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A Guideline to Univariate Statistical Analysis for LC/MS-Based Untargeted Metabolomics-Derived Data.

Metabolites

Vinaixa M, Samino S, Saez I, Duran J, Guinovart JJ, Yanes O.
PMID: 24957762
Metabolites. 2012 Oct 18;2(4):775-95. doi: 10.3390/metabo2040775.

Several metabolomic software programs provide methods for peak picking, retention time alignment and quantification of metabolite features in LC/MS-based metabolomics. Statistical analysis, however, is needed in order to discover those features significantly altered between samples. By comparing the retention...

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Vinaixa M, Samino S, Saez I, et al. A Guideline to Univariate Statistical Analysis for LC/MS-Based Untargeted Metabolomics-Derived Data. Metabolites. 2012;2(4):775-95doi: 10.3390/metabo2040775.
Vinaixa, M., Samino, S., Saez, I., Duran, J., Guinovart, J. J., & Yanes, O. (2012). A Guideline to Univariate Statistical Analysis for LC/MS-Based Untargeted Metabolomics-Derived Data. Metabolites, 2(4), 775-95. https://doi.org/10.3390/metabo2040775
Vinaixa, Maria, et al. "A Guideline to Univariate Statistical Analysis for LC/MS-Based Untargeted Metabolomics-Derived Data." Metabolites vol. 2,4 (2012): 775-95. doi: https://doi.org/10.3390/metabo2040775
Vinaixa M, Samino S, Saez I, Duran J, Guinovart JJ, Yanes O. A Guideline to Univariate Statistical Analysis for LC/MS-Based Untargeted Metabolomics-Derived Data. Metabolites. 2012 Oct 18;2(4):775-95. doi: 10.3390/metabo2040775. PMID: 24957762; PMCID: PMC3901240.
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A novel miniaturized radiofrequency potentiometer tag using ion-selective electrodes for wireless ion sensing.

The Analyst

Novell M, Guinovart T, Steinberg IM, Steinberg M, Rius FX, Andrade FJ.
PMID: 23857560
Analyst. 2013 Sep 21;138(18):5250-7. doi: 10.1039/c3an00727h. Epub 2013 Jul 16.

Instrumental approaches to remotely and wirelessly monitoring chemical species are increasingly needed. Together with the electronic developments, efforts to optimize and validate the performance of these new devices are required. In this work, the analytical performance of a recently...

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Novell M, Guinovart T, Steinberg IM, et al. A novel miniaturized radiofrequency potentiometer tag using ion-selective electrodes for wireless ion sensing. Analyst. 2013;138(18):5250-7doi: 10.1039/c3an00727h.
Novell, M., Guinovart, T., Steinberg, I. M., Steinberg, M., Rius, F. X., & Andrade, F. J. (2013). A novel miniaturized radiofrequency potentiometer tag using ion-selective electrodes for wireless ion sensing. The Analyst, 138(18), 5250-7. https://doi.org/10.1039/c3an00727h
Novell, Marta, et al. "A novel miniaturized radiofrequency potentiometer tag using ion-selective electrodes for wireless ion sensing." The Analyst vol. 138,18 (2013): 5250-7. doi: https://doi.org/10.1039/c3an00727h
Novell M, Guinovart T, Steinberg IM, Steinberg M, Rius FX, Andrade FJ. A novel miniaturized radiofrequency potentiometer tag using ion-selective electrodes for wireless ion sensing. Analyst. 2013 Sep 21;138(18):5250-7. doi: 10.1039/c3an00727h. Epub 2013 Jul 16. PMID: 23857560.
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Spectral counting assessment of protein dynamic range in cerebrospinal fluid following depletion with plasma-designed immunoaffinity columns.

Clinical proteomics

Borg J, Campos A, Diema C, Omeñaca N, de Oliveira E, Guinovart J, Vilaseca M.
PMID: 21906361
Clin Proteomics. 2011 Jun 03;8(1):6. doi: 10.1186/1559-0275-8-6.

