Advanced Search
Display options
Filter resources
Text Availability
Article type
Publication date
Species
Language
Sex
Age
Showing 1 to 12 of 38 entries
Sorted by: Best Match Show Resources per page
Folfirinox .

Therapeutic advances in gastroenterology

Williet N, Saint A, Pointet AL, Tougeron D, Pernot S, Pozet A, Bechade D, Trouilloud I, Lourenco N, Hautefeuille V, Locher C, Desrame J, Artru P, Thirot Bidault A, Le Roy B, Pezet D, Phelip JM, Taieb J.
PMID: 31598136
Therap Adv Gastroenterol. 2019 Sep 25;12:1756284819878660. doi: 10.1177/1756284819878660. eCollection 2019.

BACKGROUND: Folfirinox (FFX) and gemcitabine/nab-paclitaxel (GN) are both standard first-line treatments in patients with metastatic pancreatic cancer (mPC). However, data comparing these two chemotherapeutic regimens and their sequential use remain scarce.METHODS: Data from two independent cohorts enrolling patients treated...

Pembrolizumab with Capox Bevacizumab in patients with microsatellite stable metastatic colorectal cancer and a high immune infiltrate: The FFCD 1703-POCHI trial.

Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver

Gallois C, Emile JF, Kim S, Monterymard C, Gilabert M, Bez J, Lièvre A, Dahan L, Laurent-Puig P, Mineur L, Coriat R, Legoux JL, Hautefeuille V, Phelip JM, Lecomte T, Sokol H, Capron C, Randrian V, Lepage C, Lomenie N, Kurtz C, Taieb J, Tougeron D.
PMID: 34215534
Dig Liver Dis. 2021 Oct;53(10):1254-1259. doi: 10.1016/j.dld.2021.06.009. Epub 2021 Jun 30.

Pembrolizumab, a PD1 immune checkpoint inhibitor (ICI), was recently reported to be very effective in patients with microsatellite instable/deficient mismatch repair metastatic colorectal cancer (MSI/dMMR mCRC), unlike patients with microsatellite stable/proficient MMR (MSS/pMMR) mCRC, in whom ICIs are generally...

Three-Dimensional Porous Scaffolds Derived from Bovine Cancellous Bone Matrix Promote Osteoinduction, Osteoconduction, and Osteogenesis.

Polymers

Malagón-Escandón A, Hautefeuille M, Jimenez-Díaz E, Arenas-Alatorre J, Saniger JM, Badillo-Ramírez I, Vazquez N, Piñón-Zarate G, Castell-Rodríguez A.
PMID: 34960941
Polymers (Basel). 2021 Dec 15;13(24). doi: 10.3390/polym13244390.

The use of three-dimensional porous scaffolds derived from decellularized extracellular matrix (ECM) is increasing for functional repair and regeneration of injured bone tissue. Because these scaffolds retain their native structures and bioactive molecules, in addition to showing low immunogenicity...

On the formation of Friedlander waves in a compressed-gas-driven shock tube.

Proceedings. Mathematical, physical, and engineering sciences

Tasissa AF, Hautefeuille M, Fitek JH, Radovitzky RA.
PMID: 27118888
Proc Math Phys Eng Sci. 2016 Feb;472(2186):20150611. doi: 10.1098/rspa.2015.0611.

Compressed-gas-driven shock tubes have become popular as a laboratory-scale replacement for field blast tests. The well-known initial structure of the Riemann problem eventually evolves into a shock structure thought to resemble a Friedlander wave, although this remains to be...

Optimizing antimicrobial therapy in critically ill patients.

Infection and drug resistance

Vitrat V, Hautefeuille S, Janssen C, Bougon D, Sirodot M, Pagani L.
PMID: 25349478
Infect Drug Resist. 2014 Oct 20;7:261-71. doi: 10.2147/IDR.S44357. eCollection 2014.

Critically ill patients with infection in the intensive care unit (ICU) would certainly benefit from timely bacterial identification and effective antimicrobial treatment. Diagnostic techniques have clearly improved in the last years and allow earlier identification of bacterial strains in...

Cell Culture Platforms with Controllable Stiffness for Chick Embryonic Cardiomyocytes.

Biomimetics (Basel, Switzerland)

Durán-Pastén ML, Cortes D, Valencia-Amaya AE, King S, González-Gómez GH, Hautefeuille M.
PMID: 31105218
Biomimetics (Basel). 2019 Apr 27;4(2). doi: 10.3390/biomimetics4020033.

For several years, cell culture techniques have been physiologically relevant to understand living organisms both structurally and functionally, aiming at preserving as carefully as possible the in vivo integrity and function of the cells. However, when studying cardiac cells,...

