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Status of the mdm-2 and waf-1 genes in mouse epidermal jb6 variants harboring wild-type p53 - a p53-independent induction of waf-1.

International journal of oncology

Sun Y, Dong Z, Jackman J, Hegamyer G, Kim H, Colburn N.
PMID: 21556561
Int J Oncol. 1995 Feb;6(2):465-71. doi: 10.3892/ijo.6.2.465.

Mutational inactivation of the p53 tumor suppressor gene has been found not to be involved in preneoplastic-to-neoplastic progression in mouse JB6 variants. To examine the role of an inactivated p53 pathway in this tumor promotion/progression model, we have studied...

Showing 1 to 1 of 1 entries