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Showing 1 to 12 of 14 entries
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Application of vinylogous carbamates and vinylogous aminonitriles to the regiospecific synthesis of uniquely functionalized pyrroles and quinolones.

Tetrahedron

Gupton JT, Crawford E, Mahoney M, Clark E, Curry W, Lane A, Shimozono A, Moore-Stoll V, Elofson K, Juekun W, Newton M, Yeudall S, Jaekle E, Kanters R, Sikorski JA.
PMID: 31289413
Tetrahedron. 2018 Dec 27;74(52):7408-7420. doi: 10.1016/j.tet.2018.10.078. Epub 2018 Nov 05.

Pyrroles and quinolones represent core structures, which are routinely found in both natural and synthetic bioactive substances. Consequently, the development of efficient and regiospecific methods for the preparation of such heterocycles with unique functionality is of some importance. We...

Prevention and treatment of trismus in head and neck cancer: A case report and a systematic review of the literature.

Scandinavian journal of pain

Wranicz P, Herlofson BB, Evensen JF, Kongsgaard UE.
PMID: 29913945
Scand J Pain. 2010 Apr 01;1(2):84-88. doi: 10.1016/j.sjpain.2010.01.006.

Introduction Trismus, or limited mouth opening, is a well-known complication of head and neck cancer and its treatment. It may be caused by tumour infiltration into the masticatory muscles or by treatment like surgery and radiotherapy. A limited mouth...

Ipilimumab in a real-world population: A prospective Phase IV trial with long-term follow-up.

International journal of cancer

Aamdal E, Jacobsen KD, Straume O, Kersten C, Herlofsen O, Karlsen J, Hussain I, Amundsen A, Dalhaug A, Nyakas M, Schuster C, Hagene KT, Holmsen K, Russnes HG, Skovlund E, Kaasa S, Aamdal S, Kyte JA, Guren TK.
PMID: 34449877
Int J Cancer. 2022 Jan 01;150(1):100-111. doi: 10.1002/ijc.33768. Epub 2021 Sep 09.

Ipilimumab was the first treatment that improved survival in advanced melanoma. Efficacy and toxicity in a real-world setting may differ from clinical trials, due to more liberal eligibility criteria and less intensive monitoring. Moreover, high costs and lack of...

Alendronate and omeprazole in combination reduce angiogenic and growth signals from osteoblasts.

Bone reports

Krüger TB, Herlofson BB, Lian AM, Syversen U, Reseland JE.
PMID: 33553512
Bone Rep. 2021 Jan 26;14:100750. doi: 10.1016/j.bonr.2021.100750. eCollection 2021 Jun.

OBJECTIVE: Due to gastrointestinal side effects of oral bisphosphonates (BPs), proton pump inhibitors (PPIs) are often prescribed. PPIs may enhance the risk of osteonecrosis of the jaw, a rare side effect of BPs. Therefore, the objective of this study...

Alterations in meibomian glands in patients treated with intensity-modulated radiotherapy for head and neck cancer.

Scientific reports

Chen X, Badian RA, Hynne H, Amdal CD, Herlofson BB, Utheim ØA, Westgaard KL, Fineide F, Jensen JL, Utheim TP.
PMID: 34789830
Sci Rep. 2021 Nov 17;11(1):22419. doi: 10.1038/s41598-021-01844-9.

Patients undergoing intensity-modulated radiotherapy (IMRT) for head and neck cancer may have increased incidence of dry eye disease and the exact mechanism is unclear. The present study aims to assess tear film and meibomian gland (MG) features in patients...

Fatigue in Parkinson's disease: report from a mutidisciplinary symposium.

NPJ Parkinson's disease

Friedman JH, Beck JC, Chou KL, Clark G, Fagundes CP, Goetz CG, Herlofson K, Kluger B, Krupp LB, Lang AE, Lou JS, Marsh L, Newbould A, Weintraub D.
PMID: 27239558
NPJ Parkinsons Dis. 2016;2. doi: 10.1038/npjparkd.2015.25. Epub 2016 Jan 14.

Fatigue is a severe problem for many people living with Parkinson's disease (PD). Best estimates suggest that more than 50% of patients experience this debilitating symptom. Little is known about its etiology or treatment, making the understanding of fatigue...

Associations between paid and unpaid work among Norwegian seniors: competition, complementarity or continuity?.

