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Showing 1 to 12 of 19 entries
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Ethyleneglycol-Bis-((-aminoethyl ether) N,N,N(1),N(1), -Tetraacetic acid (EGTA) inhibits Leishmania donovani in vitro.

African journal of health sciences

Mbati PA, Abok K, Orago AS, Anjili CO, Githure JI, Koech DK.
PMID: 12153341
Afr J Health Sci. 1994 Nov;1(4):160-164.

Exposure of Leishmania donovani culture promastigotes to ethyleneglycol-bis-((-aminoethyl ether) N,N,N(1),N(1),-tetraacetic acid (EGTA) concentrations of between 0.2 to 1.6 mg/ml significantly inhibited their growth, though the different concentrations did not significantly differ between themselves on their effect on promastigotes in...

Determination of the optimal EDTA and Pentostam concentration in the treatment of Leishmania donovani-infected laboratory animal rodent models. .

African journal of health sciences

Mbati PA, Abok K, Orago AS, Anjili CO, Githure JI, Koech DK.
PMID: 12160454
Afr J Health Sci. 1995 Feb;2(1):254-255.

No abstract available.

Antimalarial activity of fractions isolated from Albizia gummifera and Aspilia mossambicensis crude extracts.

African journal of health sciences

Orulla AV, Rukunga GM, Chege GM, Kiarie F, Muthaura CN, Githure JI, Kofi-Tsekpo WM.
PMID: 17451297
Afr J Health Sci. 1996 May;3(2):44-6.

To identify the fractions of medicinal plant extracts containing the highest concentration of antimalarial principles, we tested the antimalarial activities of the crude or total extracts and two fractions from Albizia gummifera (Leguminosae) and three fractions from Aspilia mossambicencis...

Isolation and characterization of flagellates from rodents and canids in Masinga, Machakos District, Kenya. .

African journal of health sciences

Githure JI, Anjili CO, Ngumbi PM, Mwanyumba PM, Lugalia R, Koech DK, Kinoti GK.
PMID: 12160424
Afr J Health Sci. 1995 Nov;2(4):372-375.

A total of 728 animals comprising of 633 rodents and 95 canids were examined for leishmanial parasites. Flagellates were isolated from 67 out of 111 (60.4%) Acomys subspinosus (spiny mouse), 12 out of 143 (8.4% ) Mastomys natalensis (multimammate...

Screening of metal ion chelators against Leishmania donovani-infected Syrian hamsters. .

African journal of health sciences

Mbati PA, Abok K, Anjili CO, Orago AS, Kagai JM, Githure JI, Koech DK.
PMID: 12160448
Afr J Health Sci. 1995 Feb;2(1):223-227.

Leishmania donovani-infected Syrian hamsters were treated intraperitoneally with 0.23 mmoles/kg/day of EDTA, EGTA, HEEDTA and 100 mg/kg/day of Pentostam R. The control group received 0.1 ml of phosphate buffered saline. After 30 days of treatment, the animals were sacrificed....

Systematic-review and meta-analysis on effect of decontamination interventions on prevalence and concentration of Campylobacter spp. during primary processing of broiler chickens.

Food microbiology

Gichure JN, Kamau Njage PM, Wambui JM, Dykes GA, Buys EM, Coorey R.
PMID: 34809949
Food Microbiol. 2022 Apr;102:103923. doi: 10.1016/j.fm.2021.103923. Epub 2021 Oct 14.

Scientific advances in pathogen decontamination offer great potential to reduce Campylobacter spp. during primary processing. The aim of this study was to collate data from eligible studies using systematic review, meta-analysis followed by meta-regression. Random effect meta-analysis revealed heterogenous...

Multi-Indicator and Multistep Assessment of Malaria Transmission Risks in Western Kenya.

The American journal of tropical medicine and hygiene

Zhou G, Zhong D, Lee MC, Wang X, Atieli HE, Githure JI, Githeko AK, Kazura J, Yan G.
PMID: 33556042
Am J Trop Med Hyg. 2021 Feb 08; doi: 10.4269/ajtmh.20-1211. Epub 2021 Feb 08.

Malaria risk factor assessment is a critical step in determining cost-effective intervention strategies and operational plans in a regional setting. We develop a multi-indicator multistep approach to model the malaria risks at the population level in western Kenya. We...

Hyper-prevalence of submicroscopic Plasmodium falciparum infections in a rural area of western Kenya with declining malaria cases.

Malaria journal

Ochwedo KO, Omondi CJ, Magomere EO, Olumeh JO, Debrah I, Onyango SA, Orondo PW, Ondeto BM, Atieli HE, Ogolla SO, Githure J, Otieno ACA, Githeko AK, Kazura JW, Mukabana WR, Guiyan Y.
PMID: 34930283
Malar J. 2021 Dec 20;20(1):472. doi: 10.1186/s12936-021-04012-6.

BACKGROUND: The gold standard for diagnosing Plasmodium falciparum infection is microscopic examination of Giemsa-stained peripheral blood smears. The effectiveness of this procedure for infection surveillance and malaria control may be limited by a relatively high parasitaemia detection threshold. Persons...

Screening of metal ion chelators against Leishmania donovani-infected BALB/c mice.

African journal of health sciences

Mbati PA, Abok K, Orago AS, Anjili CO, Githure JI, Koech DK.
PMID: 12160455
Afr J Health Sci. 1995 Feb;2(1):256-257.

No abstract available.

Daily oviposition patterns of the African malaria mosquito Anopheles gambiae Giles (Diptera: Culicidae) on different types of aqueous substrates.

Journal of circadian rhythms

Sumba LA, Okoth K, Deng AL, Githure J, Knols BG, Beier JC, Hassanali A.
PMID: 15596009
J Circadian Rhythms. 2004 Dec 13;2(1):6. doi: 10.1186/1740-3391-2-6.

BACKGROUND: Anopheles gambiae Giles is the most important vector of human malaria in sub-Saharan Africa. Knowledge of the factors that influence its daily oviposition pattern is crucial if field interventions targeting gravid females are to be successful. This laboratory...

Differential Induction of Proteins in Anopheles gambiae sensu stricto (Diptera: Cullicidae) Larvae in Response to Heavy Metal Selection.

International journal of tropical insect science

Mireji PO, Keating J, Kenya E, Mbogo C, Nyambaka H, Osir E, Githure J, Beier J.
PMID: 20651951
Int J Trop Insect Sci. 2006 Dec;26(4):214-226. doi: 10.1017/S1742758406658955.

Investigations were conducted to establish the magnitude and pattern of differential expression of proteins due to generational selection of third instar An. gambiae s.s. larvae by cadmium, copper and lead heavy metals, three possible common urban pollutants.A susceptible strain...

Comparison of Giemsa and acridine orange stains for the diagnosis of Leishmania donovani in biopsies of infected hamsters. .

African journal of health sciences

Mbati PA, Abok K, Anjili CO, Orago AS, Kagai JM, Githure JI, Koech DK.
PMID: 12160449
Afr J Health Sci. 1995 Feb;2(1):228-231.

Identical impression smears of spleen, liver and bone marrow biopsy materials from Leishmania donovani-infected hamsters were stained using either acridine orange or Giemsa. Spleen parasite-loads calculated from the two stains for identical biopsy material were significantly different from each...

Showing 1 to 12 of 19 entries