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Showing 1 to 12 of 34 entries
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The Rac1 regulator ELMO controls basal body migration and docking in multiciliated cells through interaction with Ezrin.

Development (Cambridge, England)

Epting D, Slanchev K, Boehlke C, Hoff S, Loges NT, Yasunaga T, Indorf L, Nestel S, Lienkamp SS, Omran H, Kuehn EW, Ronneberger O, Walz G, Kramer-Zucker A.
PMID: 25852201
Development. 2015 Apr 15;142(8):1553. doi: 10.1242/dev.124214.

No abstract available.

The NHGRI-EBI GWAS Catalog of published genome-wide association studies, targeted arrays and summary statistics 2019.

Nucleic acids research

Buniello A, MacArthur JAL, Cerezo M, Harris LW, Hayhurst J, Malangone C, McMahon A, Morales J, Mountjoy E, Sollis E, Suveges D, Vrousgou O, Whetzel PL, Amode R, Guillen JA, Riat HS, Trevanion SJ, Hall P, Junkins H, Flicek P, Burdett T, Hindorff LA, Cunningham F, Parkinson H.
PMID: 30445434
Nucleic Acids Res. 2019 Jan 08;47:D1005-D1012. doi: 10.1093/nar/gky1120.

The GWAS Catalog delivers a high-quality curated collection of all published genome-wide association studies enabling investigations to identify causal variants, understand disease mechanisms, and establish targets for novel therapies. The scope of the Catalog has also expanded to targeted...

Characterisation offusarium graminearum andF. culmorum isolates by mycotoxin production and aggressiveness to wheat.

Mycotoxin research

Muthomi J, Dehne H, Oerke E, Mutitu E, Hindorf H.
PMID: 23605414
Mycotoxin Res. 2000 Mar;16:50-3. doi: 10.1007/BF02942980.

A total of 27Fusarium culmorum isolates from Germany and 41F. graminearum isolates from Kenya were investigated for aggressiveness and mycotoxin production on wheat ears. In addition, ergosterol content of the kernels from ears inoculated withF. graminearum was determined and...

Indomethacin prevents the increase in urea synthesis capacity and the weight loss after hysterectomy in rats.

Clinical nutrition (Edinburgh, Scotland)

Heindorff H, Almdal T, Vilstrup H.
PMID: 16837340
Clin Nutr. 1990 Apr;9(2):103-7. doi: 10.1016/0261-5614(90)90061-v.

Prostaglandins have been suggested to be mediators of post-operative catabolism. Previous studies have shown that stimulation of urea synthesis contributes to post-operative nitrogen loss. The effect of prostaglandins on this hepatic function was assessed in hysterectomized rats on the...

Clinical Sequencing Exploratory Research Consortium: Accelerating Evidence-Based Practice of Genomic Medicine.

American journal of human genetics

Green RC, Goddard KA, Jarvik GP, Amendola LM, Appelbaum PS, Berg JS, Bernhardt BA, Biesecker LG, Biswas S, Blout CL, Bowling KM, Brothers KB, Burke W, Caga-Anan CF, Chinnaiyan AM, Chung WK, Clayton EW, Cooper GM, East K, Evans JP, Fullerton SM, Garraway LA, Garrett JR, Gray SW, Henderson GE, Hindorff LA, Holm IA, Lewis MH, Hutter CM, Janne PA, Joffe S, Kaufman D, Knoppers BM, Koenig BA, Krantz ID, Manolio TA, McCullough L, McEwen J, McGuire A, Muzny D, Myers RM, Nickerson DA, Ou J, Parsons DW, Petersen GM, Plon SE, Rehm HL, Roberts JS, Robinson D, Salama JS, Scollon S, Sharp RR, Shirts B, Spinner NB, Tabor HK, Tarczy-Hornoch P, Veenstra DL, Wagle N, Weck K, Wilfond BS, Wilhelmsen K, Wolf SM, Wynn J, Yu JH.
PMID: 27392080
Am J Hum Genet. 2016 Jul 07;99(1):246. doi: 10.1016/j.ajhg.2016.06.002.

No abstract available.

Generalization and fine mapping of red blood cell trait genetic associations to multi-ethnic populations: The PAGE Study.

American journal of hematology

Jo Hodonsky C, Schurmann C, Schick UM, Kocarnik J, Tao R, van Rooij FJ, Wassel C, Buyske S, Fornage M, Hindorff LA, Floyd JS, Ganesh SK, Lin DY, North KE, Reiner AP, Loos RJ, Kooperberg C, Avery CL.
PMID: 29905378
Am J Hematol. 2018 Jun 15; doi: 10.1002/ajh.25161. Epub 2018 Jun 15.

