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Showing 1 to 12 of 25 entries
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Cytokines in bipolar disorder: recent findings, deleterious effects but promise for future therapeutics.

CNS spectrums

Brietzke E, Stabellini R, Grassi-Oliveira R, Lafer B.
PMID: 24725501
CNS Spectr. 2011 Jul;16(7):157-68. doi: 10.1017/S1092852912000338.

An emerging body of evidence points to impairments in neuroplasticity, cell resilience, and neuronal survival as major pathophysiological mechanisms in bipolar disorder. Neuronal survival is influenced by several factors including an orchestrated action of neurotransmitters, hormones, and neurotrophins. Patients...

Editorial: Executive Functions in Psychiatric Disorders.

Frontiers in psychology

Malloy-Diniz LF, Miranda DM, Grassi-Oliveira R.
PMID: 28928684
Front Psychol. 2017 Sep 05;8:1461. doi: 10.3389/fpsyg.2017.01461. eCollection 2017.

No abstract available.

Comparative Evaluation of Bone Repair with Four Different Bone Substitutes in Critical Size Defects.

International journal of biomaterials

Grossi-Oliveira G, Faverani LP, Mendes BC, Braga Polo TO, Batista Mendes GC, de Lima VN, Ribeiro Júnior PD, Okamoto R, Magro-Filho O.
PMID: 32528537
Int J Biomater. 2020 May 23;2020:5182845. doi: 10.1155/2020/5182845. eCollection 2020.

This study evaluated the osteoconductive potential of four biomaterials used to fill bone defects. For this, 24 male Albino rabbits were submitted to the creation of a bilateral 8 mm calvarial bone defect. The animals were divided into four...

Childhood maltreatment and executive functions in adolescents.

Child and adolescent mental health

Mothes L, Kristensen CH, Grassi-Oliveira R, Fonseca RP, de Lima Argimon II, Irigaray TQ.
PMID: 32680329
Child Adolesc Ment Health. 2015 Feb;20(1):56-62. doi: 10.1111/camh.12068. Epub 2014 Jun 06.

BACKGROUND: The aim of this study was to investigate differences in executive functions between adolescents exposed to different forms of single- and multitype childhood maltreatment.METHOD: The sample was composed of 83 adolescents, divided into three groups: single-type maltreatment (n...

Early environmental enrichment rescues memory impairments provoked by mild neonatal hypoxia-ischemia in adolescent mice.

Behavioural brain research

Orso R, Creutzberg KC, Lumertz FS, Wearick-Silva LE, Sanches EF, Mestriner RG, Wegener G, Grassi-Oliveira R.
PMID: 33798820
Behav Brain Res. 2021 Jun 11;407:113237. doi: 10.1016/j.bbr.2021.113237. Epub 2021 Mar 31.

Hypoxia-ischemia (HI) is a consequence of a lack of oxygen and glucose support to the developing brain, which causes several neurodevelopmental impairments. Environmental enrichment (EE) is considered an option to recover the alterations observed in rodents exposed to HI....

Decision-making under risk and theory of mind in adolescent offenders in provisional deprivation of liberty.

Trends in psychiatry and psychotherapy

Loureiro RJ, Kataoka FT, Viola TW, Vargas GI, Sanvicente-Vieira B, Grassi-Oliveira R, Kluwe-Schiavon B.
PMID: 34758266
Trends Psychiatry Psychother. 2021 Nov 10; doi: 10.47626/2237-6089-2020-0155. Epub 2021 Nov 10.

INTRODUCTION: Delinquent behaviors are risky behaviors that increase during puberty and reach the highest peak in late adolescence. It has been proposed that poor decision-making and theory of mind (ToM) are key cognitive processes implicated with delinquency during adolescence,...

Exposure to Prenatal Stress Is Associated With an Excitatory/Inhibitory Imbalance in Rat Prefrontal Cortex and Amygdala and an Increased Risk for Emotional Dysregulation.

