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Showing 1 to 12 of 116 entries
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Establishing Specific Pathogen-Free (SPF) Nonhuman Primate Colonies.

ILAR journal

Buchl SJ, Keeling ME, Voss WR.
PMID: 11528043
ILAR J. 1997;38(1):22-27. doi: 10.1093/ilar.38.1.22.

No abstract available.

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Buchl SJ, Keeling ME, Voss WR. Establishing Specific Pathogen-Free (SPF) Nonhuman Primate Colonies. ILAR J. 1997;38(1):22-27doi: 10.1093/ilar.38.1.22.
Buchl, S. J., Keeling, M. E., & Voss, W. R. (1997). Establishing Specific Pathogen-Free (SPF) Nonhuman Primate Colonies. ILAR journal, 38(1), 22-27. https://doi.org/10.1093/ilar.38.1.22
Buchl, Stephanie J., et al. "Establishing Specific Pathogen-Free (SPF) Nonhuman Primate Colonies." ILAR journal vol. 38,1 (1997): 22-27. doi: https://doi.org/10.1093/ilar.38.1.22
Buchl SJ, Keeling ME, Voss WR. Establishing Specific Pathogen-Free (SPF) Nonhuman Primate Colonies. ILAR J. 1997;38(1):22-27. doi: 10.1093/ilar.38.1.22. PMID: 11528043.
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Glenohumeral Stiffness Response Between Men and Women for Anterior, Posterior, and Inferior Translation.

Journal of athletic training

Borsa PA, Sauers EL, Herling DE.
PMID: 12937579
J Athl Train. 2002 Sep;37(3):240-245.

OBJECTIVE: To quantify and compare the glenohumeral stiffness response in anterior-directed, posterior-directed, and inferior-directed translations in healthy men and women. DESIGN AND SETTING: We used a 2 division on times 3 factorial design and employed a device capable of...

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Borsa PA, Sauers EL, Herling DE. Glenohumeral Stiffness Response Between Men and Women for Anterior, Posterior, and Inferior Translation. J Athl Train. 2002;37(3):240-245
Borsa, P. A., Sauers, E. L., & Herling, D. E. (2002). Glenohumeral Stiffness Response Between Men and Women for Anterior, Posterior, and Inferior Translation. Journal of athletic training, 37(3), 240-245.
Borsa, Paul A, et al. "Glenohumeral Stiffness Response Between Men and Women for Anterior, Posterior, and Inferior Translation." Journal of athletic training vol. 37,3 (2002): 240-245.
Borsa PA, Sauers EL, Herling DE. Glenohumeral Stiffness Response Between Men and Women for Anterior, Posterior, and Inferior Translation. J Athl Train. 2002 Sep;37(3):240-245. PMID: 12937579; PMCID: PMC164350.
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Characterization of chemical speciation in ultrathin uranium oxide layered films.

Analytical chemistry

He H, Wang P, Allred DD, Majewski J, Wilkerson MP, Rector KD.
PMID: 23131069
Anal Chem. 2012 Dec 04;84(23):10380-7. doi: 10.1021/ac302598r. Epub 2012 Nov 15.

A unique approach to detect chemical speciation and distribution on nanometer-scale nuclear materials has been achieved by the combination of neutron reflectometry and shell-isolated surface-enhanced Raman spectroscopy. Both surface and underlying layers of the uranium oxide materials were determined...

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He H, Wang P, Allred DD, et al. Characterization of chemical speciation in ultrathin uranium oxide layered films. Anal Chem. 2012;84(23):10380-7doi: 10.1021/ac302598r.
He, H., Wang, P., Allred, D. D., Majewski, J., Wilkerson, M. P., & Rector, K. D. (2012). Characterization of chemical speciation in ultrathin uranium oxide layered films. Analytical chemistry, 84(23), 10380-7. https://doi.org/10.1021/ac302598r
He, Heming, et al. "Characterization of chemical speciation in ultrathin uranium oxide layered films." Analytical chemistry vol. 84,23 (2012): 10380-7. doi: https://doi.org/10.1021/ac302598r
He H, Wang P, Allred DD, Majewski J, Wilkerson MP, Rector KD. Characterization of chemical speciation in ultrathin uranium oxide layered films. Anal Chem. 2012 Dec 04;84(23):10380-7. doi: 10.1021/ac302598r. Epub 2012 Nov 15. PMID: 23131069.
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Detection of Circulating Tumor DNA in Patients With Leiomyosarcoma With Progressive Disease.

