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Mental Health Service Provision in Low- and Middle-Income Countries.

Health services insights

Rathod S, Pinninti N, Irfan M, Gorczynski P, Rathod P, Gega L, Naeem F.
PMID: 28469456
Health Serv Insights. 2017 Mar 28;10:1178632917694350. doi: 10.1177/1178632917694350. eCollection 2017.

This article discusses the provision of mental health services in low- and middle-income countries (LMICs) with a view to understanding the cultural dynamics-how the challenges they pose can be addressed and the opportunities harnessed in specific cultural contexts. The...

Molecular gas dynamics observations of Chapman-Enskog behavior and departures there from in nonequilibrium gases.

Physical review. E, Statistical, nonlinear, and soft matter physics

Gallis MA, Torczynski JR, Rader DJ.
PMID: 15169048
Phys Rev E Stat Nonlin Soft Matter Phys. 2004 Apr;69(4):042201. doi: 10.1103/PhysRevE.69.042201. Epub 2004 Apr 29.

Bird's direct simulation Monte Carlo method is used to compute the molecular velocity distribution of a gas with heat flow. At continuum nonequilibrium conditions (small heat flux), Chapman-Enskog behavior is obtained for inverse-power-law molecules (hard-sphere through Maxwell): the Sonine-polynomial...

Analgesia and addiction in emergency department patients with acute pain exacerbations.

The California journal of emergency medicine

Gorchynski J, Kelly K.
PMID: 20847859
Cal J Emerg Med. 2005 Jan;6(1):3-8.

INTRODUCTION: There is ongoing controversy regarding the appropriate use of narcotic analgesia for patients presenting frequently to the emergency department (ED) with subjective acute exacerbations of pain. "Are we treating pain or enabling addiction?"OBJECTIVES: To determine whether the presence...

Parameters of Reserpine Analogs That Induce MSH2/MSH6-Dependent Cytotoxic Response.

Journal of nucleic acids

Vasilyeva A, Clodfelter JE, Gorczynski MJ, Gerardi AR, King SB, Salsbury F, Scarpinato KD.
PMID: 20936178
J Nucleic Acids. 2010 Sep 13;2010. doi: 10.4061/2010/162018.

Mismatch repair proteins modulate the cytotoxicity of several chemotherapeutic agents. We have recently proposed a "death conformation" of the MutS homologous proteins that is distinguishable from their "repair conformation." This conformation can be induced by a small molecule, reserpine,...

An experimental assembly for precise measurement of thermal accommodation coefficients.

The Review of scientific instruments

Trott WM, Castañeda JN, Torczynski JR, Gallis MA, Rader DJ.
PMID: 21456801
Rev Sci Instrum. 2011 Mar;82(3):035120. doi: 10.1063/1.3571269.

An experimental apparatus has been developed to determine thermal accommodation coefficients for a variety of gas-surface combinations. Results are obtained primarily through measurement of the pressure dependence of the conductive heat flux between parallel plates separated by a gas-filled...

Under Utilization of local anesthetics in infant lumbar punctures.

The western journal of emergency medicine

Gorchynski J, Everett W, Prebil L.
PMID: 19561696
West J Emerg Med. 2008 Jan;9(1):9-12.

BACKGROUND: Lumbar Puncture (LP) is an invasive procedure frequently used to diagnose meningitis among the pediatric population. Neonates and infants have not routinely received local anesthesia prior to LP.STUDY OBJECTIVE: To determine whether emergency medicine physicians and pediatricians use...

The routine utilization of procedural pain management for pediatric lumbar punctures: are we there yet?.

Journal of clinical medicine research

Gorchynski J, McLaughlin T.
PMID: 22121399
J Clin Med Res. 2011 Jul 26;3(4):164-7. doi: 10.4021/jocmr584w.

BACKGROUND: The objective of this study was to assess the utilization of local anesthetics by emergency physicians (EP) and pediatric physicians (PP) who performed a lumbar puncture (LP) in pediatric patients from birth to 24 months of age.METHODS: We...

CD200fc enhances anti-tumoral immune response and inhibits visceral metastasis of breast carcinoma.

Oncotarget

Erin N, Tanrıöver G, Curry A, Akman M, Duymuş Ö, Gorczynski R.
PMID: 29721190
Oncotarget. 2018 Apr 10;9(27):19147-19158. doi: 10.18632/oncotarget.24931. eCollection 2018 Apr 10.

CD200 is a widely expressed cell surface glycoprotein that inhibits excessive inflammation in autoimmunity, transplantation, and viral infections. We previously observed that visceral metastasis of highly aggressive and inflammatory 4THM breast carcinoma cells was markedly decreased in CD200 transgenic...

Checkpoint blockade in solid tumors and B-cell malignancies, with special consideration of the role of CD200.

Cancer management and research

Gorczynski RM, Zhu F.
PMID: 29180896
Cancer Manag Res. 2017 Nov 13;9:601-609. doi: 10.2147/CMAR.S147326. eCollection 2017.

In the ontogeny of a normal immune response, a series of checkpoints must be overcome to ensure that unwanted and/or harmful self-directed activation responses are avoided. Many of the molecules now known to be active in this overseeing of...

Contemporary oncology (Poznan, Poland)

Kunc M, Gabrych A, Rekawiecki B, Gorczynski A, Franke S, Haybaeck J, Biernat W, Czapiewski P.
PMID: 31992951
Contemp Oncol (Pozn). 2019;23(4):202-207. doi: 10.5114/wo.2019.89635. Epub 2019 Nov 07.

INTRODUCTION: Carcinosarcoma (CS) is an infrequent neoplasm composed of a carcinomatous and a sarcomatous element. Its molecular pathogenesis is poorly understood. In this study, we investigated the disturbances in the immunohistochemical expression of p53 and mismatch repair (MMR) proteins,...

Correction to: 'Tropical mammal functional diversity increases with productivity but decreases with anthropogenic disturbance'.

Proceedings. Biological sciences

Gorczynski D, Hsieh C, Luciano JT, Ahumada J, Espinosa S, Johnson S, Rovero F, Santos F, Andrianarisoa MH, Astaiza JH, Jansen PA, Kayijamahe C, Moreira Lima MG, Salvador J, Beaudrot L.
PMID: 33726602
Proc Biol Sci. 2021 Mar 31;288(1947):20210432. doi: 10.1098/rspb.2021.0432. Epub 2021 Mar 17.

No abstract available.

Fluorescence spectroscopy and multivariate spectral descriptor analysis for high-throughput multiparameter optimization of polymerization conditions of combinatorial 96-microreactor arrays.

Journal of combinatorial chemistry

Potyrailo RA, Wroczynski RJ, Lemmon JP, Flanagan WP, Siclovan OP.
PMID: 12523829
J Comb Chem. 2003 Jan-Feb;5(1):8-17. doi: 10.1021/cc020062g.

Selection of optimum process conditions in combinatorial microreactors is essential if the combinatorial synthesis process is to be correlated with the synthesis process on a more conventional scale and the materials are to have the desired chemical properties. We...

Showing 1 to 12 of 60 entries