Controlled Solvent-Free Formation of Embedded PDMS-Derived Carbon Nanodomains with Tunable Fluorescence Using Selective Laser Ablation with A Low-Power CD Laser.

Micromachines

González-Vázquez MJ, Hautefeuille M.
PMID: 30400500
Micromachines (Basel). 2017 Oct 17;8(10). doi: 10.3390/mi8100307.

We present a study of the application of a single-step and solvent-free laser-based strategy to control the formation of polymer-derived fluorescent carbon nanodomains embedded in poly-dimethylsiloxane (PDMS) microchannels. A low-power, laser-induced microplasma was used to produce a localised combustion...

Feasibility study and direct extraction of endogenous free metallic cations combining hemodialysis and chelating polymer.

Scientific reports

Natuzzi M, Grange C, Gréa T, Brichart T, Aigle A, Bechet D, Hautefeuille B, Thomas E, Ayoub JY, Bonnet JM, Louzier V, Allaouchiche B, Couturier A, Montembault A, de Oliveira PN, David L, Lux F, Tillement O.
PMID: 34620952
Sci Rep. 2021 Oct 07;11(1):19948. doi: 10.1038/s41598-021-99462-y.

In this article, we report the conception and the use of dialysis-based medical device for the extraction of metals. The medical device is obtained by addition in the dialysate of a functionalized chitosan that can chelate endogenous metals like...

Progress on the Use of Commercial Digital Optical Disc Units for Low-Power Laser Micromachining in Biomedical Applications.

Micromachines

Cruz-Ramírez A, Sánchez-Olvera R, Zamarrón-Hernández D, Hautefeuille M, Cabriales L, Jiménez-Díaz E, Díaz-Bello B, López-Aparicio J, Pérez-Calixto D, Cano-Jorge M, Vázquez-Victorio G.
PMID: 30424120
Micromachines (Basel). 2018 Apr 16;9(4). doi: 10.3390/mi9040187.

The development of organ-on-chip and biological scaffolds is currently requiring simpler methods for microstructure biocompatible materials in three dimensions, to fabricate structural and functional elements in biomaterials, or modify the physicochemical properties of desired substrates. Aiming at addressing this...

FOLFIRINEC: a randomized phase II trial of mFOLFIRINOX vs platinum-etoposide for metastatic neuroendocrine carcinoma of gastroenteropancreatic or unknown origin.

Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver

Hadoux J, Afchain P, Walter T, Tougeron D, Hautefeuille V, Monterymard C, Lorgis V, Thuillier F, Baudin E, Scoazec JY, Lepage C, Desgrippes R.
PMID: 33994125
Dig Liver Dis. 2021 Jul;53(7):824-829. doi: 10.1016/j.dld.2021.04.016. Epub 2021 May 12.

BACKGROUND: Poorly differentiated neuroendocrine carcinomas (NEC) are rare diseases with a poor prognosis. Platinum-etoposide (PE) has been the recommended first-line treatment for decades. FOLFIRINEC (NCT04325425) is a national multicenter randomized phase II study which aims to challenge this standard...

Determination by Relaxation Tests of the Mechanical Properties of Soft Polyacrylamide Gels Made for Mechanobiology Studies.

Polymers

Pérez-Calixto D, Amat-Shapiro S, Zamarrón-Hernández D, Vázquez-Victorio G, Puech PH, Hautefeuille M.
PMID: 33672475
Polymers (Basel). 2021 Feb 20;13(4). doi: 10.3390/polym13040629.

Following the general aim of recapitulating the native mechanical properties of tissues and organs in vitro, the field of materials science and engineering has benefited from recent progress in developing compliant substrates with physical and chemical properties similar to...

Metastatic colorectal carcinoma with signet-ring cells: Clinical, histological and molecular description from an Association des Gastro-Entérologues Oncologues (AGEO) French multicenter retrospective cohort.

Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver

Allart M, Leroy F, Kim S, Sefrioui D, Nayeri M, Zaanan A, Rousseau B, Ben Abdelghani M, de la Fouchardière C, Cacheux W, Legros R, Louafi S, Tougeron D, Bouché O, Fares N, Roquin G, Bignon AL, Maillet M, Pozet A, Hautefeuille V.
PMID: 34384712
Dig Liver Dis. 2021 Aug 09; doi: 10.1016/j.dld.2021.06.031. Epub 2021 Aug 09.

BACKGROUND: Metastatic signet-ring cell colorectal carcinoma is rare. We analyzed its clinicopathological and molecular features, prognostic factors and chemosensitivity.METHODS: Retrospective study from 2003 to 2017 in 31 French centers, divided into three groups: curative care (G1), chemotherapy alone (G2),...

Showing 1 to 12 of 38 entries