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Incidence and mortality of lung cancer: global trends and association with socioeconomic status.

Scientific reports

Wong MCS, Lao XQ, Ho KF, Goggins WB, Tse SLA.
PMID: 29085026
Sci Rep. 2017 Oct 30;7(1):14300. doi: 10.1038/s41598-017-14513-7.

We examined the correlation between lung cancer incidence/mortality and country-specific socioeconomic development, and evaluated its most recent global trends. We retrieved its age-standardized incidence rates from the GLOBOCAN database, and temporal patterns were assessed from global databases. We employed...

Effects of 17-allylamino-17-demethoxygeldanamycin (17-AAG) in transgenic mouse models of frontotemporal lobar degeneration and Alzheimer's disease.

Translational neurodegeneration

Ho SW, Tsui YT, Wong TT, Cheung SK, Goggins WB, Yi LM, Cheng KK, Baum L.
PMID: 24344631
Transl Neurodegener. 2013 Dec 17;2(1):24. doi: 10.1186/2047-9158-2-24.

Alzheimer's disease (AD), the most common dementia, is characterized by potentially neurotoxic aggregation of Aβ peptide and tau protein, and their deposition as amyloid plaques and neurofibrillary tangles (NFTs). Tau aggregation also occurs in other common neurodegenerative diseases. Frontotemporal...

Functional Signatures of Human CD4 and CD8 T Cell Responses to Mycobacterium tuberculosis.

Frontiers in immunology

Prezzemolo T, Guggino G, La Manna MP, Di Liberto D, Dieli F, Caccamo N.
PMID: 24795723
Front Immunol. 2014 Apr 22;5:180. doi: 10.3389/fimmu.2014.00180. eCollection 2014.

With 1.4 million deaths and 8.7 million new cases in 2011, tuberculosis (TB) remains a global health care problem and together with HIV and Malaria represents one of the three infectious diseases world-wide. Control of the global TB epidemic...

Complement yourself: Transcomplementation rescues partially folded mutant proteins.

Biophysical reviews

Cebotaru L, Guggino WB.
PMID: 24949105
Biophys Rev. 2014 Mar 01;6(1):169-180. doi: 10.1007/s12551-014-0137-3.

Cystic Fibrosis (CF) is an autosomal disease associated with malfunction in fluid and electrolyte transport across several mucosal membranes. The most common mutation in CF is an in-frame three-base pair deletion that removes a phenylalanine at position 508 in...

The effects of blue and far red light on rhythmic leaflet movements in samanea and albizzia.

Plant physiology

Satter RL, Guggino SE, Lonergan TA, Galston AW.
PMID: 16661802
Plant Physiol. 1981 May;67(5):965-8. doi: 10.1104/pp.67.5.965.

The opening of excised Samanea saman pulvini is promoted by prolonged blue or far-red irradiation. Far-red effects are attributed partially but not completely to lowering of the Pfr level. Two hours of continuous or pulsed blue light or pulsed...

The Mitochondrial Ca.

Cell calcium

Yanda MK, Tomar V, Cole R, Guggino WB, Cebotaru L.
PMID: 34823104
Cell Calcium. 2021 Nov 19;101:102501. doi: 10.1016/j.ceca.2021.102501. Epub 2021 Nov 19.

Mutations in either of the polycystic kidney disease genes, PKD1 or PKD2, engender the growth of cysts, altering renal function. Cystic growth is supported by major changes in cellular metabolism, some of which involve the mitochondrion, a major storage...

Association of weather, air pollutants, and seasonal influenza with chronic obstructive pulmonary disease hospitalization risks.

Environmental pollution (Barking, Essex : 1987)

Chong KC, Chen Y, Chan EYY, Lau SYF, Lam HCY, Wang P, Goggins WB, Ran J, Zhao S, Mohammad KN, Wei Y.
PMID: 34763018
Environ Pollut. 2022 Jan 15;293:118480. doi: 10.1016/j.envpol.2021.118480. Epub 2021 Nov 09.

The influences of weather and air pollutants on chronic obstructive pulmonary disease (COPD) have been well-studied. However, the heterogeneous effects of different influenza viral infections, air pollution and weather on COPD admissions and re-admissions have not been thoroughly examined....

A giant mediastinal teratoma: From diagnosis to complete resection and restitutio ad integrum.

Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace

Cocchia R, Guggino G, Romano L, Annunziata R, Raucci A, Sorice M, Ranieri B, Russo G, Mauro C, Bossone E.
PMID: 34585559
Monaldi Arch Chest Dis. 2021 Sep 28; doi: 10.4081/monaldi.2021.1935. Epub 2021 Sep 28.

The current report highlights the integrated work-up of an unexpected giant mediastinal teratoma in 28 years old female. A comprehensive multi-modality imaging approach was implemented in order to define the diagnosis and tailor the most appropriate surgical intervention.

Protein microarray platforms for clinical proteomics.

Proteomics. Clinical applications

Pollard HB, Srivastava M, Eidelman O, Jozwik C, Rothwell SW, Mueller GP, Jacobowitz DM, Darling T, Guggino WB, Wright J, Zeitlin PL, Paweletz CP.
PMID: 21136748
Proteomics Clin Appl. 2007 Sep;1(9):934-52. doi: 10.1002/prca.200700154. Epub 2007 Aug 10.

Proteomics for clinical applications is presently in a state of transition. It has become clear that the classical approaches based on 2-DE and/or MS need to be complemented by different kinds of technologies. The well-known problems include sample complexity,...

The Mitochondrial Ca.

Cell calcium

Yanda MK, Tomar V, Cole R, Guggino WB, Cebotaru L.
PMID: 34823104
Cell Calcium. 2021 Nov 19;101:102501. doi: 10.1016/j.ceca.2021.102501. Epub 2021 Nov 19.

Mutations in either of the polycystic kidney disease genes, PKD1 or PKD2, engender the growth of cysts, altering renal function. Cystic growth is supported by major changes in cellular metabolism, some of which involve the mitochondrion, a major storage...

Secukinumab efficacy in patients with PsA is not dependent on patients' body mass index.

Annals of the rheumatic diseases

Pantano I, Iacono D, Favalli EG, Scalise G, Costa L, Caso F, Guggino G, Scarpa R, Ciccia F.
PMID: 32169970
Ann Rheum Dis. 2020 Mar 13; doi: 10.1136/annrheumdis-2020-217251. Epub 2020 Mar 13.

No abstract available.

Primary Sjogren Syndrome: Focus on Innate Immune Cells and Inflammation.

Vaccines

Rizzo C, Grasso G, Destro Castaniti GM, Ciccia F, Guggino G.
PMID: 32503132
Vaccines (Basel). 2020 Jun 03;8(2). doi: 10.3390/vaccines8020272.

Primary Sjogren Syndrome (pSS) is a complex, multifactorial rheumatic disease that mainly targets salivary and lacrimal glands, inducing epithelitis. The cause behind the autoimmunity outbreak in pSS is still elusive; however, it seems related to an aberrant reaction to...

Showing 1 to 12 of 50 entries