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Acid- and Au(i)-mediated synthesis of hexathymidine-DNA-heterocycle chimeras, an efficient entry to DNA-encoded libraries inspired by drug structures.

Chemical science

Škopić MK, Salamon H, Bugain O, Jung K, Gohla A, Doetsch LJ, Dos Santos D, Bhat A, Wagner B, Brunschweiger A.
PMID: 28507705
Chem Sci. 2017 May 01;8(5):3356-3361. doi: 10.1039/c7sc00455a. Epub 2017 Feb 28.

Libraries of DNA-tagged compounds are a validated screening technology for drug discovery. They are synthesized through combinatorial iterations of alternated coding and preparative synthesis steps. Thus, large chemical space can be accessed for target-based screening. However, the need to...

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Škopić MK, Salamon H, Bugain O, et al. Acid- and Au(i)-mediated synthesis of hexathymidine-DNA-heterocycle chimeras, an efficient entry to DNA-encoded libraries inspired by drug structures. Chem Sci. 2017;8(5):3356-3361doi: 10.1039/c7sc00455a.
Škopić, M. K., Salamon, H., Bugain, O., Jung, K., Gohla, A., Doetsch, L. J., Dos Santos, D., Bhat, A., Wagner, B., & Brunschweiger, A. (2017). Acid- and Au(i)-mediated synthesis of hexathymidine-DNA-heterocycle chimeras, an efficient entry to DNA-encoded libraries inspired by drug structures. Chemical science, 8(5), 3356-3361. https://doi.org/10.1039/c7sc00455a
Škopić, Mateja Klika, et al. "Acid- and Au(i)-mediated synthesis of hexathymidine-DNA-heterocycle chimeras, an efficient entry to DNA-encoded libraries inspired by drug structures." Chemical science vol. 8,5 (2017): 3356-3361. doi: https://doi.org/10.1039/c7sc00455a
Škopić MK, Salamon H, Bugain O, Jung K, Gohla A, Doetsch LJ, Dos Santos D, Bhat A, Wagner B, Brunschweiger A. Acid- and Au(i)-mediated synthesis of hexathymidine-DNA-heterocycle chimeras, an efficient entry to DNA-encoded libraries inspired by drug structures. Chem Sci. 2017 May 01;8(5):3356-3361. doi: 10.1039/c7sc00455a. Epub 2017 Feb 28. PMID: 28507705; PMCID: PMC5416911.
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Growth of Spanish, BoerxAngora and BoerxSpanish goat kids fed milk replacer.

Small ruminant research : the journal of the International Goat Association

Luo J, Sahlu T, Cameron M, Goetsch AL.
PMID: 10760455
Small Rumin Res. 2000 May 01;36(2):189-194. doi: 10.1016/s0921-4488(99)00163-7.

Seventy-seven male kids were used to compare growth performance of Spanish (S, n=26), BoerxAngora (BA, n=21) and BoerxSpanish (BS, n=30) kids during the preweaning period. All kids were removed from does 3 days postpartum, moved indoors and randomly allocated...

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Luo J, Sahlu T, Cameron M, et al. Growth of Spanish, BoerxAngora and BoerxSpanish goat kids fed milk replacer. Small Rumin Res. 2000;36(2):189-194doi: 10.1016/s0921-4488(99)00163-7.
Luo, J., Sahlu, T., Cameron, M., & Goetsch, A. L. (2000). Growth of Spanish, BoerxAngora and BoerxSpanish goat kids fed milk replacer. Small ruminant research : the journal of the International Goat Association, 36(2), 189-194. https://doi.org/10.1016/s0921-4488(99)00163-7
Luo, et al. "Growth of Spanish, BoerxAngora and BoerxSpanish goat kids fed milk replacer." Small ruminant research : the journal of the International Goat Association vol. 36,2 (2000): 189-194. doi: https://doi.org/10.1016/s0921-4488(99)00163-7
Luo J, Sahlu T, Cameron M, Goetsch AL. Growth of Spanish, BoerxAngora and BoerxSpanish goat kids fed milk replacer. Small Rumin Res. 2000 May 01;36(2):189-194. doi: 10.1016/s0921-4488(99)00163-7. PMID: 10760455.
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Adsorption energy, growth mode, and sticking probability of Ca on poly(methyl methacrylate) surfaces with and without electron damage.

