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Showing 1 to 12 of 23 entries
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LncRNAs LY86-AS1 and VIM-AS1 Distinguish Plasma Cell Leukemia Patients from Multiple Myeloma Patients.

Biomedicines

Bútová R, Vychytilová-Faltejsková P, Gregorová J, Radová L, Almáši M, Bezděková R, Brožová L, Jarkovský J, Knechtová Z, Štork M, Pour L, Ševčíková S.
PMID: 34829867
Biomedicines. 2021 Nov 08;9(11). doi: 10.3390/biomedicines9111637.

Long non-coding RNAs (lncRNAs) are functional RNAs longer than 200 nucleotides. Due to modern genomic techniques, the involvement of lncRNAs in tumorigenesis has been revealed; however, information concerning lncRNA interplay in multiple myeloma (MM) and plasma cell leukemia (PCL)...

Waldenström macroglobulinemia.

Klinicka onkologie : casopis Ceske a Slovenske onkologicke spolecnosti

Baďurová K, Gregorová J, Vlachová M, Krejčí M, Ševčíková S.
PMID: 34911327
Klin Onkol. 2021;34(6):428-433. doi: 10.48095/ccko2021428.

BACKGROUND: Waldenström macroglobulinemia (WM) is a hematological malignancy; it is a monoclonal gammopathy, a disease characterized by presence of a monoclonal immunoglobulin in serum and/or urine. The median age at dia-gnosis is 71 years. WM is not an aggres-sive...

Microstructural, Mechanical, Corrosion and Cytotoxicity Characterization of Porous Ti-Si Alloys with Pore-Forming Agent.

Materials (Basel, Switzerland)

Školáková A, Körberová J, Málek J, Rohanová D, Jablonská E, Pinc J, Salvetr P, Gregorová E, Novák P.
PMID: 33316967
Materials (Basel). 2020 Dec 09;13(24). doi: 10.3390/ma13245607.

Titanium and its alloys belong to the group of materials used in implantology due to their biocompatibility, outstanding corrosion resistance and good mechanical properties. However, the value of Young's modulus is too high in comparison with the human bone,...

Segmental trisomy of mouse chromosome 17: introducing an alternative model of Down's syndrome.

Comparative and functional genomics

Forejt J, Vacík T, Gregorová S.
PMID: 18629032
Comp Funct Genomics. 2003;4(6):647-52. doi: 10.1002/cfg.334.

All of the mouse models of human trisomy 21 syndrome that have been studied so far are based on segmental trisomies, encompassing, to a varying extent, distal chromosome 16. Their comparison with one or more unrelated and non-overlapping segmental...

Standardization of clinical pharmacist's activities: Methodology.

Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society

Gregorová J, Rychlíčková J, Šaloun J.
PMID: 28951680
Saudi Pharm J. 2017 Sep;25(6):927-933. doi: 10.1016/j.jsps.2017.02.005. Epub 2017 Feb 14.

STUDY OBJECTIVES: Establishing standardized and controlled system of work at a clinical pharmacy department and establishing effective recording of activities of a group of four clinical pharmacist when providing clinical pharmaceutical care (CPC) in a hospital.METHODS: The duration of...

Erdheim-Chester disease.

Klinicka onkologie : casopis Ceske a Slovenske onkologicke spolecnosti

Brychtová M, Vlachová M, Gregorová J, Krejčí M, Adam Z, Ševčíková S.
PMID: 34911328
Klin Onkol. 2021;34(6):434-439. doi: 10.48095/ccko2021434.

Erdheim-Chester disease is a rare inflammatory myeloid clonal disease which is classified into histiocytoses. It is characterized by excessive production and accumulation of foamy histiocytes and Touton giant cells in various tissues and organs. Foamy histiocytes and Touton giant...

Broad-range RNA modification analysis of complex biological samples using rapid C18-UPLC-MS.

RNA biology

Gregorova P, Sipari NH, Sarin LP.
PMID: 33356826
RNA Biol. 2021 Oct;18(10):1382-1389. doi: 10.1080/15476286.2020.1853385. Epub 2020 Dec 23.

Post-transcriptional RNA modifications play an important role in cellular metabolism with homoeostatic disturbances manifesting as a wide repertoire of phenotypes, reduced stress tolerance and translational perturbation, developmental defects, and diseases, such as type II diabetes, leukaemia, and carcinomas. Hence,...

Data-Dependent Conditional Priors for Unsupervised Learning of Multimodal Data.

Entropy (Basel, Switzerland)

Lavda F, Gregorová M, Kalousis A.
PMID: 33286658
Entropy (Basel). 2020 Aug 13;22(8). doi: 10.3390/e22080888.

One of the major shortcomings of variational autoencoders is the inability to produce generations from the individual modalities of data originating from mixture distributions. This is primarily due to the use of a simple isotropic Gaussian as the prior...

Broad-range RNA modification analysis of complex biological samples using rapid C18-UPLC-MS.

RNA biology

Gregorova P, Sipari NH, Sarin LP.
PMID: 33356826
RNA Biol. 2021 Oct;18(10):1382-1389. doi: 10.1080/15476286.2020.1853385. Epub 2020 Dec 23.

Post-transcriptional RNA modifications play an important role in cellular metabolism with homoeostatic disturbances manifesting as a wide repertoire of phenotypes, reduced stress tolerance and translational perturbation, developmental defects, and diseases, such as type II diabetes, leukaemia, and carcinomas. Hence,...

The comprehensive interactomes of human adenosine RNA methyltransferases and demethylases reveal distinct functional and regulatory features.

Nucleic acids research

Covelo-Molares H, Obrdlik A, Poštulková I, Dohnálková M, Gregorová P, Ganji R, Potěšil D, Gawriyski L, Varjosalo M, Vaňáčová Š.
PMID: 34634806
Nucleic Acids Res. 2021 Nov 08;49(19):10895-10910. doi: 10.1093/nar/gkab900.

N6-methyladenosine (m6A) and N6,2'-O-dimethyladenosine (m6Am) are two abundant modifications found in mRNAs and ncRNAs that can regulate multiple aspects of RNA biology. They function mainly by regulating interactions with specific RNA-binding proteins. Both modifications are linked to development, disease...

Modulatory Effects of Eschscholzia californica Alkaloids on Recombinant GABAA Receptors.

Biochemistry research international

Fedurco M, Gregorová J, Šebrlová K, Kantorová J, Peš O, Baur R, Sigel E, Táborská E.
PMID: 26509084
Biochem Res Int. 2015;2015:617620. doi: 10.1155/2015/617620. Epub 2015 Oct 05.

The California poppy (Eschscholzia californica Cham.) contains a variety of natural compounds including several alkaloids found exclusively in this plant. Because of the sedative, anxiolytic, and analgesic effects, this herb is currently sold in pharmacies in many countries. However,...

Fast quantification of whisky lactone in oak wood by ion mobility spectrometer.

Talanta

Michalczuk B, Sabo M, Jatzová K, Moravský L, Gregorová M, Matejčík Š.
PMID: 31892077
Talanta. 2020 Mar 01;209:120567. doi: 10.1016/j.talanta.2019.120567. Epub 2019 Nov 16.

An Ion Mobility Spectrometry (IMS) apparatus has been used to detect the β-methyl-γ-octalactone (Whisky Lactone - WL) standard in the air and as well WL vapours originating from the oak wood samples. The IMS was equipped with Atmospheric Pressure...

Showing 1 to 12 of 23 entries