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Showing 1 to 12 of 81 entries
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Hydrophilic interaction chromatography: A promising alternative to reversed-phase liquid chromatography systems for the purification of small protonated bases.

Journal of separation science

Gritti F, Guiochon G.
PMID: 25755153
J Sep Sci. 2015 May;38(10):1633-41. doi: 10.1002/jssc.201401351. Epub 2015 Apr 14.

The overloaded band profiles of the protonated species of propranolol and amitriptyline were recorded under acidic conditions on four classes of stationary phases including a conventional silica/organic hybrid material in reversed-phase liquid chromatography mode (BEH-C18), an electrostatic repulsion reversed-phase...

Accurate on-line mass flow measurements in supercritical fluid chromatography.

Journal of chromatography. A

Tarafder A, Vajda P, Guiochon G.
PMID: 24210558
J Chromatogr A. 2013 Dec 13;1320:130-7. doi: 10.1016/j.chroma.2013.10.041. Epub 2013 Oct 22.

This work demonstrates the possible advantages and the challenges of accurate on-line measurements of the CO2 mass flow rate during supercritical fluid chromatography (SFC) operations. Only the mass flow rate is constant along the column in SFC. The volume...

Thermodynamic interpretation of retention equilibrium in reversed-phase liquid chromatography based on enthalpy-entropy compensation.

Analytical chemistry

Miyabet K, Guiochon G.
PMID: 12498193
Anal Chem. 2002 Dec 01;74(23):5982-92. doi: 10.1021/ac0202233.

The fundamentals of the retention equilibrium in reversed-phase liquid chromatography (RPLC) are studied on the basis of enthalpy-entropy compensation (EEC). First, retention data were acquired and the influence of the nature of the compounds, organic solvent modifier, and temperature...

Analysis of the surface diffusion of alkylbenzenes and p-alkylphenols in reversed-phase liquid chromatography using the surface-restricted molecular diffusion model.

Analytical chemistry

Miyabe K, Guiochon G.
PMID: 11467559
Anal Chem. 2001 Jul 01;73(13):3096-106. doi: 10.1021/ac001477w.

Surface diffusion of alkylbenzene and p-alkylphenol derivatives was measured in reversed-phase liquid chromatography on a C18-silica column with a methanol/water mixture (70/30, v/v) as the mobile phase. They were analyzed on the basis of the restricted molecular diffusion model...

Modeling of the separation of the enantiomers of 1-phenyl-1-propanol on cellulose tribenzoate.

Analytical chemistry

Cavazzini A, Kaczmarski K, Szabelski P, Zhou D, Liu X, Guiochon GG.
PMID: 11774911
Anal Chem. 2001 Dec 01;73(23):5704-15. doi: 10.1021/ac010751z.

The competitive adsorption isotherms of rac-1-phenyl-1-propanol on cellulose tribenzoate were measured by competitive frontal analysis. The experimental data were fitted to four different isotherm models: Langmuir, Bilangmuir, Langmuir-Freundlich, and Tóth. The fittings of the experimental data to all four...

Restricted diffusion model for surface diffusion in reversed-phase liquid chromatography.

Analytical chemistry

Miyabe K, Guiochon G.
PMID: 10763243
Anal Chem. 2000 Apr 01;72(7):1475-89. doi: 10.1021/ac9909913.

The analysis of experimental results in reversed-phase liquid chromatography (RPLC) allows further discussion of the restricted diffusion model of surface diffusion formulated on the basis of the absolute rate theory. Chromatographic data were acquired on different RPLC systems with...

New thermodynamically consistent competitive adsorption isotherm in RPLC.

Journal of colloid and interface science

Gritti F, Guiochon G.
PMID: 12885518
J Colloid Interface Sci. 2003 Aug 01;264(1):43-59. doi: 10.1016/s0021-9797(03)00332-1.

A new equation of competitive isotherms was derived in the framework of the ideal adsorbed solution (IAS) that predicts multisolute adsorption isotherms from single-solute isotherms. The IAS theory makes this new isotherm thermodynamically consistent, whatever the saturation capacities of...

Moment analysis of mass-transfer kinetics in C18-silica monolithic columns.

Analytical chemistry

Miyabe K, Cavazzini A, Gritti F, Kele M, Guiochon G.
PMID: 14670061
Anal Chem. 2003 Dec 15;75(24):6975-86. doi: 10.1021/ac0302206.

The moment analysis of elution peak profiles based on new moment equations provides information on the mass-transfer characteristics of C(18)-silica monolithic columns. The flow rate dependence of the HETP data was analyzed using the generalized van Deemter equation, after...

Comparison of the thermodynamic properties of particulate and monolithic columns of molecularly imprinted copolymers.

Analytical chemistry

Kim H, Guiochon G.
PMID: 15623283
Anal Chem. 2005 Jan 01;77(1):93-102. doi: 10.1021/ac0401218.

A variety of polymerization techniques can be used to prepare molecularly imprinted copolymers (MIPs) for the purpose of the separation of enantiomers by HPLC. Unfortunately, the lack of thermodynamic and kinetic data characterizing the imprinted polymers prepared by these...

Peak parking-moment analysis. A strategy for the study of the mass-transfer kinetics in the stationary phase.

Analytical chemistry

Miyabe K, Matsumoto Y, Guiochon G.
PMID: 17269752
Anal Chem. 2007 Mar 01;79(5):1970-82. doi: 10.1021/ac061321h. Epub 2007 Feb 02.

The combination of peak parking and moment analysis is proved to be a powerful strategy for studying the molecular diffusivity of solute molecules in stationary phases and for determining the corresponding kinetic parameters. The physical meaning of the traditional...

Nonlinear chromatography Recent theoretical and experimental results.

Talanta

Guiochon G, Ghodbane S, Golshan-Shirazi S, Huang JX, Katti A, Lin BC, Ma Z.
PMID: 18964673
Talanta. 1989 Jan-Feb;36(1):19-33. doi: 10.1016/0039-9140(89)80079-7.

The theory of nonlinear chromatography has been advanced by the incorporation of recent results obtained by the theory of partial differential equations. The system of equations of the ideal model has been solved analytically in the case of a...

Peak shape distortions in the capillary electrophoretic separations of strong electrolytes when the background electrolyte contains two strong electrolyte co-ions.

Analytical chemistry

Williams RL, Childs B, Dose EV, Guiochon G, Vigh G.
PMID: 21639342
Anal Chem. 1997 Apr 01;69(7):1347-54. doi: 10.1021/ac9609337.

A series of 25 mM phosphate buffer background electrolytes were prepared from phosphoric acid and mixtures of lithium hydroxide and tetrabutylammonium hydroxide as pH adjusters and sources of background electrolyte co-ions. These background electrolytes were used for the capillary...

Showing 1 to 12 of 81 entries