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Showing 1 to 12 of 14 entries
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Differences in Signal Activation by LH and hCG are Mediated by the LH/CG Receptor's Extracellular Hinge Region.

Frontiers in endocrinology

Grzesik P, Kreuchwig A, Rutz C, Furkert J, Wiesner B, Schuelein R, Kleinau G, Gromoll J, Krause G.
PMID: 26441830
Front Endocrinol (Lausanne). 2015 Sep 22;6:140. doi: 10.3389/fendo.2015.00140. eCollection 2015.

The human lutropin (hLH)/choriogonadotropin (hCG) receptor (LHCGR) can be activated by binding two slightly different gonadotropic glycoprotein hormones, choriogonadotropin (CG) - secreted by the placenta, and lutropin (LH) - produced by the pituitary. They induce different signaling profiles at...

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Grzesik P, Kreuchwig A, Rutz C, et al. Differences in Signal Activation by LH and hCG are Mediated by the LH/CG Receptor's Extracellular Hinge Region. Front Endocrinol (Lausanne). 2015;6:140doi: 10.3389/fendo.2015.00140.
Grzesik, P., Kreuchwig, A., Rutz, C., Furkert, J., Wiesner, B., Schuelein, R., Kleinau, G., Gromoll, J., & Krause, G. (2015). Differences in Signal Activation by LH and hCG are Mediated by the LH/CG Receptor's Extracellular Hinge Region. Frontiers in endocrinology, 6140. https://doi.org/10.3389/fendo.2015.00140
Grzesik, Paul, et al. "Differences in Signal Activation by LH and hCG are Mediated by the LH/CG Receptor's Extracellular Hinge Region." Frontiers in endocrinology vol. 6 (2015): 140. doi: https://doi.org/10.3389/fendo.2015.00140
Grzesik P, Kreuchwig A, Rutz C, Furkert J, Wiesner B, Schuelein R, Kleinau G, Gromoll J, Krause G. Differences in Signal Activation by LH and hCG are Mediated by the LH/CG Receptor's Extracellular Hinge Region. Front Endocrinol (Lausanne). 2015 Sep 22;6:140. doi: 10.3389/fendo.2015.00140. eCollection 2015. PMID: 26441830; PMCID: PMC4585211.
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Pharmacogenetics of FSH Action in the Male.

Frontiers in endocrinology

Schubert M, Pérez Lanuza L, Gromoll J.
PMID: 30873114
Front Endocrinol (Lausanne). 2019 Feb 28;10:47. doi: 10.3389/fendo.2019.00047. eCollection 2019.

Male infertility is a major contributor to couple infertility, however in most cases it remains "idiopathic" and putative treatment regimens are lacking. This leads to a scenario in which intra-cytoplasmic spermatozoa injection (ICSI) is widely used in idiopathic male...

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Schubert M, Pérez Lanuza L, Gromoll J. Pharmacogenetics of FSH Action in the Male. Front Endocrinol (Lausanne). 2019;10:47doi: 10.3389/fendo.2019.00047.
Schubert, M., Pérez Lanuza, L., & Gromoll, J. (2019). Pharmacogenetics of FSH Action in the Male. Frontiers in endocrinology, 1047. https://doi.org/10.3389/fendo.2019.00047
Schubert, Maria, et al. "Pharmacogenetics of FSH Action in the Male." Frontiers in endocrinology vol. 10 (2019): 47. doi: https://doi.org/10.3389/fendo.2019.00047
Schubert M, Pérez Lanuza L, Gromoll J. Pharmacogenetics of FSH Action in the Male. Front Endocrinol (Lausanne). 2019 Feb 28;10:47. doi: 10.3389/fendo.2019.00047. eCollection 2019. PMID: 30873114; PMCID: PMC6403134.
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Does informal online media provide supportive or unreliable information about pregnancy and birth during the COVID-19 pandemic?.

Clinical medicine (London, England)

Pinto AC, Southall E, Gromala J, Graf V.
PMID: 34078688
Clin Med (Lond). 2021 Mar;21:32-33. doi: 10.7861/clinmed.21-2-s32.

No abstract available.

