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Showing 1 to 12 of 17 entries
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Adjuvants for plasmid DNA vaccines.

Methods in molecular medicine

Norman J, Hartikka J, Strauch P, Manthorpe M.
PMID: 21374320
Methods Mol Med. 2000;29:185-96. doi: 10.1385/1-59259-688-6:185.

In the late 1980s, Jon Wolff of the University of Wisconsin and Phil Felgner here at Vical were screening cationic lipids for their ability to encapsulate and deliver purified plasmid DNA into mouse tissues. They discovered that direct injection...

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Norman J, Hartikka J, Strauch P, et al. Adjuvants for plasmid DNA vaccines. Methods Mol Med. 2000;29:185-96doi: 10.1385/1-59259-688-6:185.
Norman, J., Hartikka, J., Strauch, P., & Manthorpe, M. (2000). Adjuvants for plasmid DNA vaccines. Methods in molecular medicine, 29185-96. https://doi.org/10.1385/1-59259-688-6:185
Norman, J, et al. "Adjuvants for plasmid DNA vaccines." Methods in molecular medicine vol. 29 (2000): 185-96. doi: https://doi.org/10.1385/1-59259-688-6:185
Norman J, Hartikka J, Strauch P, Manthorpe M. Adjuvants for plasmid DNA vaccines. Methods Mol Med. 2000;29:185-96. doi: 10.1385/1-59259-688-6:185. PMID: 21374320.
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The Patients' Practises Disclosing Subjective Experiences in the Psychiatric Intake Interview.

Frontiers in psychiatry

Savander EÈ, Hintikka J, Wuolio M, Peräkylä A.
PMID: 34040547
Front Psychiatry. 2021 May 10;12:605760. doi: 10.3389/fpsyt.2021.605760. eCollection 2021.

In psychiatric diagnostic interviews, a clinician's question designed to elicit a specific symptom description is sometimes met with the patient's self-disclosure of their subjective experience. In shifting the topical focus to their subjective experiences, the patients do something more...

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Savander EÈ, Hintikka J, Wuolio M, et al. The Patients' Practises Disclosing Subjective Experiences in the Psychiatric Intake Interview. Front Psychiatry. 2021;12:605760doi: 10.3389/fpsyt.2021.605760.
Savander, E. �. �., Hintikka, J., Wuolio, M., & Peräkylä, A. (2021). The Patients' Practises Disclosing Subjective Experiences in the Psychiatric Intake Interview. Frontiers in psychiatry, 12605760. https://doi.org/10.3389/fpsyt.2021.605760
Savander, Enikö Èva, et al. "The Patients' Practises Disclosing Subjective Experiences in the Psychiatric Intake Interview." Frontiers in psychiatry vol. 12 (2021): 605760. doi: https://doi.org/10.3389/fpsyt.2021.605760
Savander EÈ, Hintikka J, Wuolio M, Peräkylä A. The Patients' Practises Disclosing Subjective Experiences in the Psychiatric Intake Interview. Front Psychiatry. 2021 May 10;12:605760. doi: 10.3389/fpsyt.2021.605760. eCollection 2021. PMID: 34040547; PMCID: PMC8141629.
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Social support may prevent self-cutting in adolescence: A 5-year follow-up study.

Journal of child and adolescent psychiatric nursing : official publication of the Association of Child and Adolescent Psychiatric Nurses, Inc

Rissanen ML, Kekkonen V, Kraav SL, Kivimäki P, Laukkanen E, Hintikka J, Tolmunen T.
PMID: 34164876
J Child Adolesc Psychiatr Nurs. 2021 Nov;34(4):343-351. doi: 10.1111/jcap.12341. Epub 2021 Jun 24.

Self-cutting is common among adolescents. However, studies examining protective factors are rare. It has been suggested that social support may protect against self-cutting in adolescence. The aim of this study was to investigate the possible association of social relationships...

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Rissanen ML, Kekkonen V, Kraav SL, et al. Social support may prevent self-cutting in adolescence: A 5-year follow-up study. J Child Adolesc Psychiatr Nurs. 2021;34(4):343-351doi: 10.1111/jcap.12341.
Rissanen, M. L., Kekkonen, V., Kraav, S. L., Kivimäki, P., Laukkanen, E., Hintikka, J., & Tolmunen, T. (2021). Social support may prevent self-cutting in adolescence: A 5-year follow-up study. Journal of child and adolescent psychiatric nursing : official publication of the Association of Child and Adolescent Psychiatric Nurses, Inc, 34(4), 343-351. https://doi.org/10.1111/jcap.12341
Rissanen, Marja-Liisa, et al. "Social support may prevent self-cutting in adolescence: A 5-year follow-up study." Journal of child and adolescent psychiatric nursing : official publication of the Association of Child and Adolescent Psychiatric Nurses, Inc vol. 34,4 (2021): 343-351. doi: https://doi.org/10.1111/jcap.12341
Rissanen ML, Kekkonen V, Kraav SL, Kivimäki P, Laukkanen E, Hintikka J, Tolmunen T. Social support may prevent self-cutting in adolescence: A 5-year follow-up study. J Child Adolesc Psychiatr Nurs. 2021 Nov;34(4):343-351. doi: 10.1111/jcap.12341. Epub 2021 Jun 24. PMID: 34164876.
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Highly ductile amorphous oxide at room temperature and high strain rate.

