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A phase II/III randomized study to compare the efficacy and safety of rigosertib plus gemcitabine versus gemcitabine alone in patients with previously untreated metastatic pancreatic cancer.

Annals of oncology : official journal of the European Society for Medical Oncology

O'Neil BH, Scott AJ, Ma WW, Cohen SJ, Aisner DL, Menter AR, Tejani MA, Cho JK, Granfortuna J, Coveler AL, Olowokure OO, Baranda JC, Cusnir M, Phillip P, Boles J, Nazemzadeh R, Rarick M, Cohen DJ, Radford J, Fehrenbacher L, Bajaj R, Bathini V, Fanta P, Berlin J, McRee AJ, Maguire R, Wilhelm F, Maniar M, Jimeno A, Gomes CL, Messersmith WA.
PMID: 26945010
Ann Oncol. 2016 Jun;27(6):1180. doi: 10.1093/annonc/mdw095. Epub 2016 Mar 03.

No abstract available.

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O'Neil BH, Scott AJ, Ma WW, et al. A phase II/III randomized study to compare the efficacy and safety of rigosertib plus gemcitabine versus gemcitabine alone in patients with previously untreated metastatic pancreatic cancer. Ann Oncol. 2016;27(6):1180doi: 10.1093/annonc/mdw095.
O'Neil, B. H., Scott, A. J., Ma, W. W., Cohen, S. J., Aisner, D. L., Menter, A. R., Tejani, M. A., Cho, J. K., Granfortuna, J., Coveler, A. L., Olowokure, O. O., Baranda, J. C., Cusnir, M., Phillip, P., Boles, J., Nazemzadeh, R., Rarick, M., Cohen, D. J., Radford, J., Fehrenbacher, L., Bajaj, R., Bathini, V., Fanta, P., Berlin, J., McRee, A. J., Maguire, R., Wilhelm, F., Maniar, M., Jimeno, A., Gomes, C. L., & Messersmith, W. A. (2016). A phase II/III randomized study to compare the efficacy and safety of rigosertib plus gemcitabine versus gemcitabine alone in patients with previously untreated metastatic pancreatic cancer. Annals of oncology : official journal of the European Society for Medical Oncology, 27(6), 1180. https://doi.org/10.1093/annonc/mdw095
O'Neil, B H, et al. "A phase II/III randomized study to compare the efficacy and safety of rigosertib plus gemcitabine versus gemcitabine alone in patients with previously untreated metastatic pancreatic cancer." Annals of oncology : official journal of the European Society for Medical Oncology vol. 27,6 (2016): 1180. doi: https://doi.org/10.1093/annonc/mdw095
O'Neil BH, Scott AJ, Ma WW, Cohen SJ, Aisner DL, Menter AR, Tejani MA, Cho JK, Granfortuna J, Coveler AL, Olowokure OO, Baranda JC, Cusnir M, Phillip P, Boles J, Nazemzadeh R, Rarick M, Cohen DJ, Radford J, Fehrenbacher L, Bajaj R, Bathini V, Fanta P, Berlin J, McRee AJ, Maguire R, Wilhelm F, Maniar M, Jimeno A, Gomes CL, Messersmith WA. A phase II/III randomized study to compare the efficacy and safety of rigosertib plus gemcitabine versus gemcitabine alone in patients with previously untreated metastatic pancreatic cancer. Ann Oncol. 2016 Jun;27(6):1180. doi: 10.1093/annonc/mdw095. Epub 2016 Mar 03. PMID: 26945010; PMCID: PMC6795379.
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Development and characterisation of highly antibiotic resistant Bartonella bacilliformis mutants.

Scientific reports

Gomes C, Martínez-Puchol S, Ruiz-Roldán L, Pons MJ, Del Valle Mendoza J, Ruiz J.
PMID: 27667026
Sci Rep. 2016 Sep 26;6:33584. doi: 10.1038/srep33584.

The objective was to develop and characterise in vitro Bartonella bacilliformis antibiotic resistant mutants. Three B. bacilliformis strains were plated 35 or 40 times with azithromycin, chloramphenicol, ciprofloxacin or rifampicin discs. Resistance-stability was assessed performing 5 serial passages without...