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Pinto AC, Southall E, Gromala J, et al. Does informal online media provide supportive or unreliable information about pregnancy and birth during the COVID-19 pandemic?. Clin Med (Lond). 2021;21:32-33doi: 10.7861/clinmed.21-2-s32.
Pinto, A. C., Southall, E., Gromala, J., & Graf, V. (2021). Does informal online media provide supportive or unreliable information about pregnancy and birth during the COVID-19 pandemic?. Clinical medicine (London, England), 2132-33. https://doi.org/10.7861/clinmed.21-2-s32
Pinto, Alexandra Cardoso, et al. "Does informal online media provide supportive or unreliable information about pregnancy and birth during the COVID-19 pandemic?." Clinical medicine (London, England) vol. 21 (2021): 32-33. doi: https://doi.org/10.7861/clinmed.21-2-s32
Pinto AC, Southall E, Gromala J, Graf V. Does informal online media provide supportive or unreliable information about pregnancy and birth during the COVID-19 pandemic?. Clin Med (Lond). 2021 Mar;21:32-33. doi: 10.7861/clinmed.21-2-s32. PMID: 34078688.
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FSHB Genotype Identified as a Relevant Diagnostic Parameter Revealed by Cluster Analysis of Men With Idiopathic Infertility.

Frontiers in endocrinology

Krenz H, Sansone A, Kliesch S, Gromoll J, Schubert M.
PMID: 34992580
Front Endocrinol (Lausanne). 2021 Dec 21;12:780403. doi: 10.3389/fendo.2021.780403. eCollection 2021.

INTRODUCTION AND OBJECTIVES: About 30-75% of infertile men are diagnosed with idiopathic infertility, thereby lacking major causative factors to explain their impaired fertility status. In this study, we used a large cohort of idiopathic infertile men to determine whether...

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Krenz H, Sansone A, Kliesch S, et al. FSHB Genotype Identified as a Relevant Diagnostic Parameter Revealed by Cluster Analysis of Men With Idiopathic Infertility. Front Endocrinol (Lausanne). 2021;12:780403doi: 10.3389/fendo.2021.780403.
Krenz, H., Sansone, A., Kliesch, S., Gromoll, J., & Schubert, M. (2021). FSHB Genotype Identified as a Relevant Diagnostic Parameter Revealed by Cluster Analysis of Men With Idiopathic Infertility. Frontiers in endocrinology, 12780403. https://doi.org/10.3389/fendo.2021.780403
Krenz, Henrike, et al. "FSHB Genotype Identified as a Relevant Diagnostic Parameter Revealed by Cluster Analysis of Men With Idiopathic Infertility." Frontiers in endocrinology vol. 12 (2021): 780403. doi: https://doi.org/10.3389/fendo.2021.780403
Krenz H, Sansone A, Kliesch S, Gromoll J, Schubert M. FSHB Genotype Identified as a Relevant Diagnostic Parameter Revealed by Cluster Analysis of Men With Idiopathic Infertility. Front Endocrinol (Lausanne). 2021 Dec 21;12:780403. doi: 10.3389/fendo.2021.780403. eCollection 2021. PMID: 34992580; PMCID: PMC8725293.
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Molecular Aging Markers in Patients with Klinefelter Syndrome.

Aging and disease

Pohl E, Muschal S, Kliesch S, Zitzmann M, Rohayem J, Gromoll J, Laurentino S.
PMID: 32489693
Aging Dis. 2020 May 09;11(3):470-476. doi: 10.14336/AD.2019.0801. eCollection 2020 May.

Molecular aging markers provide the opportunity for biological age determination in humans and to study factors, such as genetic determinants, affecting the ageing process. In males with Klinefelter syndrome (KS, non-mosaic karyotype 47, XXY), which is the most common...

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Pohl E, Muschal S, Kliesch S, et al. Molecular Aging Markers in Patients with Klinefelter Syndrome. Aging Dis. 2020;11(3):470-476doi: 10.14336/AD.2019.0801.
Pohl, E., Muschal, S., Kliesch, S., Zitzmann, M., Rohayem, J., Gromoll, J., & Laurentino, S. (2020). Molecular Aging Markers in Patients with Klinefelter Syndrome. Aging and disease, 11(3), 470-476. https://doi.org/10.14336/AD.2019.0801
Pohl, Eva, et al. "Molecular Aging Markers in Patients with Klinefelter Syndrome." Aging and disease vol. 11,3 (2020): 470-476. doi: https://doi.org/10.14336/AD.2019.0801
Pohl E, Muschal S, Kliesch S, Zitzmann M, Rohayem J, Gromoll J, Laurentino S. Molecular Aging Markers in Patients with Klinefelter Syndrome. Aging Dis. 2020 May 09;11(3):470-476. doi: 10.14336/AD.2019.0801. eCollection 2020 May. PMID: 32489693; PMCID: PMC7220296.
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FSHB Genotype Identified as a Relevant Diagnostic Parameter Revealed by Cluster Analysis of Men With Idiopathic Infertility.