Journal of the American Chemical Society

Zhu J, Goetsch P, Ruzycki N, Campbell CT.
PMID: 17465543
J Am Chem Soc. 2007 May 23;129(20):6432-41. doi: 10.1021/ja067437c. Epub 2007 Apr 28.

The adsorption of Ca atoms on pristine and electron-irradiated poly(methyl methacrylate) (PMMA) surfaces at 300 K has been studied by adsorption microcalorimetry, atomic beam/surface scattering, and low-energy He+ ion scattering spectroscopy (ISS). On pristine PMMA, the initial sticking probability...

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Zhu J, Goetsch P, Ruzycki N, et al. Adsorption energy, growth mode, and sticking probability of Ca on poly(methyl methacrylate) surfaces with and without electron damage. J Am Chem Soc. 2007;129(20):6432-41doi: 10.1021/ja067437c.
Zhu, J., Goetsch, P., Ruzycki, N., & Campbell, C. T. (2007). Adsorption energy, growth mode, and sticking probability of Ca on poly(methyl methacrylate) surfaces with and without electron damage. Journal of the American Chemical Society, 129(20), 6432-41. https://doi.org/10.1021/ja067437c
Zhu, Junfa, et al. "Adsorption energy, growth mode, and sticking probability of Ca on poly(methyl methacrylate) surfaces with and without electron damage." Journal of the American Chemical Society vol. 129,20 (2007): 6432-41. doi: https://doi.org/10.1021/ja067437c
Zhu J, Goetsch P, Ruzycki N, Campbell CT. Adsorption energy, growth mode, and sticking probability of Ca on poly(methyl methacrylate) surfaces with and without electron damage. J Am Chem Soc. 2007 May 23;129(20):6432-41. doi: 10.1021/ja067437c. Epub 2007 Apr 28. PMID: 17465543.
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About pneumocardiography, a functional test of the heart using breathing.

Zeitschrift fur Kreislaufforschung

DOETSCH H.
PMID: 18101435
Z Kreislaufforsch. 1948 Aug;37(15):428-40.

No abstract available.

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DOETSCH H. Ueber die Pneumokardiographie, eine Funktionsprüfung des Herzens mit Hilfe der Atmung. About pneumocardiography, a functional test of the heart using breathing. Z Kreislaufforsch. 1948;37(15):428-40
DOETSCH, H. (1948). Ueber die Pneumokardiographie, eine Funktionsprüfung des Herzens mit Hilfe der Atmung. About pneumocardiography, a functional test of the heart using breathing. Zeitschrift fur Kreislaufforschung, 37(15), 428-40.
DOETSCH, H. "Ueber die Pneumokardiographie, eine Funktionsprüfung des Herzens mit Hilfe der Atmung." About pneumocardiography, a functional test of the heart using breathing. Zeitschrift fur Kreislaufforschung vol. 37,15 (1948): 428-40.
DOETSCH H. Ueber die Pneumokardiographie, eine Funktionsprüfung des Herzens mit Hilfe der Atmung. About pneumocardiography, a functional test of the heart using breathing. Z Kreislaufforsch. 1948 Aug;37(15):428-40. German. PMID: 18101435.
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Mortality in Goitre Operations: An Analysis of a Series of 1,755 Operations During the Ten-Year Period, 1920-1929 Inc.

Annals of surgery

Goetsch E.
PMID: 17866610
Ann Surg. 1931 Aug;94(2):167-78. doi: 10.1097/00000658-193108000-00002.

No abstract available.

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Goetsch E. Mortality in Goitre Operations: An Analysis of a Series of 1,755 Operations During the Ten-Year Period, 1920-1929 Inc. Ann Surg. 1931;94(2):167-78doi: 10.1097/00000658-193108000-00002.
Goetsch, E. (1931). Mortality in Goitre Operations: An Analysis of a Series of 1,755 Operations During the Ten-Year Period, 1920-1929 Inc. Annals of surgery, 94(2), 167-78. https://doi.org/10.1097/00000658-193108000-00002
Goetsch, E. "Mortality in Goitre Operations: An Analysis of a Series of 1,755 Operations During the Ten-Year Period, 1920-1929 Inc." Annals of surgery vol. 94,2 (1931): 167-78. doi: https://doi.org/10.1097/00000658-193108000-00002
Goetsch E. Mortality in Goitre Operations: An Analysis of a Series of 1,755 Operations During the Ten-Year Period, 1920-1929 Inc. Ann Surg. 1931 Aug;94(2):167-78. doi: 10.1097/00000658-193108000-00002. PMID: 17866610; PMCID: PMC1391481.
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Etching of Si(100)-2 x 1 with chlorine: Reaction pathways, energy anisotropies, and atomic-scale phenomena.

