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Showing 1 to 12 of 109 entries
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Validating Multidimensional Outcome Assessment Using the TBI Common Data Elements: An Analysis of the TRACK-TBI Pilot Sample.

Journal of neurotrauma

Nelson LD, Ranson J, Ferguson AR, Giacino J, Okonkwo DO, Valadka A, Manley G, McCrea M.
PMID: 28595478
J Neurotrauma. 2017 Jun 08; doi: 10.1089/neu.2017.5139. Epub 2017 Jun 08.

The Glasgow Outcome Scale-Extended (GOSE) is often the primary outcome measure in clinical trials for traumatic brain injury (TBI). Although the GOSE's capture of global function outcome has several strengths, concerns have been raised about its limited ability to...

Role of Prion Disease-Linked Mutations in the Intrinsically Disordered N-Terminal Domain of the Prion Protein.

Journal of chemical theory and computation

Cong X, Casiraghi N, Rossetti G, Mohanty S, Giachin G, Legname G, Carloni P.
PMID: 26583425
J Chem Theory Comput. 2013 Nov 12;9(11):5158-67. doi: 10.1021/ct400534k. Epub 2013 Nov 01.

Prion diseases are fatal neurodegenerative disorders in mammals and other animal species. In humans, about 15% of these maladies are caused by pathogenic mutations (PMs) in the gene encoding for the prion protein (PrP(C)). Seven PMs are located in...

Preventing transmission of infectious agents in the pediatric in-patients hematology-oncology setting: what is the role for non-pharmacological prophylaxis?.

Pediatric reports

Caselli D, Cesaro S, Livadiotti S, Ziino O, Paolicchi O, Zanazzo G, Milano GM, Licciardello M, Barone A, Cellini M, Raffaella de S, Giacchino M, Rossi MR, Aricò M, Castagnola E.
PMID: 21647282
Pediatr Rep. 2011 Feb 24;3(1):e9. doi: 10.4081/pr.2011.e9.

The most intensive chemotherapy regimens were used in the past for leukemia patients who were the main focus of trials on infections; today there are increasing numbers of children with solid cancer and considerable risk of infection who do...

Newborn interneurons in the accessory olfactory bulb promote mate recognition in female mice.

Frontiers in neuroscience

Oboti L, Schellino R, Giachino C, Chamero P, Pyrski M, Leinders-Zufall T, Zufall F, Fasolo A, Peretto P.
PMID: 21994486
Front Neurosci. 2011 Sep 28;5:113. doi: 10.3389/fnins.2011.00113. eCollection 2011.

In the olfactory bulb of adult rodents, local interneurons are constantly replaced by immature precursors derived from the subventricular zone. Whether any olfactory sensory process specifically relies on this cell renewal remains largely unclear. By using the well known...

Optimization of systemic treatments for chronic plaque psoriasis. Recommendations for switching and transitioning.

Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia

Gisondi P, Amerio P, Amoroso GF, Antonucci VA, Bardazzi F, Buongiorno MR, Bruni P, Campanati A, Caproni M, Carlesimo M, Carrera CG, Cianchino G, Cimmino G, Costanzo A, Cozzani E, Dapavo P, D'amico D, De Simone C, Del Giglio M, Di Nuzzo S, Gai F, Galluccio AG, Goffredo A, Gualdi G, Guarneri C, Kokelj F, Lasagni C, Loconsole F, Longo V, Malagoli P, Miracapillo A, Mugheddu C, Parodi A, Pellegrino M, Peserico A, Piaserico S, Pistone G, Potenza C, Plumari A, Stingeni L, Strippoli D, Travaglino M, Girolomoni G.
PMID: 24675369
G Ital Dermatol Venereol. 2013 Dec;148(6):1-10.

AIM: The aim of this study was to provide practical recommendations for optimizing the use of conventional and biological systemic treatments for moderate-severe chronic plaque psoriasis, particularly in case of transitioning and switching.METHODS: A total number of 147 dermatologists...

