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Showing 1 to 12 of 425 entries
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Crystal structures of five 6-mercaptopurine derivatives.

Acta crystallographica. Section E, Crystallographic communications

Gomes LR, Low JN, Magalhães E Silva D, Cagide F, Borges F.
PMID: 27006794
Acta Crystallogr E Crystallogr Commun. 2016 Feb 10;72:307-13. doi: 10.1107/S2056989016001833. eCollection 2016 Mar 01.

The crystal structures of five 6-mercaptopurine derivatives, viz. 2-[(9-acetyl-9H-purin-6-yl)sulfan-yl]-1-(3-meth-oxy-phen-yl)ethan-1-one (1), C16H14N4O3S, 2-[(9-acetyl-9H-purin-6-yl)sulfan-yl]-1-(4-meth-oxy-phen-yl)ethan-1-one (2), C16H14N4O3S, 2-[(9-acetyl-9H-purin-6-yl)sulfan-yl]-1-(4-chloro-phen-yl)ethan-1-one (3), C15H11ClN4O2S, 2-[(9-acetyl-9H-purin-6-yl)sulfan-yl]-1-(4-bromo-phen-yl)ethan-1-one (4), C15H11BrN4O2S, and 1-(3-meth-oxy-phen-yl)-2-[(9H-purin-6-yl)sulfan-yl]ethan-1-one (5), C14H12N4O2S. Compounds (2), (3) and (4) are isomorphous and accordingly their mol-ecular and supra-molecular structures are...

Epidemiology of foot and mouth disease in Karnataka state, India: a retrospective study.

Virusdisease

Hegde R, Gomes AR, Giridhar P, Kowalli S, Shivashankar BP, Sudharshana KJ, Nagaraj K, Sesharao R, Mallinath KC, Shankar BP, Nagaraj D, Seema CM, Khan TA, Nagaraj GV, Srikala K, Dharanesh NK, Venkatesha MD, Renukaprasad C.
PMID: 25674631
Virusdisease. 2014 Dec;25(4):504-9. doi: 10.1007/s13337-014-0239-3. Epub 2014 Nov 12.

A retrospective study on the epidemiology of foot and- mouth disease (FMD) in Karnataka, India between the years 1977 and 2012-13 based on the data collected through passive and active surveillance was undertaken. A total of 11,159 outbreaks with...

Morphologic study of different treatments for gastrocnemius muscle contusion in rats.

Revista brasileira de ortopedia

Macedo AC, Ywazaki JL, Macedo RM, Noronha L, Gomes AR.
PMID: 28050543
Rev Bras Ortop. 2016 Oct 15;51(6):697-706. doi: 10.1016/j.rboe.2016.10.001. eCollection 2016.

OBJECTIVE: Evaluate the effects of ultrasound and stretching in morphology after rat muscle contusion.METHODS: Male Wistar rats (RESULTS: The final body weight was higher than the initial in all groups. The number of sarcomeres was statistically higher in LSG...

Role of gemcitabine as second-line therapy after progression on FOLFIRINOX in advanced pancreatic cancer: a retrospective analysis.

Journal of gastrointestinal oncology

da Rocha Lino A, Abrahão CM, Brandão RM, Gomes JR, Ferrian AM, Machado MC, Buzaid AC, Maluf FC, Peixoto RD.
PMID: 26487945
J Gastrointest Oncol. 2015 Oct;6(5):511-5. doi: 10.3978/j.issn.2078-6891.2015.041.

BACKGROUND: Cancer of the exocrine pancreas is a highly lethal malignancy. Surgical resection is the only potentially curative treatment. Unfortunately, because of the late presentation, the majority have either locally advanced cancer at initial diagnosis. Systemic chemotherapy provides benefit...

Erratum: The metabolic co-regulator PGC1α suppresses prostate cancer metastasis.

Nature cell biology

Torrano V, Valcarcel-Jimenez L, Cortazar AR, Liu X, Urosevic J, Castillo-Martin M, Fernández-Ruiz S, Morciano G, Caro-Maldonado A, Guiu M, Zúñiga-García P, Graupera M, Bellmunt A, Pandya P, Lorente M, Martín-Martín N, Sutherland JD, Sanchez-Mosquera P, Bozal-Basterra L, Zabala-Letona A, Arruabarrena-Aristorena A, Berenguer A, Embade N, Ugalde-Olano A, Lacasa-Viscasillas I, Loizaga-Iriarte A, Unda-Urzaiz M, Schultz N, Aransay AM, Sanz-Moreno V, Barrio R, Velasco G, Pinton P, Cordon-Cardo C, Locasale JW, Gomis RR, Carracedo A.
PMID: 28659639
Nat Cell Biol. 2017 Jun 29;19(7):873. doi: 10.1038/ncb3558.

This corrects the article DOI: 10.1038/ncb3357.

Role of routine pre-operative screening venous duplex ultrasound in morbidly obese patients undergoing bariatric surgery.