Frontiers in endocrinology

Krenz H, Sansone A, Kliesch S, Gromoll J, Schubert M.
PMID: 34992580
Front Endocrinol (Lausanne). 2021 Dec 21;12:780403. doi: 10.3389/fendo.2021.780403. eCollection 2021.

INTRODUCTION AND OBJECTIVES: About 30-75% of infertile men are diagnosed with idiopathic infertility, thereby lacking major causative factors to explain their impaired fertility status. In this study, we used a large cohort of idiopathic infertile men to determine whether...

Cite
Krenz H, Sansone A, Kliesch S, et al. FSHB Genotype Identified as a Relevant Diagnostic Parameter Revealed by Cluster Analysis of Men With Idiopathic Infertility. Front Endocrinol (Lausanne). 2021;12:780403doi: 10.3389/fendo.2021.780403.
Krenz, H., Sansone, A., Kliesch, S., Gromoll, J., & Schubert, M. (2021). FSHB Genotype Identified as a Relevant Diagnostic Parameter Revealed by Cluster Analysis of Men With Idiopathic Infertility. Frontiers in endocrinology, 12780403. https://doi.org/10.3389/fendo.2021.780403
Krenz, Henrike, et al. "FSHB Genotype Identified as a Relevant Diagnostic Parameter Revealed by Cluster Analysis of Men With Idiopathic Infertility." Frontiers in endocrinology vol. 12 (2021): 780403. doi: https://doi.org/10.3389/fendo.2021.780403
Krenz H, Sansone A, Kliesch S, Gromoll J, Schubert M. FSHB Genotype Identified as a Relevant Diagnostic Parameter Revealed by Cluster Analysis of Men With Idiopathic Infertility. Front Endocrinol (Lausanne). 2021 Dec 21;12:780403. doi: 10.3389/fendo.2021.780403. eCollection 2021. PMID: 34992580; PMCID: PMC8725293.
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Healthy ageing and spermatogenesis.

Reproduction (Cambridge, England)

Pohl E, Gromoll J, Wistuba J, Laurentino S.
PMID: 33574214
Reproduction. 2021 Apr;161(4):R89-R101. doi: 10.1530/REP-20-0633.

Delayed family planning and increased parental age increase the risk for infertility and impaired offspring health. While the impact of ageing on oogenesis is well studied, this is less understood on spermatogenesis. Assessing ageing effects on the male germline...

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Pohl E, Gromoll J, Wistuba J, et al. Healthy ageing and spermatogenesis. Reproduction. 2021;161(4):R89-R101doi: 10.1530/REP-20-0633.
Pohl, E., Gromoll, J., Wistuba, J., & Laurentino, S. (2021). Healthy ageing and spermatogenesis. Reproduction (Cambridge, England), 161(4), R89-R101. https://doi.org/10.1530/REP-20-0633
Pohl, Eva, et al. "Healthy ageing and spermatogenesis." Reproduction (Cambridge, England) vol. 161,4 (2021): R89-R101. doi: https://doi.org/10.1530/REP-20-0633
Pohl E, Gromoll J, Wistuba J, Laurentino S. Healthy ageing and spermatogenesis. Reproduction. 2021 Apr;161(4):R89-R101. doi: 10.1530/REP-20-0633. PMID: 33574214.
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FSHB Genotype Identified as a Relevant Diagnostic Parameter Revealed by Cluster Analysis of Men With Idiopathic Infertility.

Frontiers in endocrinology

Krenz H, Sansone A, Kliesch S, Gromoll J, Schubert M.
PMID: 34992580
Front Endocrinol (Lausanne). 2021 Dec 21;12:780403. doi: 10.3389/fendo.2021.780403. eCollection 2021.

INTRODUCTION AND OBJECTIVES: About 30-75% of infertile men are diagnosed with idiopathic infertility, thereby lacking major causative factors to explain their impaired fertility status. In this study, we used a large cohort of idiopathic infertile men to determine whether...