BACKGROUND: In cerebrospinal fluid (CSF), which is a rich source of biomarkers for neurological diseases, identification of biomarkers requires methods that allow reproducible detection of low abundance proteins. It is therefore crucial to decrease dynamic range and improve assessment...

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Borg J, Campos A, Diema C, et al. Spectral counting assessment of protein dynamic range in cerebrospinal fluid following depletion with plasma-designed immunoaffinity columns. Clin Proteomics. 2011;8(1):6doi: 10.1186/1559-0275-8-6.
Borg, J., Campos, A., Diema, C., Omeñaca, N., de Oliveira, E., Guinovart, J., & Vilaseca, M. (2011). Spectral counting assessment of protein dynamic range in cerebrospinal fluid following depletion with plasma-designed immunoaffinity columns. Clinical proteomics, 8(1), 6. https://doi.org/10.1186/1559-0275-8-6
Borg, Jacques, et al. "Spectral counting assessment of protein dynamic range in cerebrospinal fluid following depletion with plasma-designed immunoaffinity columns." Clinical proteomics vol. 8,1 (2011): 6. doi: https://doi.org/10.1186/1559-0275-8-6
Borg J, Campos A, Diema C, Omeñaca N, de Oliveira E, Guinovart J, Vilaseca M. Spectral counting assessment of protein dynamic range in cerebrospinal fluid following depletion with plasma-designed immunoaffinity columns. Clin Proteomics. 2011 Jun 03;8(1):6. doi: 10.1186/1559-0275-8-6. PMID: 21906361; PMCID: PMC3167203.
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Role of brain glycogen in the response to hypoxia and in susceptibility to epilepsy.

Frontiers in cellular neuroscience

López-Ramos JC, Duran J, Gruart A, Guinovart JJ, Delgado-García JM.
PMID: 26578889
Front Cell Neurosci. 2015 Oct 27;9:431. doi: 10.3389/fncel.2015.00431. eCollection 2015.

Although glycogen is the only carbohydrate reserve of the brain, its overall contribution to brain functions remains unclear. It has been proposed that glycogen participates in the preservation of such functions during hypoxia. Several reports also describe a relationship...

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López-Ramos JC, Duran J, Gruart A, et al. Role of brain glycogen in the response to hypoxia and in susceptibility to epilepsy. Front Cell Neurosci. 2015;9:431doi: 10.3389/fncel.2015.00431.
López-Ramos, J. C., Duran, J., Gruart, A., Guinovart, J. J., & Delgado-García, J. M. (2015). Role of brain glycogen in the response to hypoxia and in susceptibility to epilepsy. Frontiers in cellular neuroscience, 9431. https://doi.org/10.3389/fncel.2015.00431
López-Ramos, Juan C, et al. "Role of brain glycogen in the response to hypoxia and in susceptibility to epilepsy." Frontiers in cellular neuroscience vol. 9 (2015): 431. doi: https://doi.org/10.3389/fncel.2015.00431
López-Ramos JC, Duran J, Gruart A, Guinovart JJ, Delgado-García JM. Role of brain glycogen in the response to hypoxia and in susceptibility to epilepsy. Front Cell Neurosci. 2015 Oct 27;9:431. doi: 10.3389/fncel.2015.00431. eCollection 2015. PMID: 26578889; PMCID: PMC4621300.
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Evaluating the impact of programmatic mass drug administration for malaria in Zambia using routine incidence data.

The Journal of infectious diseases

Fraser M, Miller JM, Silumbe K, Hainsworth M, Mudenda M, Hamainza B, Moonga H, Chizema Kawesha E, Mercer LD, Bennett A, Schneider K, Slater HC, Eisele TP, Guinovart C.
PMID: 32691047
J Infect Dis. 2020 Jul 21; doi: 10.1093/infdis/jiaa434. Epub 2020 Jul 21.

BACKGROUND: In 2016, the Zambian National Malaria Elimination Centre started programmatic mass drug administration (pMDA) campaigns with dihydroartemisinin-piperaquine as a malaria elimination tool in Southern Province. Two rounds were administered, two months apart (coverage 70% and 57% respectively). We...