Physical review. B, Condensed matter

Aldao CM, Chander M, Goetsch DA, Weaver JH.
PMID: 9979829
Phys Rev B Condens Matter. 1995 Sep 15;52(11):8288-8294. doi: 10.1103/physrevb.52.8288.

No abstract available.

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Aldao CM, Chander M, Goetsch DA, et al. Etching of Si(100)-2 x 1 with chlorine: Reaction pathways, energy anisotropies, and atomic-scale phenomena. Phys Rev B Condens Matter. 1995;52(11):8288-8294doi: 10.1103/physrevb.52.8288.
Aldao, C. M., Chander, M., Goetsch, D. A., & Weaver, J. H. (1995). Etching of Si(100)-2 x 1 with chlorine: Reaction pathways, energy anisotropies, and atomic-scale phenomena. Physical review. B, Condensed matter, 52(11), 8288-8294. https://doi.org/10.1103/physrevb.52.8288
Aldao, et al. "Etching of Si(100)-2 x 1 with chlorine: Reaction pathways, energy anisotropies, and atomic-scale phenomena." Physical review. B, Condensed matter vol. 52,11 (1995): 8288-8294. doi: https://doi.org/10.1103/physrevb.52.8288
Aldao CM, Chander M, Goetsch DA, Weaver JH. Etching of Si(100)-2 x 1 with chlorine: Reaction pathways, energy anisotropies, and atomic-scale phenomena. Phys Rev B Condens Matter. 1995 Sep 15;52(11):8288-8294. doi: 10.1103/physrevb.52.8288. PMID: 9979829.
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Psychosocial stress promotes food intake and enhances the neuroenergetic level in men.

Stress (Amsterdam, Netherlands)

Kistenmacher A, Goetsch J, Ullmann D, Wardzinski EK, Melchert UH, Jauch-Chara K, Oltmanns KM.
PMID: 29969341
Stress. 2018 Nov;21(6):538-547. doi: 10.1080/10253890.2018.1485645. Epub 2018 Jul 03.

Psychosocial stress may lead to increased food consumption and overweight. In turn, obesity is related to reduced brain energy content. We hypothesized that psychosocial stress influencing food intake may alter the neuroenergetic status in the human brain. We tested...

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Kistenmacher A, Goetsch J, Ullmann D, et al. Psychosocial stress promotes food intake and enhances the neuroenergetic level in men. Stress. 2018;21(6):538-547doi: 10.1080/10253890.2018.1485645.
Kistenmacher, A., Goetsch, J., Ullmann, D., Wardzinski, E. K., Melchert, U. H., Jauch-Chara, K., & Oltmanns, K. M. (2018). Psychosocial stress promotes food intake and enhances the neuroenergetic level in men. Stress (Amsterdam, Netherlands), 21(6), 538-547. https://doi.org/10.1080/10253890.2018.1485645
Kistenmacher, Alina, et al. "Psychosocial stress promotes food intake and enhances the neuroenergetic level in men." Stress (Amsterdam, Netherlands) vol. 21,6 (2018): 538-547. doi: https://doi.org/10.1080/10253890.2018.1485645
Kistenmacher A, Goetsch J, Ullmann D, Wardzinski EK, Melchert UH, Jauch-Chara K, Oltmanns KM. Psychosocial stress promotes food intake and enhances the neuroenergetic level in men. Stress. 2018 Nov;21(6):538-547. doi: 10.1080/10253890.2018.1485645. Epub 2018 Jul 03. PMID: 29969341.
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Neuralgic Amyotrophy Presenting with Multifocal Myonecrosis and Rhabdomyolysis.

Cureus

Goetsch MR, Shen J, Jones JA, Memon A, Chatham W.
PMID: 32337110
Cureus. 2020 Mar 23;12(3):e7382. doi: 10.7759/cureus.7382.

Neuralgic amyotrophy (NA), also known as Parsonage-Turner syndrome, is an idiopathic disorder characterized by rapid-onset unilateral upper extremity pain, paralysis, and sensory disturbance in the distribution of the brachial plexus. The etiology is unknown, and there is a multitude...