Cite
Krenz H, Sansone A, Kliesch S, et al. FSHB Genotype Identified as a Relevant Diagnostic Parameter Revealed by Cluster Analysis of Men With Idiopathic Infertility. Front Endocrinol (Lausanne). 2021;12:780403doi: 10.3389/fendo.2021.780403.
Krenz, H., Sansone, A., Kliesch, S., Gromoll, J., & Schubert, M. (2021). FSHB Genotype Identified as a Relevant Diagnostic Parameter Revealed by Cluster Analysis of Men With Idiopathic Infertility. Frontiers in endocrinology, 12780403. https://doi.org/10.3389/fendo.2021.780403
Krenz, Henrike, et al. "FSHB Genotype Identified as a Relevant Diagnostic Parameter Revealed by Cluster Analysis of Men With Idiopathic Infertility." Frontiers in endocrinology vol. 12 (2021): 780403. doi: https://doi.org/10.3389/fendo.2021.780403
Krenz H, Sansone A, Kliesch S, Gromoll J, Schubert M. FSHB Genotype Identified as a Relevant Diagnostic Parameter Revealed by Cluster Analysis of Men With Idiopathic Infertility. Front Endocrinol (Lausanne). 2021 Dec 21;12:780403. doi: 10.3389/fendo.2021.780403. eCollection 2021. PMID: 34992580; PMCID: PMC8725293.
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[No title available]

mHealth

McCoy SI, Buzdugan R, Grimball R, Natoli L, Mejia CM, Klausner JD, McGrath MR.
PMID: 30363751
Mhealth. 2018 Sep 25;4:40. doi: 10.21037/mhealth.2018.09.04. eCollection 2018.

BACKGROUND: In the United States, young men who have sex with men (YMSM) experience a disproportionate burden of HIV and sexually transmitted infections (STIs). Mobile health (mHealth) interventions, including those that incorporate elements of games ("gamification"), have the potential...

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McCoy SI, Buzdugan R, Grimball R, et al. . Mhealth. 2018;4:40doi: 10.21037/mhealth.2018.09.04.
McCoy, S. I., Buzdugan, R., Grimball, R., Natoli, L., Mejia, C. M., Klausner, J. D., & McGrath, M. R. (2018). . mHealth, 440. https://doi.org/10.21037/mhealth.2018.09.04
McCoy, Sandra I, et al. "." mHealth vol. 4 (2018): 40. doi: https://doi.org/10.21037/mhealth.2018.09.04
McCoy SI, Buzdugan R, Grimball R, Natoli L, Mejia CM, Klausner JD, McGrath MR. . Mhealth. 2018 Sep 25;4:40. doi: 10.21037/mhealth.2018.09.04. eCollection 2018. PMID: 30363751; PMCID: PMC6182020.
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Machine learning based prediction models in male reproductive health: development of a proof-of-concept model for Klinefelter Syndrome in azoospermic patients.

Andrology

Krenz H, Sansone A, Fujarski M, Krallmann C, Zitzmann M, Dugas M, Kliesch S, Varghese J, Tüttelmann F, Gromoll J.
PMID: 34914193
Andrology. 2021 Dec 16; doi: 10.1111/andr.13141. Epub 2021 Dec 16.

BACKGROUND: Due to the highly variable clinical phenotype, Klinefelter Syndrome (KS) is underdiagnosed.OBJECTIVE: Assessment of supervised machine learning (sML)-based prediction models for identification of KS among azoospermic patients, and comparison to expert clinical evaluation.MATERIALS AND METHODS: Retrospective patient data...

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Krenz H, Sansone A, Fujarski M, et al. Machine learning based prediction models in male reproductive health: development of a proof-of-concept model for Klinefelter Syndrome in azoospermic patients. Andrology. 2021;doi: 10.1111/andr.13141.
Krenz, H., Sansone, A., Fujarski, M., Krallmann, C., Zitzmann, M., Dugas, M., Kliesch, S., Varghese, J., Tüttelmann, F., & Gromoll, J. (2021). Machine learning based prediction models in male reproductive health: development of a proof-of-concept model for Klinefelter Syndrome in azoospermic patients. Andrology, . https://doi.org/10.1111/andr.13141
Krenz, H, et al. "Machine learning based prediction models in male reproductive health: development of a proof-of-concept model for Klinefelter Syndrome in azoospermic patients." Andrology vol. (2021). doi: https://doi.org/10.1111/andr.13141
Krenz H, Sansone A, Fujarski M, Krallmann C, Zitzmann M, Dugas M, Kliesch S, Varghese J, Tüttelmann F, Gromoll J. Machine learning based prediction models in male reproductive health: development of a proof-of-concept model for Klinefelter Syndrome in azoospermic patients. Andrology. 2021 Dec 16; doi: 10.1111/andr.13141. Epub 2021 Dec 16. PMID: 34914193.
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Further heterogeneity in Silver-Russell syndrome: PLAG1 deletion in association with a complex chromosomal rearrangement.