JCO precision oncology

Hemming ML, Klega KS, Rhoades J, Ha G, Acker KE, Andersen JL, Thai E, Nag A, Thorner AR, Raut CP, George S, Crompton BD.
PMID: 30793095
JCO Precis Oncol. 2019;2019. doi: 10.1200/PO.18.00235. Epub 2019 Jan 24.

PURPOSE: Leiomyosarcoma (LMS) is a soft tissue sarcoma characterized by multiple copy number alterations (CNAs) and without common recurrent single nucleotide variants. We evaluated the feasibility of detecting circulating tumor DNA (ctDNA) with next-generation sequencing in a cohort of...

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Hemming ML, Klega KS, Rhoades J, et al. Detection of Circulating Tumor DNA in Patients With Leiomyosarcoma With Progressive Disease. JCO Precis Oncol. 2019;2019doi: 10.1200/PO.18.00235.
Hemming, M. L., Klega, K. S., Rhoades, J., Ha, G., Acker, K. E., Andersen, J. L., Thai, E., Nag, A., Thorner, A. R., Raut, C. P., George, S., & Crompton, B. D. (2019). Detection of Circulating Tumor DNA in Patients With Leiomyosarcoma With Progressive Disease. JCO precision oncology, 2019. https://doi.org/10.1200/PO.18.00235
Hemming, Matthew L, et al. "Detection of Circulating Tumor DNA in Patients With Leiomyosarcoma With Progressive Disease." JCO precision oncology vol. 2019 (2019). doi: https://doi.org/10.1200/PO.18.00235
Hemming ML, Klega KS, Rhoades J, Ha G, Acker KE, Andersen JL, Thai E, Nag A, Thorner AR, Raut CP, George S, Crompton BD. Detection of Circulating Tumor DNA in Patients With Leiomyosarcoma With Progressive Disease. JCO Precis Oncol. 2019;2019. doi: 10.1200/PO.18.00235. Epub 2019 Jan 24. PMID: 30793095; PMCID: PMC6380497.
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The dawn of a new era in treating T-PLL.

Oncotarget

Schrader A, Braun T, Herling M.
PMID: 30774758
Oncotarget. 2019 Jan 18;10(6):626-628. doi: 10.18632/oncotarget.26595. eCollection 2019 Jan 18.

No abstract available.

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Schrader A, Braun T, Herling M. The dawn of a new era in treating T-PLL. Oncotarget. 2019;10(6):626-628doi: 10.18632/oncotarget.26595.
Schrader, A., Braun, T., & Herling, M. (2019). The dawn of a new era in treating T-PLL. Oncotarget, 10(6), 626-628. https://doi.org/10.18632/oncotarget.26595
Schrader, Alexandra, et al. "The dawn of a new era in treating T-PLL." Oncotarget vol. 10,6 (2019): 626-628. doi: https://doi.org/10.18632/oncotarget.26595
Schrader A, Braun T, Herling M. The dawn of a new era in treating T-PLL. Oncotarget. 2019 Jan 18;10(6):626-628. doi: 10.18632/oncotarget.26595. eCollection 2019 Jan 18. PMID: 30774758; PMCID: PMC6363017.
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Micro-RNA networks in T-cell prolymphocytic leukemia reflect T-cell activation and shape DNA damage response and survival pathways.

Haematologica

Braun T, Glass M, Wahnschaffe L, Otte M, Mayer P, Franitza M, Altmüller J, Hallek M, Hüttelmaier S, Schrader A, Herling M.
PMID: 33543866
Haematologica. 2022 Jan 01;107(1):187-200. doi: 10.3324/haematol.2020.267500.

T-cell prolymphocytic leukemia (T-PLL) is a poor-prognostic mature T-cell malignancy. It typically presents with exponentially rising lymphocyte counts, splenomegaly, and bone marrow infiltration. Effective treatment options are scarce and a better understanding of TPLL's pathogenesis is desirable. Activation of...