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Gomes C, Martínez-Puchol S, Ruiz-Roldán L, et al. Development and characterisation of highly antibiotic resistant Bartonella bacilliformis mutants. Sci Rep. 2016;6:33584doi: 10.1038/srep33584.
Gomes, C., Martínez-Puchol, S., Ruiz-Roldán, L., Pons, M. J., Del Valle Mendoza, J., & Ruiz, J. (2016). Development and characterisation of highly antibiotic resistant Bartonella bacilliformis mutants. Scientific reports, 633584. https://doi.org/10.1038/srep33584
Gomes, Cláudia, et al. "Development and characterisation of highly antibiotic resistant Bartonella bacilliformis mutants." Scientific reports vol. 6 (2016): 33584. doi: https://doi.org/10.1038/srep33584
Gomes C, Martínez-Puchol S, Ruiz-Roldán L, Pons MJ, Del Valle Mendoza J, Ruiz J. Development and characterisation of highly antibiotic resistant Bartonella bacilliformis mutants. Sci Rep. 2016 Sep 26;6:33584. doi: 10.1038/srep33584. PMID: 27667026; PMCID: PMC5035977.
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Crystal structures of five 6-mercaptopurine derivatives.

Acta crystallographica. Section E, Crystallographic communications

Gomes LR, Low JN, Magalhães E Silva D, Cagide F, Borges F.
PMID: 27006794
Acta Crystallogr E Crystallogr Commun. 2016 Feb 10;72:307-13. doi: 10.1107/S2056989016001833. eCollection 2016 Mar 01.

The crystal structures of five 6-mercaptopurine derivatives, viz. 2-[(9-acetyl-9H-purin-6-yl)sulfan-yl]-1-(3-meth-oxy-phen-yl)ethan-1-one (1), C16H14N4O3S, 2-[(9-acetyl-9H-purin-6-yl)sulfan-yl]-1-(4-meth-oxy-phen-yl)ethan-1-one (2), C16H14N4O3S, 2-[(9-acetyl-9H-purin-6-yl)sulfan-yl]-1-(4-chloro-phen-yl)ethan-1-one (3), C15H11ClN4O2S, 2-[(9-acetyl-9H-purin-6-yl)sulfan-yl]-1-(4-bromo-phen-yl)ethan-1-one (4), C15H11BrN4O2S, and 1-(3-meth-oxy-phen-yl)-2-[(9H-purin-6-yl)sulfan-yl]ethan-1-one (5), C14H12N4O2S. Compounds (2), (3) and (4) are isomorphous and accordingly their mol-ecular and supra-molecular structures are...

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Gomes LR, Low JN, Magalhães E Silva D, et al. Crystal structures of five 6-mercaptopurine derivatives. Acta Crystallogr E Crystallogr Commun. 2016;72:307-13doi: 10.1107/S2056989016001833.
Gomes, L. R., Low, J. N., Magalhães E Silva, D., Cagide, F., & Borges, F. (2016). Crystal structures of five 6-mercaptopurine derivatives. Acta crystallographica. Section E, Crystallographic communications, 72307-13. https://doi.org/10.1107/S2056989016001833
Gomes, Lígia R, et al. "Crystal structures of five 6-mercaptopurine derivatives." Acta crystallographica. Section E, Crystallographic communications vol. 72 (2016): 307-13. doi: https://doi.org/10.1107/S2056989016001833
Gomes LR, Low JN, Magalhães E Silva D, Cagide F, Borges F. Crystal structures of five 6-mercaptopurine derivatives. Acta Crystallogr E Crystallogr Commun. 2016 Feb 10;72:307-13. doi: 10.1107/S2056989016001833. eCollection 2016 Mar 01. PMID: 27006794; PMCID: PMC4778836.
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Migration and strains induced by different designs of force-closed stems for THA.

Revista brasileira de ortopedia

Griza S, Gomes LS, Cervieri A, Strohaecker TR.
PMID: 27218081
Rev Bras Ortop. 2015 Oct 23;50(6):686-93. doi: 10.1016/j.rboe.2015.09.003. eCollection 2015.

OBJECTIVES: Subtle differences in stem design can result in different mechanical responses of the total hip arthroplasty. Tests measuring migration of the stem relative to the femur, as well as the strains in the cement mantle and on the...