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Fraser M, Miller JM, Silumbe K, et al. Evaluating the impact of programmatic mass drug administration for malaria in Zambia using routine incidence data. J Infect Dis. 2020;doi: 10.1093/infdis/jiaa434.
Fraser, M., Miller, J. M., Silumbe, K., Hainsworth, M., Mudenda, M., Hamainza, B., Moonga, H., Chizema Kawesha, E., Mercer, L. D., Bennett, A., Schneider, K., Slater, H. C., Eisele, T. P., & Guinovart, C. (2020). Evaluating the impact of programmatic mass drug administration for malaria in Zambia using routine incidence data. The Journal of infectious diseases, . https://doi.org/10.1093/infdis/jiaa434
Fraser, Maya, et al. "Evaluating the impact of programmatic mass drug administration for malaria in Zambia using routine incidence data." The Journal of infectious diseases vol. (2020). doi: https://doi.org/10.1093/infdis/jiaa434
Fraser M, Miller JM, Silumbe K, Hainsworth M, Mudenda M, Hamainza B, Moonga H, Chizema Kawesha E, Mercer LD, Bennett A, Schneider K, Slater HC, Eisele TP, Guinovart C. Evaluating the impact of programmatic mass drug administration for malaria in Zambia using routine incidence data. J Infect Dis. 2020 Jul 21; doi: 10.1093/infdis/jiaa434. Epub 2020 Jul 21. PMID: 32691047.
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A biochemistry and molecular biology course for secondary school teachers*.

Biochemistry and molecular biology education : a bimonthly publication of the International Union of Biochemistry and Molecular Biology

Fernández-Novell JM, Cid E, Gomis R, Barberà A, Guinovart JJ.
PMID: 21706760
Biochem Mol Biol Educ. 2004 Nov;32(6):378-80. doi: 10.1002/bmb.2004.494032060409.

This article describes a course for reinforcing the knowledge of biochemistry in secondary school science teachers. The Department of Biochemistry and Molecular Biology of the University of Barcelona designed a course to bring these teachers up to date with...

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Fernández-Novell JM, Cid E, Gomis R, et al. A biochemistry and molecular biology course for secondary school teachers*. Biochem Mol Biol Educ. 2004;32(6):378-80doi: 10.1002/bmb.2004.494032060409.
Fernández-Novell, J. M., Cid, E., Gomis, R., Barberà, A., & Guinovart, J. J. (2004). A biochemistry and molecular biology course for secondary school teachers*. Biochemistry and molecular biology education : a bimonthly publication of the International Union of Biochemistry and Molecular Biology, 32(6), 378-80. https://doi.org/10.1002/bmb.2004.494032060409
Fernández-Novell, J M, et al. "A biochemistry and molecular biology course for secondary school teachers*." Biochemistry and molecular biology education : a bimonthly publication of the International Union of Biochemistry and Molecular Biology vol. 32,6 (2004): 378-80. doi: https://doi.org/10.1002/bmb.2004.494032060409
Fernández-Novell JM, Cid E, Gomis R, Barberà A, Guinovart JJ. A biochemistry and molecular biology course for secondary school teachers*. Biochem Mol Biol Educ. 2004 Nov;32(6):378-80. doi: 10.1002/bmb.2004.494032060409. PMID: 21706760.
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p38γ and p38δ regulate postnatal cardiac metabolism through glycogen synthase 1.

PLoS biology

Santamans AM, Montalvo-Romeral V, Mora A, Lopez JA, González-Romero F, Jimenez-Blasco D, Rodríguez E, Pintor-Chocano A, Casanueva-Benítez C, Acín-Pérez R, Leiva-Vega L, Duran J, Guinovart JJ, Jiménez-Borreguero J, Enríquez JA, Villlalba-Orero M, Bolaños JP, Aspichueta P, Vázquez J, González-Terán B, Sabio G.
PMID: 34758018
PLoS Biol. 2021 Nov 10;19(11):e3001447. doi: 10.1371/journal.pbio.3001447. eCollection 2021 Nov.