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Braun T, Glass M, Wahnschaffe L, et al. Micro-RNA networks in T-cell prolymphocytic leukemia reflect T-cell activation and shape DNA damage response and survival pathways. Haematologica. 2022;107(1):187-200doi: 10.3324/haematol.2020.267500.
Braun, T., Glass, M., Wahnschaffe, L., Otte, M., Mayer, P., Franitza, M., Altmüller, J., Hallek, M., Hüttelmaier, S., Schrader, A., & Herling, M. (2022). Micro-RNA networks in T-cell prolymphocytic leukemia reflect T-cell activation and shape DNA damage response and survival pathways. Haematologica, 107(1), 187-200. https://doi.org/10.3324/haematol.2020.267500
Braun, Till, et al. "Micro-RNA networks in T-cell prolymphocytic leukemia reflect T-cell activation and shape DNA damage response and survival pathways." Haematologica vol. 107,1 (2022): 187-200. doi: https://doi.org/10.3324/haematol.2020.267500
Braun T, Glass M, Wahnschaffe L, Otte M, Mayer P, Franitza M, Altmüller J, Hallek M, Hüttelmaier S, Schrader A, Herling M. Micro-RNA networks in T-cell prolymphocytic leukemia reflect T-cell activation and shape DNA damage response and survival pathways. Haematologica. 2022 Jan 01;107(1):187-200. doi: 10.3324/haematol.2020.267500. PMID: 33543866.
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Identification and Therapeutic Targeting of GPR20, Selectively Expressed in Gastrointestinal Stromal Tumors, with DS-6157a, a First-in-Class Antibody-Drug Conjugate.

Cancer discovery

Iida K, Abdelhamid Ahmed AH, Nagatsuma AK, Shibutani T, Yasuda S, Kitamura M, Hattori C, Abe M, Hasegawa J, Iguchi T, Karibe T, Nakada T, Inaki K, Kamei R, Abe Y, Nomura T, Andersen JL, Santagata S, Hemming ML, George S, Doi T, Ochiai A, Demetri GD, Agatsuma T.
PMID: 33579785
Cancer Discov. 2021 Jun;11(6):1508-1523. doi: 10.1158/2159-8290.CD-20-1434. Epub 2021 Feb 12.

Currently, the only approved treatments for gastrointestinal stromal tumor (GIST) are tyrosine kinase inhibitors (TKI), which eventually lead to the development of secondary resistance mutations in KIT or PDGFRA and disease progression. Herein, we identified G protein-coupled receptor 20...

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Iida K, Abdelhamid Ahmed AH, Nagatsuma AK, et al. Identification and Therapeutic Targeting of GPR20, Selectively Expressed in Gastrointestinal Stromal Tumors, with DS-6157a, a First-in-Class Antibody-Drug Conjugate. Cancer Discov. 2021;11(6):1508-1523doi: 10.1158/2159-8290.CD-20-1434.
Iida, K., Abdelhamid Ahmed, A. H., Nagatsuma, A. K., Shibutani, T., Yasuda, S., Kitamura, M., Hattori, C., Abe, M., Hasegawa, J., Iguchi, T., Karibe, T., Nakada, T., Inaki, K., Kamei, R., Abe, Y., Nomura, T., Andersen, J. L., Santagata, S., Hemming, M. L., George, S., Doi, T., Ochiai, A., Demetri, G. D., & Agatsuma, T. (2021). Identification and Therapeutic Targeting of GPR20, Selectively Expressed in Gastrointestinal Stromal Tumors, with DS-6157a, a First-in-Class Antibody-Drug Conjugate. Cancer discovery, 11(6), 1508-1523. https://doi.org/10.1158/2159-8290.CD-20-1434
Iida, Kenji, et al. "Identification and Therapeutic Targeting of GPR20, Selectively Expressed in Gastrointestinal Stromal Tumors, with DS-6157a, a First-in-Class Antibody-Drug Conjugate." Cancer discovery vol. 11,6 (2021): 1508-1523. doi: https://doi.org/10.1158/2159-8290.CD-20-1434
Iida K, Abdelhamid Ahmed AH, Nagatsuma AK, Shibutani T, Yasuda S, Kitamura M, Hattori C, Abe M, Hasegawa J, Iguchi T, Karibe T, Nakada T, Inaki K, Kamei R, Abe Y, Nomura T, Andersen JL, Santagata S, Hemming ML, George S, Doi T, Ochiai A, Demetri GD, Agatsuma T. Identification and Therapeutic Targeting of GPR20, Selectively Expressed in Gastrointestinal Stromal Tumors, with DS-6157a, a First-in-Class Antibody-Drug Conjugate. Cancer Discov. 2021 Jun;11(6):1508-1523. doi: 10.1158/2159-8290.CD-20-1434. Epub 2021 Feb 12. PMID: 33579785.
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Utility of transesophageal echocardiography in the identification and treatment of occult mechanisms of cerebral infarction.

