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Showing 1 to 12 of 17 entries
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Genetic Characterization of Ten-Eleven-Translocation Methylcytosine Dioxygenase Alterations in Human Glioma.

Journal of Cancer

Kraus TF, Greiner A, Steinmaurer M, Dietinger V, Guibourt V, Kretzschmar HA.
PMID: 26284134
J Cancer. 2015 Jul 15;6(9):832-42. doi: 10.7150/jca.12010. eCollection 2015.

The molecular mechanisms leading to brain tumors still remain unclear. Nevertheless, there is increasing evidence that epigenetic effects play crucial roles in tumor development and progression. Thereby, 5-hydroxymethylcytosine (5hmC) represents a further base modification of cytosine besides 5-methylcytosine (5mC)....

Precision medicine for patients with gastro-oesophageal cancer: A subset analysis of the ProfiLER program.

Translational oncology

Cassier PA, Peyramaure C, Attignon V, Eberst L, Pacaud C, Boyault S, Desseigne F, Sarabi M, Guibert P, Rochefort P, Marques N, Rivoire M, Dupré A, Peyrat P, Terret C, Ray-Coquard I, Coutzac C, Pérol D, Blay JY, Trédan O, de la Fouchardière C.
PMID: 34794033
Transl Oncol. 2022 Jan;15(1):101266. doi: 10.1016/j.tranon.2021.101266. Epub 2021 Nov 15.

BACKGROUND: Chemotherapy, anti-HER2 and PD-1 antibodies are standard treatments but only a minority of patients derive long-term benefit from these agents.METHODS: In this report we describe the mutational landscape and outcome of patients with gastroesophageal cancers enroled in the...

Hyperprogressive Disease After Combined Anti-PD-L1 and Anti-CTLA-4 Immunotherapy for MSI-H/dMMR Gastric Cancer: A Case Report.

Frontiers in oncology

Varnier R, Garrivier T, Hafliger E, Favre A, Coutzac C, Spire C, Rochefort P, Sarabi M, Desseigne F, Guibert P, Cattey-Javouhey A, Funk-Debleds P, Mastier C, Buisson A, Pérol D, Trédan O, Blay JY, Phelip JM, de la Fouchardiere C.
PMID: 34631593
Front Oncol. 2021 Sep 24;11:756365. doi: 10.3389/fonc.2021.756365. eCollection 2021.

Immune checkpoint inhibitors (ICI) have been developed in gastric adenocarcinomas and approved in first-line metastatic setting (in combination with chemotherapy) as well as in pretreated patients. Microsatellite instability-high (MSI-H) tumors are predicted to derive high benefit from ICI but...

Precision medicine for patients with gastro-oesophageal cancer: A subset analysis of the ProfiLER program.

Translational oncology

Cassier PA, Peyramaure C, Attignon V, Eberst L, Pacaud C, Boyault S, Desseigne F, Sarabi M, Guibert P, Rochefort P, Marques N, Rivoire M, Dupré A, Peyrat P, Terret C, Ray-Coquard I, Coutzac C, Pérol D, Blay JY, Trédan O, de la Fouchardière C.
PMID: 34794033
Transl Oncol. 2021 Nov 15;15(1):101266. doi: 10.1016/j.tranon.2021.101266. Epub 2021 Nov 15.

BACKGROUND: Chemotherapy, anti-HER2 and PD-1 antibodies are standard treatments but only a minority of patients derive long-term benefit from these agents.METHODS: In this report we describe the mutational landscape and outcome of patients with gastroesophageal cancers enroled in the...

20-Hydroxyecdysone activates the protective arm of the RAAS via the MAS receptor.

Journal of molecular endocrinology

Lafont R, Serova M, Didry-Barca B, Raynal S, Guibout L, Dinan L, Veillet S, Latil M, Dioh W, Dilda PJ.
PMID: 34825653
J Mol Endocrinol. 2021 Dec 23;68(2):77-87. doi: 10.1530/JME-21-0033.

20-Hydroxyecdysone (20E) is a steroid hormone that plays a key role in insect development through nuclear ecdysteroid receptors (EcR/RXR complex) and at least one membrane GPCR receptor (DopEcR). It also displays numerous pharmacological effects in mammals, where its mechanism...

Oral Condition and Incident Coronary Heart Disease: A Clustering Analysis.