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Griza S, Gomes LS, Cervieri A, et al. Migration and strains induced by different designs of force-closed stems for THA. Rev Bras Ortop. 2015;50(6):686-93doi: 10.1016/j.rboe.2015.09.003.
Griza, S., Gomes, L. S., Cervieri, A., & Strohaecker, T. R. (2015). Migration and strains induced by different designs of force-closed stems for THA. Revista brasileira de ortopedia, 50(6), 686-93. https://doi.org/10.1016/j.rboe.2015.09.003
Griza, Sandro, et al. "Migration and strains induced by different designs of force-closed stems for THA." Revista brasileira de ortopedia vol. 50,6 (2015): 686-93. doi: https://doi.org/10.1016/j.rboe.2015.09.003
Griza S, Gomes LS, Cervieri A, Strohaecker TR. Migration and strains induced by different designs of force-closed stems for THA. Rev Bras Ortop. 2015 Oct 23;50(6):686-93. doi: 10.1016/j.rboe.2015.09.003. eCollection 2015. PMID: 27218081; PMCID: PMC4867916.
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Dichlorodioxomolybdenum(VI) complexes bearing oxygen-donor ligands as olefin epoxidation catalysts.

Dalton transactions (Cambridge, England : 2003)

Oliveira TS, Gomes AC, Lopes AD, Lourenço JP, Almeida Paz FA, Pillinger M, Gonçalves IS.
PMID: 26174418
Dalton Trans. 2015 Aug 21;44(31):14139-48. doi: 10.1039/c5dt02165k.

Treatment of the solvent adduct [MoO2Cl2(THF)2] with either 2 equivalents of N,N-dimethylbenzamide (DMB) or 1 equivalent of N,N'-diethyloxamide (DEO) gave the dioxomolybdenum(vi) complexes [MoO2Cl2(DMB)2] () and [MoO2Cl2(DEO)] (). The molecular structures of and were determined by single-crystal X-ray diffraction....

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Oliveira TS, Gomes AC, Lopes AD, et al. Dichlorodioxomolybdenum(VI) complexes bearing oxygen-donor ligands as olefin epoxidation catalysts. Dalton Trans. 2015;44(31):14139-48doi: 10.1039/c5dt02165k.
Oliveira, T. S., Gomes, A. C., Lopes, A. D., Lourenço, J. P., Almeida Paz, F. A., Pillinger, M., & Gonçalves, I. S. (2015). Dichlorodioxomolybdenum(VI) complexes bearing oxygen-donor ligands as olefin epoxidation catalysts. Dalton transactions (Cambridge, England : 2003), 44(31), 14139-48. https://doi.org/10.1039/c5dt02165k
Oliveira, Tânia S M, et al. "Dichlorodioxomolybdenum(VI) complexes bearing oxygen-donor ligands as olefin epoxidation catalysts." Dalton transactions (Cambridge, England : 2003) vol. 44,31 (2015): 14139-48. doi: https://doi.org/10.1039/c5dt02165k
Oliveira TS, Gomes AC, Lopes AD, Lourenço JP, Almeida Paz FA, Pillinger M, Gonçalves IS. Dichlorodioxomolybdenum(VI) complexes bearing oxygen-donor ligands as olefin epoxidation catalysts. Dalton Trans. 2015 Aug 21;44(31):14139-48. doi: 10.1039/c5dt02165k. PMID: 26174418.
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Higher Caloric Refeeding Is Safe in Hospitalised Adolescent Patients with Restrictive Eating Disorders.

Journal of nutrition and metabolism

Parker EK, Faruquie SS, Anderson G, Gomes L, Kennedy A, Wearne CM, Kohn MR, Clarke SD.
PMID: 27293884
J Nutr Metab. 2016;2016:5168978. doi: 10.1155/2016/5168978. Epub 2016 May 12.

Introduction. This study examines weight gain and assesses complications associated with refeeding hospitalised adolescents with restrictive eating disorders (EDs) prescribed initial calories above current recommendations. Methods. Patients admitted to an adolescent ED structured "rapid refeeding" program for >48 hours...