During the first weeks of postnatal heart development, cardiomyocytes undergo a major adaptive metabolic shift from glycolytic energy production to fatty acid oxidation. This metabolic change is contemporaneous to the up-regulation and activation of the p38γ and p38δ stress-activated...

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Santamans AM, Montalvo-Romeral V, Mora A, et al. p38γ and p38δ regulate postnatal cardiac metabolism through glycogen synthase 1. PLoS Biol. 2021;19(11):e3001447doi: 10.1371/journal.pbio.3001447.
Santamans, A. M., Montalvo-Romeral, V., Mora, A., Lopez, J. A., González-Romero, F., Jimenez-Blasco, D., Rodríguez, E., Pintor-Chocano, A., Casanueva-Benítez, C., Acín-Pérez, R., Leiva-Vega, L., Duran, J., Guinovart, J. J., Jiménez-Borreguero, J., Enríquez, J. A., Villlalba-Orero, M., Bolaños, J. P., Aspichueta, P., Vázquez, J., González-Terán, B., & Sabio, G. (2021). p38γ and p38δ regulate postnatal cardiac metabolism through glycogen synthase 1. PLoS biology, 19(11), e3001447. https://doi.org/10.1371/journal.pbio.3001447
Santamans, Ayelén M, et al. "p38γ and p38δ regulate postnatal cardiac metabolism through glycogen synthase 1." PLoS biology vol. 19,11 (2021): e3001447. doi: https://doi.org/10.1371/journal.pbio.3001447
Santamans AM, Montalvo-Romeral V, Mora A, Lopez JA, González-Romero F, Jimenez-Blasco D, Rodríguez E, Pintor-Chocano A, Casanueva-Benítez C, Acín-Pérez R, Leiva-Vega L, Duran J, Guinovart JJ, Jiménez-Borreguero J, Enríquez JA, Villlalba-Orero M, Bolaños JP, Aspichueta P, Vázquez J, González-Terán B, Sabio G. p38γ and p38δ regulate postnatal cardiac metabolism through glycogen synthase 1. PLoS Biol. 2021 Nov 10;19(11):e3001447. doi: 10.1371/journal.pbio.3001447. eCollection 2021 Nov. PMID: 34758018; PMCID: PMC8612745.
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p38γ and p38δ regulate postnatal cardiac metabolism through glycogen synthase 1.

PLoS biology

Santamans AM, Montalvo-Romeral V, Mora A, Lopez JA, González-Romero F, Jimenez-Blasco D, Rodríguez E, Pintor-Chocano A, Casanueva-Benítez C, Acín-Pérez R, Leiva-Vega L, Duran J, Guinovart JJ, Jiménez-Borreguero J, Enríquez JA, Villlalba-Orero M, Bolaños JP, Aspichueta P, Vázquez J, González-Terán B, Sabio G.
PMID: 34758018
PLoS Biol. 2021 Nov 10;19(11):e3001447. doi: 10.1371/journal.pbio.3001447. eCollection 2021 Nov.

During the first weeks of postnatal heart development, cardiomyocytes undergo a major adaptive metabolic shift from glycolytic energy production to fatty acid oxidation. This metabolic change is contemporaneous to the up-regulation and activation of the p38γ and p38δ stress-activated...