Science (New York, N.Y.)

Frankberg EJ, Kalikka J, García Ferré F, Joly-Pottuz L, Salminen T, Hintikka J, Hokka M, Koneti S, Douillard T, Le Saint B, Kreiml P, Cordill MJ, Epicier T, Stauffer D, Vanazzi M, Roiban L, Akola J, Di Fonzo F, Levänen E, Masenelli-Varlot K.
PMID: 31727833
Science. 2019 Nov 15;366(6467):864-869. doi: 10.1126/science.aav1254.

Oxide glasses are an integral part of the modern world, but their usefulness can be limited by their characteristic brittleness at room temperature. We show that amorphous aluminum oxide can permanently deform without fracture at room temperature and high...

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Frankberg EJ, Kalikka J, García Ferré F, et al. Highly ductile amorphous oxide at room temperature and high strain rate. Science. 2019;366(6467):864-869doi: 10.1126/science.aav1254.
Frankberg, E. J., Kalikka, J., García Ferré, F., Joly-Pottuz, L., Salminen, T., Hintikka, J., Hokka, M., Koneti, S., Douillard, T., Le Saint, B., Kreiml, P., Cordill, M. J., Epicier, T., Stauffer, D., Vanazzi, M., Roiban, L., Akola, J., Di Fonzo, F., Levänen, E., & Masenelli-Varlot, K. (2019). Highly ductile amorphous oxide at room temperature and high strain rate. Science (New York, N.Y.), 366(6467), 864-869. https://doi.org/10.1126/science.aav1254
Frankberg, Erkka J, et al. "Highly ductile amorphous oxide at room temperature and high strain rate." Science (New York, N.Y.) vol. 366,6467 (2019): 864-869. doi: https://doi.org/10.1126/science.aav1254
Frankberg EJ, Kalikka J, García Ferré F, Joly-Pottuz L, Salminen T, Hintikka J, Hokka M, Koneti S, Douillard T, Le Saint B, Kreiml P, Cordill MJ, Epicier T, Stauffer D, Vanazzi M, Roiban L, Akola J, Di Fonzo F, Levänen E, Masenelli-Varlot K. Highly ductile amorphous oxide at room temperature and high strain rate. Science. 2019 Nov 15;366(6467):864-869. doi: 10.1126/science.aav1254. PMID: 31727833.
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Tianeptine induces expression of dual specificity phosphatases and evokes rebound emergence of cortical slow wave electrophysiological activity.

Neuroscience letters

Rozov SV, Rosenholm M, Hintikka S, Rantamäki T.
PMID: 34464676
Neurosci Lett. 2021 Nov 01;764:136200. doi: 10.1016/j.neulet.2021.136200. Epub 2021 Aug 28.

BACKGROUND: The precise mechanism governing the antidepressant effects of tianeptine is unknown. Modulation of brain glutamatergic neurotransmission has been however implicated, suggesting potential shared features with rapid-acting antidepressants targeting N-methyl-D-aspartate receptors (NMDAR). Our recent studies suggest that a single...

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Rozov SV, Rosenholm M, Hintikka S, et al. Tianeptine induces expression of dual specificity phosphatases and evokes rebound emergence of cortical slow wave electrophysiological activity. Neurosci Lett. 2021;764:136200doi: 10.1016/j.neulet.2021.136200.
Rozov, S. V., Rosenholm, M., Hintikka, S., & Rantamäki, T. (2021). Tianeptine induces expression of dual specificity phosphatases and evokes rebound emergence of cortical slow wave electrophysiological activity. Neuroscience letters, 764136200. https://doi.org/10.1016/j.neulet.2021.136200
Rozov, Stanislav V, et al. "Tianeptine induces expression of dual specificity phosphatases and evokes rebound emergence of cortical slow wave electrophysiological activity." Neuroscience letters vol. 764 (2021): 136200. doi: https://doi.org/10.1016/j.neulet.2021.136200
Rozov SV, Rosenholm M, Hintikka S, Rantamäki T. Tianeptine induces expression of dual specificity phosphatases and evokes rebound emergence of cortical slow wave electrophysiological activity. Neurosci Lett. 2021 Nov 01;764:136200. doi: 10.1016/j.neulet.2021.136200. Epub 2021 Aug 28. PMID: 34464676.
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Occurrence of Trichothecenes in feed and cereals in Finland.