Red blood cell (RBC) traits provide insight into a wide range of physiological states and exhibit moderate to high heritability, making them excellent candidates for genetic studies to inform underlying biologic mechanisms. Previous RBC trait genome-wide association studies were...

Cancer biotherapy & radiopharmaceuticals

Lindén O, Bates AT, Cunningham D, Hindorf C, Larsson E, Cleton A, Pinkert J, Huang F, Bladt F, Hennekes H, Oedegaardstuen LI, Sturm I, McNamara C.
PMID: 33887152
Cancer Biother Radiopharm. 2021 Oct;36(8):672-681. doi: 10.1089/cbr.2020.4653. Epub 2021 Apr 21.

No abstract available.

Examining access to care in clinical genomic research and medicine: Experiences from the CSER Consortium.

Journal of clinical and translational science

Gutierrez AM, Robinson JO, Outram SM, Smith HS, Kraft SA, Donohue KE, Biesecker BB, Brothers KB, Chen F, Hailu B, Hindorff LA, Hoban H, Hsu RL, Knight SJ, Koenig BA, Lewis KL, Lich KH, O'Daniel JM, Okuyama S, Tomlinson GE, Waltz M, Wilfond BS, Ackerman SL, Majumder MA.
PMID: 34888063
J Clin Transl Sci. 2021 Sep 14;5(1):e193. doi: 10.1017/cts.2021.855. eCollection 2021.

INTRODUCTION: Ensuring equitable access to health care is a widely agreed-upon goal in medicine, yet access to care is a multidimensional concept that is difficult to measure. Although frameworks exist to evaluate access to care generally, the concept of...

US private payers' perspectives on insurance coverage for genome sequencing versus exome sequencing: A study by the Clinical Sequencing Evidence-Generating Research Consortium (CSER).

Genetics in medicine : official journal of the American College of Medical Genetics

Phillips KA, Trosman JR, Douglas MP, Gelb BD, Ferket BS, Hindorff LA, Slavotinek AM, Berg JS, Russell HV, Devine B, Greve V, Smith HS.
PMID: 34906461
Genet Med. 2022 Jan;24(1):238-244. doi: 10.1016/j.gim.2021.08.009. Epub 2021 Nov 30.

PURPOSE: There is limited payer coverage for genome sequencing (GS) relative to exome sequencing (ES) in the U.S. Our objective was to assess payers' considerations for coverage of GS versus coverage of ES and requirements payers have for coverage...

Sequencing-based genome-wide association studies reporting standards.

Cell genomics

McMahon A, Lewis E, Buniello A, Cerezo M, Hall P, Sollis E, Parkinson H, Hindorff LA, Harris LW, MacArthur JAL.
PMID: 34870259
Cell Genom. 2021 Oct 13;1(1). doi: 10.1016/j.xgen.2021.100005.

Genome sequencing has recently become a viable genotyping technology for use in genome-wide association studies (GWASs), offering the potential to analyze a broader range of genome-wide variation, including rare variants. To survey current standards, we assessed the content and...

Effects of hysterectomy and semi-starvation on amino-acid gradients across liver, muscle and gut in rats.

Clinical nutrition (Edinburgh, Scotland)

Heindorff H, Almdal T, Vilstrup H.
PMID: 16837367
Clin Nutr. 1990 Oct;9(5):253-9. doi: 10.1016/0261-5614(90)90033-o.

To study the effects of surgical stress and insufficient food intake on amino-acid exchange of liver, gut, and muscle, blood was sampled in random sequence from the aorta, the inferior caval vein, the portal vein, and the hepatic veins...

Calculation of optical-waveguide grating characteristics using Green's functions and Dyson's equation.

Physical review. E, Statistical, nonlinear, and soft matter physics

Rindorf L, Mortensen NA.
PMID: 17025773
Phys Rev E Stat Nonlin Soft Matter Phys. 2006 Sep;74(3):036616. doi: 10.1103/PhysRevE.74.036616. Epub 2006 Sep 18.

We present a method for calculating the transmission spectra, dispersion, and time delay characteristics of optical-waveguide gratings based on Green's functions and Dyson's equation. Starting from the wave equation for transverse electric modes we show that the method can...

Showing 1 to 12 of 34 entries