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia

Heslin ME, Thon JM, Caruso E, Romiyo P, Rana A, Yu S, Thau L, Rana A, Kamen S, Siegler JE.
PMID: 34929648
J Clin Neurosci. 2021 Dec 03;95:31-37. doi: 10.1016/j.jocn.2021.10.020. Epub 2021 Dec 03.

Cryptogenic stroke comprises approximately 25% of all cases of ischemic stroke. The diagnostic evaluation of these patients remains a challenge in clinical practice. Transesophageal echocardiography (TEE) has been shown to have superior diagnostic accuracy in identifying potential cardioembolic sources...

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Heslin ME, Thon JM, Caruso E, et al. Utility of transesophageal echocardiography in the identification and treatment of occult mechanisms of cerebral infarction. J Clin Neurosci. 2021;95:31-37doi: 10.1016/j.jocn.2021.10.020.
Heslin, M. E., Thon, J. M., Caruso, E., Romiyo, P., Rana, A., Yu, S., Thau, L., Rana, A., Kamen, S., & Siegler, J. E. (2021). Utility of transesophageal echocardiography in the identification and treatment of occult mechanisms of cerebral infarction. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 9531-37. https://doi.org/10.1016/j.jocn.2021.10.020
Heslin, Mark E, et al. "Utility of transesophageal echocardiography in the identification and treatment of occult mechanisms of cerebral infarction." Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia vol. 95 (2021): 31-37. doi: https://doi.org/10.1016/j.jocn.2021.10.020
Heslin ME, Thon JM, Caruso E, Romiyo P, Rana A, Yu S, Thau L, Rana A, Kamen S, Siegler JE. Utility of transesophageal echocardiography in the identification and treatment of occult mechanisms of cerebral infarction. J Clin Neurosci. 2021 Dec 03;95:31-37. doi: 10.1016/j.jocn.2021.10.020. Epub 2021 Dec 03. PMID: 34929648.
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Structural and mutational analysis of member-specific STAT functions.

Biochimica et biophysica acta. General subjects

Erdogan F, Qadree AK, Radu TB, Orlova A, de Araujo ED, Israelian J, Valent P, Mustjoki SM, Herling M, Moriggl R, Gunning PT.
PMID: 34774983
Biochim Biophys Acta Gen Subj. 2021 Nov 11;1866(3):130058. doi: 10.1016/j.bbagen.2021.130058. Epub 2021 Nov 11.

BACKGROUND: The STAT family of transcription factors control gene expression in response to signals from various stimulus. They display functions in diseases ranging from autoimmunity and chronic inflammatory disease to cancer and infectious disease.SCOPE OF REVIEW: This work uses...

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Erdogan F, Qadree AK, Radu TB, et al. Structural and mutational analysis of member-specific STAT functions. Biochim Biophys Acta Gen Subj. 2021;1866(3):130058doi: 10.1016/j.bbagen.2021.130058.
Erdogan, F., Qadree, A. K., Radu, T. B., Orlova, A., de Araujo, E. D., Israelian, J., Valent, P., Mustjoki, S. M., Herling, M., Moriggl, R., & Gunning, P. T. (2021). Structural and mutational analysis of member-specific STAT functions. Biochimica et biophysica acta. General subjects, 1866(3), 130058. https://doi.org/10.1016/j.bbagen.2021.130058
Erdogan, Fettah, et al. "Structural and mutational analysis of member-specific STAT functions." Biochimica et biophysica acta. General subjects vol. 1866,3 (2021): 130058. doi: https://doi.org/10.1016/j.bbagen.2021.130058
Erdogan F, Qadree AK, Radu TB, Orlova A, de Araujo ED, Israelian J, Valent P, Mustjoki SM, Herling M, Moriggl R, Gunning PT. Structural and mutational analysis of member-specific STAT functions. Biochim Biophys Acta Gen Subj. 2021 Nov 11;1866(3):130058. doi: 10.1016/j.bbagen.2021.130058. Epub 2021 Nov 11. PMID: 34774983.
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[No title available]

Cancers

Andersson EI, Brück O, Braun T, Mannisto S, Saikko L, Lagström S, Ellonen P, Leppä S, Herling M, Kovanen PE, Mustjoki S.
PMID: 32188095
Cancers (Basel). 2020 Mar 16;12(3). doi: 10.3390/cancers12030702.

Peripheral T-cell lymphomas (PTCL) are a heterogeneous, and often aggressive group of non-Hodgkin lymphomas. Recent advances in the molecular and genetic characterization of PTCLs have helped to delineate differences and similarities between the various subtypes, and the JAK/STAT pathway...