Mycotoxin research

Hintikka EL, Saari L, Berg S, Rizzo A, Karppanen E.
PMID: 23605013
Mycotoxin Res. 1987 Mar;3:28-31. doi: 10.1007/BF03192021.

In 1985 82 samples of feed and food grain were analyzed for trichothecenes deoxynivalenol (DON), nivalenol (NV), diacetoxyscirpenol (DAS), T-2 toxin, HT-2 toxin and fusarenon-X (F-X). Trichothecenes were found in 77 of these samples. The highest amounts were DON...

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Hintikka EL, Saari L, Berg S, et al. Occurrence of Trichothecenes in feed and cereals in Finland. Mycotoxin Res. 1987;3:28-31doi: 10.1007/BF03192021.
Hintikka, E. L., Saari, L., Berg, S., Rizzo, A., & Karppanen, E. (1987). Occurrence of Trichothecenes in feed and cereals in Finland. Mycotoxin research, 328-31. https://doi.org/10.1007/BF03192021
Hintikka, E L, et al. "Occurrence of Trichothecenes in feed and cereals in Finland." Mycotoxin research vol. 3 (1987): 28-31. doi: https://doi.org/10.1007/BF03192021
Hintikka EL, Saari L, Berg S, Rizzo A, Karppanen E. Occurrence of Trichothecenes in feed and cereals in Finland. Mycotoxin Res. 1987 Mar;3:28-31. doi: 10.1007/BF03192021. PMID: 23605013.
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Tianeptine induces expression of dual specificity phosphatases and evokes rebound emergence of cortical slow wave electrophysiological activity.

Neuroscience letters

Rozov SV, Rosenholm M, Hintikka S, Rantamäki T.
PMID: 34464676
Neurosci Lett. 2021 Nov 01;764:136200. doi: 10.1016/j.neulet.2021.136200. Epub 2021 Aug 28.

BACKGROUND: The precise mechanism governing the antidepressant effects of tianeptine is unknown. Modulation of brain glutamatergic neurotransmission has been however implicated, suggesting potential shared features with rapid-acting antidepressants targeting N-methyl-D-aspartate receptors (NMDAR). Our recent studies suggest that a single...

Cite
Rozov SV, Rosenholm M, Hintikka S, et al. Tianeptine induces expression of dual specificity phosphatases and evokes rebound emergence of cortical slow wave electrophysiological activity. Neurosci Lett. 2021;764:136200doi: 10.1016/j.neulet.2021.136200.
Rozov, S. V., Rosenholm, M., Hintikka, S., & Rantamäki, T. (2021). Tianeptine induces expression of dual specificity phosphatases and evokes rebound emergence of cortical slow wave electrophysiological activity. Neuroscience letters, 764136200. https://doi.org/10.1016/j.neulet.2021.136200
Rozov, Stanislav V, et al. "Tianeptine induces expression of dual specificity phosphatases and evokes rebound emergence of cortical slow wave electrophysiological activity." Neuroscience letters vol. 764 (2021): 136200. doi: https://doi.org/10.1016/j.neulet.2021.136200
Rozov SV, Rosenholm M, Hintikka S, Rantamäki T. Tianeptine induces expression of dual specificity phosphatases and evokes rebound emergence of cortical slow wave electrophysiological activity. Neurosci Lett. 2021 Nov 01;764:136200. doi: 10.1016/j.neulet.2021.136200. Epub 2021 Aug 28. PMID: 34464676.
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Increased Serum PAI-1 Levels in Subjects with Metabolic Syndrome and Long-Term Adverse Mental Symptoms: A Population-Based Study.

Cardiovascular psychiatry and neurology

Huotari A, Lehto SM, Niskanen L, Herzig KH, Hintikka J, Koivumaa-Honkanen H, Tolmunen T, Honkalampi K, Kaikkonen N, Viinamäki H.
PMID: 20300596
Cardiovasc Psychiatry Neurol. 2010;2010:501349. doi: 10.1155/2010/501349. Epub 2010 Mar 14.

Depression is an independent risk factor for cardiovascular diseases and is associated with metabolic syndrome (MetS). Levels of plasminogen activator inhibitor-1 (PAI-1), an inhibitor of tissue-type and urokinase-type plasminogen activators, are associated with MetS. To clarify the role of...