Cite
Santamans AM, Montalvo-Romeral V, Mora A, et al. p38γ and p38δ regulate postnatal cardiac metabolism through glycogen synthase 1. PLoS Biol. 2021;19(11):e3001447doi: 10.1371/journal.pbio.3001447.
Santamans, A. M., Montalvo-Romeral, V., Mora, A., Lopez, J. A., González-Romero, F., Jimenez-Blasco, D., Rodríguez, E., Pintor-Chocano, A., Casanueva-Benítez, C., Acín-Pérez, R., Leiva-Vega, L., Duran, J., Guinovart, J. J., Jiménez-Borreguero, J., Enríquez, J. A., Villlalba-Orero, M., Bolaños, J. P., Aspichueta, P., Vázquez, J., González-Terán, B., & Sabio, G. (2021). p38γ and p38δ regulate postnatal cardiac metabolism through glycogen synthase 1. PLoS biology, 19(11), e3001447. https://doi.org/10.1371/journal.pbio.3001447
Santamans, Ayelén M, et al. "p38γ and p38δ regulate postnatal cardiac metabolism through glycogen synthase 1." PLoS biology vol. 19,11 (2021): e3001447. doi: https://doi.org/10.1371/journal.pbio.3001447
Santamans AM, Montalvo-Romeral V, Mora A, Lopez JA, González-Romero F, Jimenez-Blasco D, Rodríguez E, Pintor-Chocano A, Casanueva-Benítez C, Acín-Pérez R, Leiva-Vega L, Duran J, Guinovart JJ, Jiménez-Borreguero J, Enríquez JA, Villlalba-Orero M, Bolaños JP, Aspichueta P, Vázquez J, González-Terán B, Sabio G. p38γ and p38δ regulate postnatal cardiac metabolism through glycogen synthase 1. PLoS Biol. 2021 Nov 10;19(11):e3001447. doi: 10.1371/journal.pbio.3001447. eCollection 2021 Nov. PMID: 34758018; PMCID: PMC8612745.
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Astrocytic glycogen accumulation drives the pathophysiology of neurodegeneration in Lafora disease.

Brain : a journal of neurology

Duran J, Hervera A, Markussen KH, Varea O, López-Soldado I, Sun RC, Del Río JA, Gentry MS, Guinovart JJ.
PMID: 33822008
Brain. 2021 Sep 04;144(8):2349-2360. doi: 10.1093/brain/awab110.

The hallmark of Lafora disease, a fatal neurodegenerative disorder, is the accumulation of intracellular glycogen aggregates called Lafora bodies. Until recently, it was widely believed that brain Lafora bodies were present exclusively in neurons and thus that Lafora disease...

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Duran J, Hervera A, Markussen KH, et al. Astrocytic glycogen accumulation drives the pathophysiology of neurodegeneration in Lafora disease. Brain. 2021;144(8):2349-2360doi: 10.1093/brain/awab110.
Duran, J., Hervera, A., Markussen, K. H., Varea, O., López-Soldado, I., Sun, R. C., Del Río, J. A., Gentry, M. S., & Guinovart, J. J. (2021). Astrocytic glycogen accumulation drives the pathophysiology of neurodegeneration in Lafora disease. Brain : a journal of neurology, 144(8), 2349-2360. https://doi.org/10.1093/brain/awab110
Duran, Jordi, et al. "Astrocytic glycogen accumulation drives the pathophysiology of neurodegeneration in Lafora disease." Brain : a journal of neurology vol. 144,8 (2021): 2349-2360. doi: https://doi.org/10.1093/brain/awab110
Duran J, Hervera A, Markussen KH, Varea O, López-Soldado I, Sun RC, Del Río JA, Gentry MS, Guinovart JJ. Astrocytic glycogen accumulation drives the pathophysiology of neurodegeneration in Lafora disease. Brain. 2021 Sep 04;144(8):2349-2360. doi: 10.1093/brain/awab110. PMID: 33822008; PMCID: PMC8418345.
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A reference electrode based on polyvinyl butyral (PVB) polymer for decentralized chemical measurements.

Analytica chimica acta

Guinovart T, Crespo GA, Rius FX, Andrade FJ.
PMID: 24703216
Anal Chim Acta. 2014 Apr 22;821:72-80. doi: 10.1016/j.aca.2014.02.028. Epub 2014 Feb 22.

A new solid-state reference electrode using a polymeric membrane of polyvinyl butyral (PVB), Ag/AgCl and NaCl to be used in decentralized chemical measurements is presented. The electrode is made by drop-casting the membrane cocktail onto a glassy carbon (GC)...