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Andersson EI, Brück O, Braun T, et al. . Cancers (Basel). 2020;12(3)doi: 10.3390/cancers12030702.
Andersson, E. I., Brück, O., Braun, T., Mannisto, S., Saikko, L., Lagström, S., Ellonen, P., Leppä, S., Herling, M., Kovanen, P. E., & Mustjoki, S. (2020). . Cancers, 12(3), . https://doi.org/10.3390/cancers12030702
Andersson, Emma I, et al. "." Cancers vol. 12,3 (2020). doi: https://doi.org/10.3390/cancers12030702
Andersson EI, Brück O, Braun T, Mannisto S, Saikko L, Lagström S, Ellonen P, Leppä S, Herling M, Kovanen PE, Mustjoki S. . Cancers (Basel). 2020 Mar 16;12(3). doi: 10.3390/cancers12030702. PMID: 32188095; PMCID: PMC7140109.
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The Diverse Roles of γδ T Cells in Cancer: From Rapid Immunity to Aggressive Lymphoma.

Cancers

Schönefeldt S, Wais T, Herling M, Mustjoki S, Bekiaris V, Moriggl R, Neubauer HA.
PMID: 34944832
Cancers (Basel). 2021 Dec 09;13(24). doi: 10.3390/cancers13246212.

γδ T cells are unique players in shaping immune responses, lying at the intersection between innate and adaptive immunity. Unlike conventional αβ T cells, γδ T cells largely populate non-lymphoid peripheral tissues, demonstrating tissue specificity, and they respond to...

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Schönefeldt S, Wais T, Herling M, et al. The Diverse Roles of γδ T Cells in Cancer: From Rapid Immunity to Aggressive Lymphoma. Cancers (Basel). 2021;13(24)doi: 10.3390/cancers13246212.
Schönefeldt, S., Wais, T., Herling, M., Mustjoki, S., Bekiaris, V., Moriggl, R., & Neubauer, H. A. (2021). The Diverse Roles of γδ T Cells in Cancer: From Rapid Immunity to Aggressive Lymphoma. Cancers, 13(24), . https://doi.org/10.3390/cancers13246212
Schönefeldt, Susann, et al. "The Diverse Roles of γδ T Cells in Cancer: From Rapid Immunity to Aggressive Lymphoma." Cancers vol. 13,24 (2021). doi: https://doi.org/10.3390/cancers13246212
Schönefeldt S, Wais T, Herling M, Mustjoki S, Bekiaris V, Moriggl R, Neubauer HA. The Diverse Roles of γδ T Cells in Cancer: From Rapid Immunity to Aggressive Lymphoma. Cancers (Basel). 2021 Dec 09;13(24). doi: 10.3390/cancers13246212. PMID: 34944832.
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The Modes of Dysregulation of the Proto-Oncogene T-Cell Leukemia/Lymphoma 1A.

Cancers

Stachelscheid J, Jiang Q, Herling M.
PMID: 34771618
Cancers (Basel). 2021 Oct 29;13(21). doi: 10.3390/cancers13215455.

Incomplete biological concepts in lymphoid neoplasms still dictate to a large extent the limited availability of efficient targeted treatments, which entertains the mostly unsatisfactory clinical outcomes. Aberrant expression of the embryonal and lymphatic TCL1 family of oncogenes, i.e., the...

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Stachelscheid J, Jiang Q, Herling M. The Modes of Dysregulation of the Proto-Oncogene T-Cell Leukemia/Lymphoma 1A. Cancers (Basel). 2021;13(21)doi: 10.3390/cancers13215455.
Stachelscheid, J., Jiang, Q., & Herling, M. (2021). The Modes of Dysregulation of the Proto-Oncogene T-Cell Leukemia/Lymphoma 1A. Cancers, 13(21), . https://doi.org/10.3390/cancers13215455
Stachelscheid, Johanna, et al. "The Modes of Dysregulation of the Proto-Oncogene T-Cell Leukemia/Lymphoma 1A." Cancers vol. 13,21 (2021). doi: https://doi.org/10.3390/cancers13215455
Stachelscheid J, Jiang Q, Herling M. The Modes of Dysregulation of the Proto-Oncogene T-Cell Leukemia/Lymphoma 1A. Cancers (Basel). 2021 Oct 29;13(21). doi: 10.3390/cancers13215455. PMID: 34771618; PMCID: PMC8582492.
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Showing 1 to 12 of 116 entries