European journal of ageing

Vangen H, Hellevik T, Herlofson K.
PMID: 34786010
Eur J Ageing. 2021 Mar 22;18(4):479-489. doi: 10.1007/s10433-021-00615-9. eCollection 2021 Dec.

A key issue in policy debates on active ageing is how to increase older people's participation in both paid and unpaid work. This combined goal raises the question of whether the different activities compete for seniors' time and energy...

Methodological approach for determining the Minimal Important Difference and Minimal Important Change scores for the European Organisation for Research and Treatment of Cancer Head and Neck Cancer Module (EORTC QLQ-HN43) exemplified by the Swallowing scale.

Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation

Singer S, Hammerlid E, Tomaszewska IM, Amdal CD, Bjordal K, Herlofson BB, Santos M, Silva JC, Mehanna H, Fullerton A, Brannan C, Gonzalez LF, Inhestern J, Pinto M, Arraras JI, Yarom N, Bonomo P, Baumann I, Galalae R, Nicolatou-Galitis O, Kiyota N, Raber-Durlacher J, Salem D, Fabian A, Boehm A, Krejovic-Trivic S, Chie WC, Taylor K, Simon C, Licitra L, Sherman AC.
PMID: 34272632
Qual Life Res. 2021 Jul 16; doi: 10.1007/s11136-021-02939-6. Epub 2021 Jul 16.

PURPOSE: The aim of this study was to explore what methods should be used to determine the minimal important difference (MID) and minimal important change (MIC) in scores for the European Organisation for Research and Treatment of Cancer Head...

Oral and ocular late effects in head and neck cancer patients treated with radiotherapy.

Scientific reports

Westgaard KL, Hynne H, Amdal CD, Young A, Singh PB, Chen X, Rykke M, Hove LH, Aqrawi LA, Utheim TP, Herlofson BB, Jensen JL.
PMID: 33597629
Sci Rep. 2021 Feb 17;11(1):4026. doi: 10.1038/s41598-021-83635-w.

A broader understanding of oral and ocular late effects in head and neck cancer (HNC) patients who underwent intensity-modulated radiotherapy (IMRT) may provide valuable information in follow-up and improve quality of life. Twenty-nine HNC patients treated at least 6...

Design and methods for a Scandinavian pharmacovigilance study of osteonecrosis of the jaw and serious infections among cancer patients treated with antiresorptive agents for the prevention of skeletal-related events.

Clinical epidemiology

Acquavella J, Ehrenstein V, Schiødt M, Heide-Jørgensen U, Kjellman A, Hansen S, Larsson Wexell C, Herlofson BB, Noerholt SE, Ma H, Öhrling K, Hernandez RK, Sørensen HT.
PMID: 27499646
Clin Epidemiol. 2016 Jul 20;8:267-72. doi: 10.2147/CLEP.S107270. eCollection 2016.

OBJECTIVE: Osteonecrosis of the jaw (ONJ) is a recognized complication of potent antiresorptive therapies, especially at the doses indicated to prevent skeletal complications for cancer patients with bone metastases. This paper describes the rationale and methods for a prospective,...

Existing data sources for clinical epidemiology: Scandinavian Cohort for osteonecrosis of the jaw - work in progress and challenges.

Clinical epidemiology

Schiodt M, Larsson Wexell C, Herlofson BB, Giltvedt KM, Norholt SE, Ehrenstein V.
PMID: 25657594
Clin Epidemiol. 2015 Jan 30;7:107-16. doi: 10.2147/CLEP.S71796. eCollection 2015.

Osteonecrosis of the jaw (ONJ) is a severe side effect associated with antiresorptive treatment. Monitoring of ONJ using routine databases in Scandinavian countries is a challenge owing to lack of valid algorithms and to heterogeneous referral practices. The aim...

Alterations in meibomian glands in patients treated with intensity-modulated radiotherapy for head and neck cancer.

Scientific reports

Chen X, Badian RA, Hynne H, Amdal CD, Herlofson BB, Utheim ØA, Westgaard KL, Fineide F, Jensen JL, Utheim TP.
PMID: 34789830
Sci Rep. 2021 Nov 17;11(1):22419. doi: 10.1038/s41598-021-01844-9.

Patients undergoing intensity-modulated radiotherapy (IMRT) for head and neck cancer may have increased incidence of dry eye disease and the exact mechanism is unclear. The present study aims to assess tear film and meibomian gland (MG) features in patients...

Showing 1 to 12 of 14 entries