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Showing 1 to 12 of 29 entries
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Factors Associated With Rebound Hyperthermia After Targeted Temperature Management in Out-of-Hospital Cardiac Arrest Patients: An Explorative Substudy of the Time-Differentiated Therapeutic Hypothermia in Out-of-Hospital Cardiac Arrest Survivors Trial.

Critical care explorations

Holm A, Kirkegaard H, Taccone FS, Søreide E, Grejs AM, Toome V, Hassager C, Rasmussen BS, Laitio T, Storm C, Hästbacka J, Skrifvars MB.
PMID: 34250498
Crit Care Explor. 2021 Jul 06;3(7):e0458. doi: 10.1097/CCE.0000000000000458. eCollection 2021 Jul.

To investigate rebound hyperthermia following targeted temperature management after cardiac arrest and its impact on functional outcome.DESIGN: Post hoc analysis.SETTING: Ten European ICUs.PATIENTS: Patients included in the time-differentiated therapeutic hypothermia in out-of-hospital cardiac arrest survivors trial treated with targeted...

APOE ε4 associates with increased risk of severe COVID-19, cerebral microhaemorrhages and post-COVID mental fatigue: a Finnish biobank, autopsy and clinical study.

Acta neuropathologica communications

Kurki SN, Kantonen J, Kaivola K, Hokkanen L, Mäyränpää MI, Puttonen H, Martola J, Pöyhönen M, Kero M, Tuimala J, Carpén O, Kantele A, Vapalahti O, Tiainen M, Tienari PJ, Kaila K, Hästbacka J, Myllykangas L.
PMID: 34949230
Acta Neuropathol Commun. 2021 Dec 23;9(1):199. doi: 10.1186/s40478-021-01302-7.

Apolipoprotein E ε4 allele (APOE4) has been shown to associate with increased susceptibility to SARS-CoV-2 infection and COVID-19 mortality in some previous genetic studies, but information on the role of APOE4 on the underlying pathology and parallel clinical manifestations...

Estimation of Arterial Carbon Dioxide Based on End-Tidal Gas Pressure and Oxygen Saturation.

Journal of clinical medicine

Rentola R, Hästbacka J, Heinonen E, Rosenberg PH, Häggblom T, Skrifvars MB.
PMID: 30235787
J Clin Med. 2018 Sep 19;7(9). doi: 10.3390/jcm7090290.

Arterial blood gas (ABG) analysis is the traditional method for measuring the partial pressure of carbon dioxide. In mechanically ventilated patients a continuous noninvasive monitoring of

A combination of fluorescent probes for evaluation of cytotoxicity and toxic mechanisms in isolated rainbow trout hepatocytes.

Toxicology in vitro : an international journal published in association with BIBRA

Lilius H, Hästbacka T, Isomaa B.
PMID: 20650214
Toxicol In Vitro. 1996 Jun;10(3):341-8. doi: 10.1016/0887-2333(96)00015-x.

The toxicity of 17 chemicals to freshly isolated rainbow trout hepatocytes was determined using four different fluorescent probes measuring different endpoints. Calcein was used to determine viability of the cells, rhodamine 123 and 5,5',6,6'-tetrachloro-1,1',3,3'-tetraethylbenzimidazolylcarbocyanine iodide (JC-1) to monitor mitochondrial...

GFAp and tau protein as predictors of neurological outcome after out-of-hospital cardiac arrest: A post hoc analysis of the COMACARE trial.

Resuscitation

Humaloja J, Lähde M, Ashton NJ, Matti R, Hästbacka J, Jakkula P, Friberg H, Cronberg T, Pettilä V, Blennow K, Zetterberg H, Skrifvars MB.
PMID: 34863908
Resuscitation. 2021 Dec 01;170:141-149. doi: 10.1016/j.resuscitation.2021.11.033. Epub 2021 Dec 01.

AIM: To determine the ability of serum glial fibrillary acidic protein (GFAp) and tau protein to predict neurological outcome after out-of-hospital cardiac arrest (OHCA).METHODS: We measured plasma concentrations of GFAp and tau of patients included in the previously published...

A descriptive study of the surge response and outcomes of ICU patients with COVID-19 during first wave in Nordic countries.

Acta anaesthesiologica Scandinavica

Chew MS, Kattainen S, Haase N, Buanes EA, Kristinsdottir LB, Hofsø K, Laake JH, Kvåle R, Hästbacka J, Reinikainen M, Bendel S, Varpula T, Walther S, Perner A, Flaatten HK, Sigurdsson MI.
PMID: 34570897
Acta Anaesthesiol Scand. 2022 Jan;66(1):56-64. doi: 10.1111/aas.13983. Epub 2021 Oct 03.

