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Showing 1 to 12 of 36 entries
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The influence of glucocorticoid receptor single nucleotide polymorphisms on outcome after haematopoietic stem cell transplantation.

International journal of immunogenetics

Norden J, Pearce KF, Irving JAE, Collin MP, Wang XN, Wolff D, Kolb HJ, Socie G, Kuzmina Z, Greinix H, Holler E, Rocha V, Gluckman E, Hromadnikova I, Dickinson AM.
PMID: 30043490
Int J Immunogenet. 2018 Jul 25; doi: 10.1111/iji.12380. Epub 2018 Jul 25.

Haematopoietic stem cell transplantation (HSCT) remains the only cure for most haematological malignancies, however, the mortality rate remains high. Complications after HSCT include relapse, graft versus host disease (GvHD), graft rejection and infection. Over the last few years several...

Does Offline Beat Inline Treatment: Investigation into Extracorporeal Photopheresis.

Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie

Helmberg W, Sipurzynski S, Groselje-Strehle A, Greinix H, Schlenke P.
PMID: 32595424
Transfus Med Hemother. 2020 Jun;47(3):198-204. doi: 10.1159/000506750. Epub 2020 Mar 27.

BACKGROUND: Extracorporeal photopheresis is a therapy based on the induction of apoptosis to cells harvested from peripheral blood, followed by direct retransfusion. Currently, there are two approaches: inline procedures, where cell harvesting, 8-methoxypsoralen (8-MOP) incubation, and UV irradiation is...

Improved outcome of patients with graft-versus-host disease after allogeneic hematopoietic cell transplantation for hematologic malignancies over time: an EBMT mega-file study.

Haematologica

Greinix HT, Eikema DJ, Koster L, Penack O, Yakoub-Agha I, Montoto S, Chabannon C, Styczynski J, Nagler A, Robin M, Robinson S, Chalandon Y, Mikulska M, Schönland S, Peric Z, Ruggeri A, Lanza F, De Wreede LC, Mohty M, Basak GW, Kröger N.
PMID: 34162176
Haematologica. 2021 Jun 24; doi: 10.3324/haematol.2020.265769. Epub 2021 Jun 24.

Acute graft-versus-host disease (aGvHD) remains a major threat to successful outcome after allogeneic hematopoietic cell transplantation. Advances in prophylaxis and supportive care have taken place over the years. The aim of this study is to test whether incidence and...

Metabolomics: a novel way to diagnose cGVHD?.

Blood

Greinix HT.
PMID: 35024812
Blood. 2022 Jan 13;139(2):161-162. doi: 10.1182/blood.2021014041.

No abstract available.

Antibiotic use and ileocolonic immune cells in patients receiving fecal microbiota transplantation for refractory intestinal GvHD: a prospective cohort study.

Therapeutic advances in hematology

Spindelboeck W, Halwachs B, Bayer N, Huber-Krassnitzer B, Schulz E, Uhl B, Gaksch L, Hatzl S, Bachmayr V, Kleissl L, Kump P, Deutsch A, Stary G, Greinix H, Gorkiewicz G, Högenauer C, Neumeister P.
PMID: 34987741
Ther Adv Hematol. 2021 Dec 21;12:20406207211058333. doi: 10.1177/20406207211058333. eCollection 2021.

INTRODUCTION: Treatment-refractory, acute graft-METHODS: Consecutive patients with treatment-refractory GI-GvHD were treated with up to six endoscopically applied FMTs.RESULTS: We observed the response to FMT in four out of nine patients with severe, treatment refractory GI-GvHD, associated with a significant...

Immune Regulatory Processes of the Tumor Microenvironment under Malignant Conditions.

International journal of molecular sciences

Pansy K, Uhl B, Krstic J, Szmyra M, Fechter K, Santiso A, Thüminger L, Greinix H, Kargl J, Prochazka K, Feichtinger J, Deutsch AJ.
PMID: 34948104
Int J Mol Sci. 2021 Dec 10;22(24). doi: 10.3390/ijms222413311.

The tumor microenvironment (TME) is a critical regulator of tumor growth, progression, and metastasis. Since immune cells represent a large fraction of the TME, they play a key role in mediating pro- and anti-tumor immune responses. Immune escape, which...