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Parker EK, Faruquie SS, Anderson G, et al. Higher Caloric Refeeding Is Safe in Hospitalised Adolescent Patients with Restrictive Eating Disorders. J Nutr Metab. 2016;2016:5168978doi: 10.1155/2016/5168978.
Parker, E. K., Faruquie, S. S., Anderson, G., Gomes, L., Kennedy, A., Wearne, C. M., Kohn, M. R., & Clarke, S. D. (2016). Higher Caloric Refeeding Is Safe in Hospitalised Adolescent Patients with Restrictive Eating Disorders. Journal of nutrition and metabolism, 20165168978. https://doi.org/10.1155/2016/5168978
Parker, Elizabeth K, et al. "Higher Caloric Refeeding Is Safe in Hospitalised Adolescent Patients with Restrictive Eating Disorders." Journal of nutrition and metabolism vol. 2016 (2016): 5168978. doi: https://doi.org/10.1155/2016/5168978
Parker EK, Faruquie SS, Anderson G, Gomes L, Kennedy A, Wearne CM, Kohn MR, Clarke SD. Higher Caloric Refeeding Is Safe in Hospitalised Adolescent Patients with Restrictive Eating Disorders. J Nutr Metab. 2016;2016:5168978. doi: 10.1155/2016/5168978. Epub 2016 May 12. PMID: 27293884; PMCID: PMC4880718.
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In Vitro Antileukemic Activity of Xanthosoma sagittifolium (Taioba) Leaf Extract.

Evidence-based complementary and alternative medicine : eCAM

Caxito ML, Correia RR, Gomes AC, Justo G, Coelho MG, Sakuragui CM, Kuster RM, Sabino KC.
PMID: 26180533
Evid Based Complement Alternat Med. 2015;2015:384267. doi: 10.1155/2015/384267. Epub 2015 Jun 09.

Xanthosoma sagittifolium Schott is a herb of the Araceae family, popularly known as taioba, which is consumed as food in some regions of Brazil, Africa, and Asia. This species has already been evaluated for the antifungal activities. However, based...

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Caxito ML, Correia RR, Gomes AC, et al. In Vitro Antileukemic Activity of Xanthosoma sagittifolium (Taioba) Leaf Extract. Evid Based Complement Alternat Med. 2015;2015:384267doi: 10.1155/2015/384267.
Caxito, M. L., Correia, R. R., Gomes, A. C., Justo, G., Coelho, M. G., Sakuragui, C. M., Kuster, R. M., & Sabino, K. C. (2015). In Vitro Antileukemic Activity of Xanthosoma sagittifolium (Taioba) Leaf Extract. Evidence-based complementary and alternative medicine : eCAM, 2015384267. https://doi.org/10.1155/2015/384267
Caxito, Marina L C, et al. "In Vitro Antileukemic Activity of Xanthosoma sagittifolium (Taioba) Leaf Extract." Evidence-based complementary and alternative medicine : eCAM vol. 2015 (2015): 384267. doi: https://doi.org/10.1155/2015/384267
Caxito ML, Correia RR, Gomes AC, Justo G, Coelho MG, Sakuragui CM, Kuster RM, Sabino KC. In Vitro Antileukemic Activity of Xanthosoma sagittifolium (Taioba) Leaf Extract. Evid Based Complement Alternat Med. 2015;2015:384267. doi: 10.1155/2015/384267. Epub 2015 Jun 09. PMID: 26180533; PMCID: PMC4477105.
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Ultrasonographic study and Doppler flow velocimetry of maternal kidneys and liver in low-risk pregnancy.

Radiologia brasileira

Daher CH, Gomes AC, Kobayashi S, Cerri GG, Chammas MC.
PMID: 26185338
Radiol Bras. 2015 May-Jun;48(3):135-42. doi: 10.1590/0100-3984.2013.1822.

OBJECTIVE: Longitudinal study with B-mode ultrasonography and Doppler ultrasonography of maternal kidneys and liver in low-risk pregnancy, to establish and quantify normality parameters, correlating them with physiological changes.MATERIALS AND METHODS: Twenty-five pregnant women were assessed and selected to participate...