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Huotari A, Lehto SM, Niskanen L, et al. Increased Serum PAI-1 Levels in Subjects with Metabolic Syndrome and Long-Term Adverse Mental Symptoms: A Population-Based Study. Cardiovasc Psychiatry Neurol. 2010;2010:501349doi: 10.1155/2010/501349.
Huotari, A., Lehto, S. M., Niskanen, L., Herzig, K. H., Hintikka, J., Koivumaa-Honkanen, H., Tolmunen, T., Honkalampi, K., Kaikkonen, N., & Viinamäki, H. (2010). Increased Serum PAI-1 Levels in Subjects with Metabolic Syndrome and Long-Term Adverse Mental Symptoms: A Population-Based Study. Cardiovascular psychiatry and neurology, 2010501349. https://doi.org/10.1155/2010/501349
Huotari, Anne, et al. "Increased Serum PAI-1 Levels in Subjects with Metabolic Syndrome and Long-Term Adverse Mental Symptoms: A Population-Based Study." Cardiovascular psychiatry and neurology vol. 2010 (2010): 501349. doi: https://doi.org/10.1155/2010/501349
Huotari A, Lehto SM, Niskanen L, Herzig KH, Hintikka J, Koivumaa-Honkanen H, Tolmunen T, Honkalampi K, Kaikkonen N, Viinamäki H. Increased Serum PAI-1 Levels in Subjects with Metabolic Syndrome and Long-Term Adverse Mental Symptoms: A Population-Based Study. Cardiovasc Psychiatry Neurol. 2010;2010:501349. doi: 10.1155/2010/501349. Epub 2010 Mar 14. PMID: 20300596; PMCID: PMC2838223.
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Development and characterization of lyophilized DNA vaccine formulations.

Methods in molecular medicine

Shen NL, Hartikka J, Horn NA, Manthorpe M, Marquet M.
PMID: 21374306
Methods Mol Med. 2000;29:23-34. doi: 10.1385/1-59259-688-6:23.

The potential applications of using plasmid DNA for immunization and other gene therapy approaches have been discussed in an increasing number of publications in the past few years. Injection of mouse muscle with naked DNA (plasmid DNA in saline)...

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Shen NL, Hartikka J, Horn NA, et al. Development and characterization of lyophilized DNA vaccine formulations. Methods Mol Med. 2000;29:23-34doi: 10.1385/1-59259-688-6:23.
Shen, N. L., Hartikka, J., Horn, N. A., Manthorpe, M., & Marquet, M. (2000). Development and characterization of lyophilized DNA vaccine formulations. Methods in molecular medicine, 2923-34. https://doi.org/10.1385/1-59259-688-6:23
Shen, N L, et al. "Development and characterization of lyophilized DNA vaccine formulations." Methods in molecular medicine vol. 29 (2000): 23-34. doi: https://doi.org/10.1385/1-59259-688-6:23
Shen NL, Hartikka J, Horn NA, Manthorpe M, Marquet M. Development and characterization of lyophilized DNA vaccine formulations. Methods Mol Med. 2000;29:23-34. doi: 10.1385/1-59259-688-6:23. PMID: 21374306.
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Corrigendum to "Analysis of anabolic steroids in urine by gas chromatography-microchip atmospheric pressure photoionization-mass spectrometry with chlorobenzene as dopant" [J. Chromatogr. A 1312 (2013) 111-117].

Journal of chromatography. A

Hintikka L, Haapala M, Kuuranne T, Leinonen A, Kostiainen R.
PMID: 27133863
J Chromatogr A. 2016 May 27;1448:128. doi: 10.1016/j.chroma.2016.04.059. Epub 2016 Apr 28.

No abstract available.