Journal of dental research

Deraz O, Rangé H, Boutouyrie P, Chatzopoulou E, Asselin A, Guibout C, Van Sloten T, Bougouin W, Andrieu M, Vedié B, Thomas F, Danchin N, Jouven X, Bouchard P, Empana JP.
PMID: 34875909
J Dent Res. 2021 Dec 07;220345211052507. doi: 10.1177/00220345211052507. Epub 2021 Dec 07.

Poor oral health has been linked to coronary heart disease (CHD). Clustering clinical oral conditions routinely recorded in adults may identify their CHD risk profile. Participants from the Paris Prospective Study 3 received, between 2008 and 2012, a baseline...

Precision medicine for patients with gastro-oesophageal cancer: A subset analysis of the ProfiLER program.

Translational oncology

Cassier PA, Peyramaure C, Attignon V, Eberst L, Pacaud C, Boyault S, Desseigne F, Sarabi M, Guibert P, Rochefort P, Marques N, Rivoire M, Dupré A, Peyrat P, Terret C, Ray-Coquard I, Coutzac C, Pérol D, Blay JY, Trédan O, de la Fouchardière C.
PMID: 34794033
Transl Oncol. 2021 Nov 15;15(1):101266. doi: 10.1016/j.tranon.2021.101266. Epub 2021 Nov 15.

BACKGROUND: Chemotherapy, anti-HER2 and PD-1 antibodies are standard treatments but only a minority of patients derive long-term benefit from these agents.METHODS: In this report we describe the mutational landscape and outcome of patients with gastroesophageal cancers enroled in the...

Precision medicine for patients with gastro-oesophageal cancer: A subset analysis of the ProfiLER program.

Translational oncology

Cassier PA, Peyramaure C, Attignon V, Eberst L, Pacaud C, Boyault S, Desseigne F, Sarabi M, Guibert P, Rochefort P, Marques N, Rivoire M, Dupré A, Peyrat P, Terret C, Ray-Coquard I, Coutzac C, Pérol D, Blay JY, Trédan O, de la Fouchardière C.
PMID: 34794033
Transl Oncol. 2021 Nov 15;15(1):101266. doi: 10.1016/j.tranon.2021.101266. Epub 2021 Nov 15.

BACKGROUND: Chemotherapy, anti-HER2 and PD-1 antibodies are standard treatments but only a minority of patients derive long-term benefit from these agents.METHODS: In this report we describe the mutational landscape and outcome of patients with gastroesophageal cancers enroled in the...

Corrigendum to: Validation of a pneumatic tube system to transport surgical pathology biopsy samples.

Clinical chemistry and laboratory medicine

Guibourg B, Marcorelles P, Uguen A.
PMID: 29288617
Clin Chem Lab Med. 2018 Mar 28;56(4):681. doi: 10.1515/cclm-2017-1012.

No abstract available.

Use of gemcitabine as a second-line treatment following chemotherapy with folfirinox for metastatic pancreatic adenocarcinoma.

Oncology letters

Sarabi M, Mais L, Oussaid N, Desseigne F, Guibert P, De La Fouchardiere C.
PMID: 28599496
Oncol Lett. 2017 Jun;13(6):4917-4924. doi: 10.3892/ol.2017.6061. Epub 2017 Apr 20.

There is a lack of prospective data about second-line treatments for metastatic pancreatic ductal adenocarcinoma patients. This is partially due to recent changes in first-line chemotherapy treatments. Despite this dearth of information, 50.0% of the patients who experience failure...

Identification of Stably Expressed lncRNAs as Valid Endogenous Controls for Profiling of Human Glioma.

Journal of Cancer

Kraus TF, Greiner A, Guibourt V, Lisec K, Kretzschmar HA.
PMID: 25561975
J Cancer. 2015 Jan 01;6(2):111-9. doi: 10.7150/jca.10867. eCollection 2015.

BACKGROUND: Recent research indicates that long non-coding RNAs (lncRNA) represent a new family of RNAs that is of fundamental importance for controlling transcription and translation. Thereby, there is increasing evidence that lncRNAs are also important in tumourigenesis. Thereby valid...

A2E-induced inflammation and angiogenesis in RPE cells .

Aging

Fontaine V, Fournié M, Monteiro E, Boumedine T, Balducci C, Guibout L, Latil M, Sahel JA, Veillet S, Dilda PJ, Lafont R, Camelo S.
PMID: 34544906
Aging (Albany NY). 2021 Sep 20;13(18):22040-22058. doi: 10.18632/aging.203558. Epub 2021 Sep 20.

No abstract available.

Showing 1 to 12 of 17 entries