7. doi: 10.1080/15376510309841.

T-2 toxin is a secondary fungal metabolite produced by various species of fusarium. In this study, the in vitro cytotoxicity of T-2 toxin in the human hepatoma cell line (HepG2) was determined using three methods, including neutral red dye...

Radioprotective effect of melatonin in reducing oxidative stress in rat lenses.

Cell journal

Shirazi A, Haddadi GH, Asadi-Amoli F, Sakhaee S, Ghazi-Khansari M, Avand A.
PMID: 23508093
Cell J. 2011;13(2):79-82. Epub 2011 Aug 24.

OBJECTIVE: Ocular morbidity is widely observed when radiotherapy includes the orbit. Oxidative stress generated by irradiation is responsible for this complication. In different studies, it has been shown that melatonin has antioxidative properties and a radioprotective role. The aim...

Anti-.

Iranian journal of parasitology

Niyyati M, Sasani R, Mohebali M, Ghazikhansari M, Kargar F, Hajialilo E, Rezaeian M.
PMID: 30069201
Iran J Parasitol. 2018 Apr-Jun;13(2):180-185.

BACKGROUND: This study aimed to investigate the anti-METHODS: The present study was conducted in the School of Public Health, Tehran University of Medical sciences, Tehran, Iran during 2015-2016. Cysts of RESULTS: In none of the solutions in the manufacturer's...

Study of the cardioprotective effects of crocin on Human Cardiac Myocyte cells and reduction of oxidative stress produced by aluminum phosphide poisoning.

The Journal of pharmacy and pharmacology

Naddafi M, Eghbal MA, Ghazi-Khansari M, Sattari MR, Azarmi Y.
PMID: 33793778
J Pharm Pharmacol. 2021 Oct 07;73(11):1539-1546. doi: 10.1093/jpp/rgaa066.

OBJECTIVES: The effects of Crocin as a cardioprotective material against Aluminum phosphide poisoning by reducing the oxidative stress is investigated.METHODS: The level of biomarkers of oxidative stress (Catalase, Superoxide dismutase, Malondialdehyde and Protein carbonyl) were measured in the cell...

Assessment of tramadol pharmacokinetics in correlation with CYP2D6 and clinical symptoms.

Drug metabolism and personalized therapy

Ahmadimanesh M, Naeini MB, Rouini MR, Shadnia S, Ghazi-Khansari M.
PMID: 32598307
Drug Metab Pers Ther. 2020 Jun 29; doi: 10.1515/dmdi-2019-0021. Epub 2020 Jun 29.

Objectives Due to lack of adequate data on tramadol kinetic in relevance of CYP2D6 toxicity, this study was designed to investigate the effect of CYP2D6 phenotype in tramadol poisoning. The saliva, urine and blood samples were taken at the...

Rapamycin protects testes against germ cell apoptosis and oxidative stress induced by testicular ischemia-reperfusion.

Iranian journal of basic medical sciences

Ghasemnejad-Berenji M, Ghazi-Khansari M, Yazdani I, Saravi SSS, Nobakht M, Abdollahi A, Ansari JM, Ghasemnejad-Berenji H, Pashapour S, Dehpour AR.
PMID: 29085582
Iran J Basic Med Sci. 2017 Aug;20(8):905-911. doi: 10.22038/IJBMS.2017.9112.

OBJECTIVES: Rapamycin is an immunosuppressant compound with a broad spectrum of pharmaco-logical activities. In recent years, it has been used successfully to decrease ischemia-reperfusion injury in several organ systems. The purpose of the present study was to examine the...

Validation of an Analytical Methodology for Determination of Oxytetracycline Residue in Milk by HPLC with UV Detection.

Toxicology mechanisms and methods

Khosrokhavar R, Hosseini MJ, Amini M, Pirali-Hamedani M, Ghazi-Khansari M, Bakhtiarian A.
PMID: 20020901
Toxicol Mech Methods. 2008;18(4):351-4. doi: 10.1080/15376510701610984.

ABSTRACT Oxytetracycline (OTC) is used for the prophylaxis and treatment of a great number of diseases since this antibiotic possesses broad-spectrum activity against many pathogenic organisms. The use of OTC has become a serious problem because of the possible...

Comparative Measurement of In Vitro Paraquat and Aflatoxin B1 Cytotoxicity Using Three Different Cytotoxicity Assays in Pheochromocytoma Cells (PC-12).

Toxicology mechanisms and methods

Mohammadi-Bardbori A, Nejati M, Esmaeili J, Ghafari H, Ghazi-Khansari M.
PMID: 20020925
Toxicol Mech Methods. 2008 Jan;18(9):685-9. doi: 10.1080/15376510701392377.

ABSTRACT Among the herbicides and mycotoxins, paraquat (PQ) and aflatoxin B1 (AFB1) are highly cytotoxic. In this study the toxicity of PQ and AFB1 in the cultured cell were determined using MTT [3-(4, 5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide], JG-B (Janus green...

Comparative measurement of cyanide and paraquat mitochondrial toxicity using two different mitochondrial toxicity assays.

Toxicology mechanisms and methods

Mohammadi-Bardbori A, Ghazi-Khansari M.
PMID: 20020976
Toxicol Mech Methods. 2007;17(2):87-91. doi: 10.1080/15376510600822664.

ABSTRACT Cyanide (KCN) and paraquat (PQ) are very toxic to mitochondria. In this study the toxicity of KCN and PQ in the isolated rat liver mitochondria was determined using the MTT [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide] assay and JG-B (Janus green B)...

High Performance Liquid Chromatography Coupled with Pre-column Derivatization for Determination of Oxidized Glutathione Level in Rats Exposed to Paraquat.

Iranian journal of pharmaceutical research : IJPR

Hami Z, Amini M, Kiani A, Ghazi-Khansari M.
PMID: 24523771
Iran J Pharm Res. 2013;12(4):911-6.

Glutathione (GSH) is one of the most important antioxidants that plays an essential role in detoxification of reactive oxygen species (ROS) which oxidizes to glutathione disulfide (GSSG). Paraquat (PQ), awidely used herbicide, causes pulmonary injury with the productionof ROS....

Showing 1 to 12 of 27 entries