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Daher CH, Gomes AC, Kobayashi S, et al. Ultrasonographic study and Doppler flow velocimetry of maternal kidneys and liver in low-risk pregnancy. Radiol Bras. 2015;48(3):135-42doi: 10.1590/0100-3984.2013.1822.
Daher, C. H., Gomes, A. C., Kobayashi, S., Cerri, G. G., & Chammas, M. C. (2015). Ultrasonographic study and Doppler flow velocimetry of maternal kidneys and liver in low-risk pregnancy. Radiologia brasileira, 48(3), 135-42. https://doi.org/10.1590/0100-3984.2013.1822
Daher, Cibele Helena, et al. "Ultrasonographic study and Doppler flow velocimetry of maternal kidneys and liver in low-risk pregnancy." Radiologia brasileira vol. 48,3 (2015): 135-42. doi: https://doi.org/10.1590/0100-3984.2013.1822
Daher CH, Gomes AC, Kobayashi S, Cerri GG, Chammas MC. Ultrasonographic study and Doppler flow velocimetry of maternal kidneys and liver in low-risk pregnancy. Radiol Bras. 2015 May-Jun;48(3):135-42. doi: 10.1590/0100-3984.2013.1822. PMID: 26185338; PMCID: PMC4492564.
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A Critical Review of Mechanical Ventilation Virtual Simulators: Is It Time to Use Them?.

JMIR medical education

Lino JA, Gomes GC, Sousa ND, Carvalho AK, Diniz ME, Viana Junior AB, Holanda MA.
PMID: 27731850
JMIR Med Educ. 2016 Jun 14;2(1):e8. doi: 10.2196/mededu.5350.

BACKGROUND: Teaching mechanical ventilation at the bedside with real patients is difficult with many logistic limitations. Mechanical ventilators virtual simulators (MVVS) may have the potential to facilitate mechanical ventilation (MV) training by allowing Web-based virtual simulation.OBJECTIVE: We aimed to...

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Lino JA, Gomes GC, Sousa ND, et al. A Critical Review of Mechanical Ventilation Virtual Simulators: Is It Time to Use Them?. JMIR Med Educ. 2016;2(1):e8doi: 10.2196/mededu.5350.
Lino, J. A., Gomes, G. C., Sousa, N. D., Carvalho, A. K., Diniz, M. E., Viana Junior, A. B., & Holanda, M. A. (2016). A Critical Review of Mechanical Ventilation Virtual Simulators: Is It Time to Use Them?. JMIR medical education, 2(1), e8. https://doi.org/10.2196/mededu.5350
Lino, Juliana Arcanjo, et al. "A Critical Review of Mechanical Ventilation Virtual Simulators: Is It Time to Use Them?." JMIR medical education vol. 2,1 (2016): e8. doi: https://doi.org/10.2196/mededu.5350
Lino JA, Gomes GC, Sousa ND, Carvalho AK, Diniz ME, Viana Junior AB, Holanda MA. A Critical Review of Mechanical Ventilation Virtual Simulators: Is It Time to Use Them?. JMIR Med Educ. 2016 Jun 14;2(1):e8. doi: 10.2196/mededu.5350. PMID: 27731850; PMCID: PMC5041346.
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Qualitative and quantitative analysis of solar hydrogen generation literature from 2001 to 2014.

Scientometrics

Maghami MR, Asl SN, Rezadad ME, Ale Ebrahim N, Gomes C.
PMID: 26617423
Scientometrics. 2015;105(2):759-771. doi: 10.1007/s11192-015-1730-3. Epub 2015 Sep 09.

Solar hydrogen generation is one of the new topics in the field of renewable energy. Recently, the rate of investigation about hydrogen generation is growing dramatically in many countries. Many studies have been done about hydrogen generation from natural...

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Maghami MR, Asl SN, Rezadad ME, et al. Qualitative and quantitative analysis of solar hydrogen generation literature from 2001 to 2014. Scientometrics. 2015;105(2):759-771doi: 10.1007/s11192-015-1730-3.
Maghami, M. R., Asl, S. N., Rezadad, M. E., Ale Ebrahim, N., & Gomes, C. (2015). Qualitative and quantitative analysis of solar hydrogen generation literature from 2001 to 2014. Scientometrics, 105(2), 759-771. https://doi.org/10.1007/s11192-015-1730-3
Maghami, Mohammad Reza, et al. "Qualitative and quantitative analysis of solar hydrogen generation literature from 2001 to 2014." Scientometrics vol. 105,2 (2015): 759-771. doi: https://doi.org/10.1007/s11192-015-1730-3
Maghami MR, Asl SN, Rezadad ME, Ale Ebrahim N, Gomes C. Qualitative and quantitative analysis of solar hydrogen generation literature from 2001 to 2014. Scientometrics. 2015;105(2):759-771. doi: 10.1007/s11192-015-1730-3. Epub 2015 Sep 09. PMID: 26617423; PMCID: PMC4653236.
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Recharge contribution to the Guarani Aquifer System estimated from the water balance method in a representative watershed.