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Goetsch MR, Shen J, Jones JA, et al. Neuralgic Amyotrophy Presenting with Multifocal Myonecrosis and Rhabdomyolysis. Cureus. 2020;12(3):e7382doi: 10.7759/cureus.7382.
Goetsch, M. R., Shen, J., Jones, J. A., Memon, A., & Chatham, W. (2020). Neuralgic Amyotrophy Presenting with Multifocal Myonecrosis and Rhabdomyolysis. Cureus, 12(3), e7382. https://doi.org/10.7759/cureus.7382
Goetsch, Michael R, et al. "Neuralgic Amyotrophy Presenting with Multifocal Myonecrosis and Rhabdomyolysis." Cureus vol. 12,3 (2020): e7382. doi: https://doi.org/10.7759/cureus.7382
Goetsch MR, Shen J, Jones JA, Memon A, Chatham W. Neuralgic Amyotrophy Presenting with Multifocal Myonecrosis and Rhabdomyolysis. Cureus. 2020 Mar 23;12(3):e7382. doi: 10.7759/cureus.7382. PMID: 32337110; PMCID: PMC7179979.
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Surveillance of SARS-CoV-2 in Frankfurt am Main from October to December 2020 Reveals High Viral Diversity Including Spike Mutation N501Y in B.1.1.70 and B.1.1.7.

Microorganisms

Widera M, Mühlemann B, Corman VM, Toptan T, Beheim-Schwarzbach J, Kohmer N, Schneider J, Berger A, Veith T, Pallas C, Bleicker T, Goetsch U, Tesch J, Gottschalk R, Jones TC, Ciesek S, Drosten C.
PMID: 33918332
Microorganisms. 2021 Apr 02;9(4). doi: 10.3390/microorganisms9040748.

BACKGROUND: International travel is a major driver of the introduction and spread of SARS-CoV-2.AIM: To investigate SARS-CoV-2 genetic diversity in the region of a major transport hub in Germany, we characterized the viral sequence diversity of the SARS-CoV-2 variants...

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Widera M, Mühlemann B, Corman VM, et al. Surveillance of SARS-CoV-2 in Frankfurt am Main from October to December 2020 Reveals High Viral Diversity Including Spike Mutation N501Y in B.1.1.70 and B.1.1.7. Microorganisms. 2021;9(4)doi: 10.3390/microorganisms9040748.
Widera, M., Mühlemann, B., Corman, V. M., Toptan, T., Beheim-Schwarzbach, J., Kohmer, N., Schneider, J., Berger, A., Veith, T., Pallas, C., Bleicker, T., Goetsch, U., Tesch, J., Gottschalk, R., Jones, T. C., Ciesek, S., & Drosten, C. (2021). Surveillance of SARS-CoV-2 in Frankfurt am Main from October to December 2020 Reveals High Viral Diversity Including Spike Mutation N501Y in B.1.1.70 and B.1.1.7. Microorganisms, 9(4), . https://doi.org/10.3390/microorganisms9040748
Widera, Marek, et al. "Surveillance of SARS-CoV-2 in Frankfurt am Main from October to December 2020 Reveals High Viral Diversity Including Spike Mutation N501Y in B.1.1.70 and B.1.1.7." Microorganisms vol. 9,4 (2021). doi: https://doi.org/10.3390/microorganisms9040748
Widera M, Mühlemann B, Corman VM, Toptan T, Beheim-Schwarzbach J, Kohmer N, Schneider J, Berger A, Veith T, Pallas C, Bleicker T, Goetsch U, Tesch J, Gottschalk R, Jones TC, Ciesek S, Drosten C. Surveillance of SARS-CoV-2 in Frankfurt am Main from October to December 2020 Reveals High Viral Diversity Including Spike Mutation N501Y in B.1.1.70 and B.1.1.7. Microorganisms. 2021 Apr 02;9(4). doi: 10.3390/microorganisms9040748. PMID: 33918332; PMCID: PMC8065810.
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[Animal protection law in progress].

ALTEX

Goetschel AF.
PMID: 11178375
ALTEX. 1994;11(3):131-140.

Animal welfare is a very important part of the ethical fundamental order of a Society. The main features of the laws concerning animal welfare are discussed, considering the deficiencies of their execution in Switzerland and Germany. In the following...