BACKGROUND: We sought to provide a description of surge response strategies and characteristics, clinical management and outcomes of patients with severe COVID-19 in the intensive care unit (ICU) during the first wave of the pandemic in Denmark, Finland, Iceland,...

Management of acute atrial fibrillation in the intensive care unit: an international survey.

Acta anaesthesiologica Scandinavica

Wetterslev M, Møller MH, Granholm A, Hassager C, Haase N, Naz Aslam T, Shen J, Young PJ, Aneman A, Hästbacka J, Siegemund M, Cronhjort M, Lindqvist E, Myatra SN, Kalvit K, Arabi YM, Szczeklik W, Sigurdsson MI, Balik M, Keus F, Perner A.
PMID: 34870855
Acta Anaesthesiol Scand. 2021 Dec 06; doi: 10.1111/aas.14007. Epub 2021 Dec 06.

BACKGROUND: Atrial fibrillation (AF) is common in intensive care unit (ICU) patients and associated with poor outcomes. Different management strategies exist, but the evidence is limited and derived from non-ICU patients. This international survey of ICU doctors evaluated the...

Association between first language and SARS-CoV-2 infection rates, hospitalization, intensive care admissions and death in Finland: a population-based observational cohort study.

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases

Holmberg V, Salmi H, Kattainen S, Ollgren J, Kantele A, Pynnönen J, Järvinen A, Forsblom E, Silén S, Kivivuori SM, Meretoja A, Hästbacka J.
PMID: 34949510
Clin Microbiol Infect. 2022 Jan;28(1):107-113. doi: 10.1016/j.cmi.2021.08.022. Epub 2021 Sep 30.

OBJECTIVES: Motivated by reports of increased risk of coronavirus disease 2019 (COVID-19) in ethnic minorities of high-income countries, we explored whether patients with a foreign first language are at an increased risk of COVID-19 infections, more serious presentations, or...

Premorbid functional status as an outcome predictor in intensive care patients aged over 85 years.

BMC geriatrics

Pietiläinen L, Bäcklund M, Hästbacka J, Reinikainen M.
PMID: 35012458
BMC Geriatr. 2022 Jan 10;22(1):38. doi: 10.1186/s12877-021-02746-1.

BACKGROUND: Poor premorbid functional status (PFS) is associated with mortality after intensive care unit (ICU) admission in patients aged 80 years or older. In the subgroup of very old ICU patients, the ability to recover from critical illness varies...

Overlooking the Obvious during the COVID-19 Pandemic: Dyspnoea with Asymmetric Breath Sounds in a Toddler.

Case reports in pediatrics

Salmi H, Harve-Rytsälä H, Rautiainen P, Pyörälä S, Hästbacka J.
PMID: 33585047
Case Rep Pediatr. 2021 Feb 02;2021:8855962. doi: 10.1155/2021/8855962. eCollection 2021.

BACKGROUND: Paediatric healthcare specialists are concerned about the secondary effects of the COVID-19 pandemic on children. We report a case of acute respiratory distress in a healthy toddler whose healthcare providers were sidetracked from the correct diagnosis by suspicion...

GFAp and tau protein as predictors of neurological outcome after out-of-hospital cardiac arrest: A post hoc analysis of the COMACARE trial.

Resuscitation

Humaloja J, Lähde M, Ashton NJ, Matti R, Hästbacka J, Jakkula P, Friberg H, Cronberg T, Pettilä V, Blennow K, Zetterberg H, Skrifvars MB.
PMID: 34863908
Resuscitation. 2021 Dec 01;170:141-149. doi: 10.1016/j.resuscitation.2021.11.033. Epub 2021 Dec 01.

AIM: To determine the ability of serum glial fibrillary acidic protein (GFAp) and tau protein to predict neurological outcome after out-of-hospital cardiac arrest (OHCA).METHODS: We measured plasma concentrations of GFAp and tau of patients included in the previously published...

GFAp and tau protein as predictors of neurological outcome after out-of-hospital cardiac arrest: A post hoc analysis of the COMACARE trial.

Resuscitation

Humaloja J, Lähde M, Ashton NJ, Matti R, Hästbacka J, Jakkula P, Friberg H, Cronberg T, Pettilä V, Blennow K, Zetterberg H, Skrifvars MB.
PMID: 34863908
Resuscitation. 2021 Dec 01;170:141-149. doi: 10.1016/j.resuscitation.2021.11.033. Epub 2021 Dec 01.

AIM: To determine the ability of serum glial fibrillary acidic protein (GFAp) and tau protein to predict neurological outcome after out-of-hospital cardiac arrest (OHCA).METHODS: We measured plasma concentrations of GFAp and tau of patients included in the previously published...

Showing 1 to 12 of 29 entries