Frontiers in cell and developmental biology

Marchisella F, Creutzberg KC, Begni V, Sanson A, Wearick-Silva LE, Tractenberg SG, Orso R, Kestering-Ferreira É, Grassi-Oliveira R, Riva MA.
PMID: 34141707
Front Cell Dev Biol. 2021 Jun 01;9:653384. doi: 10.3389/fcell.2021.653384. eCollection 2021.

Epidemiological studies have shown that environmental insults and maternal stress during pregnancy increase the risk of several psychiatric disorders in the offspring. Converging lines of evidence from humans, as well as from rodent models, suggest that prenatal stress (PNS)...

Long-term Effects of Maternal Separation on Anxiety-Like Behavior and Neuroendocrine Parameters in Adult Balb/c Mice.

Chronic stress (Thousand Oaks, Calif.)

Kestering-Ferreira E, Tractenberg SG, Lumertz FS, Orso R, Creutzberg KC, Wearick-Silva LE, Viola TW, Grassi-Oliveira R.
PMID: 34993376
Chronic Stress (Thousand Oaks). 2021 Dec 21;5:24705470211067181. doi: 10.1177/24705470211067181. eCollection 2021.

No abstract available.

Oxytocin Receptor Exon III Methylation in the Umbilical Cord Blood of Newborns With Prenatal Exposure to Crack Cocaine.

Frontiers in cell and developmental biology

Baptista T, de Azeredo LA, Zaparte A, Viola TW, Coral SC, Nagai MA, Mangone FR, Pavanelli AC, Schuch JB, Mardini V, Szobot CM, Grassi-Oliveira R.
PMID: 34178979
Front Cell Dev Biol. 2021 Jun 04;9:639287. doi: 10.3389/fcell.2021.639287. eCollection 2021.

BACKGROUND: Prenatal cocaine exposure (PCE) is associated with behavioral, cognitive, and social consequences in children that might persist into later development. However, there are still few data concerning epigenetic mechanisms associated with the effects of gestational cocaine exposure, particularly...

Inflammation, neurotrophism and oxidative stress and childhood psychopathology in a large community sample.

Acta psychiatrica Scandinavica

Cunha GR, Asevedo E, Mansur RB, Zugman A, Pan PM, Gadelha A, Belangero SI, Rizzo LB, Coelho R, Stertz L, Cogo-Moreira H, Grassi-Oliveira R, Teixeira AL, Kauer-Sant'Anna M, Mari JJ, Miguel EC, Bressan RA, Brietzke E.
PMID: 26139469
Acta Psychiatr Scand. 2016 Feb;133(2):122-132. doi: 10.1111/acps.12453. Epub 2015 Jul 03.

OBJECTIVE: To investigate the association between peripheral biomarkers and child psychopathology in a large community sample.METHOD: A total of 625 aged 6- to 13-year old subjects were recruited from a community school-based study. Psychopathology was assessed using the Child...

Corticotropin Releasing Factor in the Bed Nucleus of the Stria Terminalis in Socially Defeated and Non-stressed Mice with a History of Chronic Alcohol Intake.

Frontiers in pharmacology

Albrechet-Souza L, Viola TW, Grassi-Oliveira R, Miczek KA, de Almeida RMM.
PMID: 29118713
Front Pharmacol. 2017 Oct 25;8:762. doi: 10.3389/fphar.2017.00762. eCollection 2017.

Stress exposure has been identified as one risk factor for alcohol abuse that may facilitate the transition from social or regulated use to the development of alcohol dependence. Preclinical studies have shown that dysregulation of the corticotropin releasing factor...

Features of Immunosenescence in Women Newly Diagnosed With Breast Cancer.

Frontiers in immunology

Trintinaglia L, Bandinelli LP, Grassi-Oliveira R, Petersen LE, Anzolin M, Correa BL, Schuch JB, Bauer ME.
PMID: 30061900
Front Immunol. 2018 Jul 16;9:1651. doi: 10.3389/fimmu.2018.01651. eCollection 2018.

Adults exposed to childhood maltreatment have increased stress reactivity. This profile is associated with dysregulation of the immune system, including enhanced inflammatory reactions and accelerated senescence. Subjects exposed to ear stress have increased risk for several age-related diseases, including...

Showing 1 to 12 of 25 entries