Anais da Academia Brasileira de Ciencias

Wendland E, Gomes LH, Troeger U.
PMID: 25993364
An Acad Bras Cienc. 2015 Apr-Jun;87(2):595-609. doi: 10.1590/0001-3765201520140062. Epub 2015 May 15.

The contribution of recharge to regional groundwater flow systems is essential information required to establish sustainable water resources management. The objective of this work was to determine the groundwater outflow in the Ribeirão da Onça Basin using a water...

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Wendland E, Gomes LH, Troeger U. Recharge contribution to the Guarani Aquifer System estimated from the water balance method in a representative watershed. An Acad Bras Cienc. 2015;87(2):595-609doi: 10.1590/0001-3765201520140062.
Wendland, E., Gomes, L. H., & Troeger, U. (2015). Recharge contribution to the Guarani Aquifer System estimated from the water balance method in a representative watershed. Anais da Academia Brasileira de Ciencias, 87(2), 595-609. https://doi.org/10.1590/0001-3765201520140062
Wendland, Edson, et al. "Recharge contribution to the Guarani Aquifer System estimated from the water balance method in a representative watershed." Anais da Academia Brasileira de Ciencias vol. 87,2 (2015): 595-609. doi: https://doi.org/10.1590/0001-3765201520140062
Wendland E, Gomes LH, Troeger U. Recharge contribution to the Guarani Aquifer System estimated from the water balance method in a representative watershed. An Acad Bras Cienc. 2015 Apr-Jun;87(2):595-609. doi: 10.1590/0001-3765201520140062. Epub 2015 May 15. PMID: 25993364.
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Leishmania donovani Nucleoside Hydrolase Terminal Domains in Cross-Protective Immunotherapy Against Leishmania amazonensis Murine Infection.

Frontiers in immunology

Nico D, Gomes DC, Palatnik-de-Sousa I, Morrot A, Palatnik M, Palatnik-de-Sousa CB.
PMID: 24966857
Front Immunol. 2014 Jun 11;5:273. doi: 10.3389/fimmu.2014.00273. eCollection 2014.

Nucleoside hydrolases of the Leishmania genus are vital enzymes for the replication of the DNA and conserved phylogenetic markers of the parasites. Leishmania donovani nucleoside hydrolase (NH36) induced a main CD4(+) T cell driven protective response against L. chagasi...

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Nico D, Gomes DC, Palatnik-de-Sousa I, et al. Leishmania donovani Nucleoside Hydrolase Terminal Domains in Cross-Protective Immunotherapy Against Leishmania amazonensis Murine Infection. Front Immunol. 2014;5:273doi: 10.3389/fimmu.2014.00273.
Nico, D., Gomes, D. C., Palatnik-de-Sousa, I., Morrot, A., Palatnik, M., & Palatnik-de-Sousa, C. B. (2014). Leishmania donovani Nucleoside Hydrolase Terminal Domains in Cross-Protective Immunotherapy Against Leishmania amazonensis Murine Infection. Frontiers in immunology, 5273. https://doi.org/10.3389/fimmu.2014.00273
Nico, Dirlei, et al. "Leishmania donovani Nucleoside Hydrolase Terminal Domains in Cross-Protective Immunotherapy Against Leishmania amazonensis Murine Infection." Frontiers in immunology vol. 5 (2014): 273. doi: https://doi.org/10.3389/fimmu.2014.00273
Nico D, Gomes DC, Palatnik-de-Sousa I, Morrot A, Palatnik M, Palatnik-de-Sousa CB. Leishmania donovani Nucleoside Hydrolase Terminal Domains in Cross-Protective Immunotherapy Against Leishmania amazonensis Murine Infection. Front Immunol. 2014 Jun 11;5:273. doi: 10.3389/fimmu.2014.00273. eCollection 2014. PMID: 24966857; PMCID: PMC4052736.
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