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Hintikka L, Haapala M, Kuuranne T, et al. Corrigendum to "Analysis of anabolic steroids in urine by gas chromatography-microchip atmospheric pressure photoionization-mass spectrometry with chlorobenzene as dopant" [J. Chromatogr. A 1312 (2013) 111-117]. J Chromatogr A. 2016;1448:128doi: 10.1016/j.chroma.2016.04.059.
Hintikka, L., Haapala, M., Kuuranne, T., Leinonen, A., & Kostiainen, R. (2016). Corrigendum to "Analysis of anabolic steroids in urine by gas chromatography-microchip atmospheric pressure photoionization-mass spectrometry with chlorobenzene as dopant" [J. Chromatogr. A 1312 (2013) 111-117]. Journal of chromatography. A, 1448128. https://doi.org/10.1016/j.chroma.2016.04.059
Hintikka, Laura, et al. "Corrigendum to "Analysis of anabolic steroids in urine by gas chromatography-microchip atmospheric pressure photoionization-mass spectrometry with chlorobenzene as dopant" [J. Chromatogr. A 1312 (2013) 111-117]." Journal of chromatography. A vol. 1448 (2016): 128. doi: https://doi.org/10.1016/j.chroma.2016.04.059
Hintikka L, Haapala M, Kuuranne T, Leinonen A, Kostiainen R. Corrigendum to "Analysis of anabolic steroids in urine by gas chromatography-microchip atmospheric pressure photoionization-mass spectrometry with chlorobenzene as dopant" [J. Chromatogr. A 1312 (2013) 111-117]. J Chromatogr A. 2016 May 27;1448:128. doi: 10.1016/j.chroma.2016.04.059. Epub 2016 Apr 28. PMID: 27133863.
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Ultrasonically aided mineral processing technique for remediation of soil contaminated by heavy metals.

Ultrasonics sonochemistry

Kyllönen H, Pirkonen P, Hintikka V, Parvinen P, Grönroos A, Sekki H.
PMID: 15081983
Ultrason Sonochem. 2004 May;11(3):211-6. doi: 10.1016/j.ultsonch.2004.01.024.

In this study, power ultrasound was used as aiding method for the mineral processing technique, which have recently been developed for the remediation of soil contaminated by heavy metal containing bullets, their broken parts and alteration products. Power ultrasound...

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Kyllönen H, Pirkonen P, Hintikka V, et al. Ultrasonically aided mineral processing technique for remediation of soil contaminated by heavy metals. Ultrason Sonochem. 2004;11(3):211-6doi: 10.1016/j.ultsonch.2004.01.024.
Kyllönen, H., Pirkonen, P., Hintikka, V., Parvinen, P., Grönroos, A., & Sekki, H. (2004). Ultrasonically aided mineral processing technique for remediation of soil contaminated by heavy metals. Ultrasonics sonochemistry, 11(3), 211-6. https://doi.org/10.1016/j.ultsonch.2004.01.024
Kyllönen, Hanna, et al. "Ultrasonically aided mineral processing technique for remediation of soil contaminated by heavy metals." Ultrasonics sonochemistry vol. 11,3 (2004): 211-6. doi: https://doi.org/10.1016/j.ultsonch.2004.01.024
Kyllönen H, Pirkonen P, Hintikka V, Parvinen P, Grönroos A, Sekki H. Ultrasonically aided mineral processing technique for remediation of soil contaminated by heavy metals. Ultrason Sonochem. 2004 May;11(3):211-6. doi: 10.1016/j.ultsonch.2004.01.024. PMID: 15081983.
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Stachybotrys atra Growth and Toxin Production in Some Building Materials and Fodder under Different Relative Humidities.

Applied and environmental microbiology

Nikulin M, Pasanen AL, Berg S, Hintikka EL.
PMID: 16349391
Appl Environ Microbiol. 1994 Sep;60(9):3421-4. doi: 10.1128/aem.60.9.3421-3424.1994.

Growth of Stachybotrys atra and its toxin production on some building materials and in animal fodder were studied at relative humidities ranging from 78 to 100%. Toxins were detected by biological assays and chemical methods. Strong growth of the...

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Nikulin M, Pasanen AL, Berg S, et al. Stachybotrys atra Growth and Toxin Production in Some Building Materials and Fodder under Different Relative Humidities. Appl Environ Microbiol. 1994;60(9):3421-4doi: 10.1128/aem.60.9.3421-3424.1994.
Nikulin, M., Pasanen, A. L., Berg, S., & Hintikka, E. L. (1994). Stachybotrys atra Growth and Toxin Production in Some Building Materials and Fodder under Different Relative Humidities. Applied and environmental microbiology, 60(9), 3421-4. https://doi.org/10.1128/aem.60.9.3421-3424.1994
Nikulin, M, et al. "Stachybotrys atra Growth and Toxin Production in Some Building Materials and Fodder under Different Relative Humidities." Applied and environmental microbiology vol. 60,9 (1994): 3421-4. doi: https://doi.org/10.1128/aem.60.9.3421-3424.1994
Nikulin M, Pasanen AL, Berg S, Hintikka EL. Stachybotrys atra Growth and Toxin Production in Some Building Materials and Fodder under Different Relative Humidities. Appl Environ Microbiol. 1994 Sep;60(9):3421-4. doi: 10.1128/aem.60.9.3421-3424.1994. PMID: 16349391; PMCID: PMC201822.
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Showing 1 to 12 of 17 entries