Correction: Worldwide Network for Blood and Marrow Transplantation (WBMT) perspective: the role of biosimilars in hematopoietic cell transplant: current opportunities and challenges in low- and lower-middle income countries.

Bone marrow transplantation

Muhsen IN, Hashmi SK, Niederwieser D, Kroeger N, Agrawal S, Pasquini MC, Atsuta Y, Ballen KK, Seber A, Saber W, Kharfan-Dabaja MA, Rasheed W, Okamoto S, Khera N, Wood WA, Koh MBC, Greinix H, Kodera Y, Szer J, Horowitz MM, Weisdorf D, Aljurf M.
PMID: 31616063
Bone Marrow Transplant. 2020 Apr;55(4):837. doi: 10.1038/s41409-019-0714-y.

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

CD19+IgD+CD27- Naïve B Cells as Predictors of Humoral Response to COVID 19 mRNA Vaccination in Immunocompromised Patients.

Frontiers in immunology

Schulz E, Hodl I, Forstner P, Hatzl S, Sareban N, Moritz M, Fessler J, Dreo B, Uhl B, Url C, Grisold AJ, Khalil M, Kleinhappl B, Enzinger C, Stradner MH, Greinix HT, Schlenke P, Steinmetz I.
PMID: 34950155
Front Immunol. 2021 Dec 07;12:803742. doi: 10.3389/fimmu.2021.803742. eCollection 2021.

Immunocompromised patients are considered high-risk and prioritized for vaccination against COVID-19. We aimed to analyze B-cell subsets in these patients to identify potential predictors of humoral vaccination response. Patients (n=120) suffering from hematologic malignancies or other causes of immunodeficiency...

Therapeutic apheresis in hematopoietic cell transplantation.

Turkish journal of haematology : official journal of Turkish Society of Haematology

Worel N, Leitner G, Wagner A, Greinix HT, Höcker P, Kalhs P.
PMID: 27264917
Turk J Haematol. 2008 Dec 05;25(4):164-71.

With the introduction of hematopoietic stem cell transplant (HSCT), transplant-associated problems like graft-versus-host disease (GVHD) and transplant-associated microangiopathy (TAM) have occurred. In addition, approximately 40% of allogeneic HSCTs are performed across the ABO blood group barrier, bearing the risk...

Pre-transplantation Risks and Transplant-Techniques in Haematopoietic Stem Cell Transplantation for Acute Leukaemia.

EClinicalMedicine

Gratwohl A, Duarte R, Snowden JA, van Biezen A, Baldomero H, Apperley J, Cornelissen J, Greinix HT, Grath EM, Mohty M, Kroeger N, Nagler A, Niederwieser D, Putter H, Brand R.
PMID: 31709412
EClinicalMedicine. 2019 Aug 09;15:33-41. doi: 10.1016/j.eclinm.2019.07.019. eCollection 2019 Oct.

BACKGROUND: The role of conditioning intensity and stem cell source on modifying pre-transplantation risk in allogeneic haematopoietic stem cell transplantation (HSCT) is a matter of debate, but crucial when benchmarking centres.METHODS: This Retrospective, multicenter exploratory-validation analysis of 9103 patients,...

Author Correction: Humoral immune response to tick-borne encephalitis vaccination in allogeneic blood and marrow graft recipients.

NPJ vaccines

Harrison N, Grabmeier-Pfistershammer K, Graf A, Schwarzinger I, Aberle JH, Stiasny K, Greinix H, Rabitsch W, Kalhs P, Ramharter M, Burgmann H, Forstner C.
PMID: 34462440
NPJ Vaccines. 2020 Aug 31;5(1):79. doi: 10.1038/s41541-020-00230-2.

No abstract available.

Correction: Post-transplant multimorbidity index and quality of life in patients with chronic graft-versus-host disease-results from a joint evaluation of a prospective German multicenter validation trial and a cohort from the National Institutes of Health.

Bone marrow transplantation

Wolff D, Herzberg PY, Herrmann A, Pavletic SZ, Heussner P, Mumm F, Höfer C, Hilgendorf I, Hemmati PG, Holler E, Greinix H, Mitchell SA.
PMID: 34413472
Bone Marrow Transplant. 2021 Oct;56(10):2618. doi: 10.1038/s41409-021-01404-9.

No abstract available.

Showing 1 to 12 of 36 entries