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Showing 1 to 12 of 45 entries
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Guidelines on the diagnosis and management of chronic liver disease in haemophilia.

Haemophilia : the official journal of the World Federation of Hemophilia

Preston FE, Dusheiko G, Lee CA, Ludlam CA, Giangrande PL.
PMID: 27213479
Haemophilia. 1995 Dec;1:42-4. doi: 10.1111/j.1365-2516.1995.tb00133.x.

No abstract available.

Rapid and Sensitive Detection of Breast Cancer Cells in Patient Blood with Nuclease-Activated Probe Technology.

Molecular therapy. Nucleic acids

Kruspe S, Dickey DD, Urak KT, Blanco GN, Miller MJ, Clark KC, Burghardt E, Gutierrez WR, Phadke SD, Kamboj S, Ginader T, Smith BJ, Grimm SK, Schappet J, Ozer H, Thomas A, McNamara JO, Chan CH, Giangrande PH.
PMID: 28918054
Mol Ther Nucleic Acids. 2017 Sep 15;8:542-557. doi: 10.1016/j.omtn.2017.08.004. Epub 2017 Aug 12.

A challenge for circulating tumor cell (CTC)-based diagnostics is the development of simple and inexpensive methods that reliably detect the diverse cells that make up CTCs. CTC-derived nucleases are one category of proteins that could be exploited to meet...

Aptamers: Cutting edge of cancer therapies.

Molecular therapy : the journal of the American Society of Gene Therapy

Shigdar S, Schrand B, Giangrande PH, de Franciscis V.
PMID: 34146729
Mol Ther. 2021 Aug 04;29(8):2396-2411. doi: 10.1016/j.ymthe.2021.06.010. Epub 2021 Jun 17.

The development of an aptamer-based therapeutic has rapidly progressed following the first two reports in the 1990s, underscoring the advantages of aptamer drugs associated with their unique binding properties. In 2004, the US Food and Drug Administration (FDA) approved...

Genetically informed, multilevel analysis of the Flynn Effect across four decades and three WISC versions.

Child development

Giangrande EJ, Beam CR, Finkel D, Davis DW, Turkheimer E.
PMID: 34762291
Child Dev. 2021 Nov 11; doi: 10.1111/cdev.13675. Epub 2021 Nov 11.

This study investigated the systematic rise in cognitive ability scores over generations, known as the Flynn Effect, across middle childhood and early adolescence (7-15 years; 291 monozygotic pairs, 298 dizygotic pairs; 89% White). Leveraging the unique structure of the...

Von Willebrand Factor Multimeric Assay in Acquired von Willebrand Disease Diagnosis: A Report of Experience from North Estonia Medical Centre.

Journal of laboratory physicians

Pikta M, Banys V, Szanto T, Joutsi-Korhonen L, Vaide I, Varik M, Lehtinen AE, Giangrande P, Laane E.
PMID: 34602781
J Lab Physicians. 2021 Sep;13(3):195-201. doi: 10.1055/s-0041-1730818. Epub 2021 Jun 28.

No abstract available.

Aptamer-miRNA-212 Conjugate Sensitizes NSCLC Cells to TRAIL.

Molecular therapy. Nucleic acids

Iaboni M, Russo V, Fontanella R, Roscigno G, Fiore D, Donnarumma E, Esposito CL, Quintavalle C, Giangrande PH, de Franciscis V, Condorelli G.
PMID: 27111415
Mol Ther Nucleic Acids. 2016 Mar 08;5:e289. doi: 10.1038/mtna.2016.5.

TNF-related apoptosis-inducing ligand (TRAIL) is a promising antitumor agent for its remarkable ability to selectively induce apoptosis in cancer cells, without affecting the viability of healthy bystander cells. The TRAIL tumor suppressor pathway is deregulated in many human malignancies...

Sensitivity of organized convective storms to model grid spacing in current and future climates.

Philosophical transactions. Series A, Mathematical, physical, and engineering sciences

Prein AF, Rasmussen RM, Wang D, Giangrande SE.
PMID: 33641457
Philos Trans A Math Phys Eng Sci. 2021 Apr 19;379(2195):20190546. doi: 10.1098/rsta.2019.0546. Epub 2021 Mar 01.

Mesoscale convective systems (MCSs) are complexes of thunderstorms that become organized and cover hundreds of kilometres over several hours. MCSs are prolific rain producers in the tropics and mid-latitudes and are the major cause of warm-season flooding. Traditionally, climate...

Living with haemophilia.

Archives of disease in childhood

Giangrande P.
PMID: 10490537
Arch Dis Child. 1999 Aug;81(2):195. doi: 10.1136/adc.81.2.195.

No abstract available.

THE MIDLATITUDE CONTINENTAL CONVECTIVE CLOUDS EXPERIMENT (MC3E).

Bulletin of the American Meteorological Society

Jensen MP, Petersen WA, Bansemer A, Bharadwaj N, Carey LD, Cecil DJ, Collis SM, Del Genio AD, Dolan B, Gerlach J, Giangrande SE, Heymsfield A, Heymsfield G, Kollias P, Lang TJ, Nesbitt SW, Neumann A, Poellot M, Rutledge SA, Schwaller M, Tokay A, Williams CR, Wolff DB, Xie S, Zipser EJ.
PMID: 32669729
Bull Am Meteorol Soc. 2016 Sep;97(9):1667-1686. doi: 10.1175/BAMS-D-14-00228.1. Epub 2016 Oct 18.

No abstract available.

Connecting the nervous and the immune systems in evolution.

Communications biology

Hartenstein V, Giangrande A.
PMID: 30271946
Commun Biol. 2018 Jun 07;1:64. doi: 10.1038/s42003-018-0070-2. eCollection 2018.

Despite their great importance for biomedical research, the intricate network of relationships between macro- and microglia, in terms of development, function and evolution, remains poorly understood. Drawing inspiration from the recent meeting "Of Glia and Microglia", held at the...

Pedobarographic and kinematic analysis in the functional evaluation of two post-operative forefoot offloading shoes.

Journal of foot and ankle research

Caravaggi P, Giangrande A, Berti L, Lullini G, Leardini A.
PMID: 26516351
J Foot Ankle Res. 2015 Oct 29;8:59. doi: 10.1186/s13047-015-0116-3. eCollection 2015.

BACKGROUND: Forefoot offloading shoes are special orthopaedic footwear designed to protect and unload the injured part of the foot after surgery and for conservative treatments. The offloading action is often achieved by transferring plantar load to the rearfoot via...

The airline passenger: current medical issues.

Travel medicine and infectious disease

Nicholson AN, Cummin AR, Giangrande PL.
PMID: 17291894
Travel Med Infect Dis. 2003 May;1(2):94-102. doi: 10.1016/S1477-8939(03)00060-7.

It is widely accepted that travel by air is unlikely to be a hazard to the vast majority of passengers. However, there are potentially adverse effects of cabin air of poor quality and of the reduced oxygen tension of...

Showing 1 to 12 of 45 entries