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Guinovart T, Crespo GA, Rius FX, et al. A reference electrode based on polyvinyl butyral (PVB) polymer for decentralized chemical measurements. Anal Chim Acta. 2014;821:72-80doi: 10.1016/j.aca.2014.02.028.
Guinovart, T., Crespo, G. A., Rius, F. X., & Andrade, F. J. (2014). A reference electrode based on polyvinyl butyral (PVB) polymer for decentralized chemical measurements. Analytica chimica acta, 82172-80. https://doi.org/10.1016/j.aca.2014.02.028
Guinovart, Tomàs, et al. "A reference electrode based on polyvinyl butyral (PVB) polymer for decentralized chemical measurements." Analytica chimica acta vol. 821 (2014): 72-80. doi: https://doi.org/10.1016/j.aca.2014.02.028
Guinovart T, Crespo GA, Rius FX, Andrade FJ. A reference electrode based on polyvinyl butyral (PVB) polymer for decentralized chemical measurements. Anal Chim Acta. 2014 Apr 22;821:72-80. doi: 10.1016/j.aca.2014.02.028. Epub 2014 Feb 22. PMID: 24703216.
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Shining the spotlight on education.

Biochemistry and molecular biology education : a bimonthly publication of the International Union of Biochemistry and Molecular Biology

Guinovart JJ.
PMID: 28509368
Biochem Mol Biol Educ. 2017 May;45(3):193. doi: 10.1002/bmb.21064.

No abstract available.

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Guinovart JJ. Shining the spotlight on education. Biochem Mol Biol Educ. 2017;45(3):193doi: 10.1002/bmb.21064.
Guinovart, J. J. (2017). Shining the spotlight on education. Biochemistry and molecular biology education : a bimonthly publication of the International Union of Biochemistry and Molecular Biology, 45(3), 193. https://doi.org/10.1002/bmb.21064
Guinovart, Joan J. "Shining the spotlight on education." Biochemistry and molecular biology education : a bimonthly publication of the International Union of Biochemistry and Molecular Biology vol. 45,3 (2017): 193. doi: https://doi.org/10.1002/bmb.21064
Guinovart JJ. Shining the spotlight on education. Biochem Mol Biol Educ. 2017 May;45(3):193. doi: 10.1002/bmb.21064. PMID: 28509368.
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Correction: Selective photoregulation of the activity of glycogen synthase and glycogen phosphorylase, two key enzymes in glycogen metabolism.

Organic & biomolecular chemistry

Díaz-Lobo M, Garcia-Amorós J, Fita I, Velasco D, Guinovart JJ, Ferrer JC.
PMID: 26375675
Org Biomol Chem. 2015 Oct 21;13(39):10072. doi: 10.1039/c5ob90155c.

Correction for 'Selective photoregulation of the activity of glycogen synthase and glycogen phosphorylase, two key enzymes in glycogen metabolism' by Mireia Díaz-Lobo, et al., Org. Biomol. Chem., 2015, 13, 7282-7288.

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Díaz-Lobo M, Garcia-Amorós J, Fita I, et al. Correction: Selective photoregulation of the activity of glycogen synthase and glycogen phosphorylase, two key enzymes in glycogen metabolism. Org Biomol Chem. 2015;13(39):10072doi: 10.1039/c5ob90155c.
Díaz-Lobo, M., Garcia-Amorós, J., Fita, I., Velasco, D., Guinovart, J. J., & Ferrer, J. C. (2015). Correction: Selective photoregulation of the activity of glycogen synthase and glycogen phosphorylase, two key enzymes in glycogen metabolism. Organic & biomolecular chemistry, 13(39), 10072. https://doi.org/10.1039/c5ob90155c
Díaz-Lobo, Mireia, et al. "Correction: Selective photoregulation of the activity of glycogen synthase and glycogen phosphorylase, two key enzymes in glycogen metabolism." Organic & biomolecular chemistry vol. 13,39 (2015): 10072. doi: https://doi.org/10.1039/c5ob90155c
Díaz-Lobo M, Garcia-Amorós J, Fita I, Velasco D, Guinovart JJ, Ferrer JC. Correction: Selective photoregulation of the activity of glycogen synthase and glycogen phosphorylase, two key enzymes in glycogen metabolism. Org Biomol Chem. 2015 Oct 21;13(39):10072. doi: 10.1039/c5ob90155c. PMID: 26375675.
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