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Goetschel AF. Tierschutzrecht im Wandel. Neuere Entwicklung in der Schweiz und der BRD. [Animal protection law in progress]. ALTEX. 1994;11(3):131-140
Goetschel, A. F. (1994). Tierschutzrecht im Wandel. Neuere Entwicklung in der Schweiz und der BRD. [Animal protection law in progress]. ALTEX, 11(3), 131-140.
Goetschel, Antoine F.. "Tierschutzrecht im Wandel. Neuere Entwicklung in der Schweiz und der BRD." [Animal protection law in progress]. ALTEX vol. 11,3 (1994): 131-140.
Goetschel AF. Tierschutzrecht im Wandel. Neuere Entwicklung in der Schweiz und der BRD. [Animal protection law in progress]. ALTEX. 1994;11(3):131-140. PMID: 11178375.
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Effects of dietary tallow level on performance of Alpine does in early lactation.

Small ruminant research : the journal of the International Goat Association

Brown-Crowder IE, Hart SP, Cameron M, Sahlu T, Goetsch AL.
PMID: 11230959
Small Rumin Res. 2001 Mar;39(3):233-241. doi: 10.1016/s0921-4488(00)00197-8.

Sixty Alpine does (initial BW 47+/-1.3kg) were used to determine effects of dietary inclusion of different levels of partially hydrogenated tallow on performance in early lactation (weeks 3-11). Treatments entailed a 30% concentrate, negative control (NC) diet and five...

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Brown-Crowder IE, Hart SP, Cameron M, et al. Effects of dietary tallow level on performance of Alpine does in early lactation. Small Rumin Res. 2001;39(3):233-241doi: 10.1016/s0921-4488(00)00197-8.
Brown-Crowder, I. E., Hart, S. P., Cameron, M., Sahlu, T., & Goetsch, A. L. (2001). Effects of dietary tallow level on performance of Alpine does in early lactation. Small ruminant research : the journal of the International Goat Association, 39(3), 233-241. https://doi.org/10.1016/s0921-4488(00)00197-8
Brown-Crowder, I E., et al. "Effects of dietary tallow level on performance of Alpine does in early lactation." Small ruminant research : the journal of the International Goat Association vol. 39,3 (2001): 233-241. doi: https://doi.org/10.1016/s0921-4488(00)00197-8
Brown-Crowder IE, Hart SP, Cameron M, Sahlu T, Goetsch AL. Effects of dietary tallow level on performance of Alpine does in early lactation. Small Rumin Res. 2001 Mar;39(3):233-241. doi: 10.1016/s0921-4488(00)00197-8. PMID: 11230959.
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Effects of different management practices on preweaning and early postweaning growth of Alpine kids.

Small ruminant research : the journal of the International Goat Association

Goetsch AL, Detweiler G, Sahlu T, Dawson LJ.
PMID: 11445419
Small Rumin Res. 2001 Aug;41(2):109-116. doi: 10.1016/s0921-4488(01)00207-3.

Two sets of 40 dairy goat Alpine kids (3-9 days of age) were used to determine effects of group versus individual pens, preweaning access to forage and different milk feeding restriction regimens on preweaning and early postweaning growth. Treatments...

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Goetsch AL, Detweiler G, Sahlu T, et al. Effects of different management practices on preweaning and early postweaning growth of Alpine kids. Small Rumin Res. 2001;41(2):109-116doi: 10.1016/s0921-4488(01)00207-3.
Goetsch, A. L., Detweiler, G., Sahlu, T., & Dawson, L. J. (2001). Effects of different management practices on preweaning and early postweaning growth of Alpine kids. Small ruminant research : the journal of the International Goat Association, 41(2), 109-116. https://doi.org/10.1016/s0921-4488(01)00207-3
Goetsch, A L., et al. "Effects of different management practices on preweaning and early postweaning growth of Alpine kids." Small ruminant research : the journal of the International Goat Association vol. 41,2 (2001): 109-116. doi: https://doi.org/10.1016/s0921-4488(01)00207-3
Goetsch AL, Detweiler G, Sahlu T, Dawson LJ. Effects of different management practices on preweaning and early postweaning growth of Alpine kids. Small Rumin Res. 2001 Aug;41(2):109-116. doi: 10.1016/s0921-4488(01)00207-3. PMID: 11445419.
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