American journal of medical genetics. Part A

Brereton RE, Nickerson SL, Woodward KJ, Edwards T, Sivamoorthy S, Ramos Vasques Walters F, Chabros V, Marchin V, Grumball T, Kennedy D, Uzaraga J, Peverall J, Arscott G, Beilby J, Choong CS, Townshend S, Azmanov DN.
PMID: 34223693
Am J Med Genet A. 2021 Oct;185(10):3136-3145. doi: 10.1002/ajmg.a.62391. Epub 2021 Jul 05.

Silver-Russell syndrome (SRS) is a rare genetic condition primarily characterized by growth restriction and facial dysmorphisms. While hypomethylation of H19/IGF2:IG-DMR (imprinting control region 1 [IC1]) located at 11p15.5 and maternal uniparental disomy of chromosome 7 (upd[7]mat) are the most...

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Brereton RE, Nickerson SL, Woodward KJ, et al. Further heterogeneity in Silver-Russell syndrome: PLAG1 deletion in association with a complex chromosomal rearrangement. Am J Med Genet A. 2021;185(10):3136-3145doi: 10.1002/ajmg.a.62391.
Brereton, R. E., Nickerson, S. L., Woodward, K. J., Edwards, T., Sivamoorthy, S., Ramos Vasques Walters, F., Chabros, V., Marchin, V., Grumball, T., Kennedy, D., Uzaraga, J., Peverall, J., Arscott, G., Beilby, J., Choong, C. S., Townshend, S., & Azmanov, D. N. (2021). Further heterogeneity in Silver-Russell syndrome: PLAG1 deletion in association with a complex chromosomal rearrangement. American journal of medical genetics. Part A, 185(10), 3136-3145. https://doi.org/10.1002/ajmg.a.62391
Brereton, Rebecca E, et al. "Further heterogeneity in Silver-Russell syndrome: PLAG1 deletion in association with a complex chromosomal rearrangement." American journal of medical genetics. Part A vol. 185,10 (2021): 3136-3145. doi: https://doi.org/10.1002/ajmg.a.62391
Brereton RE, Nickerson SL, Woodward KJ, Edwards T, Sivamoorthy S, Ramos Vasques Walters F, Chabros V, Marchin V, Grumball T, Kennedy D, Uzaraga J, Peverall J, Arscott G, Beilby J, Choong CS, Townshend S, Azmanov DN. Further heterogeneity in Silver-Russell syndrome: PLAG1 deletion in association with a complex chromosomal rearrangement. Am J Med Genet A. 2021 Oct;185(10):3136-3145. doi: 10.1002/ajmg.a.62391. Epub 2021 Jul 05. PMID: 34223693.
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Bilateral atraumatic medial meniscal tears in a 17-year-old rower.

BMJ case reports

Taylor TL, Frankovich R, Rumball J.
PMID: 21686387
BMJ Case Rep. 2009;2009. doi: 10.1136/bcr.11.2008.1258. Epub 2009 May 17.

Meniscal injury produces disability in a large portion of the population, and sports injuries are a common cause. Atraumatic meniscal tears may occur after repetitive low-energy loading. Rowing is a highly technical sport and very demanding on an athlete's...

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Taylor TL, Frankovich R, Rumball J. Bilateral atraumatic medial meniscal tears in a 17-year-old rower. BMJ Case Rep. 2009;2009doi: 10.1136/bcr.11.2008.1258.
Taylor, T. L., Frankovich, R., & Rumball, J. (2009). Bilateral atraumatic medial meniscal tears in a 17-year-old rower. BMJ case reports, 2009. https://doi.org/10.1136/bcr.11.2008.1258
Taylor, Taryn Lise, et al. "Bilateral atraumatic medial meniscal tears in a 17-year-old rower." BMJ case reports vol. 2009 (2009). doi: https://doi.org/10.1136/bcr.11.2008.1258
Taylor TL, Frankovich R, Rumball J. Bilateral atraumatic medial meniscal tears in a 17-year-old rower. BMJ Case Rep. 2009;2009. doi: 10.1136/bcr.11.2008.1258. Epub 2009 May 17. PMID: 21686387; PMCID: PMC3028201.
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Showing 1 to 12 of 14 entries