Journal of minimal access surgery

Raj PP, Gomes RM, Kumar S, Senthilnathan P, Parathasarathi R, Rajapandian S, Palanivelu C.
PMID: 28607288
J Minim Access Surg. 2017 Jul-Sep;13(3):205-207. doi: 10.4103/jmas.JMAS_199_15.

BACKGROUND/AIMS: It is well established that obesity is a strongly associated risk factor for post-operative deep vein thrombosis (DVT). Physical effects and pro-thrombotic, pro-inflammatory and hypofibrinolytic effects of severe obesity may predispose to idiopathic DVT (pre-operatively) because of which...

Continuous hydrothermal synthesis of Ca.

Journal of colloid and interface science

Clark I, Dunne PW, Gomes RL, Lester E.
PMID: 28605712
J Colloid Interface Sci. 2017 Oct 15;504:492-499. doi: 10.1016/j.jcis.2017.05.105. Epub 2017 May 27.

Continuous hydrothermal synthesis (CHS) of nanoparticles is most commonly associated with the production of metal oxides and ceramics. However, recent work has demonstrated that layered double hydroxides (LDH) can also be synthesised via this method. This research investigates how...

HOLMES: The electron capture decay of [Formula: see text]Ho to measure the electron neutrino mass with sub-eV sensitivity.

The European physical journal. C, Particles and fields

Alpert B, Balata M, Bennett D, Biasotti M, Boragno C, Brofferio C, Ceriale V, Corsini D, Day PK, De Gerone M, Dressler R, Faverzani M, Ferri E, Fowler J, Gatti F, Giachero A, Hays-Wehle J, Heinitz S, Hilton G, Köster U, Lusignoli M, Maino M, Mates J, Nisi S, Nizzolo R, Nucciotti A, Pessina G, Pizzigoni G, Puiu A, Ragazzi S, Reintsema C, Gomes MR, Schmidt D, Schumann D, Sisti M, Swetz D, Terranova F, Ullom J.
PMID: 25995704
Eur Phys J C Part Fields. 2015;75(3):112. doi: 10.1140/epjc/s10052-015-3329-5. Epub 2015 Mar 10.

The European Research Council has recently funded HOLMES, a new experiment to directly measure the neutrino mass. HOLMES will perform a calorimetric measurement of the energy released in the decay of [Formula: see text]Ho. The calorimetric measurement eliminates systematic...

Preclinical and Clinical Studies for Sodium Tungstate: Application in Humans.

Journal of clinical & cellular immunology

Bertinat R, Nualart F, Li X, Yáñez AJ, Gomis R.
PMID: 25995968
J Clin Cell Immunol. 2015 Feb;6(1). doi: 10.4172/2155-9899.1000285.

Diabetes is a complex metabolic disorder triggered by the deficient secretion of insulin by the pancreatic β-cell or the resistance of peripheral tissues to the action of the hormone. Chronic hyperglycemia is the major consequence of this failure, and...

BRCA1 positively regulates FOXO3 expression by restricting FOXO3 gene methylation and epigenetic silencing through targeting EZH2 in breast cancer.

Oncogenesis

Gong C, Yao S, Gomes AR, Man EP, Lee HJ, Gong G, Chang S, Kim SB, Fujino K, Kim SW, Park SK, Lee JW, Lee MH, Khoo US, Lam EW.
PMID: 27043660
Oncogenesis. 2016 Apr 04;5:e214. doi: 10.1038/oncsis.2016.23.

BRCA1 mutation or depletion correlates with basal-like phenotype and poor prognosis in breast cancer but the underlying reason remains elusive. RNA and protein analysis of a panel of breast cancer cell lines revealed that BRCA1 deficiency is associated with...

Corrigendum: Hypothalamic miRNAs: emerging roles in energy balance control.

Frontiers in neuroscience

Schneeberger M, Gómez-Valadés AG, Ramírez S, Gomis R, Claret M.
PMID: 25852465
Front Neurosci. 2015 Mar 20;9:96. doi: 10.3389/fnins.2015.00096. eCollection 2015.

[This corrects the article on p. 41 in vol. 9, PMID: 25729348.].

Cutaneous Cryptococcoma in a Patient on TNF-α Inhibition.

Journal of clinical medicine

Gomes RM, Cerio DR, Loghmanee C, McKinney J, Patel M, Miraglia J, Yousef-Bessler M, Zippin JH, Schuetz AN, Pinho PB.
PMID: 26237147
J Clin Med. 2013 Nov 22;2(4):260-3. doi: 10.3390/jcm2040260.

An 87-year old Caucasian male with past medical history of rheumatoid arthritis (RA) and chronic kidney disease presents with left hand erythema, pain, tenderness, induration and edema. Clinically, these hand findings began proximal to the metacarpo-phalangeal joints and extended...

Showing 1 to 12 of 425 entries