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Showing 1 to 12 of 30 entries
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Cocaine enhances HIV-1 gp120-induced lymphatic endothelial dysfunction in the lung.

Physiological reports

Zhang X, Jiang S, Yu J, Kuzontkoski PM, Groopman JE.
PMID: 26311830
Physiol Rep. 2015 Aug;3(8). doi: 10.14814/phy2.12482.

Pulmonary complications are common in both AIDS patients and cocaine users. We addressed the cellular and molecular mechanisms by which HIV and cocaine may partner to induce their deleterious effects. Using primary lung lymphatic endothelial cells (L-LECs), we examined...

Early Life Metabolism of Bisphenol A: A Systematic Review of the Literature.

Current environmental health reports

Nachman RM, Hartle JC, Lees PS, Groopman JD.
PMID: 25838989
Curr Environ Health Rep. 2014 Mar;1(1):90-100. doi: 10.1007/s40572-013-0003-7.

When a comprehensive report on BPA was published in 2008, few data were available to assess the extent to which known poor glucuronidation capacity impacts BPA internal dose in infants and young children. In this paper, evidence that has...

Qidong hepatitis B virus infection cohort: a 25-year prospective study in high risk area of primary liver cancer.

Hepatoma research

Chen T, Qian G, Fan C, Sun Y, Wang J, Lu P, Xue X, Wu Y, Zhang Q, Jin Y, Wu Y, Gan Y, Lu J, Kensler TW, Groopman JD, Tu H.
PMID: 29479565
Hepatoma Res. 2018;4. doi: 10.20517/2394-5079.2017.50. Epub 2018 Jan 26.

Qidong hepatitis B virus (HBV) infection cohort (QBC) is a prospective community-based study designed to investigate causative factors of primary liver cancer (PLC) in Qidong, China, where both PLC and HBV infection are highly endemic. Residents aged 20-65 years,...

Unusual Case of Lipoprotein Glomerulopathy First Diagnosed in a Protocol Kidney Allograft Biopsy.

Kidney international reports

Batal I, Fakhoury G, Groopman E, D'Agati VD, Morris H.
PMID: 30775634
Kidney Int Rep. 2018 Sep 28;4(2):350-354. doi: 10.1016/j.ekir.2018.09.020. eCollection 2019 Feb.

No abstract available.

Environmental Pollutants, Mucosal Barriers, and Pathogen Susceptibility; The Case for Aflatoxin B.

Pathogens (Basel, Switzerland)

Madeen EP, Maldarelli F, Groopman JD.
PMID: 34684180
Pathogens. 2021 Sep 23;10(10). doi: 10.3390/pathogens10101229.

HIV transmission risk is dependent on the infectivity of the HIV+ partner and personal susceptibility risk factors of the HIV- partner. The mucosal barrier, as the internal gatekeeper between environment and self, concentrates and modulates the internalization of ingested...

Analysis of .

Health science reports

Alvarez CS, Ortiz J, Bendfeldt-Avila G, Xie Y, Wang M, Wu D, Higson H, Lee E, Teshome K, Barnoya J, Kleiner DE, Groopman JD, Orozco R, McGlynn KA, Gharzouzi E, Dean M.
PMID: 32382660
Health Sci Rep. 2020 May 06;3(2):e155. doi: 10.1002/hsr2.155. eCollection 2020 Jun.

BACKGROUND AND AIMS: Guatemala has the highest incidence of hepatocellular carcinoma (HCC) in the Western hemisphere. The major risk factors in Guatemala are not well characterized, but the prevalence of hepatitis B virus (HBV) and hepatitis C virus (HCV)...

Cyclohexanone Exposure in Children on Extracorporeal Membrane Oxygenation Support.

ASAIO journal (American Society for Artificial Internal Organs : 1992)

Bembea MM, Ng DK, Carroll M, Roem JL, Groopman J, Caprarola SD, McElrath Schwartz J, Felling RJ, Salorio CF, Ellis G, Graham D, Everett AD.
PMID: 33989209
ASAIO J. 2021 May 12; doi: 10.1097/MAT.0000000000001463. Epub 2021 May 12.

The aim of this study was to determine if plasma cyclohexanone and metabolites are associated with clinical outcomes of children on extracorporeal membrane oxygenation (ECMO) support. We performed a secondary analysis of a prospective observational study of children on...

Decreased oxidative DNA damage and accelerated cell turnover in woodchuck hepatitis virus infected liver.

Hepatology research : the official journal of the Japan Society of Hepatology

O'Gorman MA, Sharma S, Groopman JD, Tennant BC, Tochkov IA, Schwarz KB.
PMID: 12697246
Hepatol Res. 2003 Mar;25(3):254-262. doi: 10.1016/s1386-6346(02)00266-8.

Infection of newborn woodchucks with woodchuck hepatitis virus (WHV) results in hepatocellular carcinoma (HCC). Since oxidative damage may be carcinogenic, we investigated the relationship between WHV infection and oxidative damage to hepatic lipids and DNA. Eastern woodchucks were infected...

Qidong: a crucible for studies on liver cancer etiology and prevention.

Cancer biology & medicine

Chen J, Zhu J, Wang G, Groopman JD, Kensler TW.
PMID: 31119044
Cancer Biol Med. 2019 Feb;16(1):24-37. doi: 10.20892/j.issn.2095-3941.2018.0394.

Qidong (Jiangsu, China) has been of interest to cancer epidemiologists and biologists because, until recently, it was an endemic area for liver cancer, having amongst the highest incidence rates in the world. The establishment of the Qidong Cancer Registry...

Jamming in systems with quenched disorder.

Physical review. E, Statistical, nonlinear, and soft matter physics

Olson Reichhardt CJ, Groopman E, Nussinov Z, Reichhardt C.
PMID: 23367926
Phys Rev E Stat Nonlin Soft Matter Phys. 2012 Dec;86(6):061301. doi: 10.1103/PhysRevE.86.061301. Epub 2012 Dec 03.

We numerically study the effect of adding quenched disorder in the form of randomly placed pinning sites on jamming transitions in a disk packing that jams at a well-defined point J in the clean limit. Quenched disorder decreases the...

Scratching the surface.

Current biology : CB

Scadden DT, Feder D, Groopman JE.
PMID: 15336104
Curr Biol. 1991 Oct;1(5):301-3. doi: 10.1016/0960-9822(91)90091-a.

No abstract available.

Evolution of root plasticity responses to variation in soil nutrient distribution and concentration.

Evolutionary applications

Grossman JD, Rice KJ.
PMID: 23346229
Evol Appl. 2012 Dec;5(8):850-7. doi: 10.1111/j.1752-4571.2012.00263.x.

Root plasticity, a trait that can respond to selective pressure, may help plants forage for nutrients in heterogeneous soils. Agricultural breeding programs have artificially selected for increased yield under comparatively homogeneous soil conditions, potentially decreasing the capacity for plasticity...

Showing 1 to 12 of 30 entries