Two Brothers with Atypical .

Frontiers in immunology

Giardino G, De Luca M, Cirillo E, Palma P, Romano R, Valeriani M, Papetti L, Saunders C, Cancrini C, Pignata C.
PMID: 29312353
Front Immunol. 2017 Dec 21;8:1892. doi: 10.3389/fimmu.2017.01892. eCollection 2017.

Hemophagocytic lymphohistiocytosis (HLH) is a potentially fatal hyperinflammatory condition. Variants in different genes have been associated with the familial forms of the syndrome (FHL), usually presenting within the first 2 years of life. Due to increasing awareness of the...

Stem Cell Tracking with Nanoparticles for Regenerative Medicine Purposes: An Overview.

Stem cells international

Accomasso L, Gallina C, Turinetto V, Giachino C.
PMID: 26839568
Stem Cells Int. 2016;2016:7920358. doi: 10.1155/2016/7920358. Epub 2015 Dec 29.

Accurate and noninvasive stem cell tracking is one of the most important needs in regenerative medicine to determine both stem cell destinations and final differentiation fates, thus allowing a more detailed picture of the mechanisms involved in these therapies....

Molecular Mechanisms of Mitotane Action in Adrenocortical Cancer Based on In Vitro Studies.

Cancers

Lo Iacono M, Puglisi S, Perotti P, Saba L, Petiti J, Giachino C, Reimondo G, Terzolo M.
PMID: 34771418
Cancers (Basel). 2021 Oct 20;13(21). doi: 10.3390/cancers13215255.

Mitotane is the only approved drug for the treatment of advanced adrenocortical carcinoma and is increasingly used for postoperative adjuvant therapy. Mitotane action involves the deregulation of cytochromes P450 enzymes, depolarization of mitochondrial membranes, and accumulation of free cholesterol,...

Traumatic Brain Injury: What Is a Favorable Outcome?.

Journal of neurotrauma

Zuckerman D, Giacino J, Bodien Y.
PMID: 34861770
J Neurotrauma. 2021 Dec 03; doi: 10.1089/neu.2021.0356. Epub 2021 Dec 03.

Traumatic brain injury (TBI) results in disparate outcomes ranging from persistent disorders of consciousness to symptom resolution. Despite the breadth and complexity of TBI recovery, most clinical trials dichotomize outcome by establishing an arbitrary cut-point, above and below which...

Respiratory Manifestations in Primary Immunodeficiencies: Findings From a Pediatric and Adult Cohort.

Archivos de bronconeumologia

Romano R, Borrelli M, Cirillo E, Giardino G, Spadaro G, Crescenzi L, Mormile I, Venditto L, Pignata C, Santamaria F.
PMID: 33678477
Arch Bronconeumol (Engl Ed). 2021 Feb 05; doi: 10.1016/j.arbres.2021.01.019. Epub 2021 Feb 05.

No abstract available.

The genus .

ZooKeys

Allegro G, Giachino PM.
PMID: 34183882
Zookeys. 2021 Jun 16;1044:427-448. doi: 10.3897/zookeys.1044.60072. eCollection 2021.

The

Sperm retrieval by conventional testicular sperm extraction for assisted reproduction in patients with Zinner syndrome.

Clinical and experimental reproductive medicine

Cito G, Gemma L, Giachini C, Micelli E, Cocci A, Fucci R, Picone R, Sforza S, Nesi G, Santi R, Minervini A, Masieri L, Carini M, Coccia ME, Natali A.
PMID: 33486943
Clin Exp Reprod Med. 2021 Mar;48(1):85-90. doi: 10.5653/cerm.2020.03769. Epub 2021 Jan 25.

We present data from three Caucasian men with Zinner syndrome who attended our center for the treatment of primary couple's infertility. Each patient was scheduled for conventional testicular sperm extraction (cTESE) and cryopreservation. Sperm analysis confirmed absolute azoospermia. Patient...

Showing 1 to 12 of 109 entries