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Showing 1 to 10 of 10 entries
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High-energy collision-induced dissociation mass spectrometry of synthetic mannose-6-phosphate oligosaccharides.

Journal of the American Society for Mass Spectrometry

Lipniunas PH, Townsend RR, Burlingame AL, Hindsgaul O.
PMID: 24203240
J Am Soc Mass Spectrom. 1996 Feb;7(2):182-8. doi: 10.1016/1044-0305(95)00635-4.

The high-energy collision-induced dissociation spectra of a series of linear and branched synthetic mannosyl oligosaccharides that contain 6-phosphate substituents on either or both non-reducing terminal or penultimate residues have been studied. These phosphorylated structures were designed to mimic those...

A fluorescence assay that detects long branches in the starch polysaccharide amylopectin.

Chemical communications (Cambridge, England)

Beeren SR, Hindsgaul O.
PMID: 24419478
Chem Commun (Camb). 2014 Feb 14;50(13):1530-2. doi: 10.1039/c3cc48163h.

Long α(1-4)-linked glucopyranose branches in the starch polysaccharide amylopectin can be detected by the specific binding of an anionic amphiphilic fluorescent probe. The probe forms spermidine-stabilised micelles in water resulting in fluorescence quenching. By extracting the probe from the...

Biopolymers .

Current opinion in chemical biology

Hecht MH, Hindsgaul O, Kool ET.
PMID: 9914197
Curr Opin Chem Biol. 1998 Dec;2(6):673-4. doi: 10.1016/s1367-5931(98)80101-4.

No abstract available.

Raymond Urgel Lemieux (June 16, 1920-July 22, 2000): A Lifelong Love Affair with Sugar Chemistry.

The Journal of organic chemistry

Hindsgaul O.
PMID: 33334106
J Org Chem. 2020 Dec 18;85(24):15773-15777. doi: 10.1021/acs.joc.0c02255.

No abstract available.

The 2-N,N-Dibenzylamino Group as a Participating Group in the Synthesis of β-Glycosides.

Angewandte Chemie (International ed. in English)

Jiao H, Hindsgaul O.
PMID: 29711657
Angew Chem Int Ed Engl. 1999 Feb 01;38(3):346-348. doi: 10.1002/(SICI)1521-3773(19990201)38:3<346::AID-ANIE346>3.0.CO;2-L.

The novel glycosyl donor 2-N,N-dibenzylaminothioglycoside 1 reacts with glycopyranoside alcohols 2, presumably via intermediate 3, to provide 1,2-trans-linked disaccharides 4 in high yield (78-86 %) and with high stereoselectivity. The N-benzyl protecting groups are readily cleaved under normal hydrogenolysis...

Versatile Functionalization of Carbohydrate Hydroxyl Groups through Their O-Cyanomethyl Ethers.

The Journal of organic chemistry

Malet C, Hindsgaul O.
PMID: 11667393
J Org Chem. 1996 Jul 12;61(14):4649-4654. doi: 10.1021/jo960284z.

O-Cyanomethyl ethers of carbohydrates are shown to be versatile intermediates for the preparation of sugar amines, carboxylic acids, amides, and amidine salts. This methodology for the functionalization of carbohydrates can thus provide a new array of analogs for the...

Synthesis of 1,2-phenylenediamine capturing molecule for the detection of diacetyl.

Data in brief

Marri L, Jansson AM, Christensen CE, Hindsgaul O.
PMID: 29062874
Data Brief. 2017 Oct 06;15:483-490. doi: 10.1016/j.dib.2017.09.072. eCollection 2017 Dec.

Here we describe the design of 1,2-phenylenediamine capturing molecule and the synthesis steps necessary for its preparation. The designed 1,2-phenylenediamine derivative is able to capture diacetyl in solution, as shown by ESIMS, forming a chemical adduct, 1-4-quinoxaline. The methyl...

Solid-Phase Synthesis of Thio-oligosaccharides.

Angewandte Chemie (International ed. in English)

Hummel G, Hindsgaul O.
PMID: 29711181
Angew Chem Int Ed Engl. 1999 Jun 14;38(12):1782-1784. doi: 10.1002/(SICI)1521-3773(19990614)38:12<1782::AID-ANIE1782>3.0.CO;2-1.

No protecting groups are present in the highly reactive polymer-bound sugar 1-thiolates 1, which undergo reactions with sugar triflates 2 to give thio-oligosaccharides 3 in high yield. Tr=trityl=triphenylmethyl, Tf=trifluoromethylsulfonyl, Bz=benzoyl.

SUPPLEMENTARY MATERIAL: crystal state and solution conformation of the B blood group trisaccharide alpha-l-fucp-(1-->2)-.

European journal of biochemistry

Ball RG, Bundle DR, Hindsgaul O, Lemieux RU, Otter A, Venot AP.
PMID: 9914540
Eur J Biochem. 1999 Jan;259(1):E1.
Free Article

No abstract available.

Micro-Scale Frontal Affinity Chromatography with Mass Spectrometric Detection: A New Method for the Screening of Compound Libraries.

Angewandte Chemie (International ed. in English)

Schriemer DC, Bundle DR, Li L, Hindsgaul O.
PMID: 29711300
Angew Chem Int Ed Engl. 1998 Dec 31;37(24):3383-3387. doi: 10.1002/(SICI)1521-3773(19981231)37:24<3383::AID-ANIE3383>3.0.CO;2-C.

In one run the binding constants K

Showing 1 to 10 of 10 entries